Joseph R Berger

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. doi request reprint The neurologic complications of bariatric surgery
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA Electronic address
    Handb Clin Neurol 120:587-94. 2014
  2. ncbi request reprint The pathogenesis of progressive multifocal leukoencephalopathy
    Joseph R Berger
    Department of Neurology, University of Kentucky, 740 S Limestone St, Lexington, Kentucky 40536, USA
    Discov Med 12:495-503. 2011
  3. pmc Low prevalence of varicella zoster virus and herpes simplex virus type 2 in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy
    Chunmei C Wang
    Department of Oral Health Practice, University of Kentucky College of Medicine and College of Dentistry, Lexington, Kentucky 40536 0297, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:232-7. 2010
  4. pmc Monoclonal antibodies and progressive multifocal leukoencephalopathy
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    MAbs 1:583-9. 2009
  5. doi request reprint Disease-modifying drugs for multiple sclerosis and JC virus expression
    Craig S Miller
    College of Dentistry, University of Kentucky, Lexington, KY 40536 0284, USA
    J Neurovirol 18:411-5. 2012
  6. pmc JC virus antibody status underestimates infection rates
    Joseph R Berger
    Department of Neurology, College of Medicine, and, Lexington, KY
    Ann Neurol 74:84-90. 2013
  7. pmc High prevalence of multiple human herpesviruses in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy
    Craig S Miller
    Department of Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0297, USA
    J Clin Microbiol 44:2409-15. 2006
  8. doi request reprint A giant MS plaque mimicking PML during natalizumab treatment
    Cary Twyman
    Associates in Neurology, Lexington, KY 40536 0284, USA
    J Neurol Sci 291:110-3. 2010
  9. doi request reprint Pearls: neurologic complications of HIV/AIDS
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    Semin Neurol 30:66-70. 2010
  10. pmc PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section
    Joseph R Berger
    Department of Neurology, University of Kentucky, Lexington, USA
    Neurology 80:1430-8. 2013

Collaborators

Detail Information

Publications33

  1. doi request reprint The neurologic complications of bariatric surgery
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA Electronic address
    Handb Clin Neurol 120:587-94. 2014
    ..Their rapid diagnosis and appropriate treatment is essential to avoid long-term, irreversible consequences including, in some instances, death. ..
  2. ncbi request reprint The pathogenesis of progressive multifocal leukoencephalopathy
    Joseph R Berger
    Department of Neurology, University of Kentucky, 740 S Limestone St, Lexington, Kentucky 40536, USA
    Discov Med 12:495-503. 2011
    ....
  3. pmc Low prevalence of varicella zoster virus and herpes simplex virus type 2 in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy
    Chunmei C Wang
    Department of Oral Health Practice, University of Kentucky College of Medicine and College of Dentistry, Lexington, Kentucky 40536 0297, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:232-7. 2010
    ..The aim of this study was to investigate the prevalence and amounts of VZV and HSV-2 in the saliva of HIV-infected orally asymptomatic patients...
  4. pmc Monoclonal antibodies and progressive multifocal leukoencephalopathy
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    MAbs 1:583-9. 2009
    ..Based on our current understanding of the biology of JC virus and the pathogenesis of PML, we propose an explanation for the increased risk for PML that is observed with natalizumab and certain other monoclonal antibodies...
  5. doi request reprint Disease-modifying drugs for multiple sclerosis and JC virus expression
    Craig S Miller
    College of Dentistry, University of Kentucky, Lexington, KY 40536 0284, USA
    J Neurovirol 18:411-5. 2012
    ..The small number of patients on other therapies precluded meaningful comment about their effects. No obvious effect of the platform DMDs on JCV prevalence was observed even for the interferon-βs...
  6. pmc JC virus antibody status underestimates infection rates
    Joseph R Berger
    Department of Neurology, College of Medicine, and, Lexington, KY
    Ann Neurol 74:84-90. 2013
    ..JC virus (JCV) seropositivity is a risk factor for progressive multifocal leukoencephalopathy (PML) in patients on natalizumab. Accordingly, the JCV serological antibody test is of paramount importance in determining disease risk...
  7. pmc High prevalence of multiple human herpesviruses in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy
    Craig S Miller
    Department of Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536 0297, USA
    J Clin Microbiol 44:2409-15. 2006
    ..These findings suggest that saliva is a potential risk factor for the acquisition of multiple HHVs, and several host factors may function to accelerate HHV reactivation or replication in patients with HIV infection...
  8. doi request reprint A giant MS plaque mimicking PML during natalizumab treatment
    Cary Twyman
    Associates in Neurology, Lexington, KY 40536 0284, USA
    J Neurol Sci 291:110-3. 2010
    ..Distinguishing PML from MS may be very difficult in some instances. The frequency with which an aggressive demyelinating disorder due to MS occurs during treatment with natalizumab remains to be determined...
  9. doi request reprint Pearls: neurologic complications of HIV/AIDS
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA
    Semin Neurol 30:66-70. 2010
    ..Additionally, the complexity of evaluating the HIV-infected person with neurologic disease is increased by the relatively high frequency with which more than one disease concurrently affects the nervous system...
  10. pmc PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section
    Joseph R Berger
    Department of Neurology, University of Kentucky, Lexington, USA
    Neurology 80:1430-8. 2013
    ..To establish criteria for the diagnosis of progressive multifocal leukoencephalopathy (PML)...
  11. doi request reprint Coxsackie B meningoencephalitis in a patient with acquired immunodeficiency syndrome and a multiple sclerosis-like illness
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA
    J Neurovirol 15:282-7. 2009
    ..This is the first case report, to the best of our knowledge, of an enteroviral meningoencephalitis complicating human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)...
  12. doi request reprint Progressive multifocal leukoencephalopathy and relapsing-remitting multiple sclerosis: a comparative study
    Aaron Boster
    Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Arch Neurol 66:593-9. 2009
    ..To identify clinical and magnetic resonance imaging (MRI) features that distinguish progressive multifocal leukoencephalopathy (PML) from relapsing-remitting multiple sclerosis (RRMS)...
  13. doi request reprint Opportunistic infections and other risks with newer multiple sclerosis therapies
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA
    Ann Neurol 65:367-77. 2009
    ..Determining the actual risk frequency for many of these complications will likely require careful postmarketing surveillance...
  14. ncbi request reprint Cystinosis of the brain and spinal cord with associated vasculopathy
    Joseph R Berger
    Department of Neurology, The University of Kentucky College of Medicine, Lexington, Kentucky 40536 0284, USA
    J Neurol Sci 284:182-5. 2009
    ..As more patients with cystinosis experience long term survival, there will likely be an increased frequency of CNS disease...
  15. ncbi request reprint Progressive multifocal leukoencephalopathy
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic L 445, 740 S Limestone Street, Lexington, KY 40536 0284, USA
    Curr Neurol Neurosci Rep 7:461-9. 2007
    ..Treatment directed against the JC virus has been unhelpful, but an increased understanding of disease pathogenesis may result in effective therapeutic strategies...
  16. ncbi request reprint Functional improvement and symptom management in multiple sclerosis: clinical efficacy of current therapies
    Joseph R Berger
    University of Kentucky, 740 S Limestone St, Lexington, KY 40536, USA
    Am J Manag Care 17:S146-53. 2011
    ..By improving walking in some patients with MS, the effects of dalfampridine may complement those of DMTs and address the stated priorities of many patients...
  17. doi request reprint Primary lateral sclerosis with HIV-1 infection
    Ashok Verma
    Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA
    Neurology 70:575-7. 2008
  18. doi request reprint Neurological complications of herpes simplex virus type 2 infection
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic, Room L 445, 740 S Limestone St, Lexington, KY 40536 0284, USA
    Arch Neurol 65:596-600. 2008
    ..Despite a 50% genetic homology between HSV-1 and HSV-2, there are significant differences in the clinical manifestations of these 2 viruses. We herein review the neurological complications of HSV-2 infection...
  19. ncbi request reprint The neurological complications of bariatric surgery
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington 40536 0284, USA
    Arch Neurol 61:1185-9. 2004
  20. pmc Frequency and phenotype of JC virus-specific CD8+ T lymphocytes in the peripheral blood of patients with progressive multifocal leukoencephalopathy
    Marco A Lima
    Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    J Virol 81:3361-8. 2007
    ..Immunotherapies aiming at increasing the cellular immune response against JCV may be valuable in the treatment of HIV+ individuals with PML...
  21. ncbi request reprint Natalizumab
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic, Lexington, Kentucky 40536 0284, USA
    Drugs Today (Barc) 42:639-55. 2006
    ..Postmarketing surveillance studies should answer this and other questions related to the use of natalizumab...
  22. pmc Expression of miR-15/107 family microRNAs in human tissues and cultured rat brain cells
    Wang Xia Wang
    Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA
    Genomics Proteomics Bioinformatics 12:19-30. 2014
    ..In summary, we provide a detailed study of the tissue and cell type-specific expression profile of this highly expressed and phylogenetically conserved family of miRNA genes. ..
  23. doi request reprint Isolated Histoplasma capsulatum meningoencephalitis in an immunocompetent child
    Zachary D Threlkeld
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40536 0281, USA
    J Child Neurol 27:532-5. 2012
    ..We describe an immunocompetent 13-year-old girl with atypical symptoms and unusual radiologic findings due to laboratory-confirmed histoplasma meningoencephalitis. She responded well to antifungal therapy...
  24. ncbi request reprint The HIV Dementia Scale: predictive power in mild dementia and HAART
    Kara Anne Bottiggi
    Graduate Center for Gerontology, College of Public Health, University of Kentucky, KY, USA
    J Neurol Sci 260:11-5. 2007
    ..With the advent of highly active antiretroviral therapy (HAART), the use of sensitive and efficient screening tests for HIV-D continue to be needed for identifying individuals who develop this disorder...
  25. doi request reprint Progressive multifocal leukoencephalopathy and newer biological agents
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky 40536 0284, USA
    Drug Saf 33:969-83. 2010
    ..A biologically plausible explanation for the increased risk of PML will be proposed, as well as potential strategies for mitigating disease risk...
  26. ncbi request reprint Stroke in HIV infection and AIDS
    Michael R Dobbs
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA
    Expert Rev Cardiovasc Ther 7:1263-71. 2009
    ..Selecting the appropriate therapy for treating stroke in the HIV-infected patient is dependent on diagnostic rigor in identifying its underlying etiology...
  27. ncbi request reprint Progressive multifocal leukoencephalopathy in multiple sclerosis
    Joshua J Chalkley
    Department of Neurology, University of Kentucky College of Medicine, 740 S Limestone St, Room L 445, Lexington, KY, 40536 0284, USA
    Curr Neurol Neurosci Rep 13:408. 2013
    ..Risk mitigation strategies have been developed for the natalizumab-associated PML, which has been convincingly demonstrated to be linked to duration of therapy, JC virus seropositivity, and the prior use of immunosuppressive agents. ..
  28. doi request reprint Fatigue heralding multiple sclerosis
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, KY, USA
    Mult Scler 19:1526-32. 2013
    ..Fatigue is a common symptom in multiple sclerosis (MS) and is an important determinant of overall well-being and disability...
  29. ncbi request reprint Progressive multifocal leukoencephalopathy: lessons from AIDS and natalizumab
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Lexington, 40536, USA
    Neurol Res 28:299-305. 2006
    ..Studies in these populations will be invaluable in understanding the mechanisms of disease pathogenesis...
  30. doi request reprint The clinical features of PML
    Joseph R Berger
    Department of Neurology, University of Kentucky Medical Center, KY Clinic Wing D L445, Lexington, KY 40536 0284, USA
    Cleve Clin J Med 78:S8-12. 2011
    ..With immune reconstitution, the prognosis of PML has improved markedly...
  31. doi request reprint Neurologic consequences of autoimmune polyglandular syndrome type 1
    Joseph R Berger
    Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic L 445, 740 S Limestone Street, Lexington, KY 40536 0284, USA
    Neurology 70:2248-51. 2008
    ..The neurologic complications of this disorder have not been well characterized...
  32. ncbi request reprint JC virus detection in bodily fluids: clues to transmission
    Joseph R Berger
    Department of Neurology, College of Medicine, University of Kentucky, Lexington, KY 40536 0284, USA
    Clin Infect Dis 43:e9-12. 2006
    ....
  33. ncbi request reprint Complications of immunosuppressive/immunomodulatory therapy in neurological diseases
    Avindra Nath
    Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic L 445, 740 S Limestone Street, Lexington, KY, 40536 0284, USA
    Curr Treat Options Neurol 14:241-55. 2012
    ..For a number of opportunistic infectious disorders, particularly some viral and fungal diseases, antimicrobial therapy remains inadequate...