LARS F BERGLUND

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans
    Chad L Cox
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA
    Nutr Metab (Lond) 9:68. 2012
  2. pmc The association of hypertriglyceridemia with cardiovascular events and pancreatitis: a systematic review and meta-analysis
    M Hassan Murad
    Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA
    BMC Endocr Disord 12:2. 2012
  3. pmc Cardiovascular disease in women--challenges deserving a comprehensive translational approach
    Jennifer S Lee
    Department of Medicine, University of California, Davis, UC Davis Medical Center, CTSC, 2921 Stockton Blvd, Suite 1400, Sacramento, CA 95817, USA
    J Cardiovasc Transl Res 2:251-5. 2009
  4. pmc Postprandial lipoproteins and cardiovascular disease risk in diabetes mellitus
    Byambaa Enkhmaa
    Department of Medicine, UCD Medical Center, CTSC, University of California, Davis, 2921 Stockton Boulevard, Suite 1400, Sacramento, CA 95817, USA
    Curr Diab Rep 10:61-9. 2010
  5. doi request reprint Strategies for innovation and interdisciplinary translational research: removal of barriers through the CTSA mechanism
    Lars Berglund
    Departments of Medicine, Pediatrics, and Cell Biology and Human Anatomy, University of California, Davis, Sacramento, CA, USA
    J Investig Med 57:474-6. 2009
  6. ncbi request reprint Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states
    Lars Berglund
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 86:1611-20. 2007
  7. pmc Lipoprotein(a): an elusive cardiovascular risk factor
    Lars Berglund
    Department of Medicine, University of California, Davis, UCD Medical Center, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
    Arterioscler Thromb Vasc Biol 24:2219-26. 2004
  8. ncbi request reprint Postprandial response to a physiologic caloric load in HIV-positive patients receiving protease inhibitor-based or nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    Asha Thomas-Geevarghese
    Department of Medicine and the General Clinical Research Center, Harlem Hospital Center and Columbia University, New York, NY, USA
    Am J Clin Nutr 82:146-54. 2005
  9. pmc Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
    Kimber L Stanhope
    Department of Molecular Biosciences, UCD, Davis, California 95616, USA
    J Clin Invest 119:1322-34. 2009
  10. pmc Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitus
    Gissette Reyes-Soffer
    Departments of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    J Lipid Res 50:1901-9. 2009

Collaborators

Detail Information

Publications28

  1. pmc Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans
    Chad L Cox
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA
    Nutr Metab (Lond) 9:68. 2012
    ..abstract:..
  2. pmc The association of hypertriglyceridemia with cardiovascular events and pancreatitis: a systematic review and meta-analysis
    M Hassan Murad
    Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA
    BMC Endocr Disord 12:2. 2012
    ..abstract:..
  3. pmc Cardiovascular disease in women--challenges deserving a comprehensive translational approach
    Jennifer S Lee
    Department of Medicine, University of California, Davis, UC Davis Medical Center, CTSC, 2921 Stockton Blvd, Suite 1400, Sacramento, CA 95817, USA
    J Cardiovasc Transl Res 2:251-5. 2009
    ....
  4. pmc Postprandial lipoproteins and cardiovascular disease risk in diabetes mellitus
    Byambaa Enkhmaa
    Department of Medicine, UCD Medical Center, CTSC, University of California, Davis, 2921 Stockton Boulevard, Suite 1400, Sacramento, CA 95817, USA
    Curr Diab Rep 10:61-9. 2010
    ..The findings provide a challenge to develop a better approach to assess the impact of postprandial lipemia on CVD risk under diabetic conditions...
  5. doi request reprint Strategies for innovation and interdisciplinary translational research: removal of barriers through the CTSA mechanism
    Lars Berglund
    Departments of Medicine, Pediatrics, and Cell Biology and Human Anatomy, University of California, Davis, Sacramento, CA, USA
    J Investig Med 57:474-6. 2009
    ....
  6. ncbi request reprint Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states
    Lars Berglund
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Clin Nutr 86:1611-20. 2007
    ..In subjects with a high prevalence of metabolic risk abnormalities, the preferred replacement for saturated fat is unresolved...
  7. pmc Lipoprotein(a): an elusive cardiovascular risk factor
    Lars Berglund
    Department of Medicine, University of California, Davis, UCD Medical Center, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
    Arterioscler Thromb Vasc Biol 24:2219-26. 2004
    ..Further, there is an interaction between Lp(a) and other risk factors for cardiovascular disease. The physiological role of Lp(a) is unknown, although a majority of studies implicate Lp(a) as a risk factor...
  8. ncbi request reprint Postprandial response to a physiologic caloric load in HIV-positive patients receiving protease inhibitor-based or nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    Asha Thomas-Geevarghese
    Department of Medicine and the General Clinical Research Center, Harlem Hospital Center and Columbia University, New York, NY, USA
    Am J Clin Nutr 82:146-54. 2005
    ..Features of the dyslipidemic pattern reported with the use of antiretroviral therapy predict enhanced postprandial lipemia, which is an emerging cardiovascular disease risk factor...
  9. pmc Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
    Kimber L Stanhope
    Department of Molecular Biosciences, UCD, Davis, California 95616, USA
    J Clin Invest 119:1322-34. 2009
    ..These data suggest that dietary fructose specifically increases DNL, promotes dyslipidemia, decreases insulin sensitivity, and increases visceral adiposity in overweight/obese adults...
  10. pmc Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitus
    Gissette Reyes-Soffer
    Departments of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    J Lipid Res 50:1901-9. 2009
    ..PP measurements of TG-rich lipoproteins do not predict the presence of CAD in individuals with DM...
  11. pmc Increased lipoprotein remnant cholesterol levels in HIV-positive patients during antiretroviral therapy
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, CA 95817, USA
    Atherosclerosis 198:192-7. 2008
    ..024, ANOVA). In conclusion, during HIV conditions, HAART resulted in a pro-atherogenic pattern with accumulation of remnant lipoproteins...
  12. pmc Postprandial metabolic responses to dietary glycemic index in hypercholesterolemic postmenopausal women
    Radhika N Bukkapatnam
    Department of Internal Medicine, University of California, Davis, CA 95616, USA
    Prev Cardiol 13:29-35. 2010
    ..The results suggest a postprandial impact of glycemic index on cardiovascular metabolic biomarkers in postmenopausal women and may have implications for dietary glycemic modification of cardiovascular risk in women...
  13. ncbi request reprint Postprandial lipemia and cardiovascular disease
    Dianne Hyson
    Department of Medicine, University of California, Davis, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
    Curr Atheroscler Rep 5:437-44. 2003
    ..Collectively, these data suggest that assessment and treatment of atherosclerosis should include parameters related to postprandial lipemia...
  14. ncbi request reprint Apolipoprotein E and diets: a case of gene-nutrient interaction?
    Jill Rubin
    Department of Medicine, Columbia University, New York, New York, USA
    Curr Opin Lipidol 13:25-32. 2002
    ..Studies directly designed to examine apolipoprotein E gene-nutrient interactions are needed...
  15. ncbi request reprint Fasting plasma insulin modulates lipid levels and particle sizes in 2- to 3-year-old children
    Steven Shea
    Division of General Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Obes Res 11:709-21. 2003
    ..We examined the relation of fasting insulin to lipid levels and lipid particle size in young healthy children...
  16. ncbi request reprint Treatment with high-dose simvastatin reduces secretion of apolipoprotein B-lipoproteins in patients with diabetic dyslipidemia
    Merle Myerson
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Lipid Res 46:2735-44. 2005
    ..Activation of PPARalpha could lead to increased hepatic oxidation of fatty acids and less synthesis of TG for VLDL assembly...
  17. pmc Relationship of postprandial nonesterified fatty acids, adipokines, and insulin across gender in human immunodeficiency virus-positive patients undergoing highly active antiretroviral therapy
    Guijing Lu
    Department of Medicine, University of California Davis, Sacramento, California 95817, USA
    Metab Syndr Relat Disord 7:199-204. 2009
    ..Metabolic derangements are common in human immunodeficiency virus (HIV)-positive subjects undergoing antiretroviral therapy, but little is known about postprandial conditions...
  18. pmc Usefulness of apolipoprotein B/apolipoprotein A-I ratio to predict coronary artery disease independent of the metabolic syndrome in African Americans
    Byambaa Enkhmaa
    Department of Medicine, University of California, Davis, Sacramento, USA
    Am J Cardiol 106:1264-9. 2010
    ..023). In conclusion, the apoB/apoA-I ratio differed across ethnicities and was associated with presence of the MS in both groups. Among African Americans, an elevated apoB/apoA-I ratio independently predicted a greater risk of CAD...
  19. ncbi request reprint Metabolic syndrome components in african-americans and European-american patients and its relation to coronary artery disease
    Erdembileg Anuurad
    Department of Medicine, University of California Davis, Davis, California, USA
    Am J Cardiol 100:830-4. 2007
    ..Although our findings may not be directly extrapolated to the population at large, they illustrate the importance of a high-risk metabolic environment as a cardiovascular risk factor...
  20. pmc Age as a modulator of inflammatory cardiovascular risk factors
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Arterioscler Thromb Vasc Biol 31:2151-6. 2011
    ..We assessed the relationship with age of inflammatory markers, representing (1) systemic (C-reactive protein, fibrinogen, and serum amyloid-A) and (2) vascular (lipoprotein-associated phospholipase A(2) and pentraxin-3) inflammation...
  21. pmc Association of Lp-PLA(2) activity with allele-specific Lp(a) levels in a bi-ethnic population
    Byambaa Enkhmaa
    Department of Medicine, University of California, Davis, CA, USA
    Atherosclerosis 211:526-30. 2010
    ..We investigated the association between Lp-PLA(2) activity and allele-specific apolipoprotein(a) [apo(a)] levels in a bi-ethnic population...
  22. doi request reprint Translational nutrition research at UC Davis--the key role of the Clinical and Translational Science Center
    Sidika Kasim-Karakas
    Department of Medicine, University of California Davis, Sacramento, California 95817, USA
    Ann N Y Acad Sci 1190:179-83. 2010
    ..The CTSC has impacted virtually every area and infrastructure resource involved in promoting clinical and translational research at our institution...
  23. pmc Human immunodeficiency virus and highly active antiretroviral therapy-associated metabolic disorders and risk factors for cardiovascular disease
    Erdembileg Anuurad
    Department of Medicine, University of California Davis, Sacramento, California 95817, USA
    Metab Syndr Relat Disord 7:401-10. 2009
    ....
  24. pmc ApoE and ApoC-I polymorphisms: association of genotype with cardiovascular disease phenotype in African Americans
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, CA, USA
    J Lipid Res 50:1472-8. 2009
    ..e., higher LDL cholesterol and apoB levels), compared with subjects without CAD. ApoC-I genotypes showed an ethnically distinct phenotype relationship with regard to CAD and CAD risk factors...
  25. ncbi request reprint Protective effect of apolipoprotein E2 on coronary artery disease in African Americans is mediated through lipoprotein cholesterol
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, CA, USA
    J Lipid Res 47:2475-81. 2006
    ....
  26. ncbi request reprint Lipoprotein(a) and thrombocytes: potential mechanisms underlying cardiovascular risk
    William Discepolo
    Department of Medicine, University of California Davis, 95817, USA
    Pathophysiol Haemost Thromb 35:314-21. 2006
    ..On balance, results indicate an effect by Lp(a) on platelet function and future studies focused on specific Lp(a) components, such as the role of apo(a) and of the LDL-like lipid moiety, are needed...
  27. ncbi request reprint The common insertional polymorphism in the APOC1 promoter is associated with serum apolipoprotein C-I levels in Hispanic children
    Neil S Shachter
    Department of Medicine, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Atherosclerosis 179:387-93. 2005
    ..These findings suggest that the mechanism of the previously described association with plasma TG is, at least in part, related to the correlation of the polymorphism with the level of expression of apoC-I...
  28. pmc Relation of Apo(a) size to carotid atherosclerosis in an elderly multiethnic population
    Furcy Paultre
    Department of Medicine, Columbia University, New York, NY 10032, USA
    Arterioscler Thromb Vasc Biol 22:141-6. 2002
    ..03). This association was significant for all men (P=0.03) and for white women (P=0.007). The results suggest that molecular properties of apo(a) are important in determining the atherogenicity of Lp(a)...

Research Grants22

  1. UC Davis Clinical and Translational Science Center
    Lars Berglund; Fiscal Year: 2007
    ..The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
  2. Regulation of Lipoprotein(a) Metabolism in Humans with Reference to Ethnicity
    Lars Berglund; Fiscal Year: 2009
    ..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..
  3. UC Davis Clinical and Translational Science Center
    Lars Berglund; Fiscal Year: 2007
    ..The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
  4. UC Davis Clinical and Translational Science Center
    Lars Berglund; Fiscal Year: 2007
    ..The UC Davis CTSCwill be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections. ..
  5. REGULATION OF LIPOPROTEIN (A) METABOLISM IN HUMANS
    Lars Berglund; Fiscal Year: 2003
    ..In addition, the investigators hope that their results with provide a framework for approaches to influence Lp(a) in clinical settings. ..
  6. LIPOPROTEIN AND ADIPOSE TISSUE METABOLISM IN HIV
    Lars Berglund; Fiscal Year: 2004
    ..abstract_text> ..
  7. Regulation of Lipoprotein(a) Metabolism in Humans with Reference to Ethnicity
    LARS F BERGLUND; Fiscal Year: 2010
    ..The proposal aims to understand which inherited factors affect Lipoprotein(a) and how this factor causes disease. The results will be important to design treatments. ..