David Bernstein

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. pmc Diesel exhaust exposure, wheezing and sneezing
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Allergy Asthma Immunol Res 4:178-83. 2012
  2. pmc CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Toxicol Sci 131:242-6. 2013
  3. doi request reprint Effects of intranasal mometasone furoate on itchy ear and palate in patients with seasonal allergic rhinitis
    David I Bernstein
    Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, 3255 Eden Ave, Cincinnati, OH 45267 0563, USA
    Ann Allergy Asthma Immunol 108:359-62. 2012
  4. pmc Efficacy and onset of action of mometasone furoate/formoterol and fluticasone propionate/salmeterol combination treatment in subjects with persistent asthma
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Allergy Asthma Clin Immunol 7:21. 2011
  5. doi request reprint Traffic-related pollutants and wheezing in children
    David I Bernstein
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0563, USA
    J Asthma 49:5-7. 2012
  6. doi request reprint Genetics of occupational asthma
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Curr Opin Allergy Clin Immunol 11:86-9. 2011
  7. doi request reprint Surveillance of systemic reactions to subcutaneous immunotherapy injections: year 1 outcomes of the ACAAI and AAAAI collaborative study
    David I Bernstein
    Department of Medicine, Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 104:530-5. 2010
  8. ncbi request reprint Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis
    D I Bernstein
    Division of Immunology Allergy and Bernstein Clinical Research Center, Inc, University of Cincinnati, Cincinnati, OH 45267, USA
    Clin Exp Allergy 34:952-7. 2004
  9. doi request reprint Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort
    Heidi Sucharew
    Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH 45267 0056, USA
    Pediatr Allergy Immunol 21:253-9. 2010
  10. pmc House dust bioactivities predict skin prick test reactivity for children with high risk of allergy
    Haejin Kim
    Department of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    J Allergy Clin Immunol 129:1529-37.e2. 2012

Research Grants

Detail Information

Publications83

  1. pmc Diesel exhaust exposure, wheezing and sneezing
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Allergy Asthma Immunol Res 4:178-83. 2012
    ..High ECAT was significantly associated with wheezing at age 1 as well as persistent wheezing at age 3. High mold exposure predicted a well defined asthma phenotype at age 7...
  2. pmc CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Toxicol Sci 131:242-6. 2013
    ..These findings lend further support to the clinical relevance of these genotypes in predicting susceptibility to DA and the potential importance of catenins in the disease process...
  3. doi request reprint Effects of intranasal mometasone furoate on itchy ear and palate in patients with seasonal allergic rhinitis
    David I Bernstein
    Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, 3255 Eden Ave, Cincinnati, OH 45267 0563, USA
    Ann Allergy Asthma Immunol 108:359-62. 2012
    ..Intranasal steroids relieve nasal symptoms and ocular itch in allergic rhinitis. Itchy ear and palate are also common and bothersome symptoms but have received little attention in clinical trials of allergic rhinitis...
  4. pmc Efficacy and onset of action of mometasone furoate/formoterol and fluticasone propionate/salmeterol combination treatment in subjects with persistent asthma
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Allergy Asthma Clin Immunol 7:21. 2011
    ..abstract:..
  5. doi request reprint Traffic-related pollutants and wheezing in children
    David I Bernstein
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0563, USA
    J Asthma 49:5-7. 2012
    ....
  6. doi request reprint Genetics of occupational asthma
    David I Bernstein
    Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Curr Opin Allergy Clin Immunol 11:86-9. 2011
    ..To discuss gene association studies conducted in workers diagnosed with occupational asthma...
  7. doi request reprint Surveillance of systemic reactions to subcutaneous immunotherapy injections: year 1 outcomes of the ACAAI and AAAAI collaborative study
    David I Bernstein
    Department of Medicine, Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 104:530-5. 2010
    ..Although systemic reactions (SRs) to subcutaneous immunotherapy (SCIT) injections are not uncommon, life-threatening and fatal reactions are rare. The annual incidence of injection-related SRs of varying severity is not well-defined...
  8. ncbi request reprint Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis
    D I Bernstein
    Division of Immunology Allergy and Bernstein Clinical Research Center, Inc, University of Cincinnati, Cincinnati, OH 45267, USA
    Clin Exp Allergy 34:952-7. 2004
    ..If monotherapy with an intranasal corticosteroid can alleviate both nasal and ocular symptoms of allergic rhinitis, treatment may be simplified and costs may be reduced...
  9. doi request reprint Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort
    Heidi Sucharew
    Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH 45267 0056, USA
    Pediatr Allergy Immunol 21:253-9. 2010
    ..73, 95% CI: 0.53, 1.01). No other factors were significant. These results suggest that traffic exhaust exposure may be a risk factor for night cough in young children...
  10. pmc House dust bioactivities predict skin prick test reactivity for children with high risk of allergy
    Haejin Kim
    Department of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    J Allergy Clin Immunol 129:1529-37.e2. 2012
    ....
  11. ncbi request reprint Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes
    David I Bernstein
    Department of Internal Medicine, Division of Immunology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Ann Allergy Asthma Immunol 97:800-6. 2006
    ..Diisocyanate asthma (DA) affects 2% to 10% of exposed workers, yet the pathogenetic mechanisms underlying this disorder remain ill defined...
  12. pmc Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of age
    Nicholas C Newman
    Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Environ Health Perspect 121:731-6. 2013
    ..There is increasing concern about the potential effects of traffic-related air pollution (TRAP) on the developing brain. The impact of TRAP exposure on childhood behavior is not fully understood because of limited epidemiologic studies...
  13. doi request reprint Occupational rhinitis
    J Wesley Sublett
    Division of Immunology Allergy Section, Department of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML 563, Cincinnati, OH 45267 0563, USA
    Curr Allergy Asthma Rep 10:99-104. 2010
    ..If treatment allergens are commercially available, allergen immunotherapy may also be considered if appropriate...
  14. pmc Influence of dog ownership and high endotoxin on wheezing and atopy during infancy
    Paloma Campo
    Department of Internal Medicine, Immunology Division, University of Cincinnati, Cincinnati, OH 45267 0563, USA
    J Allergy Clin Immunol 118:1271-8. 2006
    ..Increased exposure to microbial products early in life may protect from development of atopic disorders in childhood. Few studies have examined the relationship of endotoxin exposure and pet ownership on atopy and wheezing during infancy...
  15. pmc Predicting allergic disease at age four using an atopy predisposition score at age two: the application of item response theory
    Heidi Sucharew
    Division of Biostatistics and Epidemiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    Pediatr Allergy Immunol 23:195-201. 2012
    ..The IRT model proved to be an informative methodology to assess the predictability of early SPT responses and identify the allergens most associated with atopy predisposition...
  16. pmc Mold damage in homes and wheezing in infants
    Seung Hyun Cho
    Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
    Ann Allergy Asthma Immunol 97:539-45. 2006
    ..In most studies that investigate the association of mold or water damage and respiratory disorders in infants, the analysis is not adjusted for exposure to house dust mite (HDM), which is also a known cause of respiratory illnesses...
  17. ncbi request reprint Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determinants of childhood allergic rhinitis
    Christopher D Codispoti
    Department of Internal Medicine, Division of Immunology, Allergy and Rheumatology, University of Cincinnati, Cincinnati, Ohio 4267 0563, USA
    J Allergy Clin Immunol 125:1054-1060.e1. 2010
    ..Infant predictors of early childhood allergic rhinitis (AR) are poorly understood...
  18. ncbi request reprint Evaluation of antibody binding to diisocyanate protein conjugates in a general population
    David I Bernstein
    Division of Immunology and Allergy, University of Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 97:357-64. 2006
    ..Because comparable assays were not performed using individuals distant from such facilities, the significance of this finding is uncertain...
  19. pmc Associations between multiple environmental exposures and Glutathione S-Transferase P1 on persistent wheezing in a birth cohort
    Kathy T Schroer
    Division of Asthma Research, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    J Pediatr 154:401-8, 408.e1. 2009
    ....
  20. pmc Atopy as a risk factor for habitual snoring at age 1 year
    Maninder Kalra
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
    Chest 129:942-6. 2006
    ..To determine the prevalence of habitual snoring (HS) in 1-year-old children, and to assess the relationship between HS and atopic status in these children...
  21. ncbi request reprint Allergy diagnostic testing: an updated practice parameter
    I Leonard Bernstein
    University of Cincinnati College of Medicine, Ohio, USA
    Ann Allergy Asthma Immunol 100:S1-148. 2008
  22. pmc Environmental risk factors of rhinitis in early infancy
    Jocelyn M Biagini
    Department of Environmental Health, University of Cincinnati, and Division of Allergy and Immunology, Department of Pediatrics, Cincinati Children s Hospital Medical Center, OH 45267 0056, USA
    Pediatr Allergy Immunol 17:278-84. 2006
    ..This study suggests that ETS exposure, rather than visible mold, is associated with rhinitis and allergic rhinitis in infants. The analysis also suggests that mold may be a stronger risk factor for URI that ETS...
  23. pmc Specific fungal exposures, allergic sensitization, and rhinitis in infants
    Melissa Osborne
    Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA
    Pediatr Allergy Immunol 17:450-7. 2006
    ..05), and Cladosporium and SPT(+) to aeroallergens (p < 0.05). This study indicates that health outcome may vary by fungal genera; some fungal types may have sensitizing effects while others may have a beneficial role...
  24. pmc High prevalence of aeroallergen sensitization among infants of atopic parents
    Grace K LeMasters
    Department of Environmental Health, Division of Epidemiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Pediatr 149:505-11. 2006
    ..To present methodology to identify atopic parents and determine the prevalence of sensitization to 15 aeroallergens in their infant offspring...
  25. pmc A comparison of proximity and land use regression traffic exposure models and wheezing in infants
    Patrick H Ryan
    Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA
    Environ Health Perspect 115:278-84. 2007
    ..We previously reported an association between infant wheezing and residence < 100 m from stop-and-go bus and truck traffic. The use of a proximity model, however, may lead to exposure misclassification...
  26. doi request reprint Management of work-related asthma
    Andrew M Smith
    Division of Immunology, Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    J Allergy Clin Immunol 123:551-7. 2009
    ..Although allergen immunotherapy has a putative role in treating and preventing WRA caused by HMW sensitizers, further study is needed...
  27. ncbi request reprint ABCs of Asthma
    David I Bernstein
    Department of Internal Medicine, Division of Immunology and Allergy, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Clin Cornerstone 8:9-25. 2008
    ..Physicians and providers should continually educate asthmatic patients about proper use of asthma controller medications, avoidance of asthma triggers, and self-management of asthma exacerbations...
  28. doi request reprint Environmental tobacco smoke and interleukin 4 polymorphism (C-589T) gene: environment interaction increases risk of wheezing in African-American infants
    Andrew M Smith
    Department of Internal Medicine, Division of Immunology, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    J Pediatr 152:709-15, 715.e1. 2008
    ..To determine whether infants exposed to environmental tobacco smoke (ETS) having the interleukin 4 (IL-4) or interleukin 13 (IL-13) gene polymorphisms were at increased risk of wheezing...
  29. pmc Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years
    Patrick H Ryan
    Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Am J Respir Crit Care Med 180:1068-75. 2009
    ..Murine models demonstrate a synergistic production of reactive oxygen species on coexposure to diesel exhaust particles and endotoxin...
  30. pmc Acellular pertussis vaccines and complement killing of Bordetella pertussis
    Alison A Weiss
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0524, USA
    Infect Immun 72:7346-51. 2004
    ..The responses of the other individuals were complex, with evidence of both beneficial and antagonistic responses occurring, sometimes in the same individual...
  31. ncbi request reprint Advances in methods used in evaluation of occupational asthma
    Paloma Campo
    Division of Immunology Allergy, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Curr Opin Pulm Med 10:142-6. 2004
    ..Recent development or refinement of diagnostic tools may improve the diagnostic accuracy, which may have important economic and social consequences for both employers and workers...
  32. ncbi request reprint Diisocyanate antigen-stimulated monocyte chemoattractant protein-1 synthesis has greater test efficiency than specific antibodies for identification of diisocyanate asthma
    David I Bernstein
    Department of Internal Medicine, Division of Immunology, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0563, USA
    Am J Respir Crit Care Med 166:445-50. 2002
    ..This study indicates that the MCP-1 stimulation assay has greater sensitivity and specificity than the specific antibody assays in correctly identifying DA...
  33. ncbi request reprint Clinical and occupational outcomes in health care workers with natural rubber latex allergy
    David I Bernstein
    University of Cincinnati College of Medicine, Division of Immunology, Department of Internal Medicine, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 90:209-13. 2003
    ..There is limited information pertaining to clinical outcomes and economic consequences of natural rubber latex (NRL) allergy in health care workers (HCWs)...
  34. ncbi request reprint In vivo sensitization to purified Hevea brasiliensis proteins in health care workers sensitized to natural rubber latex
    David I Bernstein
    University of Cincinnati College of Medicine, Ohio, USA
    J Allergy Clin Immunol 111:610-6. 2003
    ..However, the in vivo importance of native Hev b allergens has not been defined in health care workers (HCWs) with natural rubber latex (NRL) allergy...
  35. ncbi request reprint Occupational asthma caused by exposure to low-molecular-weight chemicals
    David I Bernstein
    Division of Immunology and Allergy, Department of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0563, USA
    Immunol Allergy Clin North Am 23:221-34, vi. 2003
    ..An early diagnosis followed by cessation of exposure can result in asthma remission and is likely to prevent progression to chronic disabling obstructive disease...
  36. doi request reprint Mold exposure during infancy as a predictor of potential asthma development
    Yulia Y Iossifova
    Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio 45267 0056, USA
    Ann Allergy Asthma Immunol 102:131-7. 2009
    ..Exposure to mold has been associated with exacerbation of asthma symptoms in children...
  37. pmc The effect of home characteristics on dust antigen concentrations and loads in homes
    Seung Hyun Cho
    Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
    Sci Total Environ 371:31-43. 2006
    ..This study encompassed a wide range of home characteristics and various antigen types. Our findings provide information on home characteristics that can be used for allergen avoidance and in planning future exposure assessment studies...
  38. pmc Genetic and environmental risk factors for childhood eczema development and allergic sensitization in the CCAAPS cohort
    Jocelyn M Biagini Myers
    Division of Asthma Research, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Invest Dermatol 130:430-7. 2010
    ..The results also demonstrate a susceptibility effect of the combination of CD14 and IL4Ralpha SNPs with eczema...
  39. ncbi request reprint Management of natural rubber latex allergy
    David I Bernstein
    Division of Immunology, University of Cincinnati, OH 45267 0563, USA
    J Allergy Clin Immunol 110:S111-6. 2002
    ....
  40. doi request reprint A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
    Sally E Wenzel
    Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Am J Respir Crit Care Med 179:549-58. 2009
    ..The treatment effect of golimumab, a human monoclonal antibody against tumor necrosis factor (TNF)-alpha, in severe persistent asthma is unknown...
  41. ncbi request reprint Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic
    Patrick H Ryan
    Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267 0056, USA
    J Allergy Clin Immunol 116:279-84. 2005
    ..Previous studies of air pollution have not examined the association between exposure to varying types, distance, and amounts of traffic and wheezing in very young infants...
  42. ncbi request reprint Anaphylactic reactions during immunotherapy
    Maziar Rezvani
    Division of Allergy Immunology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0563, USA
    Immunol Allergy Clin North Am 27:295-307, viii. 2007
    ..As with any treatment, anticipated benefits attributed to IT must be weighed against its potential risks...
  43. doi request reprint The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: effectiveness of early intervention with budesonide in mild persistent asthma
    William W Busse
    Department of Medicine, University of Wisconsin School of Medicine and Public Health, J5 219 CSC, Box 2454, 600 Highland Ave, Madison, WI 53792, USA
    J Allergy Clin Immunol 121:1167-74. 2008
    ....
  44. ncbi request reprint Twelve-year survey of fatal reactions to allergen injections and skin testing: 1990-2001
    David I Bernstein
    Division of Immunology Allergy, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0563, USA
    J Allergy Clin Immunol 113:1129-36. 2004
    ..Fatal reactions associated with skin testing and injection immunotherapy have not been surveyed in North America since 1989...
  45. ncbi request reprint Evaluation of near-fatal reactions to allergen immunotherapy injections
    Hetal S Amin
    Department of Internal Medicine, Division of Immunology and Allergy, University of Cincinnati, Cincinnati, OH 45267, USA
    J Allergy Clin Immunol 117:169-75. 2006
    ..The overall incidence of near-fatal reactions (NFRs) after immunotherapy injections is unknown. Investigation of NFRs might identify preventive strategies that could avert fatal immunotherapy reactions...
  46. ncbi request reprint Key pollen allergens in North America
    Jason F White
    University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 91:425-35; quiz 435-6, 492. 2003
    ..To discuss major pollen aeroallergens in North America that are essential for effective immunotherapy and to propose a list of pollen aeroallergens that could be prioritized for allergen standardization...
  47. ncbi request reprint Lack of correlation between regional pollen counts and percutaneous reactivity to tree pollen extracts in patients with seasonal allergic rhinitis
    Jason F White
    Division of Immunology Allergy, Department of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 94:240-6. 2005
    ..Although seasonal patterns of tree pollination have been reported, it is unknown if aerobiologic data correlate with patterns of in vivo sensitization...
  48. ncbi request reprint Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force
    Linda Cox
    Department of Medicine, Nova Southeaster University Osteopathic College of Medicine, Davie, Florida 33334, USA
    Ann Allergy Asthma Immunol 101:580-92. 2008
    ....
  49. ncbi request reprint Safety, efficacy, and immunogenicity of a live, quadrivalent human-bovine reassortant rotavirus vaccine in healthy infants
    H Fred Clark
    University of Pennsylvania School of Medicine, Philadelphia, and Merck and Co, Inc, West Point, Pennsylvania 19486, USA
    J Pediatr 144:184-90. 2004
    ..To investigate safety, efficacy, and immunogenicity of live quadrivalent rotavirus vaccine (QRV) containing human-bovine (WC3) reassortant rotavirus serotypes G1, G2, G3, and P1a...
  50. ncbi request reprint Evaluation of tests of hypothalamic-pituitary-adrenal axis function used to measure effects of inhaled corticosteroids
    David I Bernstein
    Department of Internal Medicine, Division of Immunology Allergy, University of Cincinnati, Cincinnati, Ohio 45267 0563, USA
    Ann Allergy Asthma Immunol 98:118-27. 2007
    ....
  51. pmc Antibody-mediated neutralization of pertussis toxin-induced mitogenicity of human peripheral blood mononuclear cells
    Scott H Millen
    Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    Infect Immun 72:615-20. 2004
    ..the convalescent group had higher titers in the PBMC assay. Results for pertussis toxin neutralization with the CHO assay appear to be distinct from those with the PBMC assay...
  52. ncbi request reprint Rapid venom immunotherapy update
    Troy A Scribner
    Cincinnati Children s Hospital, Division of Allergy and Medical Center, Cincinnati, Ohio 45267, USA
    Curr Opin Allergy Clin Immunol 3:295-8. 2003
    ..This paper will review new indications for the administration of rapid or ultrarush venom immunotherapy and the advantages of pretreatment with antihistamines...
  53. ncbi request reprint A phase 1 study of 4 live, recombinant human cytomegalovirus Towne/Toledo chimeric vaccines
    Thomas C Heineman
    Division of Infectious Diseases and Immunology, Saint Louis University School of Medicine, St Louis, Missouri 63110, and Division of Pediatric Infectious Diseases, Children s Hospital Medical Center, University of Cincinnati, OH, USA
    J Infect Dis 193:1350-60. 2006
    ..Although not evaluated for this indication, live attenuated HCMV vaccines based on the Towne strain are well-tolerated and have demonstrated moderate efficacy in other clinical settings...
  54. pmc Quantitative PCR analysis of house dust can reveal abnormal mold conditions
    Teija Meklin
    National Exposure Research Laboratory, US Environmental Protection Agency, Cincinnati, OH 45268, USA
    J Environ Monit 6:615-20. 2004
    ..Culturing underestimated the concentrations of these four species by 2 to 3 orders of magnitude compared to QPCR...
  55. ncbi request reprint Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers
    David I Bernstein
    Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 44259, USA
    Vaccine 28:484-93. 2009
    ..This alphavirus replicon particle vaccine was safe and induced neutralizing antibody and multifunctional T cell responses against three CMV antigens that are important targets for protective immunity...
  56. pmc Potent adjuvant activity of cationic liposome-DNA complexes for genital herpes vaccines
    David I Bernstein
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Clin Vaccine Immunol 16:699-705. 2009
    ..CLDC appears to be a potent adjuvant for HSV vaccines and should be evaluated further...
  57. ncbi request reprint Live attenuated human rotavirus vaccine, Rotarix
    David I Bernstein
    Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, OH 45229, USA
    Semin Pediatr Infect Dis 17:188-94. 2006
    ..Efficacy against severe rotavirus gastroenteritis and hospitalization have ranged from 85 to 100 percent...
  58. ncbi request reprint Psychological, behavioral, and interpersonal impact of human papillomavirus and Pap test results
    Jessica A Kahn
    Division of Adolescent Medicine, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    J Womens Health (Larchmt) 14:650-9. 2005
    ..The purpose of this study was to explore the short-term psychological, behavioral, and interpersonal impact of human papillomavirus (HPV) and Pap results in adolescent and young adult women...
  59. pmc Relative moldiness index as predictor of childhood respiratory illness
    Stephen J Vesper
    US Environmental Protection Agency, Cincinnati, OH, USA
    J Expo Sci Environ Epidemiol 17:88-94. 2007
    ..27). Conversely, a method developed and validated in this paper, using the RMI index fit to a logistic function, can be used to predict the occurrence of illness in homes and allows stake-holders the choice among various levels of risk...
  60. ncbi request reprint Prevalence of diarrheagenic Escherichia coli in acute childhood enteritis: a prospective controlled study
    Mitchell B Cohen
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    J Pediatr 146:54-61. 2005
    ..Since diarrheagenic E. coli are not identified by common clinical laboratory techniques, we hypothesized that these organisms might be an unrecognized cause of enteritis in children in the U.S...
  61. ncbi request reprint Evaluation of the clinical efficacy and safety of grapeseed extract in the treatment of fall seasonal allergic rhinitis: a pilot study
    David I Bernstein
    Division of Immunology, University of Cincinnati College of Medicine, Ohio 45267, USA
    Ann Allergy Asthma Immunol 88:272-8. 2002
    ..Although grapeseed extract (GSE) is an herbal that is marketed for treating allergic rhinitis, its efficacy is unproven...
  62. ncbi request reprint Second-year follow-up evaluation of live, attenuated human rotavirus vaccine 89-12 in healthy infants
    David I Bernstein
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    J Infect Dis 186:1487-9. 2002
    ..001 for each). These encouraging results have led to continued evaluation, in several countries, of a vaccine candidate derived from strain 89-12...
  63. ncbi request reprint Clinical presentations of rotavirus infection among hospitalized children
    Mary Allen Staat
    Division of Infectious Disease, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Pediatr Infect Dis J 21:221-7. 2002
    ..Although rotaviruses (RVs) are the most common cause of severe gastroenteritis in children, there is a lack of information detailing the spectrum of clinical manifestations of RV disease resulting in hospitalization...
  64. ncbi request reprint Rotavirus overview
    David I Bernstein
    Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA
    Pediatr Infect Dis J 28:S50-3. 2009
    ..Rotavirus vaccination is now included as part of the routine vaccination schedule for all infants in the United States...
  65. ncbi request reprint Predictors of herpes simplex virus type 2 antibody positivity among persons with no history of genital herpes
    Kenneth H Fife
    Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Sex Transm Dis 31:676-81. 2004
    ..The demographic, historical, and behavioral factors that predict a positive herpes simplex virus type 2 (HSV-2) antibody test in persons without a history of genital herpes have not been well-defined...
  66. doi request reprint Effects of adjuvants on the safety and immunogenicity of an avian influenza H5N1 vaccine in adults
    David I Bernstein
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Infect Dis 197:667-75. 2008
    ..Influenza A H5N1 viruses pose a significant threat to human health...
  67. ncbi request reprint Rotavirus immunoglobulin a responses stimulated by each of 3 doses of a quadrivalent human/bovine reassortant rotavirus vaccine
    Richard L Ward
    Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Infect Dis 189:2290-3. 2004
    ..In total, 16, 19, and 15 vaccine recipients had increases after 1, 2, and 3 doses, respectively, indicating that a 3-dose regimen increased the immune response elicited by this vaccine...
  68. ncbi request reprint Rhesus rotavirus vaccine effectiveness and factors associated with receipt of vaccine
    Mary Allen Staat
    Cincinnati Children s Hospital Medical Center, Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Pediatr Infect Dis J 25:1013-8. 2006
    ..The objective of this study was to determine the effectiveness of the RotaShield vaccine against rotavirus gastroenteritis requiring hospitalization and to evaluate factors associated with vaccine receipt...
  69. ncbi request reprint A case-control study to determine risk factors for hospitalization for rotavirus gastroenteritis in U.S. children
    Penelope H Dennehy
    Hasbro Children s Hospital and Brown Medical School, Department of Pediatrics, Division of Infectious Diseases, Providence, RI 02903
    Pediatr Infect Dis J 25:1123-31. 2006
    ....
  70. ncbi request reprint Efficacy of an acellular pertussis vaccine among adolescents and adults
    Joel I Ward
    UCLA Center for Vaccine Research, Research and Education Institute, Harbor UCLA Medical Center, David Geffen School of Medicine, UCLA, Torrance, Calif 90502, USA
    N Engl J Med 353:1555-63. 2005
    ..This trial of an acellular pertussis vaccine among adolescents and adults evaluated the incidence of pertussis, vaccine safety, immunogenicity, and protective efficacy...
  71. ncbi request reprint Bordetella Pertussis infections in vaccinated and unvaccinated adolescents and adults, as assessed in a national prospective randomized Acellular Pertussis Vaccine Trial (APERT)
    Joel I Ward
    University of California Los Angeles UCLA Center for Vaccine Research, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, David Geffen School of Medicine UCLA, Torrance, California 90502 2502, USA
    Clin Infect Dis 43:151-7. 2006
    ..Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term protection and to possibly reduce community transmission of infections...
  72. ncbi request reprint Evaluation of imiquimod 5% cream to modify the natural history of herpes labialis: a pilot study
    David I Bernstein
    Children s Hospital Medical Center Division of Infectious Diseases, Cincinnati, OH 45229, USA
    Clin Infect Dis 41:808-14. 2005
    ..Therefore, we evaluated the safety and potential of topical imiquimod to decrease the rate of recurrence in humans with a history of recurrent herpes labialis...
  73. ncbi request reprint Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 95:600-6. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
  74. ncbi request reprint Safety of the trivalent, cold-adapted influenza vaccine in preschool-aged children
    Pedro A Piedra
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
    Pediatrics 110:662-72. 2002
    ..To provide additional information on the safety of trivalent, cold-adapted influenza vaccine (CAIV-T) in children...
  75. ncbi request reprint Safety and immunogenicity of concurrent administration of live attenuated influenza vaccine with measles-mumps-rubella and varicella vaccines to infants 12 to 15 months of age
    Terry Nolan
    School of Population Health, University of Melbourne and Murdoch Children s Research Institute, Carlton, Melbourne, Victoria 3010, Australia
    Pediatrics 121:508-16. 2008
    ..This study evaluated the safety, tolerability, and immunogenicity of live attenuated influenza vaccine administered concurrently with measles-mumps-rubella vaccine and varicella vaccine to healthy children 12 to 15 months of age...
  76. ncbi request reprint Glycoprotein-D-adjuvant vaccine to prevent genital herpes
    Lawrence R Stanberry
    Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston 77555 0351, USA
    N Engl J Med 347:1652-61. 2002
    ..An effective prophylactic vaccine would help control the spread of genital herpes...
  77. ncbi request reprint Transmissibility, infectivity and immunogenicity of a live human parainfluenza type 3 virus vaccine (HPIV3cp45) among susceptible infants and toddlers
    Shabir A Madhi
    University of the Witwatersrand Medical Research Council Respiratory and Meningeal Pathogens Research Unit, South Africa
    Vaccine 24:2432-9. 2006
    ..This study examined the transmissibility between young children of an intranasally administered live attenuated human parainfluenza virus type 3 (HPIV3)-cp45 vaccine candidate...
  78. ncbi request reprint Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial
    Thomas R Talbot
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA s
    JAMA 292:1205-12. 2004
    ....
  79. ncbi request reprint Factors predicting the acceptance of herpes simplex virus type 2 antibody testing among adolescents and young adults
    Gregory D Zimet
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA
    Sex Transm Dis 31:665-9. 2004
    ..The rates and determinants of acceptance of herpes simplex virus type 2 (HSV-2) testing have not been adequately studied...
  80. doi request reprint The diagnosis and management of rhinitis: an updated practice parameter
    Dana V Wallace
    J Allergy Clin Immunol 122:S1-84. 2008
  81. ncbi request reprint Use of active surveillance to validate international classification of diseases code estimates of rotavirus hospitalizations in children
    Vincent P Hsu
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Pediatrics 115:78-82. 2005
    ..Our study evaluated the sensitivity of the rotavirus ICD code among children hospitalized for AGE by using active surveillance for rotavirus at a tertiary children's hospital...
  82. ncbi request reprint The skin prick test: "more than meets the eye"
    David I Bernstein
    Ann Allergy Asthma Immunol 92:587-8. 2004
  83. ncbi request reprint Predictors of sexual satisfaction in an adolescent and college population
    Beth A Auslander
    Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX 77555 0319, USA
    J Pediatr Adolesc Gynecol 20:25-8. 2007
    ..To assess the degree to which adolescents/young adults are satisfied in their current sexual relationships and to evaluate intrapersonal and interpersonal predictors of sexual satisfaction among that population...

Research Grants10

  1. CHEMOKINE BIOMARKERS OF DIISOCYANATE OCCUPATIONAL ASTHMA
    David Bernstein; Fiscal Year: 1999
    ..abstract_text> ..
  2. Genetics Susceptibility for Occupational Asthma
    David Bernstein; Fiscal Year: 2007
    ....
  3. Immunology / Allergy Fellowship Training Grant
    David Bernstein; Fiscal Year: 2007
    ..Future recruitment of fellows to this program will require selection of the most highly qualified physician candidates with particular attention to recruitment of minorities and women who fulfill these requirements. ..
  4. Genetics Susceptibility for Occupational Asthma
    David Bernstein; Fiscal Year: 2006
    ....
  5. CHEMOKINE BIOMARKERS OF DIISOCYANATE OCCUPATIONAL ASTHMA
    David Bernstein; Fiscal Year: 2002
    ..abstract_text> ..
  6. CHEMOKINE BIOMARKERS OF DIISOCYANATE OCCUPATIONAL ASTHMA
    David Bernstein; Fiscal Year: 2001
    ..abstract_text> ..
  7. CHEMOKINE BIOMARKERS OF DIISOCYANATE OCCUPATIONAL ASTHMA
    David Bernstein; Fiscal Year: 2000
    ..abstract_text> ..
  8. Genetics Susceptibility for Occupational Asthma
    David Bernstein; Fiscal Year: 2009
    ....