Elizaveta V Benevolenskaya

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation
    Nuria Lopez-Bigas
    Research Unit on Biomedical Informatics, Experimental and Health Science Department, Universitat Pompeu Fabra, Barcelona 08080, Spain
    Mol Cell 31:520-30. 2008
  2. ncbi Histone H3K4 demethylases are essential in development and differentiation
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA
    Biochem Cell Biol 85:435-43. 2007
  3. ncbi Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
    Michael L Beshiri
    Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, IL 60607, USA
    Proc Natl Acad Sci U S A 109:18499-504. 2012
  4. ncbi Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina
    Brandon N Nicolay
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Genet 6:e1000918. 2010
  5. ncbi Co-regulation of histone-modifying enzymes in cancer
    Abul B M M K Islam
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e24023. 2011
  6. ncbi Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
    Elizaveta V Benevolenskaya
    Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell 18:623-35. 2005

Research Grants

  1. RBP2 regulation through differential recruitment to genomic loci
    Elizaveta V Benevolenskaya; Fiscal Year: 2010

Collaborators

  • William Kaelin
  • Nuria Lopez-Bigas
  • Abul B M M K Islam
  • Michael L Beshiri
  • William F Richter
  • Brandon N Nicolay
  • Katherine B Holmes
  • Larisa Litovchick
  • Qin Yan
  • Nicolas Gévry
  • SAMUEL HESS
  • Lydia Plante
  • Laura A Jacobs
  • Nam Sung Moon
  • Battuya Bayarmagnai
  • Maxim V Frolov
  • Sumeet Gupta
  • Tomasz A Kisiel
  • Dannielle C Dewaal
  • Heather L Murray
  • Tom L Volkert
  • Jennifer Love
  • Richard A Young
  • Katie B Holmes

Detail Information

Publications6

  1. ncbi Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation
    Nuria Lopez-Bigas
    Research Unit on Biomedical Informatics, Experimental and Health Science Department, Universitat Pompeu Fabra, Barcelona 08080, Spain
    Mol Cell 31:520-30. 2008
    ..We conclude that, during differentiation, RBP2 exerts inhibitory effects on multiple genes through direct interaction with their promoters...
  2. ncbi Histone H3K4 demethylases are essential in development and differentiation
    Elizaveta V Benevolenskaya
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 S Ashland Avenue, Chicago, IL 60607, USA
    Biochem Cell Biol 85:435-43. 2007
    ..All 4 proteins possess the demethylase activity specific to H3K4 and belong to the poorly described JARID1 protein family...
  3. ncbi Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
    Michael L Beshiri
    Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, IL 60607, USA
    Proc Natl Acad Sci U S A 109:18499-504. 2012
    ..These findings reveal a critical role of H3K4 demethylation by KDM5A in the transcriptional silencing of genes that are suppressed by RB family members in differentiated cells...
  4. ncbi Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina
    Brandon N Nicolay
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Genet 6:e1000918. 2010
    ....
  5. ncbi Co-regulation of histone-modifying enzymes in cancer
    Abul B M M K Islam
    Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e24023. 2011
    ..We conclude that changes in coordinated regulation of enzymes executing histone modifications may underlie global epigenetic changes occurring in cancer...
  6. ncbi Binding of pRB to the PHD protein RBP2 promotes cellular differentiation
    Elizaveta V Benevolenskaya
    Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell 18:623-35. 2005
    ..Our results suggest that promotion of differentiation by pRB involves neutralization of free RBP2 and transcriptional activation of RBP2 targets linked to euchromatin maintenance...

Research Grants1

  1. RBP2 regulation through differential recruitment to genomic loci
    Elizaveta V Benevolenskaya; Fiscal Year: 2010
    ....