Annerose Berndt

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Emerging genetics of COPD
    Annerose Berndt
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, PA, USA
    EMBO Mol Med 4:1144-55. 2012
  2. pmc Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice
    Annerose Berndt
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Physiol Genomics 43:1-11. 2011
  3. pmc Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas
    Annerose Berndt
    Berndt Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Cancer Res 71:5779-91. 2011
  4. pmc Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene
    Annerose Berndt
    The Jackson Laboratory, Bar Harbor, ME, USA
    Mol Genet Genomics 286:237-46. 2011
  5. doi request reprint Early gene expression differences in inbred mouse strains with susceptibility to pulmonary adenomas
    Timothy M Stearns
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Exp Mol Pathol 93:455-61. 2012
  6. pmc Functional genomic assessment of phosgene-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219, USA
    Am J Respir Cell Mol Biol 49:368-83. 2013
  7. pmc Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Mol Nutr Food Res 55:1423-34. 2011
  8. pmc A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci
    Adriana S Leme
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Mol Genet Genomics 283:317-26. 2010
  9. pmc Alopecia areata: updates from the mouse perspective
    John P Sundberg
    1 Department of Research, The Jackson Laboratory, Bar Harbor, Maine, USA 2 Division of Dermatology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    J Investig Dermatol Symp Proc 16:S23-4. 2013
  10. pmc c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice
    James Y Lindsey
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Am J Respir Crit Care Med 183:1644-52. 2011

Collaborators

Detail Information

Publications11

  1. pmc Emerging genetics of COPD
    Annerose Berndt
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, PA, USA
    EMBO Mol Med 4:1144-55. 2012
    ..Here, we review the discovery of genetic variants in association with COPD phenotypes by discussing the available approaches and current findings. Limitations of current studies are considered and future directions provided...
  2. pmc Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice
    Annerose Berndt
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Physiol Genomics 43:1-11. 2011
    ..e., genome-wide association studies or quantitative trait locus studies) measures something fundamentally different than airway resistance and lung elastance...
  3. pmc Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas
    Annerose Berndt
    Berndt Laboratory, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Cancer Res 71:5779-91. 2011
    ....
  4. pmc Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene
    Annerose Berndt
    The Jackson Laboratory, Bar Harbor, ME, USA
    Mol Genet Genomics 286:237-46. 2011
    ..Conclusively, Vdr contributes to the phenotypic variation of lung resistance in inbred mice but other molecules in the Vdr pathway and extended network [i.e., Chr X gene(s)] may contribute as well...
  5. doi request reprint Early gene expression differences in inbred mouse strains with susceptibility to pulmonary adenomas
    Timothy M Stearns
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Exp Mol Pathol 93:455-61. 2012
    ..Finally, the identified genes have previously been reported for human non-small cell lung cancer suggesting that molecular pathways may be shared between these two cancer types...
  6. pmc Functional genomic assessment of phosgene-induced acute lung injury in mice
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219, USA
    Am J Respir Cell Mol Biol 49:368-83. 2013
    ..In addition, a gene with a suggestive SNP association, Itga9, is linked to transforming growth factor β1 signaling, which previously has been associated with the susceptibility to ALI in mice. ..
  7. pmc Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injury
    James P Fabisiak
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Mol Nutr Food Res 55:1423-34. 2011
    ..A respiratory irritant, acrolein is generated by overheating cooking oils or by domestic cooking using biomass fuels, and is in environmental tobacco smoke, a health hazard in the restaurant workplace...
  8. pmc A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci
    Adriana S Leme
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Mol Genet Genomics 283:317-26. 2010
    ..Our analyses have narrowed the possible QTL genes and will facilitate the discovery of novel genes that regulate AHR in mice...
  9. pmc Alopecia areata: updates from the mouse perspective
    John P Sundberg
    1 Department of Research, The Jackson Laboratory, Bar Harbor, Maine, USA 2 Division of Dermatology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
    J Investig Dermatol Symp Proc 16:S23-4. 2013
    ..Comparing these model systems with human and mouse clinical disease, for both discovery and validation of the discoveries, continues to resolve the complex questions surrounding AA. ..
  10. pmc c-Kit is essential for alveolar maintenance and protection from emphysema-like disease in mice
    James Y Lindsey
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Am J Respir Crit Care Med 183:1644-52. 2011
    ..Increases in the percentage of cells expressing c-Kit have previously been associated with protection against injury-induced emphysema...
  11. pmc Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1
    George D Leikauf
    Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
    Am J Respir Crit Care Med 183:1499-509. 2011
    ..Because acute lung injury is a sporadic disease produced by heterogeneous precipitating factors, previous genetic analyses are mainly limited to candidate gene case-control studies...