HAROLD BERNSTEIN

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors
    Carissa Ritner
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e16004. 2011
  2. pmc The promise of human embryonic stem cells in aging-associated diseases
    Odessa Yabut
    Cardiovascular Research Institute, San Francisco, CA 94143, USA
    Aging (Albany NY) 3:494-508. 2011
  3. pmc miR-125b promotes early germ layer specification through Lin28/let-7d and preferential differentiation of mesoderm in human embryonic stem cells
    Sharon S Y Wong
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e36121. 2012
  4. doi request reprint Cardiac repair and restoration using human embryonic stem cells
    Harold S Bernstein
    Department of Pediatrics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143 1346, USA
    Regen Med 7:697-712. 2012
  5. pmc Strategies for enrichment and selection of stem cell-derived tissue precursors
    Harold S Bernstein
    Department of Pediatrics Cardiology, University of California San Francisco, San Francisco, CA 94143 1346, USA
    Stem Cell Res Ther 3:17. 2012
  6. doi request reprint Stem cell therapy for cardiac disease
    Harold S Bernstein
    Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA
    Pediatr Res 71:491-9. 2012
  7. pmc Labeling human embryonic stem cell-derived cardiomyocytes with indocyanine green for noninvasive tracking with optical imaging: an FDA-compatible alternative to firefly luciferase
    Sophie E Boddington
    Department of Radiology, University of California, San Francisco, CA 94107 0946, USA
    Cell Transplant 19:55-65. 2010

Research Grants

  1. CELL CYCLE REGULATION IN CARDIOVASCULAR BIOLOGY
    HAROLD BERNSTEIN; Fiscal Year: 2003
  2. Training in Developmental Cardiovascular Biology
    HAROLD BERNSTEIN; Fiscal Year: 2007
  3. Stem Cell Differentiation for Myocardial Therapy
    HAROLD BERNSTEIN; Fiscal Year: 2007

Collaborators

Detail Information

Publications9

  1. pmc An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors
    Carissa Ritner
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e16004. 2011
    ..The identification of hMPs using this αMHC-GFP reporter line will provide important insight into the pathways regulating human myocardial development, and may provide a novel therapeutic reagent for the treatment of cardiac disease...
  2. pmc The promise of human embryonic stem cells in aging-associated diseases
    Odessa Yabut
    Cardiovascular Research Institute, San Francisco, CA 94143, USA
    Aging (Albany NY) 3:494-508. 2011
    ..Finally, we will highlight the general challenges that must be overcome and the strategies being developed to generate highly-purified hESC-derived cell populations that can safely be used for clinical applications...
  3. pmc miR-125b promotes early germ layer specification through Lin28/let-7d and preferential differentiation of mesoderm in human embryonic stem cells
    Sharon S Y Wong
    Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e36121. 2012
    ..Manipulation of miR-125b-mediated pathways may provide a novel approach to directing the differentiation of hESC-derived CMs for cell therapy applications...
  4. doi request reprint Cardiac repair and restoration using human embryonic stem cells
    Harold S Bernstein
    Department of Pediatrics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143 1346, USA
    Regen Med 7:697-712. 2012
    ....
  5. pmc Strategies for enrichment and selection of stem cell-derived tissue precursors
    Harold S Bernstein
    Department of Pediatrics Cardiology, University of California San Francisco, San Francisco, CA 94143 1346, USA
    Stem Cell Res Ther 3:17. 2012
    ..Finally, we will describe the next generation of methods being developed to identify and select stem cell-derived tissue precursors for experimental study and clinical use...
  6. doi request reprint Stem cell therapy for cardiac disease
    Harold S Bernstein
    Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA
    Pediatr Res 71:491-9. 2012
    ..Finally, we will review progress being made in assessing functional improvement in animals and humans after cellular transplant...
  7. pmc Labeling human embryonic stem cell-derived cardiomyocytes with indocyanine green for noninvasive tracking with optical imaging: an FDA-compatible alternative to firefly luciferase
    Sophie E Boddington
    Department of Radiology, University of California, San Francisco, CA 94107 0946, USA
    Cell Transplant 19:55-65. 2010
    ..The technique may be useful for assessing different delivery routes in order to improve the engraftment of transplanted hESC-CMs or other stem cell progenitors...

Research Grants9

  1. CELL CYCLE REGULATION IN CARDIOVASCULAR BIOLOGY
    HAROLD BERNSTEIN; Fiscal Year: 2003
    ..These studies will provide basic insights into transcriptional mechanisms for G2/M control as well as reagents for manipulating the cell cycle in non-dividing tissues. ..
  2. Training in Developmental Cardiovascular Biology
    HAROLD BERNSTEIN; Fiscal Year: 2007
    ..Each trainee will execute a research project with one of the 25 outstanding program faculty preceptors. ..
  3. Stem Cell Differentiation for Myocardial Therapy
    HAROLD BERNSTEIN; Fiscal Year: 2007
    ..The proposed studies will provide new insight into human cardiac myogenesis, and offer novel approaches to myocardial regeneration. ..