Research Topics
| N C BerchtoldSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcriptN C Berchtold
Institute for Brain Aging and Dementia, University of California, Irvine, 1226 Gillespie Building, Irvine, CA 92697 4540, USA
Brain Res Mol Brain Res 71:11-22. 1999....
Exercise: a behavioral intervention to enhance brain health and plasticityCarl W Cotman
Institute for Brain Aging and Dementia, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4540, USA
Trends Neurosci 25:295-301. 2002..Thus, exercise could provide a simple means to maintain brain function and promote brain plasticity...
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's diseaseNicole C Berchtold
Institute for Mental Impairments and Neurological Disorders MIND, University of California Irvine, Irvine, CA, USA
Neurobiol Aging 34:1653-61. 2013..The widespread declines in synaptic gene expression in normal aging suggests that function of existing synapses might be impaired, and that a common set of synaptic genes are vulnerable to change in aging and AD...
Exercise and time-dependent benefits to learning and memoryN C Berchtold
Institute for Memory Impairment and Neurobiological Disorders, University of California, Irvine, CA 92697 4545, USA
Neuroscience 167:588-97. 2010....
Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampusN C Berchtold
Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
Neuroscience 133:853-61. 2005..These findings are clinically important because they provide guidelines for optimizing the design of exercise and rehabilitation programs, in order to promote hippocampal function...
Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septumNicole C Berchtold
Institute for Brain Aging and Dementia, University of California, Irvine, California, 92697 4540, USA
J Neurosci Res 68:511-21. 2002..These results are discussed in relation to their implications for aging and Alzheimer's disease...
Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampusN C Berchtold
Institute for Brain Aging and Dementia, 1226 Gillespie Neuroscience Facility, University of California, Irvine, CA 92697 4540, USA
Eur J Neurosci 14:1992-2002. 2001..The interaction of estrogen, physical activity and hippocampal BDNF is likely to be an important issue for maintenance of brain health, plasticity and general well-being, particularly in women...
Exercise increases the vulnerability of rat hippocampal neurons to kainate lesionMartin Ramsden
Andrus Gerontology Center, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089-0191, USA
Brain Res 971:239-44. 2003....
Exercise builds brain health: key roles of growth factor cascades and inflammationCarl W Cotman
University of California, Irvine Institute for Brain Aging and Dementia, 1113 Gillespie Building, Irvine, CA 92617 4540, USA
Trends Neurosci 30:464-72. 2007..Thus, through regulation of growth factors and reduction of peripheral and central risk factors, exercise ensures successful brain function...
Spatial learning is delayed and brain-derived neurotrophic factor mRNA expression inhibited by administration of MK-801 in ratsJ Patrick Kesslak
Institute for Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
Neurosci Lett 353:95-8. 2003..Increases in BDNF and NMDA activity may be significant components in learning and memory, and modulation of these systems may be beneficial for developing strategies to improve cognitive function...
Voluntary running attenuates age-related deficits following SCIMonica M Siegenthaler
Reeve Irvine Research Center, Department of Anatomy and Neurobiology, School of Medicine, University of California at Irvine, Irvine, CA 92697 4292, USA
Exp Neurol 210:207-16. 2008..Importantly, our data indicate that exercise attenuates these age-related deficits following SCI...
