Research Topics
| LARS F BERGLUNDSummaryAffiliation: University of California Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
The association of hypertriglyceridemia with cardiovascular events and pancreatitis: a systematic review and meta-analysisM Hassan Murad
Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA
BMC Endocr Disord 12:2. 2012..abstract:..- Cardiovascular disease in women--challenges deserving a comprehensive translational approachJennifer S Lee
Department of Medicine, University of California, Davis, UC Davis Medical Center, CTSC, 2921 Stockton Blvd, Suite 1400, Sacramento, CA 95817, USA
J Cardiovasc Transl Res 2:251-5. 2009.... - Postprandial lipoproteins and cardiovascular disease risk in diabetes mellitusByambaa Enkhmaa
Department of Medicine, UCD Medical Center, CTSC, University of California, Davis, 2921 Stockton Boulevard, Suite 1400, Sacramento, CA 95817, USA
Curr Diab Rep 10:61-9. 2010..The findings provide a challenge to develop a better approach to assess the impact of postprandial lipemia on CVD risk under diabetic conditions... 
Strategies for innovation and interdisciplinary translational research: removal of barriers through the CTSA mechanismLars Berglund
Departments of Medicine, Pediatrics, and Cell Biology and Human Anatomy, University of California, Davis, Sacramento, CA, USA
J Investig Med 57:474-6. 2009....
Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial statesLars Berglund
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Am J Clin Nutr 86:1611-20. 2007..In subjects with a high prevalence of metabolic risk abnormalities, the preferred replacement for saturated fat is unresolved...- Postprandial response to a physiologic caloric load in HIV-positive patients receiving protease inhibitor-based or nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapyAsha Thomas-Geevarghese
Department of Medicine and the General Clinical Research Center, Harlem Hospital Center and Columbia University, New York, NY, USA
Am J Clin Nutr 82:146-54. 2005..CONCLUSIONS: Despite baseline differences, incremental triacylglycerol and insulin responses to a physiologic caloric load among HIV-positive patients were not significantly affected by differences in the type of antiretroviral therapy... - Lipoprotein(a): an elusive cardiovascular risk factorLars Berglund
Department of Medicine, University of California, Davis, UCD Medical Center, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
Arterioscler Thromb Vasc Biol 24:2219-26. 2004..Further, there is an interaction between Lp(a) and other risk factors for cardiovascular disease. The physiological role of Lp(a) is unknown, although a majority of studies implicate Lp(a) as a risk factor... - Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humansKimber L Stanhope
Department of Molecular Biosciences, UCD, Davis, California 95616, USA
J Clin Invest 119:1322-34. 2009..These data suggest that dietary fructose specifically increases DNL, promotes dyslipidemia, decreases insulin sensitivity, and increases visceral adiposity in overweight/obese adults... - Postprandial metabolic responses to dietary glycemic index in hypercholesterolemic postmenopausal womenRadhika N Bukkapatnam
Department of Internal Medicine, University of California, Davis, CA 95616, USA
Prev Cardiol 13:29-35. 2010..The results suggest a postprandial impact of glycemic index on cardiovascular metabolic biomarkers in postmenopausal women and may have implications for dietary glycemic modification of cardiovascular risk in women... - Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitusGissette Reyes-Soffer
Departments of Medicine, Columbia University Medical Center, New York, NY 10032, USA
J Lipid Res 50:1901-9. 2009..PP measurements of TG-rich lipoproteins do not predict the presence of CAD in individuals with DM... - Postprandial lipemia and cardiovascular diseaseDianne Hyson
Department of Medicine, University of California, Davis, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
Curr Atheroscler Rep 5:437-44. 2003..Collectively, these data suggest that assessment and treatment of atherosclerosis should include parameters related to postprandial lipemia... - Increased lipoprotein remnant cholesterol levels in HIV-positive patients during antiretroviral therapyErdembileg Anuurad
Department of Medicine, University of California, Davis, CA 95817, USA
Atherosclerosis 198:192-7. 2008..024, ANOVA). In conclusion, during HIV conditions, HAART resulted in a pro-atherogenic pattern with accumulation of remnant lipoproteins... - Metabolic syndrome components in african-americans and European-american patients and its relation to coronary artery diseaseErdembileg Anuurad
Department of Medicine, University of California Davis, Davis, California, USA
Am J Cardiol 100:830-4. 2007..Although our findings may not be directly extrapolated to the population at large, they illustrate the importance of a high-risk metabolic environment as a cardiovascular risk factor... - Usefulness of apolipoprotein B/apolipoprotein A-I ratio to predict coronary artery disease independent of the metabolic syndrome in African AmericansByambaa Enkhmaa
Department of Medicine, University of California, Davis, Sacramento, USA
Am J Cardiol 106:1264-9. 2010..023). In conclusion, the apoB/apoA-I ratio differed across ethnicities and was associated with presence of the MS in both groups. Among African Americans, an elevated apoB/apoA-I ratio independently predicted a greater risk of CAD... - Relationship of postprandial nonesterified fatty acids, adipokines, and insulin across gender in human immunodeficiency virus-positive patients undergoing highly active antiretroviral therapyGuijing Lu
Department of Medicine, University of California Davis, Sacramento, California 95817, USA
Metab Syndr Relat Disord 7:199-204. 2009..Metabolic derangements are common in human immunodeficiency virus (HIV)-positive subjects undergoing antiretroviral therapy, but little is known about postprandial conditions... - Apolipoprotein E and diets: a case of gene-nutrient interaction?Jill Rubin
Department of Medicine, Columbia University, New York, New York, USA
Curr Opin Lipidol 13:25-32. 2002..Studies directly designed to examine apolipoprotein E gene-nutrient interactions are needed... - Treatment with high-dose simvastatin reduces secretion of apolipoprotein B-lipoproteins in patients with diabetic dyslipidemiaMerle Myerson
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Lipid Res 46:2735-44. 2005..Activation of PPARalpha could lead to increased hepatic oxidation of fatty acids and less synthesis of TG for VLDL assembly... - Fasting plasma insulin modulates lipid levels and particle sizes in 2- to 3-year-old childrenSteven Shea
Division of General Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Obes Res 11:709-21. 2003..We examined the relation of fasting insulin to lipid levels and lipid particle size in young healthy children... - Age as a modulator of inflammatory cardiovascular risk factorsErdembileg Anuurad
Department of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Arterioscler Thromb Vasc Biol 31:2151-6. 2011..We assessed the relationship with age of inflammatory markers, representing (1) systemic (C-reactive protein, fibrinogen, and serum amyloid-A) and (2) vascular (lipoprotein-associated phospholipase A(2) and pentraxin-3) inflammation... - Association of Lp-PLA(2) activity with allele-specific Lp(a) levels in a bi-ethnic populationByambaa Enkhmaa
Department of Medicine, University of California, Davis, CA, USA
Atherosclerosis 211:526-30. 2010..We investigated the association between Lp-PLA(2) activity and allele-specific apolipoprotein(a) [apo(a)] levels in a bi-ethnic population... - The common insertional polymorphism in the APOC1 promoter is associated with serum apolipoprotein C-I levels in Hispanic childrenNeil S Shachter
Department of Medicine, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Atherosclerosis 179:387-93. 2005..These findings suggest that the mechanism of the previously described association with plasma TG is, at least in part, related to the correlation of the polymorphism with the level of expression of apoC-I... - Translational nutrition research at UC Davis--the key role of the Clinical and Translational Science CenterSidika Kasim-Karakas
Department of Medicine, University of California Davis, Sacramento, California 95817, USA
Ann N Y Acad Sci 1190:179-83. 2010..The CTSC has impacted virtually every area and infrastructure resource involved in promoting clinical and translational research at our institution... - Human immunodeficiency virus and highly active antiretroviral therapy-associated metabolic disorders and risk factors for cardiovascular diseaseErdembileg Anuurad
Department of Medicine, University of California Davis, Sacramento, California 95817, USA
Metab Syndr Relat Disord 7:401-10. 2009.... - ApoE and ApoC-I polymorphisms: association of genotype with cardiovascular disease phenotype in African AmericansErdembileg Anuurad
Department of Medicine, University of California, Davis, CA, USA
J Lipid Res 50:1472-8. 2009..e., higher LDL cholesterol and apoB levels), compared with subjects without CAD. ApoC-I genotypes showed an ethnically distinct phenotype relationship with regard to CAD and CAD risk factors... - Protective effect of apolipoprotein E2 on coronary artery disease in African Americans is mediated through lipoprotein cholesterolErdembileg Anuurad
Department of Medicine, University of California, Davis, CA, USA
J Lipid Res 47:2475-81. 2006.... - Lipoprotein(a) and thrombocytes: potential mechanisms underlying cardiovascular riskWilliam Discepolo
Department of Medicine, University of California Davis, 95817, USA
Pathophysiol Haemost Thromb 35:314-21. 2006..On balance, results indicate an effect by Lp(a) on platelet function and future studies focused on specific Lp(a) components, such as the role of apo(a) and of the LDL-like lipid moiety, are needed... - Relation of Apo(a) size to carotid atherosclerosis in an elderly multiethnic populationFurcy Paultre
Department of Medicine, Columbia University, New York, NY 10032, USA
Arterioscler Thromb Vasc Biol 22:141-6. 2002..03). This association was significant for all men (P=0.03) and for white women (P=0.007). The results suggest that molecular properties of apo(a) are important in determining the atherogenicity of Lp(a)...
Research Grants
- UC Davis Clinical and Translational Science CenterLars Berglund; Fiscal Year: 2007..The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
- Regulation of Lipoprotein(a) Metabolism in Humans with Reference to EthnicityLars Berglund; Fiscal Year: 2009..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..
- UC Davis Clinical and Translational Science CenterLars Berglund; Fiscal Year: 2007..The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
- UC Davis Clinical and Translational Science CenterLars Berglund; Fiscal Year: 2007..The UC Davis CTSCwill be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
- REGULATION OF LIPOPROTEIN (A) METABOLISM IN HUMANSLars Berglund; Fiscal Year: 2003..In addition, the investigators hope that their results with provide a framework for approaches to influence Lp(a) in clinical settings. ..
- LIPOPROTEIN AND ADIPOSE TISSUE METABOLISM IN HIVLars Berglund; Fiscal Year: 2004..abstract_text> ..
- Regulation of Lipoprotein(a) Metabolism in Humans with Reference to EthnicityLARS F BERGLUND; Fiscal Year: 2010..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..