Research Topics
| Jeffrey S BernsSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
That catheter is going to cost you!Jeffrey S Berns
Renal-Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 19:440-2. 2006
Performance of procedures by nephrologists and nephrology fellows at U.S. nephrology training programsJeffrey S Berns
University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 1 Founders Pavilion, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 3:941-7. 2008..To assess the procedures performed by nephrologists and nephrology fellows at U.S. adult nephrology training programs and the number of procedures required for fellow competency, a survey was conducted of all such training programs...
Viruses and diseases of the kidneysJeffrey S Berns
The Renal-Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Clin J Am Soc Nephrol 2:S1. 2007
The effect of a change in epoetin alfa reimbursement policy on anemia outcomes in hemodialysis patientsJeffrey S Berns
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19146, USA
Hemodial Int 9:255-63. 2005..The decline in mean weekly dose of epoetin was likely a result of withholding doses out of concern among providers about risk of reimbursement denial...
Pharmacologic adjuvants to epoetin in the treatment of anemia in patients on hemodialysisJeffrey S Berns
Department of Medicine Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Presbyterian Medical Center, 51 N 39th Street, Medical Office Building No 240, Philadelphia, PA 19104, U S A
Hemodial Int 9:7-22. 2005..A review of published guidelines and recommendations for use of these agents in hemodialysis patients is provided...
A survey-based evaluation of self-perceived competency after nephrology fellowship trainingJeffrey S Berns
University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 1 Founders Pavilion, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 5:490-6. 2010..There have been no recent analyses of the adequacy of training in U.S. nephrology training programs or the importance of specific aspects of fellowship training in the careers and practices of nephrologists who recently completed training...
Are there implications from the Trial to Reduce Cardiovascular Events with Aranesp Therapy study for anemia management in dialysis patients?Jeffrey S Berns
University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Curr Opin Nephrol Hypertens 19:567-72. 2010..This review addresses this and other recent studies of ESA treatment for renal anemia to higher hemoglobin (Hgb) targets above the range of 10-12 g/dl...
Should the target hemoglobin for patients with chronic kidney disease treated with erythropoietic replacement therapy be changed?Jeffrey S Berns
Department of Medicine, Renal, Electrolyte, Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 191041, USA
Semin Dial 18:22-9. 2005..Future efforts are likely to focus on selecting patient populations most likely to benefit from normalizing Hb, while adjusting the range of a subnormal Hb target for others...
Preventing bacterial infections and antimicrobial resistance in dialysis patientsJeffrey S Berns
University of Pennsylvania School of Medicine, Presbyterian Medical Center, Philadelphia, PA 19104, USA
Am J Kidney Dis 40:886-98. 2002..Fourth, preventing transmission in health care settings is important to limit the spread of resistant organisms. In this regard, such basic measures as glove use and hand hygiene are most important...
Infection with antimicrobial-resistant microorganisms in dialysis patientsJeffrey S Berns
Department of Medicine, Renal, Electrolyte, and Hypertension Division, University of Pennsylvania School of Medicine and Presbyterian Medical Center, Philadelphia, Pennsylvania 19104, USA
Semin Dial 16:30-7. 2003..Preventing transmission of antimicrobial-resistant microorganisms in health care settings, including outpatient dialysis facilities, is important in limiting the spread of these resistant organisms...
Highly active antiretroviral therapy and the kidney: an update on antiretroviral medications for nephrologistsJeffrey S Berns
Renal, Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine, Penn Presbyterian Medical Center, 51 N 39th Street, Medical Office Building 240, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 1:117-29. 2006....
Hemoglobin variability in epoetin-treated hemodialysis patientsJeffrey S Berns
Renal, Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Kidney Int 64:1514-21. 2003..This study examines hemoglobin variability under conditions of standard clinical practice in epoetin-treated hemodialysis patients...
History-adjusted marginal structural analysis of the association between hemoglobin variability and mortality among chronic hemodialysis patientsSteven M Brunelli
Renal, Electrolyte and Hypertension Division of the Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Clin J Am Soc Nephrol 3:777-82. 2008..The causal nature of this association has been difficult to ascertain because of potential time-dependent confounding, for which traditional statistical methods do not control...
Staphylococcus-infected tunneled dialysis catheters: is over-the-wire exchange an appropriate management option?Jessica M Langer
Division of Interventional Radiology, Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Cardiovasc Intervent Radiol 34:1230-5. 2011..This study addressed the effectiveness of over-the-wire exchange of staphylococcus-infected tunneled dialysis catheters compared with non-staphylococcus-infected tunneled dialysis catheters...
Anemia and mortality in hemodialysis patients: accounting for morbidity and treatment variables updated over timeBruce M Robinson
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Kidney Int 68:2323-30. 2005....
Red blood cell transfusion risks in patients with end-stage renal diseaseYvette C Tanhehco
Division of Laboratory Medicine, Department of Pathology, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, USA
Semin Dial 25:539-44. 2012..This article reviews the modern day infectious and noninfectious risks of allogeneic RBC transfusions...
Effect of darbepoetin alfa on endothelial progenitor cells and vascular reactivity in chronic kidney diseaseEmile R Mohler
Department of Medicine, Cardiovascular Division, Vascular Medicine Section, University of Pennsylvania School of Medicine, PA, USA
Vasc Med 16:183-9. 2011....
The safety of heparins in end-stage renal diseaseSamsher Sonawane
Department of Medicine, Renal, Electrolyte, and Hypertension Division, Penn Presbyterian Medical Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 19:305-10. 2006..UFH still remains the preferred anticoagulant in the vast majority of dialysis patients requiring systemic anticoagulation and for anticoagulation of the extracorporeal hemodialysis circuit...
Use of low molecular weight heparins and glycoprotein IIb/IIIa inhibitors in patients with chronic kidney diseaseAri Mosenkis
Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 17:411-5. 2004..This article examines the available literature regarding the pharmacokinetics, dosing, efficacy, and safety of LMWH and Gp IIb/IIIa inhibitors in patients with CKD...
Willingness of patients to switch from conventional to daily hemodialysis: looking before we leapScott D Halpern
Department of Medicine, University of Pennsylvania, Philadelphia, USA
Am J Med 116:606-12. 2004....
Handoff communication between hospital and outpatient dialysis units at patient discharge: a qualitative studyJames B Reilly
Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA
Jt Comm J Qual Patient Saf 39:70-6. 2013..Little is known about how dialysis-specific information is shared with outpatient dialysis clinics for discharged patients, and the applicability of existing models of handoff transitions is unknown...
Impact of tip culture on the management of infected tunneled hemodialysis cathetersEmily T Cooper
Department of Radiology, Division of Interventional Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
J Vasc Interv Radiol 18:1227-31. 2007..This study was conducted to determine the effect of hemodialysis catheter tip cultures (CTCs) on patient management...
Selection and dosing of medications for management of diabetes in patients with advanced kidney diseaseJames B Reilly
Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Semin Dial 23:163-8. 2010..This article reviews the clinical use of insulin and other antidiabetic therapies, focusing on pharmacokinetic properties and dosing in patients with advanced kidney disease...
Onco-nephrology: tumor lysis syndromeF Perry Wilson
Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 7:1730-9. 2012..Prevention and treatment depend on prompt recognition of patients at risk, volume repletion, allopurinol, rasburicase (a novel recombinant urate oxidase), and, when indicated, dialysis...
Vancomycin levels are frequently subtherapeutic during continuous venovenous hemodialysis (CVVHD)F Perry Wilson
University of Pennsylvania Health System, Department of Medicine, Philadelphia, PA, USA
Clin Nephrol 77:329-31. 2012..Herein we present data demonstrating frequent subtherapeutic levels of vancomycin in a population of patients on CRRT. Nephrology trainees should be educated as to the risks of under-dosing antibiotics in this population...
Quinine--a tonic too bitter for hemodialysis-associated muscle cramps?Sidney M Kobrin
Renal Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania School of Medicine and Hospital of University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Semin Dial 20:396-401. 2007..We review the causes and consequences of hemodialysis-associated cramps, and discuss possible preventive measures and treatments...
Viral nephropathies: core curriculum 2008Jeffrey S Berns
University of Pennsylvania School of Medicine, Renal, Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Am J Kidney Dis 52:370-81. 2008
Use of antiepileptic drugs in patients with kidney diseaseRubeen K Israni
Renal-Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 19:408-16. 2006..Monitoring of drug levels when available, careful clinical assessment of patients taking AEDs, and close collaboration with neurologists is essential to the management of patients taking AEDs...
Predictors of amputation and survival following lower extremity revascularization in hemodialysis patientsBernard G Jaar
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Kidney Int 65:613-20. 2004..We studied the prognosis of ESRD patients undergoing their first revascularization procedure...
When chronic kidney disease becomes advanced. Guidelines for care in the emergency department and hospitalAri Mosenkis
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
Postgrad Med 119:83-91, 104. 2006....
Single-center experience with the Arrow-Trerotola Percutaneous Thrombectomy Device in the management of thrombosed native dialysis fistulasJosh B Shatsky
Department of Radiology, Division of Interventional Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
J Vasc Interv Radiol 16:1605-11. 2005..S. population. Within the limitations of a retrospective study with a small sample size, use of an adjunctive thrombolytic agent did not appear to improve results compared with the use of the device alone...
The renal manifestations of thyroid diseaseLaura H Mariani
University of Pennsylvania School of Medicine, Renal, Electrolyte and Hypertension Division, Presbyterian Medical Center, 39th and Market Streets, MOB 240, Philadelphia, PA 19104, USA
J Am Soc Nephrol 23:22-6. 2012..Disorders of thyroid function have also been linked to development of immune-mediated glomerular injury, and alterations in thyroid hormones and thyroid hormone testing occur in patients with kidney disease...
Use of insulin and oral hypoglycemic medications in patients with diabetes mellitus and advanced kidney diseaseRichard W Snyder
Department of Medicine, Renal, Electrolyte, and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Semin Dial 17:365-70. 2004..In this article we will review the use of insulin and the various classes of oral medications used to treat type 2 diabetes mellitus, focusing on their pharmacokinetic properties and dosing in patients with advanced kidney disease...
Willingness of dialysis patients to participate in a randomized controlled trial of daily dialysisAjay K Israni
Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Kidney Int 65:990-8. 2004..However, there is concern that difficulties recruiting patients may prevent the successful completion of such trials if patients believe the inconveniences of daily dialysis outweigh any potential health benefits...
Recruitment of live donors by candidates for kidney transplantationPETER P REESE
Renal Division, University of Pennsylvania School of Medicine, 1 Founders, 3400 Spruce Street, Philadelphia, PA 19104, USA
Clin J Am Soc Nephrol 3:1152-9. 2008..It was hypothesized that preference for live donor kidney transplantation and greater knowledge about live donor transplantation are associated with candidates' initiating conversations about donation with potential donors...
Creatinine generation is reduced in patients requiring continuous venovenous hemodialysis and independently predicts mortalityFrancis P Wilson
Renal Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Nephrol Dial Transplant 27:4088-94. 2012..Failure to appreciate variation in CGR may lead to erroneous conclusions regarding severity of AKI and distorted predictions regarding patient outcomes based on AKI severity...
What is the nephrologist's role as a primary care provider? We all have different answersJeffrey S Berns
Department of Medicine, Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Clin J Am Soc Nephrol 2:601-3. 2007
Extracorporeal treatment of cast nephropathyBhavna Gakhar
Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Semin Dial 24:9-11. 2011..Further research is necessary to establish the specific efficacy of each of these extracorporeal methods in the treatment of cast nephropathy...
Complications of percutaneous treatment of thrombosed hemodialysis access graftsFrancis L Weng
University of Pennsylvania School of Medicine, Renal, Electrolyte, and Hypertension Division, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
Semin Dial 16:257-62. 2003..This article reviews the epidemiology, clinical significance, and management of these complications...
Clinical evaluation of heme iron polypeptide: sustaining a response to rHuEPO in hemodialysis patientsAllen R Nissenson
University of California, Los Angeles, CA, USA
Am J Kidney Dis 42:325-30. 2003..This treatment was associated with a significant increase in rHuEPO efficiency (P = 0.04)...
Hemoglobin cycling in hemodialysis patients treated with recombinant human erythropoietinSteven Fishbane
Winthrop University Hospital, Mineola, New York, USA
Kidney Int 68:1337-43. 2005..Therapy, however, is often observed to be associated with recurrent cyclic fluctuations in hemoglobin levels. The purpose of this analysis was to describe the phenomenology of hemoglobin cycling during rHuEPO treatment...
Evidence and implications of haemoglobin cycling in anaemia managementSteven Fishbane
Nephrol Dial Transplant 22:2129-32. 2007
How can erythropoietin requirements be reduced in dialysis patients?Peter Kotanko
Renal Research Institute, New York, New York 10128, USA
Semin Dial 19:363-72. 2006
Should all patients with chronic kidney disease receive an EPO-type drug?Jeffrey S Berns
Cleve Clin J Med 73:298-300. 2006
How should chronic medical therapies be altered with the onset of end-stage renal disease and initiation of dialysis?Kathleen L Wyne
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 8857, USA
Semin Dial 19:8-24. 2006
Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American populationMohammed S Orloff
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106 7281, USA
Physiol Genomics 21:212-21. 2005..Furthermore, HIV-1 infection status interacts with genetic variations in both genes to influence this phenotype. We speculate that nephropathy liability alleles in WT1 pathway genes cause podocyte dysfunction and glomerular scarring...
Boning up on lanthanumJeffrey S Berns
Semin Dial 19:87-9. 2006
Niacin and related compounds for treating hyperphosphatemia in dialysis patientsJeffrey S Berns
Semin Dial 21:203-5. 2008....
Is intravenous iron safe in patients with liver disease?Jeffrey S Berns
Semin Dial 15:212-3. 2002
Are inflammatory cytokines the "evil humors" that increase morbidity and cardiovascular mortality in chronic kidney disease?Jonathan S Maltzman
Semin Dial 18:441-3. 2005
Frequency of sit-down patient care rounds, attainment of clinical performance targets, hospitalization, and mortality in hemodialysis patientsJeffrey S Berns
Semin Dial 18:258-60. 2005
