Elizaveta V Benevolenskaya

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation
    Nuria Lopez-Bigas
    Research Unit on Biomedical Informatics, Experimental and Health Science Department, Universitat Pompeu Fabra, Barcelona 08080, Spain
    Mol Cell 31:520-30. 2008
  2. ncbi request reprint Structure of the Drosophila melanogaster annexin X gene
    E V Benevolenskaya
    Institute of Molecular Genetics, Moscow, Russia
    DNA Cell Biol 14:349-57. 1995
  3. ncbi request reprint Histone H3K4 demethylases are essential in development and differentiation
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA
    Biochem Cell Biol 85:435-43. 2007
  4. pmc Loss of dE2F compromises mitochondrial function
    Aaron M Ambrus
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA
    Dev Cell 27:438-51. 2013
  5. pmc Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
    Michael L Beshiri
    Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, IL 60607, USA
    Proc Natl Acad Sci U S A 109:18499-504. 2012
  6. pmc FoxM1 regulates mammary luminal cell fate
    Janai R Carr
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60607, USA
    Cell Rep 1:715-29. 2012
  7. pmc Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina
    Brandon N Nicolay
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Genet 6:e1000918. 2010
  8. pmc Co-regulation of histone-modifying enzymes in cancer
    Abul B M M K Islam
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e24023. 2011
  9. pmc Emerging links between E2F control and mitochondrial function
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois
    Cancer Res 75:619-23. 2015
  10. ncbi request reprint Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
    Elizaveta V Benevolenskaya
    Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell 18:623-35. 2005

Collaborators

  • Jing Li
  • Brandon N Nicolay
  • Larisa Litovchick
  • William Kaelin
  • Grace Guzman
  • Nuria Lopez-Bigas
  • Abul B M M K Islam
  • Aaron M Ambrus
  • Katherine B Holmes
  • Janai R Carr
  • Michael L Beshiri
  • William F Richter
  • Maxim V Frolov
  • Nam Sung Moon
  • Hyun Jung Park
  • Megan M Kiefer
  • Danielle Dewaal
  • Zebin Wang
  • Joel Fontanarosa
  • Nicolas GĂ©vry
  • Qin Yan
  • Dragana Kopanja
  • Lydia Plante
  • SAMUEL HESS
  • Pradip Raychaudhuri
  • Laura A Jacobs
  • Tom L Volkert
  • Tomasz A Kisiel
  • Jennifer Love
  • Heather L Murray
  • Richard A Young
  • Katie B Holmes
  • Sumeet Gupta
  • Dannielle C Dewaal

Detail Information

Publications11

  1. pmc Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation
    Nuria Lopez-Bigas
    Research Unit on Biomedical Informatics, Experimental and Health Science Department, Universitat Pompeu Fabra, Barcelona 08080, Spain
    Mol Cell 31:520-30. 2008
    ..We conclude that, during differentiation, RBP2 exerts inhibitory effects on multiple genes through direct interaction with their promoters...
  2. ncbi request reprint Structure of the Drosophila melanogaster annexin X gene
    E V Benevolenskaya
    Institute of Molecular Genetics, Moscow, Russia
    DNA Cell Biol 14:349-57. 1995
    ..Transcription of the annexin gene was detected in embryonic cell cultures. No profound effects of ecdysterone on the annexin X message content in cell cultures were observed...
  3. ncbi request reprint Histone H3K4 demethylases are essential in development and differentiation
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA
    Biochem Cell Biol 85:435-43. 2007
    ..All 4 proteins possess the demethylase activity specific to H3K4 and belong to the poorly described JARID1 protein family...
  4. pmc Loss of dE2F compromises mitochondrial function
    Aaron M Ambrus
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607, USA
    Dev Cell 27:438-51. 2013
    ..Thus, our results uncover a role of E2F/DP in the regulation of mitochondrial function and demonstrate that this aspect of E2F regulation is critical for the normal induction of apoptosis in response to irradiation. ..
  5. pmc Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
    Michael L Beshiri
    Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, IL 60607, USA
    Proc Natl Acad Sci U S A 109:18499-504. 2012
    ..These findings reveal a critical role of H3K4 demethylation by KDM5A in the transcriptional silencing of genes that are suppressed by RB family members in differentiated cells...
  6. pmc FoxM1 regulates mammary luminal cell fate
    Janai R Carr
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, College of Medicine, Chicago, IL 60607, USA
    Cell Rep 1:715-29. 2012
    ..This study identifies FoxM1 as a critical regulator of mammary differentiation with significant implications for the development of aggressive breast cancers...
  7. pmc Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina
    Brandon N Nicolay
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Genet 6:e1000918. 2010
    ....
  8. pmc Co-regulation of histone-modifying enzymes in cancer
    Abul B M M K Islam
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e24023. 2011
    ..We conclude that changes in coordinated regulation of enzymes executing histone modifications may underlie global epigenetic changes occurring in cancer...
  9. pmc Emerging links between E2F control and mitochondrial function
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois
    Cancer Res 75:619-23. 2015
    ..Thus, this novel function of E2F may have a major impact on cell viability, and it is independent of induction of apoptotic genes. Here, we discuss the implications of these findings in cancer biology...
  10. ncbi request reprint Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
    Elizaveta V Benevolenskaya
    Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell 18:623-35. 2005
    ..Our results suggest that promotion of differentiation by pRB involves neutralization of free RBP2 and transcriptional activation of RBP2 targets linked to euchromatin maintenance...