Research Topics
| Stephen BentSummaryAffiliation: University of California Country: USA Publications
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Publications
Does this woman have an acute uncomplicated urinary tract infection?Stephen Bent
University of California, San Francisco, San Francisco VAMC, 94121, USA
JAMA 287:2701-10. 2002..Although the clinical encounter typically involves taking a history and performing a physical examination, the diagnostic accuracy of the clinical assessment for UTI remains uncertain...- Brief communication: Better ways to question patients about adverse medical events: a randomized, controlled trialStephen Bent
University of California and San Francisco Veterans Administration Medical Center, San Francisco, California 94121, USA
Ann Intern Med 144:257-61. 2006..There is no standard method of identifying adverse events in clinical trials... - Saw palmetto for benign prostatic hyperplasiaStephen Bent
Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco, San Francisco, USA
N Engl J Med 354:557-66. 2006..Saw palmetto is used by over 2 million men in the United States for the treatment of benign prostatic hyperplasia and is commonly recommended as an alternative to drugs approved by the Food and Drug Administration... 
Spontaneous bleeding associated with ginkgo biloba: a case report and systematic review of the literature: a case report and systematic review of the literatureStephen Bent
Osher Center for Integrative Medicine, University of California, San Francisco, USA
J Gen Intern Med 20:657-61. 2005..Ginkgo biloba (ginkgo) is a herbal remedy used by over 2% of the adult population in the United States. Several review articles have suggested that ginkgo may increase the risk of bleeding...- Safety and efficacy of citrus aurantium for weight lossStephen Bent
Osher Center for Integrative Medicine at the University of California, San Francisco, USA
Am J Cardiol 94:1359-61. 2004.... - Commonly used herbal medicines in the United States: a reviewStephen Bent
Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco, USA
Am J Med 116:478-85. 2004..To improve the safety and consistency of herbs, additional research is needed to define the pharmacology, stability, and bioavailability of these products... - The optimal use of diagnostic testing in women with acute uncomplicated cystitisStephen Bent
Department of Medicine, University of California, San Francisco, USA
Am J Med 113:20S-28S. 2002..Randomized controlled trials are needed to more closely examine the outcomes, costs of care, and patient satisfaction from different diagnostic and management strategies... - The relative safety of ephedra compared with other herbal productsStephen Bent
Osher Center for Integrative Medicine at the University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, 111 A1, 4150 Clement Street, San Francisco, California 94121, USA
Ann Intern Med 138:468-71. 2003..Ephedra is widely used in dietary supplements that are marketed to promote weight loss or increase energy; however, the safety of this product has been questioned because of numerous case reports of adverse events... - A detailed safety assessment of a saw palmetto extractAndrew L Avins
Division of Research, Northern California Kaiser Permanente, San Francisco, CA, USA
Complement Ther Med 16:147-54. 2008..Saw palmetto is commonly used by men for lower-urinary tract symptoms. Despite its widespread use, very little is known about the potential toxicity of this dietary supplement... - Valerian for sleep: a systematic review and meta-analysisStephen Bent
Osher Center for Integrative Medicine, University of California, San Francisco, CA 94121, USA
Am J Med 119:1005-12. 2006..Future studies should assess a range of doses of standardized preparations of valerian and include standard measures of sleep quality and safety... - A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorderStephen Bent
Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco VAMC, 111 A1, 4150 Clement St, San Francisco, CA 94121, USA
J Autism Dev Disord 41:545-54. 2011..Although this pilot study did not find a statistically significant benefit from omega-3 fatty acids, the small sample size does not rule out small to moderate beneficial effects... 
The relation of alpha-linolenic acid to the risk of prostate cancer: a systematic review and meta-analysisJoel A Simon
General Internal Medicine Section, Medical Service, Veterans Affairs Medical Center, San Francisco, CA, USA
Am J Clin Nutr 89:1558S-1564S. 2009..alpha-Linolenic acid (ALA; 18:3n-3) has been associated inconsistently with an increased risk of prostate cancer. Additional studies have become available since the publication of 2 previous meta-analyses...- Omega-3 fatty acids for autistic spectrum disorder: a systematic reviewStephen Bent
Department of Medicine, Osher Center for Integrative Medicine, University of California, San Francisco VAMC, 111 A1 4150 Clement Street, San Francisco, CA 94121, USA
J Autism Dev Disord 39:1145-54. 2009.... - Antibiotic and anti-inflammatory use and the risk of prostate cancerNicholas A Daniels
University of California, San Francisco, Department of Medicine, Division of General Internal Medicine, San Francisco, California, USA
BMC Res Notes 2:57. 2009..05). CONCLUSION: Our analysis did not reveal a relation between use of antibiotics, aspirin, or NSAIDs and the risk of prostate cancer... - Improving the prediction of response to therapy in autismStephen Bent
Department of Psychiatry, University of California, San Francisco, San Francisco, California 94121, USA
Neurotherapeutics 7:232-40. 2010.... - The prognosis and treatment of acquired hemophilia: a systematic review and meta-analysisRhonda L Bitting
University of California San Francisco, USA
Blood Coagul Fibrinolysis 20:517-23. 2009..Although the included studies were not randomized, patients treated with combination chemotherapy had the greatest odds of remission and the lowest odds of death... - The impact of a "low-intensity" versus "high-intensity" medical intensive care unit on patient outcomes in critically ill veteransJonathan P Singer
Division of Pulmonary Critical Care Medicine, UC San Francisco, CA 94143, USA
J Intensive Care Med 25:233-9. 2010.... - Saw palmetto and lower urinary tract symptoms: what is the latest evidence?Andrew L Avins
Northern California Kaiser Permanente Division of Research, 2000 Broadway, 3rd Floor, Oakland, CA 94612, USA
Curr Urol Rep 7:260-5. 2006..Higher-quality studies are currently underway to better define the potential benefits and risks of plant-based extracts for treating symptoms related to benign prostatic hyperplasia... - Procalcitonin-guided antibiotic therapy for chronic obstructive pulmonary disease exacerbationsSofya Tokman
Department of Internal Medicine, University of California, San Francisco, CA, USA
Expert Rev Anti Infect Ther 9:727-35. 2011.... - Use of an embedded N-of-1 trial to improve adherence and increase information from a clinical studyAndrew L Avins
Northern California Kaiser Permanente Division of Research, Oakland, CA 94612, United States
Contemp Clin Trials 26:397-401. 2005..Wider use of formal N-of-1 studies may be a valuable tool for improving adherence and determining whether observed side effects are caused by study medication in clinical trials... - An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomniaBradly P Jacobs
Department of Medicine, Osher Center for Integrative Medicine, University of California San Francisco, California, USA
Medicine (Baltimore) 84:197-207. 2005..Neither kava nor valerian relieved anxiety or insomnia more than placebo. This trial demonstrates the feasibility of conducting randomized, blinded trials entirely via the Internet... - Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical CenterStephen Bent
Osher Center for Integrative Medicine, University of California, San Francisco, CA, USA
J Gen Intern Med 23:854-9. 2008..Although herbs are often perceived as "natural" and therefore safe, many different side effects have been reported owing to active ingredients, contaminants, or interactions with drugs... - Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarinKirsten Neudoerffer Kangelaris
Division of General Internal Medicine, University of California, Box 0131, 533 Parnassus Ave, San Francisco, CA 94143 0131, USA
J Gen Intern Med 24:656-64. 2009..Genotype-guided initial warfarin dosing may reduce over-anticoagulation and serious bleeding compared to a one-dose-fits-all dosing method... - Does this adult patient have septic arthritis?Mary E Margaretten
Division of Rheumatology, PRIME Program, Department of Medicine, University of California, San Francisco, CA 94143 0633, USA
JAMA 297:1478-88. 2007..In patients who present with an acutely painful and swollen joint, prompt identification and treatment of septic arthritis can substantially reduce morbidity and mortality... - Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysisJonathan Z Li
Department of Medicine, San Francisco VA Medical Center, University of California, San Francisco, CA 94143 0862, USA
Am J Med 120:783-90. 2007..The goal of this study is to systematically review randomized controlled trials comparing short-course and extended-course antibiotic regimens for community-acquired pneumonia... - A randomized controlled trial of a Chinese herbal remedy to increase energy, memory, sexual function, and quality of life in elderly adults in Beijing, ChinaStephen Bent
Department of Medicine (SB, SC, University of California, San Francisco, California, USA
Am J Med 115:441-7. 2003..The herbal product was well tolerated. CONCLUSION: Short-term use of a mixture of Chinese herbs was associated with a small benefit in one measure of mental health that is of unclear clinical importance... - Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescentsTeruhiko Terasawa
San Francisco Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California, USA
Ann Intern Med 141:537-46. 2004..Although clinicians commonly use computed tomography or ultrasonography to diagnose acute appendicitis, the accuracy of these imaging tests remains unclear... - Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysisSamir Gupta
University of California, San Francisco, USA
Ann Intern Med 139:46-50. 2003..Even if the "best-case" estimates of AFP sensitivity and specificity are accurate, AFP has limited utility for detecting hepatocellular carcinoma... - N-acetylcysteine for the prevention of contrast-induced nephropathy. A systematic review and meta-analysisRaymond Liu
Department of Medicine, University of California, San Francisco, CA, USA
J Gen Intern Med 20:193-200. 2005..We conducted a systematic review to determine whether administering N-acetylcysteine around the time of contrast administration reduces the risk of contrast-induced nephropathy... - Editorial: assessing the safety of dietary supplementsStephen Bent
Pharmacoepidemiol Drug Saf 16:958-60. 2007 - The optimal use of diagnostic testing in women with acute uncomplicated cystitisStephen Bent
Dis Mon 49:83-98. 2003..Randomized controlled trials are needed to more closely examine the outcomes, costs of care, and patient satisfaction from different diagnostic and management strategies... - Dietary supplement adverse events: report of a one-year poison center surveillance projectChristine Haller
Amgen, Inc Department of Global Regulatory Affairs and Safety, South San Francisco, CA, USA
J Med Toxicol 4:84-92. 2008..Harmful supplements may not be identified for months or years with existing adverse event monitoring mechanisms. Retrospective review of poison center statistics to capture supplement-associated toxicity also has limitations... - Safety review of kava (Piper methysticum) by the Natural Standard Research CollaborationCatherine Ulbricht
Natural Standard Research Collaboration, 1 Broadway, 14th Floor, Cambridge, MA 02142, USA
Expert Opin Drug Saf 4:779-94. 2005.... - Establishing causality from case reports: was ephedra to blame?Stephen Bent
South Med J 99:453-4. 2006