Olivier Berton

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Are we getting closer to valid translational models for major depression?
    Olivier Berton
    Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, PA 19104, USA
    Science 338:75-9. 2012
  2. ncbi Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease
    Olivier Berton
    Department of Psychiatry, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104 3403, USA
    Biol Psychiatry 66:554-61. 2009
  3. ncbi Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Cell 131:391-404. 2007
  4. ncbi Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 107:4436-41. 2010
  5. ncbi The use of animal models in psychiatric research and treatment
    Vaishnav Krishnan
    Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Blvd, NE5.110, Dallas, TX 75390-9070, USA
    Am J Psychiatry 165:1109. 2008
  6. ncbi Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses
    Olivier Berton
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Neuron 55:289-300. 2007
  7. ncbi Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice
    Terry Gemelli
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    Biol Psychiatry 59:468-76. 2006

Research Grants

  1. Role of HDAC6 in a murine model of affective disorder and antidepressant action
    Olivier Berton; Fiscal Year: 2010

Collaborators

Detail Information

Publications7

  1. ncbi Are we getting closer to valid translational models for major depression?
    Olivier Berton
    Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, PA 19104, USA
    Science 338:75-9. 2012
    ..We review recent progress and highlight some of the best leads to diversify and improve discovery end points for preclinical depression research...
  2. ncbi Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease
    Olivier Berton
    Department of Psychiatry, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104 3403, USA
    Biol Psychiatry 66:554-61. 2009
    ..Previous studies in rodents have shown that striatal DeltaFosB levels accurately predict dyskinesia severity and indicate that this transcription factor may play a causal role in the dyskinesia sensitization process...
  3. ncbi Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    Vaishnav Krishnan
    Department of Psychiatry, The University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Cell 131:391-404. 2007
    ....
  4. ncbi Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance
    Diane C Lagace
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Proc Natl Acad Sci U S A 107:4436-41. 2010
    ....
  5. ncbi The use of animal models in psychiatric research and treatment
    Vaishnav Krishnan
    Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Blvd, NE5.110, Dallas, TX 75390-9070, USA
    Am J Psychiatry 165:1109. 2008
  6. ncbi Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses
    Olivier Berton
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Neuron 55:289-300. 2007
    ..These results indicate that IS-induced accumulation of DeltaFosB in the vlPAG desensitizes substance P neurons enriched in this area and opposes behavioral despair by promoting active defense responses...
  7. ncbi Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice
    Terry Gemelli
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9070, USA
    Biol Psychiatry 59:468-76. 2006
    ..Methyl-CpG binding protein 2 is a transcriptional repressor that is widely expressed in all tissues...

Research Grants1

  1. Role of HDAC6 in a murine model of affective disorder and antidepressant action
    Olivier Berton; Fiscal Year: 2010
    ..In the present project we propose to evaluate, using animal models, the potential of histone deacetylase 6 (HDAC6) as a new therapeutic target for antidepressant treatments. ..