Research Topics
| RICK BEVINSSummaryAffiliation: University of Nebraska Country: USA Publications
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Publications
Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'Rick A Bevins
Department of Psychology, 238 Burnett Hall, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Nat Protoc 1:1306-11. 2006....
Disentangling the nature of the nicotine stimulusRick A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Processes 90:28-33. 2012..We close with a discussion of future research directions and potential implications of the research for understanding interoceptive stimuli...
Environmental familiarization in rats: differential effects of acute and chronic nicotineR A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, Nebraska 68588 0308, USA
Neurobiol Learn Mem 75:63-76. 2001..Indeed, acute nicotine (0. 2, 0.6, and 1.2 mg/kg) in the present report consistently decreased the amount of time spent with one paw on the edge of the platform; chronic nicotine did not affect this behavior...
Novelty reward as a measure of anhedoniaRick A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Neurosci Biobehav Rev 29:707-14. 2005....
Timing of conditioned responding in a nicotine locomotor conditioning preparation: manipulations of the temporal arrangement between context cues and drug administrationRick A Bevins
Department of Psychology, 238 Burnett Hall, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Brain Res 159:135-43. 2005....
Extending the role of associative learning processes in nicotine addictionRick A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Cogn Neurosci Rev 3:143-58. 2004..Future smoking intervention strategies should take into consideration these additional associative learning processes...
Individual differences in rats' reactivity to novelty and the unconditioned and conditioned locomotor effects of methamphetamineRick A Bevins
University of Nebraska Lincoln, Burnett Hall, Lincoln, NE 68588 0308, USA
Pharmacol Biochem Behav 79:65-74. 2004..This research extends the predictive variable of reactivity to inescapable novelty to methamphetamine's conditioned and unconditioned locomotor effects...
Vaccines to combat smokingRick A Bevins
University of Nebraska Lincoln, Department of Psychology, 238 Burnett Hall, Lincoln, NE 68588 0308, USA
Expert Opin Biol Ther 8:379-83. 2008..Although these therapies have had some success, relapse within a year is still high. Clearly additional strategies are needed to aid individuals in maintaining abstinence...
Characterization of nicotine's ability to serve as a negative feature in a Pavlovian appetitive conditioning task in ratsRick A Bevins
Department of Psychology, University of Nebraska Lincoln, 238 Burnett Hall, Lincoln, NE 68588 0308, USA
Psychopharmacology (Berl) 184:470-81. 2006..A negative feature signals that presentation of a conditional stimulus (CS) will not be paired with an unconditioned stimulus...
Nicotine does not produce state-dependent effects on learning in a Pavlovian appetitive goal tracking task with ratsRick A Bevins
Department of Psychology, 238 Burnett Hall, University of Nebraska Lincoln, Lincoln, NE 68588 0308, United States
Behav Brain Res 177:134-41. 2007....
Pavlovian drug discrimination with bupropion as a feature positive occasion setter: substitution by methamphetamine and nicotine, but not cocaineJamie L Wilkinson
Department of Psychology, University of Nebraska Lincoln, USA
Addict Biol 14:165-73. 2009..The overlap in stimulus properties might explain the effectiveness of bupropion as a smoking cessation aid and highlight the possible utility of bupropion for treatment of stimulant use disorder...
Novel-object place conditioning: behavioral and dopaminergic processes in expression of novelty rewardRick A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Brain Res 129:41-50. 2002....
Individual differences in rat locomotor activity are diminished by nicotine through stimulation of central nicotinic acetylcholine receptorsR A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Physiol Behav 72:237-44. 2001..This data pattern suggests that the disruptive effects of acute and chronic nicotine on individual differences were mediated by neural nicotinic acetylcholine (nACh) receptors...
Occasion setting by drug states: Functional equivalence following similar training historyMatthew I Palmatier
Department of Psychology, Kansas State University, 469 Bluemont Hall, 1100 Mid Campus Drive, Manhattan, KS 66502, USA
Behav Brain Res 195:260-70. 2008..Also, a novel or ambiguous CS did not evoke responding in the previously trained drug state, indicating that both the features (drug states) and target conditional stimuli had to be trained in discriminations before transfer could occur...
Facilitation by drug states does not depend on acquired excitatory strengthMatthew I Palmatier
Department of Psychology, University of Pittsburgh, 412 Clapp Hall, Pittsburgh, PA 15260, United States
Behav Brain Res 176:292-301. 2007..This latter finding implicates a higher-order or non-associative mechanism for facilitation of anticipatory food seeking by drug states in this Pavlovian discrimination task...
Behavioral and neuropharmacological characterization of nicotine as a conditional stimulusJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Eur J Pharmacol 561:91-104. 2007..In contrast, MK-801 decreased goal tracking on nicotine without decreasing chamber activity, indicating a role for N-methyl-D-aspartate receptors in expression of nicotine-evoked conditioned responding...
Impact of nicotine withdrawal on novelty reward and related behaviorsJoyce Besheer
Department of Psychology, University of Nebraska Lincoln, 68588 0308, USA
Behav Neurosci 117:327-40. 2003..Further investigation into the neurochemical and behavioral changes that accompany nicotine withdrawal will lead to a better understanding of the withdrawal syndrome...
Competition between the conditioned rewarding effects of cocaine and noveltyCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln 68588 0308, USA
Behav Neurosci 122:140-50. 2008..Overall, the conditioned rewarding effects of novelty competed with those of cocaine as evidenced by a change in choice behaviors motivated by drug reward...
Nicotine as a conditioned stimulus: impact of attention-deficit/hyperactivity disorder medicationsCarmela M Reichel
Department of Psychology, University of Nebraska, Lincoln, NE 68588 0308, USA
Exp Clin Psychopharmacol 15:501-9. 2007..These results suggest that atomoxetine, bupropion, and/or methylphenidate may be effective treatments for people diagnosed with ADHD and addicted to nicotine...
Acquired appetitive responding to intravenous nicotine reflects a Pavlovian conditioned associationJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Neurosci 123:97-108. 2009..Nicotine was required to be reliably paired with sucrose for control of conditioned responding to develop. Implications of these findings are discussed in relation to tobacco addiction, learning theory, and pharmacology...
Bupropion hydrochloride produces conditioned hyperactivity in ratsJamie L Wilkinson
University of Nebraska Lincoln, Department of Psychology, United States
Physiol Behav 90:790-6. 2007..However, a predictive relation between reactivity to forced novelty and the subsequent locomotor effect of bupropion may not be one of these similarities...
Examination of GABAergic and dopaminergic compounds in the acquisition of nicotine-conditioned hyperactivity in ratsMatthew I Palmatier
Department of Psychology, University of Nebraska at Lincoln, NE 68588-0308, USA
Neuropsychobiology 45:87-94. 2002..The inability of SCH-23390 to block the acquisition of nicotine-conditioned locomotor activity is notable because in past research SCH-23390 blocked expression of the learned association...
Preexposure to nicotine alters the subsequent locomotor stimulant effects of bupropion in ratsJamie L Wilkinson
Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE 68583-0398, USA
Nicotine Tob Res 8:141-6. 2006..This enhancement of the acute locomotor effects of bupropion might reflect alterations in common dopaminergic processes...
Nicotine as a signal for the presence or absence of sucrose reward: a Pavlovian drug appetitive conditioning preparation in ratsJoyce Besheer
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588-0308, USA
Psychopharmacology (Berl) 172:108-17. 2004..The conceptualization of nicotine as a CS suggests novel empirical research in which a drug acquires additional inhibitory and/or excitatory value based on other outcomes present during its effects...
Nicotine-evoked conditioned responding is dependent on concentration of sucrose unconditioned stimulusJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Processes 81:136-9. 2009..These findings are consistent with previous Pavlovian conditioning research, and extend the conditions under which the nicotine state functions as an interoceptive conditional stimulus...
Competition between novelty and cocaine conditioned reward is sensitive to drug dose and retention intervalCarmela M Reichel
Department of Psychology, University of Nebraska, USA
Behav Neurosci 124:141-51. 2010..Findings indicate that choice behaviors mediated by cocaine conditioning are reduced with the passing of time. Taken together, competition between cocaine and novelty conditioned rewards are sensitive to drug dose and retention interval...
Nicotine-conditioned locomotor sensitization in rats: assessment of the US-preexposure effectRick A Bevins
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Behav Brain Res 143:65-74. 2003..18 mg/kg dose. Thus, similar to place conditioning, nicotine preexposure can enhance the subsequent effectiveness of the nicotine US in a locomotor conditioning preparation...
Individual differences in responses to nicotine: tracking changes from adolescence to adulthoodMing Li
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Acta Pharmacol Sin 30:868-78. 2009..We also examined the possible long-term effects of adolescent nicotine exposure on adult prepulse inhibition (PPI) of the acoustic startle response, a measure of sensorimotor gating ability...
The interoceptive Pavlovian stimulus effects of caffeineJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Pharmacol Biochem Behav 86:838-46. 2007..The nature of this dissociation between caffeine as a drug feature and a CS is discussed within the context of past research finding a similar dissociation with amphetamine and chlordiazepoxide, but not with nicotine...
Methamphetamine functions as a positive and negative drug feature in a Pavlovian appetitive discrimination taskCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln, Nebraska 68588 0308, USA
Behav Pharmacol 18:755-65. 2007....
Neuropharmacology of the interoceptive stimulus properties of nicotineThomas E Wooters
Department of Psychology, BBSRB, University of Kentucky, Lexington, KY 40536 0509, USA
Curr Drug Abuse Rev 2:243-55. 2009....
Intravenous nicotine conditions a place preference in rats using an unbiased designJamie L Wilkinson
University of Nebraska Lincoln, Department of Psychology, Lincoln, NE 68588 0308, USA
Pharmacol Biochem Behav 88:256-64. 2008....
Interoceptive Pavlovian conditioning with nicotine as the conditional stimulus varies as a function of the number of conditioning trials and unpaired sucrose deliveriesJamie L Wilkinson
Department of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0308, USA
Behav Pharmacol 17:161-72. 2006..These results are consistent with the notion that nicotine-evoked goal tracking results from interoceptive conditioning processes...
Investigation of endocannabinoid modulation of conditioned responding evoked by a nicotine CS and the Pavlovian stimulus effects of CP 55,940 in adult male ratsJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Psychopharmacology (Berl) 205:655-65. 2009..Research has not investigated whether the cannabinoid system is involved in the interoceptive stimulus effects of nicotine functioning as a conditional stimulus (CS)...
Extinction with varenicline and nornicotine, but not ABT-418, weakens conditioned responding evoked by the interoceptive stimulus effects of nicotineCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln NE 68588 0308, USA
Neuropharmacology 58:1237-45. 2010..Interpretations regarding 'nicotine-like' effects of a ligand depend on the nature of the test. Understanding the processes mediating transfer of extinction learning with potential pharmacotherapies may reveal new treatment targets...
Reference place conditioning procedure with cocaine: increased sensitivity for measuring associatively motivated choice behavior in ratsCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588, USA
Behav Pharmacol 21:323-31. 2010..Experiment 4 showed that the competition at 2.5 mg/kg was not due to reward sensitization. The reference-conditioning procedure has increased the sensitivity for measuring associatively motivated choice behavior...
Forced abstinence model of relapse to study pharmacological treatments of substance use disorderCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln NE 68588 0308, USA
Curr Drug Abuse Rev 2:184-94. 2009....
Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotineAmanda M Struthers
Department of Psychology, University of Nebraska Lincoln, Lincoln NE 68588 0308, USA
Pharmacol Biochem Behav 94:319-28. 2009..1mg/kg). These results indicate that beta2* and potentially alpha3beta4* nicotinic acetylcholine receptors play a role in the CS effects of nicotine and are potential targets for the development of nicotine cessation aids...
Bupropion differentially impacts acquisition of methamphetamine self-administration and sucrose-maintained behaviorCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, USA
Pharmacol Biochem Behav 89:463-72. 2008..Combined, these results suggest that bupropion has a more general effect within the appetitive/reward system of the brain rather than having complete specificity for methamphetamine...
The conditional stimulus effects of nicotine vary as a function of training doseJennifer E Murray
Department of Psychology, University of Nebraska Lincoln, Lincoln, Nebraska 68588 0308, USA
Behav Pharmacol 18:707-16. 2007..1 mg/kg group than in the other groups. Combined, this research demonstrates that the nicotine conditional stimulus shows some variation with training dose...
Bupropion attenuates methamphetamine self-administration in adult male ratsCarmela M Reichel
Department of Psychology, University of Nebraska Lincoln, Lincoln, NE 68588 0308, United States
Drug Alcohol Depend 100:54-62. 2009..05 and 0.1 mg/kg) and sucrose deliveries. Considered together, this pattern of findings demonstrates that bupropion decreases responding for methamphetamine, but the effects are only somewhat specific...
Immunization to nicotine with a peptide-based vaccine composed of a conformationally biased agonist of C5a as a molecular adjuvantSam D Sanderson
School of Allied Health Professions, University of Nebraska Medical Center, 985155 Nebraska Medical Center, Omaha, NE 68198 5155, USA
Int Immunopharmacol 3:137-46. 2003....
Stimulus properties of nicotine, amphetamine, and chlordiazepoxide as positive features in a pavlovian appetitive discrimination task in ratsMatthew I Palmatier
Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neuropsychopharmacology 30:731-41. 2005..45 mg/kg) and amphetamine (ED50 = 3.70 mg/kg), but not for CDP. These results are consistent with the hypothesis that drug states can occasion appetitive Pavlovian CRs in a pharmacologically specific manner...
Place conditioning: what does it add to our understanding of ethanol reward?Fred O Risinger
Department of Behavioral Neuroscience, Portlannd Alcohol Research Center, Oregon Health and Science University, Portland, Oregon 97201 3098, USA
Alcohol Clin Exp Res 26:1444-52. 2002..Cunningham; and (4) Utilization of place conditioning for understanding the neuropharmacology of the rewarding effects of ethanol, by Fred O. Risinger...
Research Grants
- Acquired Appetitive Properties of NicotineRICK BEVINS; Fiscal Year: 2009....
- Acquired Appetitive Properties of NicotineRICK BEVINS; Fiscal Year: 2007..abstract_text> ..
- Acquired Appetitive Properties of NicotineRICK BEVINS; Fiscal Year: 2007..abstract_text> ..
- Reference-dose method and cocaine-conditioned choiceRICK BEVINS; Fiscal Year: 2006..That research could translate into more effective intervention strategies. ..
- PAVLOVIAN CONDITIONING PROCESSES INVOLVING NICOTINERICK BEVINS; Fiscal Year: 2001..intermittent delivery). Elucidating the behavioral processes underlying acquisition and expression of Pavlovian drug conditioning will have important implications for prevention and intervention strategies. ..
- Acquired Appetitive Properties of NicotineRick A Bevins; Fiscal Year: 2010....
