Andrew J Berger

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Raman microspectroscopy for species identification and mapping within bacterial biofilms
    Brooke D Beier
    The Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14627, USA
    AMB Express 2:35. 2012
  2. doi request reprint Method for automated background subtraction from Raman spectra containing known contaminants
    Brooke D Beier
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Analyst 134:1198-202. 2009
  3. ncbi request reprint Correction method for absorption-dependent signal enhancement by a liquid-core optical fiber
    Dahu Qi
    University of Rochester, Rochester, New York 14627, USA
    Appl Opt 45:489-94. 2006
  4. doi request reprint Two-detector Corrected Near Infrared Spectroscopy (C-NIRS) detects hemodynamic activation responses more robustly than single-detector NIRS
    Rolf B Saager
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Neuroimage 55:1679-85. 2011
  5. pmc Identification of different bacterial species in biofilms using confocal Raman microscopy
    Brooke D Beier
    University of Rochester, The Institute of Optics, Wilmot Building, Rochester, NY14627, USA
    J Biomed Opt 15:066001. 2010
  6. ncbi request reprint Chemical concentration measurement in blood serum and urine samples using liquid-core optical fiber Raman spectroscopy
    Dahu Qi
    The Institute of Optics, University of Rochester, New York 14627, USA
    Appl Opt 46:1726-34. 2007
  7. ncbi request reprint Quantitative concentration measurements of creatinine dissolved in water and urine using Raman spectroscopy and a liquid core optical fiber
    Dahu Qi
    University of Rochester, The Institute of Optics, Department of Physics and Astronomy, Rochester, New York 14627, USA
    J Biomed Opt 10:031115. 2005
  8. ncbi request reprint Quantitative analysis of Raman signal enhancement from aqueous samples in liquid core optical fibers
    Dahu Qi
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    Appl Spectrosc 58:1165-71. 2004
  9. ncbi request reprint Direct characterization and removal of interfering absorption trends in two-layer turbid media
    Rolf B Saager
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    J Opt Soc Am A Opt Image Sci Vis 22:1874-82. 2005
  10. pmc Raman spectroscopic measurement of relative concentrations in mixtures of oral bacteria
    Qingyuan Zhu
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Appl Spectrosc 61:1233-7. 2007

Research Grants

  1. Raman spectroscopy of bacteria in oral plaques
    ANDREW BERGER; Fiscal Year: 2006

Collaborators

  • Brooke D Beier
  • Dahu Qi
  • Rolf B Saager
  • Zachary J Smith
  • Qingyuan Zhu
  • Obrad R Scepanovic
  • Robert G Quivey
  • John W McMurdy
  • Nicole L Telleri
  • Kate L Bechtel
  • Wei Chuan Shih
  • Michael S Feld
  • Abigail S Haka
  • Tae Woong Koo

Detail Information

Publications15

  1. pmc Raman microspectroscopy for species identification and mapping within bacterial biofilms
    Brooke D Beier
    The Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14627, USA
    AMB Express 2:35. 2012
    ..We then used the algorithm successfully both to detect the presence of two species in mixed biofilms and to create spatial maps within these biofilms...
  2. doi request reprint Method for automated background subtraction from Raman spectra containing known contaminants
    Brooke D Beier
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Analyst 134:1198-202. 2009
    ..An automated method for the removal of broad and/or moderately featured background signal is described. In addition to simulations, the method has been applied to spectra from biofilms of Streptococcus mutans...
  3. ncbi request reprint Correction method for absorption-dependent signal enhancement by a liquid-core optical fiber
    Dahu Qi
    University of Rochester, Rochester, New York 14627, USA
    Appl Opt 45:489-94. 2006
    ..This correction method should be important for LCOF-based Raman spectroscopy of sample sets with variable absorption coefficients, such as urine and blood serum from multiple patients...
  4. doi request reprint Two-detector Corrected Near Infrared Spectroscopy (C-NIRS) detects hemodynamic activation responses more robustly than single-detector NIRS
    Rolf B Saager
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Neuroimage 55:1679-85. 2011
    ..Parallel insights regarding deoxyhemoglobin trends could not be drawn from this data set but should be attainable in future studies with higher signal to noise ratios...
  5. pmc Identification of different bacterial species in biofilms using confocal Raman microscopy
    Brooke D Beier
    University of Rochester, The Institute of Optics, Wilmot Building, Rochester, NY14627, USA
    J Biomed Opt 15:066001. 2010
    ..This combination of spatial resolution and predication accuracy should be suitable for forming images of species distributions within intact two-species biofilms...
  6. ncbi request reprint Chemical concentration measurement in blood serum and urine samples using liquid-core optical fiber Raman spectroscopy
    Dahu Qi
    The Institute of Optics, University of Rochester, New York 14627, USA
    Appl Opt 46:1726-34. 2007
    ..Using absorption data to normalize the LCOF enhancement made the results more accurate. The experimental geometry is well suited for high-volume and automated chemical analysis of clear biofluids...
  7. ncbi request reprint Quantitative concentration measurements of creatinine dissolved in water and urine using Raman spectroscopy and a liquid core optical fiber
    Dahu Qi
    University of Rochester, The Institute of Optics, Department of Physics and Astronomy, Rochester, New York 14627, USA
    J Biomed Opt 10:031115. 2005
    ..These results indicate that Raman spectroscopy with these Teflon-AF LCOFs is stable enough for quantitative concentration predictions, accurate to a few percent of the concentration range spanned...
  8. ncbi request reprint Quantitative analysis of Raman signal enhancement from aqueous samples in liquid core optical fibers
    Dahu Qi
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    Appl Spectrosc 58:1165-71. 2004
    ..In particular, the model shows that absorption and scattering losses affect the enhancement factor in different ways...
  9. ncbi request reprint Direct characterization and removal of interfering absorption trends in two-layer turbid media
    Rolf B Saager
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    J Opt Soc Am A Opt Image Sci Vis 22:1874-82. 2005
    ..An analytical approximation for the least-squares coefficient provides physical insight into the nature of errors and suggests ways to reduce them...
  10. pmc Raman spectroscopic measurement of relative concentrations in mixtures of oral bacteria
    Qingyuan Zhu
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Appl Spectrosc 61:1233-7. 2007
    ..07. These results suggest that near-infrared Raman spectroscopy is potentially useful in quantification of microbial mixtures in general and oral plaques in particular...
  11. doi request reprint Determination of uncertainty in parameters extracted from single spectroscopic measurements
    Obrad R Scepanovic
    Massachusetts Institute of Technology, G R Harrison Spectroscopy Laboratory, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 12:064012. 2007
    ..These results are intended to encourage the widespread use of uncertainty analysis in the biomedical optics community...
  12. ncbi request reprint Integrated Raman- and angular-scattering microscopy
    Zachary J Smith
    The Institute of Optics, University of Rochester, Rochester, NY 14627, USA
    Opt Lett 33:714-6. 2008
    ..The microscope system exhibits 3 nm precision in predicting sphere diameters, while simultaneously yielding high-quality Raman signals. Applications to single cell analysis are envisioned...
  13. ncbi request reprint Surface-sensitive polarized Raman spectroscopy of biological tissue
    Zachary J Smith
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    Opt Lett 30:1363-5. 2005
    ..We employ detection of orthogonal polarization states to generate a Raman spectrum of only the superficial layer by combining the orthogonal signals...
  14. ncbi request reprint Measurement of bacterial concentration fractions in polymicrobial mixtures by Raman microspectroscopy
    Qingyuan Zhu
    University of Rochester, Department of Electrical Engineering and The Institute of Optics, Rochester, NY 14627, USA
    J Biomed Opt 9:1182-6. 2004
    ..mutans. Samples with and without salivary proteins are predicted with equal accuracy. This result shows the potential of Raman spectroscopy for analyzing mixed populations of bacteria, such as those that occur in oral plaques...
  15. ncbi request reprint Raman spectroscopy-based creatinine measurement in urine samples from a multipatient population
    John W McMurdy
    The Institute of Optics, University of Rochester, Rochester, New York 14627, USA
    Appl Spectrosc 57:522-5. 2003
    ..Because most assays in urine require creatinine concentration in order to correct for fluctuations in water content, measurement of creatinine is the first step towards more extensive Raman-based urinalysis...

Research Grants1

  1. Raman spectroscopy of bacteria in oral plaques
    ANDREW BERGER; Fiscal Year: 2006
    ..In addition, the methodologies developed during this investigation will be broadly applicable to other problems requiring quantitative discrimination between two or more similar organisms in biological mixtures. ..