Abdellatif Benraiss

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease
    Abdellatif Benraiss
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Cell Stem Cell 12:787-99. 2013
  2. pmc Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF
    A Benraiss
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14620, USA
    Gene Ther 19:483-93. 2012
  3. pmc Cellular therapy and induced neuronal replacement for Huntington's disease
    Abdellatif Benraiss
    Department of Neurology, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA
    Neurotherapeutics 8:577-90. 2011
  4. pmc Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
    Sung Rae Cho
    Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA
    J Clin Invest 117:2889-902. 2007

Collaborators

Detail Information

Publications4

  1. doi request reprint Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease
    Abdellatif Benraiss
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Cell Stem Cell 12:787-99. 2013
    ..In addition, squirrel monkeys given ICV injections of adenoviral BDNF/noggin showed similar addition of striatal neurons. Induced neuronal addition may therefore represent a promising avenue for disease amelioration in HD...
  2. pmc Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF
    A Benraiss
    Department of Neurology, University of Rochester Medical Center, Rochester, NY 14620, USA
    Gene Ther 19:483-93. 2012
    ..AAV4:BDNF and noggin-induced neuronal addition may thus provide a means to provide longlasting and persistent striatal neuronal replacement in conditions of striatal neuronal loss, such as HD...
  3. pmc Cellular therapy and induced neuronal replacement for Huntington's disease
    Abdellatif Benraiss
    Department of Neurology, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA
    Neurotherapeutics 8:577-90. 2011
    ..We will then consider the potential application of gene therapy toward the induction of striatal neurogenesis and neuronal recruitment, with an eye toward its potential therapeutic use in HD...
  4. pmc Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease
    Sung Rae Cho
    Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA
    J Clin Invest 117:2889-902. 2007
    ..Thus, BDNF and Noggin induced striatal neuronal regeneration, delayed motor impairment, and extended survival in R6/2 mice, suggesting a new therapeutic strategy in Huntington disease...