Research Topics
| Abdellatif BenraissSummaryAffiliation: University of Rochester Country: USA Publications
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Detail Information
Publications
Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNFA Benraiss
Department of Neurology, University of Rochester Medical Center, Rochester, NY 14620, USA
Gene Ther 19:483-93. 2012..AAV4:BDNF and noggin-induced neuronal addition may thus provide a means to provide longlasting and persistent striatal neuronal replacement in conditions of striatal neuronal loss, such as HD...
Cellular therapy and induced neuronal replacement for Huntington's diseaseAbdellatif Benraiss
Department of Neurology, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA
Neurotherapeutics 8:577-90. 2011..We will then consider the potential application of gene therapy toward the induction of striatal neurogenesis and neuronal recruitment, with an eye toward its potential therapeutic use in HD...
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington diseaseSung Rae Cho
Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA
J Clin Invest 117:2889-902. 2007..Thus, BDNF and Noggin induced striatal neuronal regeneration, delayed motor impairment, and extended survival in R6/2 mice, suggesting a new therapeutic strategy in Huntington disease...
