Annerose Berndt

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint Quantitative method of measuring phosphatidylserine externalization during apoptosis using electron paramagnetic resonance (EPR) spectroscopy and annexin-conjugated iron
    James P Fabisiak
    Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Bridgeside Point, Pittsburgh, PA, 15219, USA
    Methods Mol Biol 1105:613-21. 2014
  2. doi request reprint Quantification of selective phosphatidylserine oxidation during apoptosis
    James P Fabisiak
    Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Bridgeside Point, Pittsburgh, PA, 15219, USA
    Methods Mol Biol 1105:603-11. 2014
  3. ncbi request reprint Quantification of oxidative/nitrosative modification of CYS(34) in human serum albumin using a fluorescence-based SDS-PAGE assay
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, 3343 Forbes Avenue, Pittsburgh, PA 15238, USA
    Antioxid Redox Signal 4:855-65. 2002
  4. pmc Mycoplasma fermentans and TNF-beta interact to amplify immune-modulating cytokines in human lung fibroblasts
    James P Fabisiak
    Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh Graduate School of Public Health, College of Medicine, Pittsburgh, PA 15219 3130, USA
    Am J Physiol Lung Cell Mol Physiol 291:L781-93. 2006
  5. pmc Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Mol Nutr Food Res 55:1423-34. 2011
  6. pmc Functional genomic assessment of phosgene-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219, USA
    Am J Respir Cell Mol Biol 49:368-83. 2013
  7. pmc Integrative assessment of chlorine-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219 3130, USA
    Am J Respir Cell Mol Biol 47:234-44. 2012
  8. ncbi request reprint Microbial stimulation by Mycoplasma fermentans synergistically amplifies IL-6 release by human lung fibroblasts in response to residual oil fly ash (ROFA) and nickel
    Fei Gao
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Toxicol Sci 81:467-79. 2004
  9. pmc Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Am J Respir Crit Care Med 183:1499-509. 2011
  10. pmc Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas
    Annerose Berndt
    Berndt Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Cancer Res 71:5779-91. 2011

Research Grants

  1. Particulate Matter/Mycoplasma Stress Interactions
    James Fabisiak; Fiscal Year: 2007

Collaborators

Detail Information

Publications16

  1. doi request reprint Quantitative method of measuring phosphatidylserine externalization during apoptosis using electron paramagnetic resonance (EPR) spectroscopy and annexin-conjugated iron
    James P Fabisiak
    Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Bridgeside Point, Pittsburgh, PA, 15219, USA
    Methods Mol Biol 1105:613-21. 2014
    ....
  2. doi request reprint Quantification of selective phosphatidylserine oxidation during apoptosis
    James P Fabisiak
    Department of Environmental and Occupational Health, University of Pittsburgh, 100 Technology Drive, Bridgeside Point, Pittsburgh, PA, 15219, USA
    Methods Mol Biol 1105:603-11. 2014
    ..These experimental approaches can provide insight into the roles and mechanisms of PS oxidation in the identification and clearance of apoptotic cells. ..
  3. ncbi request reprint Quantification of oxidative/nitrosative modification of CYS(34) in human serum albumin using a fluorescence-based SDS-PAGE assay
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, 3343 Forbes Avenue, Pittsburgh, PA 15238, USA
    Antioxid Redox Signal 4:855-65. 2002
    ....
  4. pmc Mycoplasma fermentans and TNF-beta interact to amplify immune-modulating cytokines in human lung fibroblasts
    James P Fabisiak
    Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh Graduate School of Public Health, College of Medicine, Pittsburgh, PA 15219 3130, USA
    Am J Physiol Lung Cell Mol Physiol 291:L781-93. 2006
    ..Thus M. fermentans interacts with stimuli such as TNF-beta to amplify lung cell production of immune-modulating cytokines. The mechanisms accounting for this interaction can now be dissected with the use of this in vitro model...
  5. pmc Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Mol Nutr Food Res 55:1423-34. 2011
    ..A respiratory irritant, acrolein is generated by overheating cooking oils or by domestic cooking using biomass fuels, and is in environmental tobacco smoke, a health hazard in the restaurant workplace...
  6. pmc Functional genomic assessment of phosgene-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219, USA
    Am J Respir Cell Mol Biol 49:368-83. 2013
    ..In addition, a gene with a suggestive SNP association, Itga9, is linked to transforming growth factor β1 signaling, which previously has been associated with the susceptibility to ALI in mice. ..
  7. pmc Integrative assessment of chlorine-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219 3130, USA
    Am J Respir Cell Mol Biol 47:234-44. 2012
    ..The leading candidate genes associated with increased susceptibility to acute lung injury in mice included Klf4, Sema7a, Tns1, Aacs, and a gene that encodes an amino acid carrier, Slc38a4...
  8. ncbi request reprint Microbial stimulation by Mycoplasma fermentans synergistically amplifies IL-6 release by human lung fibroblasts in response to residual oil fly ash (ROFA) and nickel
    Fei Gao
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Toxicol Sci 81:467-79. 2004
    ....
  9. pmc Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Am J Respir Crit Care Med 183:1499-509. 2011
    ..Because acute lung injury is a sporadic disease produced by heterogeneous precipitating factors, previous genetic analyses are mainly limited to candidate gene case-control studies...
  10. pmc Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas
    Annerose Berndt
    Berndt Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Cancer Res 71:5779-91. 2011
    ....
  11. pmc Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene
    Annerose Berndt
    The Jackson Laboratory, Bar Harbor, ME, USA
    Mol Genet Genomics 286:237-46. 2011
    ..Conclusively, Vdr contributes to the phenotypic variation of lung resistance in inbred mice but other molecules in the Vdr pathway and extended network [i.e., Chr X gene(s)] may contribute as well...
  12. pmc Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathway
    Kelly A Brant
    Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15219 3130, USA
    Toxicol Sci 107:227-37. 2009
    ....
  13. pmc Nickel alterations of TLR2-dependent chemokine profiles in lung fibroblasts are mediated by COX-2
    Kelly A Brant
    University of Pittsburgh Graduate School of Public Health, Department of Environmental and Occupational Health, Bridgeside Point, 100 Technology Drive, Room 327, BRIDG, Pittsburgh, PA 15219 3130, USA
    Am J Respir Cell Mol Biol 38:591-9. 2008
    ..The quantitative and qualitative effects of NiSO(4) on microbial-driven chemokine release from HLF shed new light on how PM-derived metals can exacerbate respiratory diseases...
  14. pmc Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2
    Fei Gao
    Department of Environmental and Occupational Health, Center for Free Radical and Antioxidant Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15219, USA
    Toxicol Appl Pharmacol 247:146-57. 2010
    ....
  15. ncbi request reprint Redox sensor function of metallothioneins
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Methods Enzymol 353:268-81. 2002
    ....
  16. pmc Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity
    Anna A Shvedova
    Pathology Physiology Research Branch, HELD, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA
    Am J Respir Cell Mol Biol 38:579-90. 2008
    ..In conclusion, enhanced acute inflammation and pulmonary injury with delayed bacterial clearance after SWCNT exposure may lead to increased susceptibility to lung infection in exposed populations...

Research Grants6

  1. Particulate Matter/Mycoplasma Stress Interactions
    James Fabisiak; Fiscal Year: 2007
    ..The identification of microbial agents as determinants of host-cell response to chemical stress will necessitate that microbial ecology be taken into consideration in the assessment of risk posed by atmospheric pollutants such as ROFA. ..