Judith G Berman

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance
    Anna M Selmecki
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS Genet 5:e1000705. 2009
  2. pmc Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase
    Amnon Koren
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS Genet 6:e1001068. 2010
  3. pmc The 'obligate diploid' Candida albicans forms mating-competent haploids
    Meleah A Hickman
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 494:55-9. 2013
  4. pmc Morphogenesis and cell cycle progression in Candida albicans
    Judith Berman
    Department of Genetics, Cell Biology and Development, 6 160 Jackson Hall, 321 Church Street SE, University of Minnesota, Minneapolis, MN 55455, USA
    Curr Opin Microbiol 9:595-601. 2006
  5. pmc Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus
    Lynn Glowczewski
    Department of Genetics, Cell Biology and Development, University of Minnesota, 6 170 MCB Building, 420 Washington Ave SE, Minneapolis, MN 55455, USA
    Mol Cell Biol 24:10180-92. 2004
  6. pmc SLA2 mutations cause SWE1-mediated cell cycle phenotypes in Candida albicans and Saccharomyces cerevisiae
    Cheryl A Gale
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Microbiology 155:3847-59. 2009
  7. ncbi request reprint Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p
    Eric S Bensen
    Department of Genetics and Cell Development, University of Minnesota, MN 55455, USA
    Mol Microbiol 54:1335-51. 2004
  8. pmc The mitotic cyclins Clb2p and Clb4p affect morphogenesis in Candida albicans
    Eric S Bensen
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Mol Biol Cell 16:3387-400. 2005
  9. pmc A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans
    Eric S Bensen
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Eukaryot Cell 1:787-98. 2002
  10. pmc Microtubules in Candida albicans hyphae drive nuclear dynamics and connect cell cycle progression to morphogenesis
    Kenneth R Finley
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, Minnesota 55455, USA
    Eukaryot Cell 4:1697-711. 2005

Research Grants

  1. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2006
  2. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2006
  3. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2007
  4. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2009
  5. Centromere Structure and Function in Candida albicans
    Judith Berman; Fiscal Year: 2009
  6. Centromere Structure and Function in Candida albicans
    Judith G Berman; Fiscal Year: 2010
  7. Genome Integrity in Candida albicans
    Judith G Berman; Fiscal Year: 2010
  8. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2005
  9. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2005
  10. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2004

Collaborators

Detail Information

Publications30

  1. pmc Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance
    Anna M Selmecki
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS Genet 5:e1000705. 2009
    ..The early appearance of aneuploidy is consistent with a model in which C. albicans becomes more permissive of chromosome rearrangements and segregation defects in the presence of fluconazole...
  2. pmc Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase
    Amnon Koren
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota, USA
    PLoS Genet 6:e1001068. 2010
    ..We suggest a model in which the distinct timing of DNA replication serves as an epigenetic mechanism for the inheritance of centromere position...
  3. pmc The 'obligate diploid' Candida albicans forms mating-competent haploids
    Meleah A Hickman
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 494:55-9. 2013
    ..Finally, we constructed stable haploid strains with multiple auxotrophies that will facilitate molecular and genetic analyses of this important pathogen...
  4. pmc Morphogenesis and cell cycle progression in Candida albicans
    Judith Berman
    Department of Genetics, Cell Biology and Development, 6 160 Jackson Hall, 321 Church Street SE, University of Minnesota, Minneapolis, MN 55455, USA
    Curr Opin Microbiol 9:595-601. 2006
    ..Future work will probably focus on the cell cycle checkpoints involved in connecting morphogenesis to cell cycle progression...
  5. pmc Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus
    Lynn Glowczewski
    Department of Genetics, Cell Biology and Development, University of Minnesota, 6 170 MCB Building, 420 Washington Ave SE, Minneapolis, MN 55455, USA
    Mol Cell Biol 24:10180-92. 2004
    ..In addition, our data support a model whereby Cac1p and Kap123 cooperate to ensure that only appropriately acetylated histone H4 proteins are imported into the nucleus...
  6. pmc SLA2 mutations cause SWE1-mediated cell cycle phenotypes in Candida albicans and Saccharomyces cerevisiae
    Cheryl A Gale
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Microbiology 155:3847-59. 2009
    ..Furthermore, Swe1 contributed to virulence in a mouse model of disseminated candidiasis, implying a role for the morphogenesis checkpoint during the pathogenesis of C. albicans infections...
  7. ncbi request reprint Transcriptional profiling in Candida albicans reveals new adaptive responses to extracellular pH and functions for Rim101p
    Eric S Bensen
    Department of Genetics and Cell Development, University of Minnesota, MN 55455, USA
    Mol Microbiol 54:1335-51. 2004
    ..We found that rim101-/- cells are sensitive to iron starvation, which suggests that one important aspect of the Rim101p-dependent alkaline pH response is to adapt to iron starvation conditions...
  8. pmc The mitotic cyclins Clb2p and Clb4p affect morphogenesis in Candida albicans
    Eric S Bensen
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Mol Biol Cell 16:3387-400. 2005
    ..In addition, overexpression of either B-type cyclin reduced the extent of filamentous growth. Taken together, these data indicate that Clb2p and Clb4p regulate C. albicans morphogenesis by negatively regulating polarized growth...
  9. pmc A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans
    Eric S Bensen
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Eukaryot Cell 1:787-98. 2002
    ..In addition, cells lacking Fkh2p were unable to damage human epithelial or endothelial cells in vitro, suggesting that Fkh2p contributes to C. albicans virulence...
  10. pmc Microtubules in Candida albicans hyphae drive nuclear dynamics and connect cell cycle progression to morphogenesis
    Kenneth R Finley
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, Minnesota 55455, USA
    Eukaryot Cell 4:1697-711. 2005
    ..Finally, a growth defect in strains expressing Tub2-green fluorescent protein revealed a connection between hyphal elongation and the nuclear cell cycle that is coordinated by hyphal length and/or volume...
  11. pmc Molecular genetic and genomic approaches to the study of medically important fungi
    P T Magee
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Infect Immun 71:2299-309. 2003
  12. ncbi request reprint Candida Albicans: a molecular revolution built on lessons from budding yeast
    Judith Berman
    Department of Genetics, Cell Biology and Development, 6 160 Jackson Hall, 321 Church Street SE, Minneapolis, Minnesota 55455, USA
    Nat Rev Genet 3:918-30. 2002
    ..They also reveal the extent of similarities and differences between C. albicans and its benign relative, Saccharomyces cerevisiae...
  13. pmc Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans
    Kelly Bouchonville
    University of Minnesota, GCD, 6 160 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
    Eukaryot Cell 8:1554-66. 2009
    ..Thus, aneuploid strains are particularly prone to undergo changes in chromosome number during the stresses of DNA transformation protocols...
  14. pmc Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells
    Shinichiro Enomoto
    Department of Genetics, Cell Biology and Development, University of Minnesota, 6 170 MCB Building, 420 Washington Avenue SE, Minneapolis, MN 55455, USA
    Mol Cell Biol 24:837-45. 2004
    ..Furthermore, the NMD pathway affects the rate of senescence in telomerase-deficient cells by altering the stoichiometry of telomere cap components...
  15. pmc Evolution in Candida albicans populations during a single passage through a mouse host
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Genetics 182:799-811. 2009
    ..Results suggest that the dynamics of population growth and genomewide rearrangement contribute to the maintenance of a commensal and opportunistic life history of C. albicans...
  16. doi request reprint Dynein-dependent nuclear dynamics affect morphogenesis in Candida albicans by means of the Bub2p spindle checkpoint
    Kenneth R Finley
    Department of Genetics, Cell Biology, and Development, University of Minnesota Minneapolis, Minneapolis, MN 55455, USA
    J Cell Sci 121:466-76. 2008
    ..Thus, Bub2p has two distinct roles in C. albicans cells lacking dynein: it mediates pre-anaphase arrest and it coordinates spindle disassembly with mitotic exit...
  17. ncbi request reprint Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains
    Anna Selmecki
    Department of Genetics, Cell Biology and Development, University of Minnesota, MN, USA
    Mol Microbiol 55:1553-65. 2005
    ..albicans strains. Furthermore, they highlight the high level of genome instability in C. albicans laboratory strains exposed to the stress of transformation and counterselection on 5-fluoro-orotic acid...
  18. pmc MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae
    Shinichiro Enomoto
    Department of Genetics, Cell Biology and Development, University of Minnesota, St Paul 55108, USA
    Mol Biol Cell 13:2626-38. 2002
    ..We propose that the telomere checkpoint is distinct from the DNA damage checkpoint and requires a specific set of gene products to delay the cell cycle and presumably to activate telomerase and/or other telomere repair activities...
  19. pmc Low dosage of histone H4 leads to growth defects and morphological changes in Candida albicans
    Lucia F Zacchi
    Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS ONE 5:e10629. 2010
    ..This is the first study of a core nucleosomal histone in C. albicans, and constitutes the prelude to future, more detailed research on the function of histone H4 in this important fungal pathogen...
  20. pmc Genomic plasticity of the human fungal pathogen Candida albicans
    Anna Selmecki
    Department of Genetics, Cell Biology, and Development, 6 160 Jackson Hall, University of Minnesota, Minneapolis, MN 55455, USA
    Eukaryot Cell 9:991-1008. 2010
    ..albicans may provide important insights into how these processes occur in higher-eukaryotic cells exposed to stresses such as anticancer drugs...
  21. doi request reprint An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
    Anna Selmecki
    Department of Genetics, Cell and Development, University of Minnesota, Minneapolis, MN 55305, USA
    Mol Microbiol 68:624-41. 2008
    ..Thus, the major mechanism by which i(5L) formation causes increased azole resistance is by amplifying two genes: ERG11 and TAC1...
  22. pmc Additional cassettes for epitope and fluorescent fusion proteins in Candida albicans
    Maryam Gerami-Nejad
    Department of Genetics, Cell Biology and Development, University of Minnesota, MN 55455, USA
    Yeast 26:399-406. 2009
    ..These reagents expand the repertoire of molecular tools available for working with C. albicans and other members of the CUG clade of pathogenic yeasts...
  23. pmc The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Biol 6:e110. 2008
    ..albicans. We discuss, in light of the long association of C. albicans with warm-blooded animals, the potential advantages of a parasexual cycle over a conventional sexual cycle...
  24. pmc Aneuploidy and isochromosome formation in drug-resistant Candida albicans
    Anna Selmecki
    Department of Genetics, Cell Biology, and Development, University of Minnesota, 6 160 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Science 313:367-70. 2006
    ....
  25. ncbi request reprint Cassettes for the PCR-mediated construction of regulatable alleles in Candida albicans
    Maryam Gerami-Nejad
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
    Yeast 21:429-36. 2004
    ..Thus, these promoter cassette plasmids facilitate construction of conditional mutant strains, overexpression alleles and/or inducible amino-terminal GFP fusion proteins...
  26. pmc Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies
    Melanie Legrand
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Genet 4:e1. 2008
    ..Therefore, induced aneuploidies can be used to generate HapMaps, which are essential for analyzing genome alterations and mitotic recombination events in this clonal organism...
  27. pmc Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP
    Anja Forche
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA
    FEMS Yeast Res 9:1061-9. 2009
    ..While less comprehensive than array-based approaches, we propose SNP-RFLP as an inexpensive, rapid, and reliable method to screen strains of interest for possible genome changes...
  28. pmc Neocentromeres form efficiently at multiple possible loci in Candida albicans
    Carrie Ketel
    Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota, United States of America
    PLoS Genet 5:e1000400. 2009
    ..The ability to select for neocentromere formation and movement in C. albicans permits mechanistic analysis of the assembly and maintenance of a regional centromere...

Research Grants23

  1. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2006
    ..abstract_text> ..
  2. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2006
    ..Ultimately, fungal-specific gene products that execute essential cell cycle processes may be important new targets for the development of anti-fungal therapies. ..
  3. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2007
    ..abstract_text> ..
  4. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2009
    ..abstract_text> ..
  5. Centromere Structure and Function in Candida albicans
    Judith Berman; Fiscal Year: 2009
    ..We will develop tools to study this process and will identify companion drugs that inhibit these defects, thereby extending the usefulness of available antifungal therapies. ..
  6. Centromere Structure and Function in Candida albicans
    Judith G Berman; Fiscal Year: 2010
    ..We will develop tools to study this process and will identify companion drugs that inhibit these defects, thereby extending the usefulness of available antifungal therapies. ..
  7. Genome Integrity in Candida albicans
    Judith G Berman; Fiscal Year: 2010
    ....
  8. Genome Integrity in Candida albicans
    Judith Berman; Fiscal Year: 2005
    ..abstract_text> ..
  9. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2005
    ..Ultimately, fungal-specific gene products that execute essential cell cycle processes may be important new targets for the development of anti-fungal therapies. ..
  10. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2004
    ..Ultimately, fungal-specific gene products that execute essential cell cycle processes may be important new targets for the development of anti-fungal therapies. ..
  11. TELOMERE ORGANIZATION AND FUNCTION IN S CERVISIAE
    Judith Berman; Fiscal Year: 1999
    ....
  12. TELOMERE ORGANIZATION AND FUNCTION IN S CERVISIAE
    Judith Berman; Fiscal Year: 2000
    ....
  13. TELOMERE ORGANIZATION AND FUNCTION IN S CERVISIAE
    Judith Berman; Fiscal Year: 2001
    ....
  14. TELOMERE ORGANIZATION AND FUNCTION IN S CERVISIAE
    Judith Berman; Fiscal Year: 2002
    ....
  15. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2002
    ..Ultimately, fungal-specific gene products that execute essential cell cycle processes may be important new targets for the development of anti-fungal therapies. ..
  16. Morphogenesis and Cell Cycle Regulation in C. albicans
    Judith Berman; Fiscal Year: 2003
    ..Ultimately, fungal-specific gene products that execute essential cell cycle processes may be important new targets for the development of anti-fungal therapies. ..
  17. Centromere Structure and Function in Candida albicans
    Judith G Berman; Fiscal Year: 2010
    ..We will develop tools to study this process and will identify companion drugs that inhibit these defects, thereby extending the usefulness of available antifungal therapies. ..