N C Berchtold

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript
    N C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, 1226 Gillespie Building, Irvine, CA 92697 4540, USA
    Brain Res Mol Brain Res 71:11-22. 1999
  2. ncbi request reprint Exercise: a behavioral intervention to enhance brain health and plasticity
    Carl W Cotman
    Institute for Brain Aging and Dementia, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4540, USA
    Trends Neurosci 25:295-301. 2002
  3. pmc Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes
    Miklós Sárvári
    Laboratory of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, Budapest 1083, Hungary
    J Neuroinflammation 9:264. 2012
  4. pmc Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
    David H Cribbs
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 1226 Gillespie NRF, Irvine, CA 92697, USA
    J Neuroinflammation 9:179. 2012
  5. doi request reprint Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
    Nicole C Berchtold
    Institute for Mental Impairments and Neurological Disorders MIND, University of California Irvine, Irvine, CA, USA
    Neurobiol Aging 34:1653-61. 2013
  6. pmc Exercise and time-dependent benefits to learning and memory
    N C Berchtold
    Institute for Memory Impairment and Neurobiological Disorders, University of California, Irvine, CA 92697 4545, USA
    Neuroscience 167:588-97. 2010
  7. ncbi request reprint Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Neuroscience 133:853-61. 2005
  8. ncbi request reprint Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum
    Nicole C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, California, 92697 4540, USA
    J Neurosci Res 68:511-21. 2002
  9. ncbi request reprint Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Eur J Neurosci 14:1992-2002. 2001
  10. ncbi request reprint Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Neurosci Lett 353:95-8. 2003

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript
    N C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, 1226 Gillespie Building, Irvine, CA 92697 4540, USA
    Brain Res Mol Brain Res 71:11-22. 1999
    ....
  2. ncbi request reprint Exercise: a behavioral intervention to enhance brain health and plasticity
    Carl W Cotman
    Institute for Brain Aging and Dementia, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4540, USA
    Trends Neurosci 25:295-301. 2002
    ..Thus, exercise could provide a simple means to maintain brain function and promote brain plasticity...
  3. pmc Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes
    Miklós Sárvári
    Laboratory of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, Budapest 1083, Hungary
    J Neuroinflammation 9:264. 2012
    ..Here, we explored the impact of menopause on the microglia phenotype capitalizing on the differential expression of macrophage-associated genes in quiescent and activated microglia...
  4. pmc Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
    David H Cribbs
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 1226 Gillespie NRF, Irvine, CA 92697, USA
    J Neuroinflammation 9:179. 2012
    ..This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer's disease (AD)...
  5. doi request reprint Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
    Nicole C Berchtold
    Institute for Mental Impairments and Neurological Disorders MIND, University of California Irvine, Irvine, CA, USA
    Neurobiol Aging 34:1653-61. 2013
    ..The widespread declines in synaptic gene expression in normal aging suggests that function of existing synapses might be impaired, and that a common set of synaptic genes are vulnerable to change in aging and AD...
  6. pmc Exercise and time-dependent benefits to learning and memory
    N C Berchtold
    Institute for Memory Impairment and Neurobiological Disorders, University of California, Irvine, CA 92697 4545, USA
    Neuroscience 167:588-97. 2010
    ....
  7. ncbi request reprint Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Neuroscience 133:853-61. 2005
    ..These findings are clinically important because they provide guidelines for optimizing the design of exercise and rehabilitation programs, in order to promote hippocampal function...
  8. ncbi request reprint Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum
    Nicole C Berchtold
    Institute for Brain Aging and Dementia, University of California, Irvine, California, 92697 4540, USA
    J Neurosci Res 68:511-21. 2002
    ..These results are discussed in relation to their implications for aging and Alzheimer's disease...
  9. ncbi request reprint Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
    N C Berchtold
    Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
    Eur J Neurosci 14:1992-2002. 2001
    ..The interaction of estrogen, physical activity and hippocampal BDNF is likely to be an important issue for maintenance of brain health, plasticity and general well-being, particularly in women...
  10. ncbi request reprint Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in rats
    J Patrick Kesslak
    Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
    Neurosci Lett 353:95-8. 2003
    ..Increases in BDNF and NMDA activity may be significant components in learning and memory, and modulation of these systems may be beneficial for developing strategies to improve cognitive function...
  11. ncbi request reprint Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion
    Martin Ramsden
    Andrus Gerontology Center, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089 0191, USA
    Brain Res 971:239-44. 2003
    ....
  12. ncbi request reprint Exercise builds brain health: key roles of growth factor cascades and inflammation
    Carl W Cotman
    University of California, Irvine Institute for Brain Aging and Dementia, 1113 Gillespie Building, Irvine, CA 92617 4540, USA
    Trends Neurosci 30:464-72. 2007
    ..Thus, through regulation of growth factors and reduction of peripheral and central risk factors, exercise ensures successful brain function...
  13. pmc Voluntary running attenuates age-related deficits following SCI
    Monica M Siegenthaler
    Reeve Irvine Research Center, Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 4292, USA
    Exp Neurol 210:207-16. 2008
    ..Importantly, our data indicate that exercise attenuates these age-related deficits following SCI...