Research Topics
| IRA MARK BERNSTEINSummaryAffiliation: University of Vermont Country: USA Publications
Research Grants
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Detail Information
Publications
The relationship of plasma volume, sympathetic tone, and proinflammatory cytokines in young healthy nonpregnant womenIra M Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
Reprod Sci 16:980-5. 2009..Preeclampsia has been associated with elevated proinflammatory markers, increased sympathetic activity, and decreased plasma volume (PV). We hypothesized that these associations would be identified in women prior to a first pregnancy...
The influence of pregnancy on arterial complianceIra M Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont, USA
Obstet Gynecol 105:621-5. 2005..To examine the effect of pregnancy and the interval between pregnancies on arterial compliance as measured by mean arterial pressure (MAP) and pulse pressure...- Maternal smoking and its association with birth weightIra M Bernstein
Department of Obstetrics and Gynecology, Burgess 217, FAHC, University of Vermont, Burlington, VT 05401 1435, USA
Obstet Gynecol 106:986-91. 2005..Maternal smoking has been associated with a reduction in newborn birth weight. We sought to estimate how the pattern of maternal smoking throughout pregnancy influences newborn size... - Fetal body compositionIra Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine and Women s Health Care Service, Fletcher Allen Health Care, Burlington, VT 05401 1435, USA
Curr Opin Clin Nutr Metab Care 8:613-7. 2005.... - Pulse pressure and arterial compliance prior to pregnancy and the development of complicated hypertension during pregnancySarah Hale
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, VT 05405, USA
Reprod Sci 17:871-7. 2010..With accurate prediction of CH before pregnancy, initiation of preventative measures could begin earlier, either prior to or in early pregnancy, potentially increasing preventative efficacy and decreasing CH... 
Optimal growth modelingShane Reeves
Department of Maternal Fetal Medicine, Women s Health Care Service, Fletcher Allen Health Care, University of Vermont College of Medicine, Burlington, VT, USA
Semin Perinatol 32:148-53. 2008..This review examines the performance of a variety of the growth characterizing standards that have been employed to define abnormal growth and examines their performance in the prediction of adverse perinatal outcome...- Uterine artery hemodynamic adaptations through the menstrual cycle into early pregnancyIra M Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine and Fletcher Allen Health Care, Burlington, Vermont, USA
Obstet Gynecol 99:620-4. 2002..To estimate the time course of human uterine artery vascular adaptation through the menstrual cycle into early pregnancy... - Derivation of lung epithelium from human cord blood-derived mesenchymal stem cellsViranuj Sueblinvong
Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
Am J Respir Crit Care Med 177:701-11. 2008..Human umbilical cord blood contains both hematopoietic and nonhematopoietic stem cells, which have been used clinically as an alternative to bone marrow transplantation for hematologic malignancies and other diseases... - Effects of voucher-based incentives on abstinence from cigarette smoking and fetal growth among pregnant womenSarah H Heil
Departments of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Addiction 103:1009-18. 2008..This study examined whether voucher-based reinforcement therapy (VBRT) contingent upon smoking abstinence during pregnancy is an effective method for decreasing maternal smoking during pregnancy and improving fetal growth... - Depressive symptoms predict smoking status among pregnant womenTeresa J Linares Scott
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Addict Behav 34:705-8. 2009..These results suggest that depressive symptoms may be an independent contributor to the problem of continued smoking during pregnancy, which may have implications for smoking-cessation interventions among pregnant women... - Educational disadvantage and cigarette smoking during pregnancyStephen T Higgins
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Drug Alcohol Depend 104:S100-5. 2009..We suggest that strategies to increase educational attainment be included with more conventional tobacco-control policies in efforts to reduce smoking among girls and young women... - Effects of cigarette smoking cessation on breastfeeding durationTara M Higgins
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Nicotine Tob Res 12:483-8. 2010..Correlational studies have confirmed associations between smoking status and breastfeeding duration, but whether smoking cessation increases breastfeeding duration has not been established... - Effects of smoking cessation with voucher-based contingency management on birth outcomesStephen T Higgins
Department of Psychiatry, University of Vermont, 1 South Prospect Street, Burlington, VT 05401, USA
Addiction 105:2023-30. 2010..This study examined whether smoking cessation using voucher-based contingency management (CM) improves birth outcomes... - Predictors of postpartum relapse to smokingLaura J Solomon
Department of Psychology, University of Vermont, Burlington, VT 05405 0134, USA
Drug Alcohol Depend 90:224-7. 2007..Most women's first postpartum cigarettes were unplanned, in the presence of another smoker, and while experiencing negative affect. The findings suggest targets for interventions to reduce postpartum relapse... - Biochemical verification of smoking status in pregnant and recently postpartum womenStephen T Higgins
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Exp Clin Psychopharmacol 15:58-66. 2007.... - Characterizing nicotine withdrawal in pregnant cigarette smokersSarah H Heil
Department of Psychiatry, University of Vermont, Burlington, USA
Exp Clin Psychopharmacol 14:165-70. 2006..The results also suggest that pregnant smokers generally may have elevated baseline levels of withdrawal, which need to be considered in the design and analysis of future studies... - The assessment of newborn sizeIra M Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, VT 05401-1435, USA
Pediatrics 111:1430-1. 2003 - Examining maternal weight gain during contingency-management treatment for smoking cessation among pregnant womenYukiko Washio
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Drug Alcohol Depend 114:73-6. 2011..This study shows no evidence of excessive maternal weight gain among pregnant women receiving a CM intervention for smoking cessation... - A pilot study on voucher-based incentives to promote abstinence from cigarette smoking during pregnancy and postpartumStephen T Higgins
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Nicotine Tob Res 6:1015-20. 2004..The magnitude of these treatment effects exceed levels typically observed with pregnant and recently postpartum smokers, and the maintenance of effects through 24 weeks postpartum extends the duration beyond those reported previously... - The effect of estradiol and progesterone on knee and ankle joint laxityBruce D Beynnon
Department of Orthopaedics and Rehabilitation, Stafford Hall, Room 438A, University of Vermont, Burlington, VT 05405 0084, USA
Am J Sports Med 33:1298-304. 2005..Little is known about whether joint laxity varies cyclically during the menstrual cycle and if so, whether it is modulated by cyclic variations of estradiol (E2) and progesterone (P4)... - The relationship between menstrual cycle phase and anterior cruciate ligament injury: a case-control study of recreational alpine skiersBruce D Beynnon
Department of Orthopaedics and Rehabilitation, McClure Musculoskeletal Research Center, Stafford Hall, Room 438A, University of Vermont, Burlington, VT 05405 0084, USA
Am J Sports Med 34:757-64. 2006..Female athletes suffer a greater incidence of anterior cruciate ligament tears compared with male athletes when participating in common sports; however, very little is known about the factors that explain this disparity... - Smoking status in the initial weeks of quitting as a predictor of smoking-cessation outcomes in pregnant womenStephen T Higgins
Department of Psychiatry, University of Vermont, Burlington, VT 05401, USA
Drug Alcohol Depend 85:138-41. 2006..Any smoking during the initial 2 weeks of attempting to quit predicts poor short- and longer-term outcomes in the general population of cigarette smokers. The present study examined whether that rule applies to pregnant women... - Psychological symptoms following smoking cessation in pregnant smokersLaura J Solomon
Departments of Family Medicine and Psychology, University of Vermont, Vermont 05405, USA
J Behav Med 29:151-60. 2006..These findings should temper concerns that quitting smoking may have detrimental psychological consequences during pregnancy... - Uterine blood flow response to alpha-adrenergic blockade in nulligravid women of reproductive ageDana P Damron
Department of Obstetrics Gyencology, University of Vermont College of Medicine, Burlington, Vermont, USA
J Soc Gynecol Investig 11:388-92. 2004..Elevated uterine artery resistance has been associated with the development of preeclampsia. We sought to determine if the human uterine arterial circulation was more sensitive to alpha-adrenergic blockade than a control vascular bed... - Relationship between prepregnancy and early pregnancy uterine blood flow and resistance indexSarah A Hale
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont 05404, USA
Reprod Sci 16:1091-6. 2009..44, P = .068). Prepregnancy UBF may be a determinant of early pregnancy UBF and UBF may have independent value as a predictor of adverse pregnancy outcome... - Resistance artery adaptation to pregnancy counteracts the vasoconstricting influence of plasma from normal pregnant womenOdul A Amburgey
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
Reprod Sci 17:29-39. 2010..The increased reactivity and tone noted in NP vessels was abolished when pregnant plasma was perfused through LP arteries, suggesting these vessels adapt during pregnancy to the vasoconstricting influence of pregnant plasma... - Seasonal variation in preeclampsia based on timing of conceptionJ K Phillips
Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont 05401-1435, USA
Obstet Gynecol 104:1015-20. 2004..The highest incidence of preeclampsia was associated with conception in the summer months. LEVEL OF EVIDENCE: II-2... - Relationship of plasma volume to sympathetic tone in nulliparous womenIra M Bernstein
Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, USA
Am J Obstet Gynecol 188:938-42. 2003..These findings are consistent with an adaptive physiologic response that is aimed at the maintenance of blood pressure in the face of reduced plasma volume... - Sildenafil increases uterine blood flow in nonpregnant nulliparous womenSarah A Hale
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont 05405, USA
Reprod Sci 17:358-65. 2010..Overall, women in the luteal phase demonstrated a significant increase in UVF in response to sildenafil. However, this increase appears to be directly associated with basal UVF... - Maternal hemoglobin concentration and its association with birth weight in newborns of mothers with preeclampsiaOdul A Amburgey
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont College of Medicine, Burlington, Vermont, USA
J Matern Fetal Neonatal Med 22:740-4. 2009..We sought to determine whether birth weight would show an inverse relationship to hemoglobin concentration in a group of infants whose mothers had preeclampsia, where plasma volume constriction is common... - Evidence for distinct preterm and term phenotypes of preeclampsiaJulie K Phillips
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Vermont, Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, Vermont, USA
J Matern Fetal Neonatal Med 23:622-6. 2010..To determine differences in maternal and fetal characteristics in pregnancies complicated by preterm versus term preeclampsia...
Research Grants
- Prepregnancy Phenotype & Predisposition to Pre-eclampsiaIra Bernstein; Fiscal Year: 2007..This study proposes to evaluate a novel hypothesis that synthesizes apparently contradictory data into a single coherent theory. ..
- UTERINE VASCULAR RESPONSE TO STEROID SIGNALINGIra Bernstein; Fiscal Year: 2002..abstract_text> ..
- Prepregnancy Phenotype and Predisposition to PreeclampsiaIRA MARK BERNSTEIN; Fiscal Year: 2010..In addition, we are looking to understand the influence of pregnancy- specific, physiologic adaptations to the pathophysiologic associations of preeclampsia in a group of women at risk for developing preeclampsia. ..