J M Bernstein

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint The microbial ecology and immunology of the adenoid: implications for otitis media
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo 14222, USA
    Ann N Y Acad Sci 830:19-31. 1997
  2. ncbi request reprint Molecular typing of paired bacterial isolates from the adenoid and lateral wall of the nose in children undergoing adenoidectomy: implications in acute rhinosinusitis
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY, USA
    Otolaryngol Head Neck Surg 125:593-7. 2001
  3. ncbi request reprint Superantigen hypothesis for the early development of chronic hyperplastic sinusitis with massive nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    Curr Opin Otolaryngol Head Neck Surg 13:39-44. 2005
  4. ncbi request reprint Immunologic aspects of otitis media
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 2430 North Forest Road, Getzville 14068, USA
    Curr Allergy Asthma Rep 2:309-15. 2002
  5. ncbi request reprint Lymphocyte subpopulations and cytokines in nasal polyps: is there a local immune system in the nasal polyp?
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Otolaryngol Head Neck Surg 130:526-35. 2004
  6. ncbi request reprint A superantigen hypothesis for the pathogenesis of chronic hyperplastic sinusitis with massive nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Am J Rhinol 17:321-6. 2003
  7. ncbi request reprint Detection of intracytoplasmic cytokines by flow cytometry in adenoids and peripheral blood lymphocytes of children
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Ann Otol Rhinol Laryngol 110:442-6. 2001
  8. ncbi request reprint Role of IgE-mediated hypersensitivity in otitis media with effusion: pathophysiologic considerations
    J M Bernstein
    Department of Otolaryngology, State University of New York at Buffalo
    Ann Otol Rhinol Laryngol Suppl 163:15-9. 1994
  9. ncbi request reprint Update on the molecular biology of nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, USA
    Otolaryngol Clin North Am 38:1243-55. 2005
  10. pmc Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA
    Laryngoscope 119:1258-64. 2009

Collaborators

Detail Information

Publications18

  1. ncbi request reprint The microbial ecology and immunology of the adenoid: implications for otitis media
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo 14222, USA
    Ann N Y Acad Sci 830:19-31. 1997
    ..influenzae. Finally, the induction of specific SIgA by conserved outer membrane protein antigens of potential pathogens may be another strategy in the prevention of colonization of potential bacterial pathogens in the nasopharynx...
  2. ncbi request reprint Molecular typing of paired bacterial isolates from the adenoid and lateral wall of the nose in children undergoing adenoidectomy: implications in acute rhinosinusitis
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, NY, USA
    Otolaryngol Head Neck Surg 125:593-7. 2001
    ..The purpose of this study was to compare the molecular biological profiles of potential pathogens found in the nasopharynx and lateral wall of the nose concomittantly in children undergoing surgery for upper respiratory tract disease...
  3. ncbi request reprint Superantigen hypothesis for the early development of chronic hyperplastic sinusitis with massive nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    Curr Opin Otolaryngol Head Neck Surg 13:39-44. 2005
    ..The exotoxins may act as superantigens and cause activation and clonal expansion of lymphocytes with specific Vbeta regions, resulting in massive cytokine production...
  4. ncbi request reprint Immunologic aspects of otitis media
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 2430 North Forest Road, Getzville 14068, USA
    Curr Allergy Asthma Rep 2:309-15. 2002
    ..Finally, a review of alternative approaches to the prevention of otitis media is briefly discussed in this critical period of emergence of resistant bacteria to available antibiotics...
  5. ncbi request reprint Lymphocyte subpopulations and cytokines in nasal polyps: is there a local immune system in the nasal polyp?
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Otolaryngol Head Neck Surg 130:526-35. 2004
    ..This information may allow us to determine whether the source of these lymphocytes is from peripheral blood, the common mucosal immune system, or both...
  6. ncbi request reprint A superantigen hypothesis for the pathogenesis of chronic hyperplastic sinusitis with massive nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Am J Rhinol 17:321-6. 2003
    ..However, the initial trigger that causes inflammation of the lateral wall of the nose to up-regulate lymphocytes and eosinophils is still unknown...
  7. ncbi request reprint Detection of intracytoplasmic cytokines by flow cytometry in adenoids and peripheral blood lymphocytes of children
    J M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Ann Otol Rhinol Laryngol 110:442-6. 2001
    ..Finally, as shown in our previous studies, the Th2 cytokines appear to be produced in similar quantities in both adenoidal and peripheral blood lymphocytes...
  8. ncbi request reprint Role of IgE-mediated hypersensitivity in otitis media with effusion: pathophysiologic considerations
    J M Bernstein
    Department of Otolaryngology, State University of New York at Buffalo
    Ann Otol Rhinol Laryngol Suppl 163:15-9. 1994
    ..The prolonged obstruction of the eustachian tube with mucus results in middle ear inflammation, mucosal metaplasia, and increased glandular activities, all of which are hallmarks of chronic otitis media with effusion...
  9. ncbi request reprint Update on the molecular biology of nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14260, USA
    Otolaryngol Clin North Am 38:1243-55. 2005
    ..Finally, the use of topical diuretics such as amiloride and furosemide has been studied and the initial responses seem to be encouraging...
  10. pmc Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA
    Laryngoscope 119:1258-64. 2009
    ....
  11. ncbi request reprint The molecular biology of nasal polyposis
    J M Bernstein
    Departments of Otolaryngology and Pediatrics, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA
    Curr Allergy Asthma Rep 1:262-7. 2001
    ....
  12. ncbi request reprint Interference of nontypeable Haemophilus influenzae and Moraxella catarrhalis by Streptococcus oralis in adenoid organ culture: a possible strategy for the treatment of the otitis-prone child
    Joel M Bernstein
    Division of Infectious Diseases, Children s Hospital of Buffalo, New York, USA
    Ann Otol Rhinol Laryngol 111:696-700. 2002
    ..It is therefore possible that colonization with inhibitory strains of viridans streptococci may be used in the nasopharynx as a relatively safe and inexpensive approach to prevention of recurrent otitis media in some children...
  13. ncbi request reprint Localization and quantitation of eotaxin mRNA in human nasal polyps
    R J Molinaro
    Department of Biotechnical and Clinical Laboratory Sciences, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14214, USA
    Immunol Invest 32:143-54. 2003
    ..Our findings suggest that eosinophilia in NPs is likely a self-amplification process whereby increasing numbers of eosinophils are recruited to enter the polyp as a result of production of eotaxin by eosinophils already within the polyp...
  14. ncbi request reprint Human nasal polyp microenvironment maintained in viable and functional states as xenografts in SCID mice
    Joel M Bernstein
    Department of Otolaryngology and Pediatrics, School of Medicine and Biomedical Science, 3435 Main St, Buffalo, NY 14214, USA
    Ann Otol Rhinol Laryngol 115:65-73. 2006
    ..We undertook to maintain human nasal polyp tissue in a viable and functional state in SCID (severe combined immunodeficiency) mice...
  15. ncbi request reprint IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells
    Lori Broderick
    Department of Microbiology and Immunology, 138 Farber Hall, State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214, USA
    Clin Immunol 118:159-69. 2006
    ....
  16. ncbi request reprint Bacterial interference of penicillin-sensitive and -resistant Streptococcus pneumoniae by Streptococcus oralis in an adenoid organ culture: implications for the treatment of recurrent upper respiratory tract infections in children and adults
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, USA
    Ann Otol Rhinol Laryngol 115:350-6. 2006
    ..The role of the viridans group of streptococci (Streptococcus oralis) in the prevention of colonization with Streptococcus pneumoniae was investigated in an adenoid organ culture system...
  17. pmc Human nasal polyp microenvironments maintained in a viable and functional state as xenografts in NOD-scid IL2rgamma(null) mice
    Joel M Bernstein
    Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    Ann Otol Rhinol Laryngol 118:866-75. 2009
    ....
  18. ncbi request reprint Treatment of recurrent chronic hyperplastic sinusitis with nasal polyposis
    Desiderio Passali
    ENT Department, University of Siena Medical School, Siena, Italy
    Arch Otolaryngol Head Neck Surg 129:656-9. 2003
    ....