Søren M Bentzen

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Whole brain radiotherapy with hippocampal avoidance and simultaneously integrated brain metastases boost: a planning study
    Alonso N Gutierrez
    Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:589-97. 2007
  2. doi request reprint Bioeffect modeling and equieffective dose concepts in radiation oncology--terminology, quantities and units
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Radiother Oncol 105:266-8. 2012
  3. pmc A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose
    Anthony J Chalmers
    Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
    Theor Biol Med Model 4:25. 2007
  4. doi request reprint Multiple biomarker tissue microarrays: bioinformatics and practical approaches
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, K4 316 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA
    Cancer Metastasis Rev 27:481-94. 2008
  5. ncbi request reprint Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, K4 316 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792, USA
    Nat Rev Cancer 6:702-13. 2006
  6. ncbi request reprint Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, K4 316 Clinical Sciences Center, Madison, WI 53792, USA
    Nat Clin Pract Oncol 4:172-80. 2007
  7. ncbi request reprint Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project
    Søren M Bentzen
    Gray Cancer Institute and the Cancer Centre, Mount Vernon Hospital, Northwood, UK
    Radiother Oncol 75:355-65. 2005
  8. ncbi request reprint Increasing toxicity in nonoperative head and neck cancer treatment: investigations and interventions
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:S79-82. 2007
  9. ncbi request reprint From cellular to high-throughput predictive assays in radiation oncology: challenges and opportunities
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Semin Radiat Oncol 18:75-88. 2008
  10. pmc Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription
    Søren M Bentzen
    Departments of Human Oncology, Medical Physics, Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792, USA
    Semin Radiat Oncol 21:101-10. 2011

Detail Information

Publications56

  1. pmc Whole brain radiotherapy with hippocampal avoidance and simultaneously integrated brain metastases boost: a planning study
    Alonso N Gutierrez
    Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:589-97. 2007
    ....
  2. doi request reprint Bioeffect modeling and equieffective dose concepts in radiation oncology--terminology, quantities and units
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Radiother Oncol 105:266-8. 2012
    ....
  3. pmc A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose
    Anthony J Chalmers
    Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
    Theor Biol Med Model 4:25. 2007
    ..The aim of this study was to develop and evaluate a modelling strategy by which radiation dose dependent effects of DNA repair inhibitors on clonogenic survival might be identified and their significance assessed...
  4. doi request reprint Multiple biomarker tissue microarrays: bioinformatics and practical approaches
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, K4 316 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA
    Cancer Metastasis Rev 27:481-94. 2008
    ..This technology and the practical issues involved in designing TMAs for translational research are reviewed. A main field of application of TMAs is in the search for predictive and prognostic markers in specific types of cancer...
  5. ncbi request reprint Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, K4 316 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792, USA
    Nat Rev Cancer 6:702-13. 2006
    ..This stimulates research into new pharmacological strategies for preventing or reducing the side effects of radiation therapy...
  6. ncbi request reprint Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, K4 316 Clinical Sciences Center, Madison, WI 53792, USA
    Nat Clin Pract Oncol 4:172-80. 2007
    ..Further clinical progress in this field will require hypothesis-driven trials to ensure efficient identification of treatments with the most favorable risk:benefit ratio...
  7. ncbi request reprint Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project
    Søren M Bentzen
    Gray Cancer Institute and the Cancer Centre, Mount Vernon Hospital, Northwood, UK
    Radiother Oncol 75:355-65. 2005
    ..In this report, we combine the best available evidence on the indications for RT with national epidemiological data to arrive at estimates for the appropriate level of RT infrastructure in the 25 EU countries...
  8. ncbi request reprint Increasing toxicity in nonoperative head and neck cancer treatment: investigations and interventions
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:S79-82. 2007
  9. ncbi request reprint From cellular to high-throughput predictive assays in radiation oncology: challenges and opportunities
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Semin Radiat Oncol 18:75-88. 2008
    ....
  10. pmc Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription
    Søren M Bentzen
    Departments of Human Oncology, Medical Physics, Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI 53792, USA
    Semin Radiat Oncol 21:101-10. 2011
    ..Challenges and research priorities in this exciting research field are defined and a possible design for a randomized clinical trial of dose painting is presented...
  11. pmc Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 76:S3-9. 2010
    ..Research priorities for the next 5-10 years are proposed...
  12. pmc Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 76:S145-50. 2010
    ..The importance of adjusting for radiation dose distribution in normal tissue biomarker studies is underlined. Finally, research priorities in this field are identified and discussed...
  13. ncbi request reprint The alpha/beta ratio for prostate cancer: what is it, really?
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin Medical School, WI 53792, USA
    Radiother Oncol 76:1-3. 2005
    ..Taken together, the outcomes of these two studies still favor a high fractionation sensitivity of prostate cancer...
  14. ncbi request reprint Steepness of the radiation dose-response curve for dose-per-fraction escalation keeping the number of fractions fixed
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin Medical School, Madison, Wisconsin, USA
    Acta Oncol 44:825-8. 2005
    ..Some implications of this formulation for non-uniform dose distributions delivered using 3D conformal radiotherapy or intensity modulated radiotherapy (IMRT) are briefly discussed...
  15. ncbi request reprint Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial
    Søren M Bentzen
    Gray Cancer Institute, The Cancer Centre, and Department of Pathology, Mount Vernon Hospital, United Kingdom
    J Clin Oncol 23:5560-7. 2005
    ....
  16. pmc Intensity-modulated radiotherapy might increase pneumonitis risk relative to three-dimensional conformal radiotherapy in patients receiving combined chemotherapy and radiotherapy: a modeling study of dose dumping
    Ivan S Vogelius
    Department of Oncology, Vejle Sygehus, Vejle, Denmark
    Int J Radiat Oncol Biol Phys 80:893-9. 2011
    ..To model the possible interaction between cytotoxic chemotherapy and the radiation dose distribution with respect to the risk of radiation pneumonitis...
  17. ncbi request reprint Theragnostic imaging for radiation oncology: dose-painting by numbers
    Søren M Bentzen
    University of Wisconsin Medical School, Department of Human Oncology, K4 316 Clinical Sciences Center, WI 53792, USA
    Lancet Oncol 6:112-7. 2005
    ..This approach will revolutionise the way that radiotherapy is prescribed and planned and, at least in theory, will improve the therapeutic outcome in terms of local tumour control and side-effects to unaffected tissue...
  18. pmc Dose-limiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer
    Donald M Cannon
    Donald M Cannon, Pranshu Mohindra, Søren M Bentzen, Anne M Traynor, Richard J Chappell, University of Wisconsin School of Medicine and Public Health, Madison, WI Minesh P Mehta, University of Maryland, Baltimore, MD Jarrod B Adkison, Southeast Alabama Medical Center, Dothan, AL Deepak Khuntia, Varian Medical Systems, Palo Alto, CA Wolfgang A Tomé, Albert Einstein College of Medicine, Bronx, NY George M Cannon, Intermountain Medical Center, Salt Lake City, UT Ranjini Tolakanahalli, Juravinski Cancer Center, Hamilton, Canada
    J Clin Oncol 31:4343-8. 2013
    ..The maximum-tolerated dose (MTD) with dose-escalated hypofractionation has not been adequately defined...
  19. ncbi request reprint Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy
    Francesca M Buffa
    Department of Pathology, Mount Vernon Hospital, London, United Kingdom
    Clin Cancer Res 10:3745-54. 2004
    ....
  20. ncbi request reprint Locoregional recurrence following accelerated partial breast irradiation for early-stage invasive breast cancer: significance of estrogen receptor status and other pathological variables
    Donald M Cannon
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Ann Surg Oncol 20:3446-52. 2013
    ..Published findings to date have not been consistent. More data are needed as these risk factors continue to be defined...
  21. ncbi request reprint Pre-treatment proliferation and the outcome of conventional and accelerated radiotherapy
    George D Wilson
    Gray Cancer Institute, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, UK
    Eur J Cancer 42:363-71. 2006
    ..005). The data presented in this study do not support that a high pre-treatment Ki-67 is associated with a therapeutic benefit from accelerated radiotherapy...
  22. ncbi request reprint Molecular biomarkers and site of first recurrence after radiotherapy for head and neck cancer
    Ozlem U Ataman
    Gray Cancer Institute, Group for Human Cancer Biology and Informatics, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, UK
    Eur J Cancer 40:2734-41. 2004
    ..Risks of T-, N- and M-failures could be estimated for individual patients. Competing risks analysis of failure sites allows the rational selection of patients for more aggressive loco-regional or systemic therapy...
  23. ncbi request reprint An immunohistochemical assessment of hypoxia in prostate carcinoma using pimonidazole: implications for radioresistance
    Dawn M Carnell
    Marie Curie Research Wing, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    Int J Radiat Oncol Biol Phys 65:91-9. 2006
    ..To investigate the presence of hypoxia in human prostate carcinoma by using pimonidazole immunohistochemical labeling in radical prostatectomy specimens...
  24. ncbi request reprint Hypofractionation does not increase radiation pneumonitis risk with modern conformal radiation delivery techniques
    Ivan S Vogelius
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Acta Oncol 49:1052-7. 2010
    ..To study the interaction between radiation dose distribution and hypofractionated radiotherapy with respect to the risk of radiation pneumonitis (RP) estimated from normal tissue complication probability (NTCP) models...
  25. ncbi request reprint Compliance to the prescribed dose and overall treatment time in five randomized clinical trials of altered fractionation in radiotherapy for head-and-neck carcinomas
    Azza A Khalil
    Gray Cancer Institute, Mount Vernon Hospital, Northwood, United Kingdom
    Int J Radiat Oncol Biol Phys 55:568-75. 2003
    ..To investigate compliance to the prescribed dose-fractionation schedule in five randomized controlled trials of altered fractionation in radiotherapy for head-and-neck carcinoma...
  26. pmc Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modeling
    Stephen R Bowen
    University of Wisconsin School of Medicine and Public Health, Department of Medical Physics, Madison, WI 53706, USA
    Nucl Med Biol 38:771-80. 2011
    ..Differences in imaged uptake of two common hypoxia radiotracers, [(61)Cu]Cu-ATSM and [(18)F]FMISO, were characterized via computational modeling to address these challenges...
  27. pmc Severe late toxicities following concomitant chemoradiotherapy compared to radiotherapy alone in cervical cancer: an inter-era analysis
    Vinai Gondi
    Department of Human Oncology, University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin 53792, USA
    Int J Radiat Oncol Biol Phys 84:973-82. 2012
    ..To compare rates of severe late toxicities following concomitant chemoradiotherapy and radiotherapy alone for cervical cancer...
  28. pmc Comprehensive IMRT plus weekly cisplatin for advanced head and neck cancer: the University of Wisconsin experience
    Anne M Traynor
    Section of Hematology and Medical Oncology, University of Wisconsin, Paul P Carbone Comprehensive Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Head Neck 32:599-606. 2010
    ....
  29. pmc Spatially resolved regression analysis of pre-treatment FDG, FLT and Cu-ATSM PET from post-treatment FDG PET: an exploratory study
    Stephen R Bowen
    University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Radiother Oncol 105:41-8. 2012
    ..To quantify associations between pre-radiotherapy and post-radiotherapy PET parameters via spatially resolved regression...
  30. pmc Estimated risk of perihippocampal disease progression after hippocampal avoidance during whole-brain radiotherapy: safety profile for RTOG 0933
    Vinai Gondi
    Department of Human Oncology, University of Wisconsin Comprehensive Cancer Center, Madison, WI 53792, USA
    Radiother Oncol 95:327-31. 2010
    ..By quantifying baseline incidence of perihippocampal or hippocampal metastasis, we sought to estimate the risk of developing metastases in the hippocampal avoidance region (the hippocampus plus 5mm margin)...
  31. ncbi request reprint Deterministic rather than stochastic factors explain most of the variation in the expression of skin telangiectasia after radiotherapy
    Akmal Safwat
    Group for Biostatistics in Oncology, Gray Laboratory, Northwood, Middlesex, UK
    Int J Radiat Oncol Biol Phys 52:198-204. 2002
    ..A better understanding of this individual variation may provide valuable insights into the pathogenesis of radiation damage and the prospects of predicting the outcome...
  32. ncbi request reprint Dose painting and theragnostic imaging: towards the prescription, planning and delivery of biologically targeted dose distributions in external beam radiation oncology
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, USA
    Cancer Treat Res 139:41-62. 2008
  33. pmc Phase I trial of pelvic nodal dose escalation with hypofractionated IMRT for high-risk prostate cancer
    Jarrod B Adkison
    Department of Human Oncology, University of Wisconsin Carbone Cancer Center, School of Medicine and Public Health, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 82:184-90. 2012
    ..In a prospective trial, we tested whether image-guided intensity-modulated radiation therapy (IMRT) can safely deliver escalated nodal doses while treating the prostate with hypofractionated radiotherapy in 5½ weeks...
  34. ncbi request reprint Integral radiation dose to normal structures with conformal external beam radiation
    Hidefumi Aoyama
    Department of Human Oncology, University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 64:962-7. 2006
    ..This study was designed to evaluate the integral dose (ID) received by normal tissue from intensity-modulated radiotherapy (IMRT) for prostate cancer...
  35. pmc On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function
    Stephen R Bowen
    Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, 1530 MSC, 1300 University Ave, Madison, WI 53706, USA
    Phys Med Biol 54:1483-501. 2009
    ..Clinical implementation of dose painting depends on advances in absolute quantification of functional images and improvements in delivery techniques over smaller spatial scales...
  36. ncbi request reprint High-tech in radiation oncology: should there be a ceiling?
    Søren M Bentzen
    Gray Cancer Institute and the Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, United Kingdom
    Int J Radiat Oncol Biol Phys 58:320-30. 2004
    ..To analyze some of the limitations to improvement of the outcome of radiotherapy (RT) expected from the introduction of sophisticated treatment planning and delivery technology...
  37. doi request reprint Balancing on a knife's edge: evidence-based medicine and the marketing of health technology
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 72:12-4; discussion 14-8. 2008
  38. pmc Radiation dose-response model for locally advanced rectal cancer after preoperative chemoradiation therapy
    Ane L Appelt
    Department of Oncology, Vejle Hospital, Vejle, Denmark
    Int J Radiat Oncol Biol Phys 85:74-80. 2013
    ..In the present study we estimated radiation dose-response curves for various grades of tumor regression after preoperative CRT...
  39. ncbi request reprint Evaluation of early and late toxicities in chemoradiation trials
    Søren M Bentzen
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, Madison, WI, USA
    J Clin Oncol 25:4096-103. 2007
    ....
  40. ncbi request reprint Radiation oncology advances: an introduction
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, USA
    Cancer Treat Res 139:1-4. 2008
  41. ncbi request reprint Hypoxia in prostate cancer: correlation of BOLD-MRI with pimonidazole immunohistochemistry-initial observations
    Peter J Hoskin
    Marie Curie Research Wing, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex, UK
    Int J Radiat Oncol Biol Phys 68:1065-71. 2007
    ..To investigate the ability of blood oxygen level-dependent (BOLD) MRI to depict clinically significant prostate tumor hypoxia...
  42. ncbi request reprint Are we influencing outcome in oropharynx cancer with intensity-modulated radiotherapy? An inter-era comparison
    C Wesley Hodge
    Department of Human Oncology, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 69:1032-41. 2007
    ....
  43. ncbi request reprint Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma
    Peter J Hoskin
    Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex, United Kingdom
    J Clin Oncol 28:4912-8. 2010
    ..Phase II clinical studies suggest that hypoxic modification with carbogen and nicotinamide (CON) may increase the efficacy of radiotherapy (RT)...
  44. pmc A new method for synthesizing radiation dose-response data from multiple trials applied to prostate cancer
    Patricia Diez
    Clinical Physics Department, Mount Vernon Centre for Cancer Treatment, Northwood, Middlesex, UK
    Int J Radiat Oncol Biol Phys 77:1066-71. 2010
    ..A new method is presented for synthesizing dose-response data for biochemical control of prostate cancer according to study design (randomized vs. nonrandomized) and risk group (low vs. intermediate-high)...
  45. ncbi request reprint Towards individualized dose constraints: Adjusting the QUANTEC radiation pneumonitis model for clinical risk factors
    Ane L Appelt
    Department of Oncology, Vejle Hospital, Vejle, Denmark
    Acta Oncol 53:605-12. 2014
    ..We propose a method to combine the dose-response relationship for RP in the landmark QUANTEC paper with known clinical risk factors, in order to enable individual risk prediction. The approach is validated in an independent dataset...
  46. doi request reprint Single institution experience treating 104 vestibular schwannomas with fractionated stereotactic radiation therapy or stereotactic radiosurgery
    Bethany M Anderson
    Department of Human Oncology, University of Wisconsin, 600 Highland Avenue, Madison, WI, 53792, USA
    J Neurooncol 116:187-93. 2014
    ..Factors correlating with tumor progression included NF2 and larger tumor size...
  47. doi request reprint Risk of cerebrovascular events in elderly patients after radiation therapy versus surgery for early-stage glottic cancer
    Julian C Hong
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Int J Radiat Oncol Biol Phys 87:290-6. 2013
    ..We assessed whether more limited neck RT used for early-stage (T1-T2 N0) glottic cancer is associated with increased CVD risk, using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database...
  48. pmc Elevation of prostaglandin E2 in lung cancer patients with digital clubbing
    Kevin R Kozak
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    J Thorac Oncol 7:1877-8. 2012
    ..These findings highlight a potential role for PGE2 in the pathogenesis of digital clubbing. Furthermore, this result identifies a lung cancer subpopulation that may uniquely benefit from cyclooxygenase inhibition...
  49. doi request reprint Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
    Gillian C Barnett
    University of Cambridge, Department of Oncology, Cambridge, UK
    Lancet Oncol 13:65-77. 2012
    ..Few associations have been tested in independent validation studies. This prospective study aimed to validate reported associations between genotype and radiation toxicity in a large independent dataset...
  50. pmc Feasibility of dose painting using volumetric modulated arc optimization and delivery
    Stine S Korreman
    University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, Clinical Sciences Center, Madison, Wisconsin, USA
    Acta Oncol 49:964-71. 2010
    ..We investigate dose conformity using the RapidArc optimizer and beam delivery technique. Furthermore, robustness of the plans with respect to positioning uncertainties are evaluated...
  51. ncbi request reprint Recurrences after intensity modulated radiotherapy for head and neck squamous cell carcinoma more likely to originate from regions with high baseline [18F]-FDG uptake
    Anne K Due
    Department of Oncology, Rigshospitalet, University of Copenhagen, Denmark
    Radiother Oncol 111:360-5. 2014
    ..To analyze the recurrence pattern in relation to target volumes and (18)F-fluorodeoxyglucose (FDG) uptake on positron emission tomography in head and neck squamous cell carcinoma (HNSCC) patients treated with definitive chemoradiation...
  52. pmc Intensity-modulated x-ray (IMXT) versus proton (IMPT) therapy for theragnostic hypoxia-based dose painting
    Ryan T Flynn
    Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53703, USA
    Phys Med Biol 53:4153-67. 2008
    ..The distal gradient tracking method resulted in comparable plans to the spot scanning method while reducing the number of proton beam spots by a factor of over 3...
  53. ncbi request reprint Does a local bystander effect necessitate a revision of TCP models that are based on observed clinical data?
    Wolfgang A Tome
    Department of Human Oncology, University of Wisconsin Medical School, Madison, WI 53792, USA
    Acta Oncol 45:406-11. 2006
    ..Based on this new set of assumptions the equation for TCP is derived, first for the homogenous case and then for the general case of a heterogeneous ensemble of tumors irradiated in-homogeneously...
  54. pmc Randomized controlled trials in health technology assessment: overkill or overdue?
    Søren M Bentzen
    Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Radiother Oncol 86:142-7. 2008
    ..Working in a technology and science based medical discipline, radiation oncology researchers need to further develop methodology for critical assessment of health technologies as a complement to randomized controlled trials...
  55. pmc Hippocampal sparing radiotherapy for pediatric medulloblastoma: impact of treatment margins and treatment technique
    N Patrik Brodin
    Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden M B Centre for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden M B Radiation Medicine Research Center, Department of Radiation Oncology, Rigshospitalet, Copenhagen, Denmark N P B, P M R, A K B, C H, I R V, S M B Niels Bohr Institute, University of Copenhagen, Copenhagen, Denmark N P B, P M R Department of Clinical Physiology and Nuclear Medicine, Centre of Diagnostic Investigations, Copenhagen, Denmark A K B Department of Pediatric Oncology, The Queen Silvia Children s Hospital, University of Gothenburg, Gothenburg, Sweden B L Department of Human Oncology, University of Wisconsin Medical School, Madison, Wisconsin S M B Department of Radiation Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden T B E
    Neuro Oncol 16:594-602. 2014
    ....
  56. ncbi request reprint Linear accelerator radiosurgery for trigeminal neuralgia
    Gregory M Richards
    Department of Human Oncology, University of Wisconsin Medical School, K4 B29 Clinical Sciences Center, Madison, Wisconsin 53792, USA
    Neurosurgery 57:1193-200; discussion 1193-200. 2005
    ..To report the clinical outcomes following treatment of trigeminal neuralgia with linear accelerator-based radiosurgery...