Research Topics
| S BenmansourSummaryAffiliation: University of Texas Health Science Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Comparison of the effects of estradiol and progesterone on serotonergic functionSaloua Benmansour
Department of Pharmacology, University of Texas Health Science Center at San Antonio, 78229 3900, USA
Biol Psychiatry 71:633-41. 2012..In this study, behavioral consequences, as well as receptor mechanisms underlying these hormonal effects, were investigated...
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA levelS Benmansour
Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas 78284, USA
J Neurosci 19:10494-501. 1999..Based on these results, it appears that the SERT is downregulated by chronic administration of SSRIs but not other types of antidepressants; furthermore, the downregulation is not caused by decreases in SERT gene expression...
Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporterSaloua Benmansour
Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
J Neurosci 22:6766-72. 2002..SERT binding sites decreases are not a consequence of reduced SERT gene expression, as revealed by in situ hybridization measurements. SSRI-induced downregulation of the SERT may be a key component for the clinical response to SSRIs...
Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamineSaloua Benmansour
Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
Neuropsychopharmacology 34:555-64. 2009..The finding that acutely both estradiol and progesterone can inhibit the ability of an SSRI to slow the clearance of 5-HT, may have important implications for the use of SSRIs in women...
Regulation of the norepinephrine transporter by chronic administration of antidepressantsSaloua Benmansour
Department of Pharmacology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
Biol Psychiatry 55:313-6. 2004..This study investigated if chronic treatment of rats with selective NRIs or SSRIs also affected the norepinephrine transporter (NET)...
Delayed pharmacological effects of antidepressantsA Frazer
Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Mol Psychiatry 7:S23-8. 2002..Substantial loss of serotonin transporter binding sites takes 15 days to occur and is accompanied by a marked reduction of serotonin transporter function in vivo...
Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodentsSaloua Benmansour
Department of Pharmacology, University of Texas Health Science Center at San Antonio, Texas 78229, USA
Eur J Pharmacol 587:90-8. 2008..Such acute effects of BDNF would be expected to counter early effects of SSRIs, which might, in part, account for some delay in therapeutic effect...
Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampusThierry Deltheil
Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex F 92296, France
Pharmacol Biochem Behav 90:174-83. 2008..Thus, the neurochemical sight of this question will be addressed here by examining the consequences of either a constitutive decrease or increase in brain BDNF protein levels on hippocampal extracellular levels of 5-HT in conscious mice...
