Research Topics
Genomes and Genes
Species | Marianne BerwickSummaryAffiliation: University of New Mexico Country: USA Publications
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Publications
Vitamin D and melanoma incidence and mortalityMarianne Berwick
Division of Epidemiology, Biostatistics and Preventive Medicine, Department of Internal Medicine, University of New Mexico Cancer Center, Albuquerque, NM, USA
Pigment Cell Melanoma Res 26:9-15. 2013....
Pathways to the development of melanoma: a complex issueMarianne Berwick
Department of Internal Medicine, Cancer Research and Treatment Center, University of New Mexico, 87131, Albuquerque, USA
J Invest Dermatol 126:1932-3. 2006..However, such hypotheses must be viewed in all their complexity, and the paper by Randi et al. gives additional substance to this complexity...
Association between aryl hydrocarbon receptor genotype and survival in soft tissue sarcomaMarianne Berwick
Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Clin Oncol 22:3997-4001. 2004..Accumulating evidence shows that germline polymorphisms may affect survival in cancer. The purpose of this study was to investigate the association between polymorphisms in a group of candidate genes and survival with soft tissue sarcoma...
Sun exposure and mortality from melanomaMarianne Berwick
University of New Mexico, Department of Internal Medicine, New Mexico Cancer Research Facility, MSC08 4630, Room 103A, 1 University of New Mexico, Albuquerque, NM 87131, USA
J Natl Cancer Inst 97:195-9. 2005..We therefore evaluated the association between measures of skin screening and death from cutaneous melanoma...
Are tanning beds "safe"? Human studies of melanomaMarianne Berwick
University of New Mexico Cancer Research and Treatment Center, Albuquerque, NM, USA
Pigment Cell Melanoma Res 21:517-9. 2008....
Solar UV exposure and mortality from skin tumorsMarianne Berwick
Department of Internal Medicine, University of New Mexico Cancer Center, Albuquerque, NM 87131 0001, USA
Adv Exp Med Biol 624:117-24. 2008..Understanding this conundrum is critical to present coherent public health messages and to improve the mortality rates from melanoma...
Ultraviolet radiation exposure, vitamin D, and cancerMarianne Berwick
University of New Mexico, CRF, MSC08 4630, Room 103A, 1 University of New Mexico, Albuquerque 87131, USA
Photochem Photobiol 81:1261-6. 2005..These exposures translate into 13 h per year, for a light-skinned individual, leading to 650 h of exposure from birth to age 50...
The current epidemiology of cutaneous malignant melanomaMarianne Berwick
Department of Internal Medicine, Cancer Treatment and Research Center, University of New Mexico, Albuquerque, NM 87131, USA
Front Biosci 11:1244-54. 2006..Genetic factors associated with familial melanoma have been well described and new attention, not yet validated, is being paid to low penetrant genes and their polymorphisms...
Counterpoint: sunscreen use is a safe and effective approach to skin cancer preventionMarianne Berwick
University of New Mexico, Albuquerque, NM 87131-0001, USA
Cancer Epidemiol Biomarkers Prev 16:1923-4. 2007
The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based studyMarianne Berwick
University of New Mexico, Department of Internal Medicine, New Mexico Cancer Research Facility, MSC08 4630, Room 103A, 1 University of New Mexico, Albuquerque, NM 87131, USA
Cancer Epidemiol Biomarkers Prev 15:1520-5. 2006..The results suggest that the relative risk of mutation carriers in the population may be lower than currently believed and that different mutations on the CDKN2A gene may confer substantially different risks of melanoma...
Melanoma epidemiology and public healthMarianne Berwick
Division of Epidemiology and Biostatistics, Department of Internal Medicine, 1 University of New Mexico, MSC08 4360, CRF 103A, Albuquerque, NM 87131 0001, USA
Dermatol Clin 27:205-14, viii. 2009....
Can UV exposure reduce mortality?Marianne Berwick
University of New Mexico Cancer Center, Albuquerque, New Mexico 87131 0001, USA
Cancer Epidemiol Biomarkers Prev 20:582-4. 2011..Such a finding is curious and inconsistent with a vitamin D hypothesis. These results should impel investigators to study further the biology of ultraviolet radiation, both natural and artificial, and its health effects...
The good, the bad, and the ugly of sunscreensM Berwick
University of New Mexico Cancer Center and Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
Clin Pharmacol Ther 89:31-3. 2011..Vitamin D inhibition is, at this stage, unlikely due to insufficient use by individuals. Safety of sunscreens is a concern, and sunscreen companies have emotionally and inaccurately promoted the use of sunscreens...
Invited commentary: a sunbed epidemic?Marianne Berwick
University of New Mexico Cancer Center and Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
Am J Epidemiol 172:768-70; discussion 771-772. 2010..Caution, however, must be exercised in interpreting the data because of the lack of understanding of emissions of ultraviolet radiation from sunbeds and the ecologic nature of the data...
Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sampleColin B Begg
Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Natl Cancer Inst 97:1507-15. 2005..In this study, we examined lifetime melanoma risk among CDKN2A mutation carriers using carriers who were identified in a population-based study of melanoma...
A design for cancer case-control studies using only incident cases: experience with the GEM study of melanomaColin B Begg
Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Int J Epidemiol 35:756-64. 2006..The use of a novel case-control design in which cases have second primaries and controls are cancer survivors has been proposed for this purpose...
Prospective study of sunburn and sun behavior patterns during adolescenceStephen W Dusza
Department of Medicine, Memorial Sloan Kettering Cancer Center, Dermatology Service, New York, NY 10022, USA
Pediatrics 129:309-17. 2012..Early childhood UV light radiation (UVR) exposures have been shown to be associated with melanoma development later in life. The objective of this study was to assess sunburn and changes in sunburn and sun behaviors during periadolescence...
Sun protection and skin self-examination in melanoma survivorsUrvi J Mujumdar
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Psychooncology 18:1106-15. 2009..Skin self-examination (SSE) and sun protection are standard clinical recommendations to minimize risk. In this study we examined performance of these behaviors in individuals with melanoma drawn from the general population...
Study of Nevi in Children (SONIC): baseline findings and predictors of nevus countSusan A Oliveria
Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
Am J Epidemiol 169:41-53. 2009..041), and often and always (RR = 1.32, 95% CI: 1.13, 1.54; P = 0.001) were associated with increased number of nevi. Identifying factors that predict the development of nevi will improve primary prevention efforts during early life...
CDKN2A germline mutations in individuals with cutaneous malignant melanomaIrene Orlow
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Invest Dermatol 127:1234-43. 2007..With the exception of the variant in position -34 of CDKN2A of known functional consequence, the remaining rare variants in the non-coding region have no apparent impact on risk...
Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progressionJavier Cotignola
Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Negat Results Biomed 6:9. 2007..Functional polymorphisms in MMP genes' promoter regions may modulate the risk for melanoma progression...
Vitamin D receptor polymorphisms in patients with cutaneous melanomaIrene Orlow
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Int J Cancer 130:405-18. 2012..The VDR may play a role in melanomagenesis...
The use of hierarchical models for estimating relative risks of individual genetic variants: an application to a study of melanomaMarinela Capanu
Memorial Sloan Kettering Cancer Center, 307 E 63rd Street, New York, NY 10021, U S A
Stat Med 27:1973-92. 2008..However, further research is needed to validate the application of asymptotic methods to such sparse data...
EGF gene polymorphism and the risk of incident primary melanomaKandace L Amend
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Cancer Res 64:2668-72. 2004..Additional independent studies will be required to elucidate relationships between genetic variation in the EGF gene and risk of melanoma...
Clinicopathological features of and risk factors for multiple primary melanomasCristina R Ferrone
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
JAMA 294:1647-54. 2005..9% at 5 years. CONCLUSIONS: The incidence of MPM is increased in patients with a positive family history and/or dysplastic nevi. These patients should undergo intensive dermatologic screening and should consider genetic testing...
Evaluation of the clonal origin of multiple primary melanomas using molecular profilingIrene Orlow
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
J Invest Dermatol 129:1972-82. 2009....
Dermoscopic patterns and subclinical melanocytic nests in normal-appearing skinA Scope
Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
Br J Dermatol 160:1318-21. 2009..Dermoscopic patterns of normal-appearing skin have received little scrutiny. We have recently completed an analysis of dermoscopic patterns of naevi in children...
Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanomaJavier Cotignola
Memorial Sloan Kettering Cancer Center, New York, NY, USA
BMC Med Genet 8:10. 2007..Some polymorphisms are known to influence gene expression, protein activity, stability, and interactions, and they were shown to be associated with certain tumor phenotypes and cancer risk...
Evaluation of a novel Arg-Gly-Asp-conjugated α-melanocyte stimulating hormone hybrid peptide for potential melanoma therapyJianquan Yang
College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
Bioconjug Chem 20:1634-42. 2009..The purpose of this study was to determine whether Arg-Gly-Asp (RGD)-conjugated α-melanocyte stimulating hormone (α-MSH) hybrid peptide could be employed to target melanocortin-1 (MC1) receptor for potential melanoma therapy...
Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancerEsther Erdei
Division of Epidemiology and Biostatistics, Department of Internal Medicine and University of New Mexico Cancer Center, University of New Mexico, Health Sciences Center, 2325 Camino de Salud, NE, Albuquerque, NM 87131 0001, USA
Cytokine 51:18-24. 2010..These findings might guide us to understand the presence of SNPs in cytokine genes and serum concentrations among breast cancer patients and potentially in other cancers...
Evaluation of land use regression models for NO2 in El Paso, Texas, USAMelissa Gonzales
University of New Mexico School of Medicine, Department of Internal Medicine, Division of Epidemiology and Preventive Medicine, Albuquerque, NM 97101 0001, USA
Sci Total Environ 432:135-42. 2012....
Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancerMarianne Berwick
Cancer Research and Treatment Center Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA
Cancer Res 67:9591-6. 2007..4; 95% CI, 1.1-5.2). Overall, there was no increased risk for cancer among FA heterozygotes in this study of Fanconi relatives, although there is some evidence that FANCC mutations are possibly breast cancer susceptibility alleles...
DNA damage and repair capacity in patients with lung cancer: prediction of multiple primary tumorsIrene Orlow
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Clin Oncol 26:3560-6. 2008..Therefore, we evaluated constitutive and induced DNA damage, and repair capacity, in patients with multiple NSCLCs (cases) and compared the results to those obtained in patients with a single NSCLC (controls)...
Expression of melanocyte differentiation antigens and ki-67 in nodal nevi and comparison of ki-67 expression with metastatic melanomaChristina M Lohmann
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Am J Surg Pathol 26:1351-7. 2002..Immunohistochemistry for S-100 protein, Melan-A/MART-1, or tyrosinase facilitates the recognition of melanocytes but does not distinguish between nodal nevus and metastatic melanoma...
Malignant melanoma in pregnancyCharles L Wiggins
Division of Epidemiology, Department of Internal Medicine, MSC 10 5550, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
Obstet Gynecol Clin North Am 32:559-68. 2005..Most studies found no difference in overall survival between pregnant and nonpregnant women with melanoma. Recent reports from large-scale, population-based studies support these conclusions...
A 20-year perspective on the International Fanconi Anemia Registry (IFAR)David I Kutler
Memorial Sloan-Kettering Cancer Center, New York, NY, USA
Blood 101:1249-56. 2003..The results of this study of patients registered in the IFAR over a 20-year period provide information that will enable better prediction of outcome and aid clinicians with decisions regarding major therapeutic modalities...
Incidence and survival rates for female malignant germ cell tumorsHarriet O Smith
Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5286, USA
Obstet Gynecol 107:1075-85. 2006..To evaluate 30-year, population-based trends in incidence and survival rates for malignant germ cell tumors originating within the female genital tract...
Anticipating dissemination of cancer genomics in public health: a theoretical approach to psychosocial and behavioral challengesJennifer L Hay
Memorial Sloan Kettering Cancer Center, Department of Psychiatry and Behavioral Sciences, New York, NY 10022, USA
Ann Behav Med 34:275-86. 2007..Given the recent sequencing of the human genome, genetic susceptibility information will probably be increasingly useful in the prevention and control of many common diseases, including cancer...
Effect of specific allergen inhalation on serum adiponectin in human asthmaAkshay Sood
Department of Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
Chest 135:287-94. 2009..We sought to evaluate whether allergen inhalation affects serum adiponectin in human asthma...
Reliability of mutagen sensitivity assay: an inter-laboratory comparisonEsther Erdei
University of New Mexico, School of Medicine, Department of Internal Medicine and New Mexico Cancer Research and Treatment Center, Albuquerque, NM 87131, USA
Mutagenesis 21:261-4. 2006....
Skin cancer risk discussions in melanoma-affected familiesJennifer Hay
Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10022, USA
J Cancer Educ 20:240-6. 2005..First-degree relatives (FDRs) of melanoma patients are at increased melanoma risk and thus represent an important target for prevention education. Family skin cancer risk discussions may be a useful education context...
Interpretation of melanoma risk feedback in first-degree relatives of melanoma patientsJennifer L Hay
Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, New York, NY 10022, USA
J Cancer Epidemiol 2012:374842. 2012....
Self-reported ethnicity and genetic ancestry in relation to oral cancer and pre-cancer in Puerto RicoEsther Erdei
Molecular Epidemiology Laboratory of the Division of Epidemiology and Biostatistics, Department of Internal Medicine, University of New Mexico Health Sciences Center, School of Medicine, Albuquerque, New Mexico, United States of America
PLoS ONE 6:e23950. 2011..We conducted an epidemiological study to examine risk and protective factors, in addition to possible genetic susceptibility components, for oral cancer and precancer in Puerto Rico...
UV causation of melanoma in Xiphophorus is dominated by melanin photosensitized oxidant productionSimon R Wood
Division of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
Proc Natl Acad Sci U S A 103:4111-5. 2006..This approach should be applicable to humans, thus providing an accurate surrogate for Phi(mel) for prevention studies...
Quantifying the change of melanoma incidence by Breslow thicknessJing Qin
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
Biometrics 58:665-70. 2002..Model-based cumulative distribution estimation is studied. Methodology developed in this article is applied to the Tasmania Tumor Registry data...
Participation in annual skin cancer screening among women seeking routine mammographyJennifer S Ford
Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Prev Med 38:704-12. 2004..However, little is known about the psychosocial factors related to participation in annual SCS, which remains relatively low among the general public...
Toward reduction of misclassification in the biology of melanomaMarianne Berwick
University of New Mexico, Albuquerque, New Mexico, USA
J Invest Dermatol 124:xiv. 2005
Patient adherence to skin self-examination. effect of nurse intervention with photographsSusan A Oliveria
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10022, USA
Am J Prev Med 26:152-5. 2004..All participants had baseline whole-body digital photography as part of their clinical evaluation...
Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokersKristina G Flores
Department of Internal Medicine, University of New Mexico, Albuquerque, NM 87131, USA
Carcinogenesis 33:1542-7. 2012..These studies suggest that SNPs in CBS and MTRR have sex-specific associations with aberrant methylation in the lung epithelium of smokers that could be mediated by the affected one-carbon metabolism and transsulfuration in the cells...
Temporal-spatial analysis of U.S.-Mexico border environmental fine and coarse PM air sample extract activity in human bronchial epithelial cellsFredine T Lauer
The University of New Mexico Center for Environmental Health Sciences, Albuquerque, NM 87131, USA
Toxicol Appl Pharmacol 238:1-10. 2009..Spatially, the greatest gene expression increases were seen in extracts collected from the central most areas of El Paso which are also closest to highways and border crossings...
Replacement of the Lys linker with an Arg linker resulting in improved melanoma uptake and reduced renal uptake of Tc-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptideJianquan Yang
College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
Bioorg Med Chem 18:6695-700. 2010....
Sentinel lymph node biopsy in patients with diagnostically controversial spitzoid melanocytic tumorsChristina M Lohmann
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 26:47-55. 2002....
Symptoms and signs of primary melanoma: important indicators of Breslow depthBenjamin P Negin
Yale University School of Medicine, New Haven, Connecticut, USA
Cancer 98:344-8. 2003..Understanding this relationship can be valuable in patient management, especially when pathologic data are incomplete or inconsistent with the patient's history...
Cutaneous melanin density of Caucasians measured by spectrophotometry and risk of malignant melanoma, basal cell carcinoma, and squamous cell carcinoma of the skinTerence Dwyer
Menzies Centre for Population Health Research, University of Tasmania, Hobart, Tasmania, Australia
Am J Epidemiol 155:614-21. 2002..The authors conclude that, particularly for men, cutaneous melanin density at the upper inner arm is a strong predictor of risk of skin cancer...
The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme functionKristin L Lockett
Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, North Carolina, 27157, USA
Cancer Res 64:6344-8. 2004..This study is the first to provide evidence that the ADPRT V762A-genetic variant contributes to CaP susceptibility and altered ADPRT/PARP-1 enzyme function in response to oxidative damage...
Tandem BRAF mutations in primary invasive melanomasNancy E Thomas
Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA
J Invest Dermatol 122:1245-50. 2004..The finding of tandem mutations in thin melanomas makes it more likely that they arise as a simultaneous rather than sequential event...
Ambient UVB and melanoma risk in the United States: a case-control analysisC Suzanne Lea
Department of Epidemiology and Public Health Biology, University of California, Berkeley, Berkeley, CA USA
Ann Epidemiol 17:447-53. 2007..This study assessed cumulative UVB using a ground-based measurement instrument to estimate the association between UVB and melanoma...
Does the addition of information on genotype improve prediction of the risk of melanoma and nonmelanoma skin cancer beyond that obtained from skin phenotype?Terence Dwyer
Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
Am J Epidemiol 159:826-33. 2004..4% (cutaneous malignant melanoma), 3.2% (basal cell carcinoma), or 2.0% (squamous cell carcinoma). The improvement in prediction was probably too small to be valuable in a clinical setting...
Randomized, placebo-controlled pilot trial of the effects of alpha-tocopherol supplementation on levels of autoantibodies against 5-hydroxymethyl-2-deoxyuridine in melanoma patientsSomdat Mahabir
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Insitute, Bethesda, Maryland 20892 8314, USA
Melanoma Res 14:49-56. 2004..Further studies using much larger sample sizes are required to confirm this finding...
Lung cancer risk in white and black AmericansSteven D Stellman
American Health Foundation, One Dana Road, Valhalla, NY 10595, USA
Ann Epidemiol 13:294-302. 2003....
Re: A prospective study of pigmentation, sun exposure, and risk of cutaneous malignant melanoma in womenDeAnn Lazovich
J Natl Cancer Inst 96:335; author reply 337-8. 2004
Numerous, small, darkly pigmented melanocytic nevi: the cheetah phenotypePhung M Huynh
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Acad Dermatol 48:707-13. 2003....
The importance of mitotic rate as a prognostic factor for localized cutaneous melanomaRaymond L Barnhill
Department of Dermatology, George Washington University Medical Center, Washington, DC, USA
J Cutan Pathol 32:268-73. 2005..When both TU and MR are included in the same analysis, MR appears to be the more important than TU and TU loses its significance as an independent prognostic factor...
Gene-environment interactions: how many false positives?Giuseppe Matullo
J Natl Cancer Inst 97:550-1. 2005
Family communication after melanoma diagnosisJennifer Hay
Arch Dermatol 144:553-4. 2008
Evaluating early detection in the diagnosis of melanomaMarianne Berwick
Arch Dermatol 142:1485-6. 2006
Ambient UV, personal sun exposure and risk of multiple primary melanomasAnne Kricker
School of Public Health, University of Sydney, Edward Ford Building A27, NSW, 2006, Australia, and Women s College Hospital, Toronto, ON, Canada
Cancer Causes Control 18:295-304. 2007..Sun exposure is the main cause of melanoma in populations of European origin. No previous study has examined the effect of sun exposure on risk of multiple primary melanomas compared with people who have one melanoma...
Could BRAF mutations in melanocytic lesions arise from DNA damage induced by ultraviolet radiation?Nancy E Thomas
Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA
J Invest Dermatol 126:1693-6. 2006..We propose a mechanism for their origin, taking into consideration melanocytic-specific BRAF tandem mutations, nearby potential pyrimidine dimer sites, the properties of specialized DNA polymerases, and biological selection...
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotypeReinhard Kalb
Department of Human Genetics, University of Wurzburg, Wurzburg, Germany
Am J Hum Genet 80:895-910. 2007..Although hypomorphic mutations arie involved, clinically, these patients have a relatively severe form of FA...
Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanomaNancy E Thomas
Department of Dermatology, University of North Carolina, Chapel Hill, NC 27599, USA
Cancer Epidemiol Biomarkers Prev 16:991-7. 2007..The association of BRAF mutations with early-life UV exposure provides evidence in support of childhood sun protection for melanoma prevention...
Distance to diagnosing provider as a measure of access for patients with melanomaKaryn B Stitzenberg
Department of Surgery, School of Medicine, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg, CB 7213, Chapel Hill, NC 27599 7213, USA
Arch Dermatol 143:991-8. 2007..To examine the effect of travel distance and other sociodemographic factors on access to a diagnosing provider for patients with melanoma...
XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE reviewMaurizio Manuguerra
Section of Epidemiology, ISI Foundation, Torino, Italy
Am J Epidemiol 164:297-302. 2006....
Anthropometric factors and risk of melanoma in women: a pooled analysisCatherine M Olsen
Cancer and Population Studies Group, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, QLD, Australia
Int J Cancer 122:1100-8. 2008..In aggregate, data from these studies suggest that greater height and weight gain may be risk factors for cutaneous melanoma in women...
Epidemiologic support for melanoma heterogeneity using the Surveillance, Epidemiology, and End Results ProgramAnne M Lachiewicz
J Invest Dermatol 128:243-5. 2008
Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) programAnne M Lachiewicz
Department of Dermatology, University of North Carolina, Chapel Hill, 3100 Thurston Bowles Bldg, Manning Drive, CB No 7287, Chapel Hill, NC 27599 7287, USA
Arch Dermatol 144:515-21. 2008..To compare the prognosis of patients with scalp or neck (scalp/neck) melanomas with that of patients with melanomas at other sites in a large, population-based national data set controlling for known prognostic factors...
Epidemiologic support for melanoma heterogeneity using the surveillance, epidemiology, and end results programAnne M Lachiewicz
J Invest Dermatol 128:1340-2. 2008
Breslow depth of cutaneous melanoma: impact of factors related to surveillance of the skin, including prior skin biopsies and family history of melanomaNina M Fisher
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Acad Dermatol 53:393-406. 2005....
Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the Genes Environment and Melanoma StudyRobert C Millikan
Department of Epidemiology, CB 7435, School of Public Health, University of North Carolina, Chapel Hill, NC 27599, USA
Carcinogenesis 27:610-8. 2006..ORs for XPD and XPC genotypes were stronger for melanoma diagnosed at an early age, but tests for interaction were not statistically significant. The results provide further evidence for a role of XPD in the etiology of melanoma...
UV or not UV: metals are the answerFrank L Meyskens
Department of Medicine and Biological Chemistry, Chao Family Comprehensive Cancer Center, University of California-Irvine, Orange, California 92668, USA
Cancer Epidemiol Biomarkers Prev 17:268-70. 2008
Atypical cellular blue nevi (cellular blue nevi with atypical features): lack of consensus for diagnosis and distinction from cellular blue nevi and malignant melanoma ("malignant blue nevus")Raymond L Barnhill
Department of Dermatology, University of Miami Miller School of Medicine, Miami, FL, USA
Am J Surg Pathol 32:36-44. 2008....
Melanoma early detection with thorough skin self-examination: the "Check It Out" randomized trialMartin A Weinstock
Dermatoepidemiology Unit, VA Medical Center Providence, Brown University, 830 Chalkstone Avenue, Providence, RI 02908, USA
Am J Prev Med 32:517-24. 2007..Monthly thorough skin self-examination (TSSE) is an important practice for early melanoma detection that is performed by a small minority of the population...
The population dynamics of cancer: a Darwinian perspectivePaolo Vineis
Department of Epidemiology and Public Health, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PG, London, UK
Int J Epidemiol 35:1151-9. 2006....
Melanoma: is more diagnosis better?Marianne Berwick
J Gen Intern Med 21:800. 2006
Measuring DNA repair capacity: small stepsMarianne Berwick
J Natl Cancer Inst 97:84-5. 2005
Roadmap for new opportunities in melanoma researchMeenhard Herlyn
Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA 19104, USA
Semin Oncol 34:566-76. 2007..This group provides recommendations for both short- and long-term strategies that build on research strengths and opportunities established by the many members of the research community...
Research Grants
- Solar Exposure and Melanoma SurvivalMarianne Berwick; Fiscal Year: 2009..2. Determine whether functional polymorphic variants in the vitamin D receptor affect survival from melanoma. 3. Investigate the interaction of lifetime solar exposure and polymorphisms in VDR and its effect on survival. ..
- The Risk of Cancer in Fanconi Anemia HeterozygotesMarianne Berwick; Fiscal Year: 2005..Analyses will be undertaken to evaluate the role of Fanconi anemia heterozygosity for cancer. If carriers are found to be at increased risk, this information can be used to target individuals for cancer prevention strategies. ..
- A MODEL FOR GENETIC SUSCEPTIBILITY: MELANOMAMarianne Berwick; Fiscal Year: 2003..It has substantial potential for application to other areas of cancer susceptibility. ..
