George A Belov

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Rewiring of cellular membrane homeostasis by picornaviruses
    George A Belov
    Department of Veterinary Medicine, Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, USA
    J Virol 88:9478-89. 2014
  2. doi request reprint Modulation of lipid synthesis and trafficking pathways by picornaviruses
    George A Belov
    Department of Veterinary Medicine, University of Maryland, and Virginia Maryland Regional College of Veterinary Medicine, College Park, MD 20742, United States Electronic address
    Curr Opin Virol 9:19-23. 2014
  3. doi request reprint (+)RNA viruses rewire cellular pathways to build replication organelles
    George A Belov
    Virginia Maryland College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USA
    Curr Opin Virol 2:740-7. 2012
  4. pmc Complex dynamic development of poliovirus membranous replication complexes
    George A Belov
    Virginia Maryland College of Veterinary Medicine, University of Maryland, College Park, Maryland 20742, USA
    J Virol 86:302-12. 2012
  5. pmc Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles
    Jules A Nchoutmboube
    Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
    PLoS Pathog 9:e1003401. 2013
  6. pmc A critical role of a cellular membrane traffic protein in poliovirus RNA replication
    George A Belov
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 4:e1000216. 2008
  7. doi request reprint Cell-specific establishment of poliovirus resistance to an inhibitor targeting a cellular protein
    Ekaterina G Viktorova
    Department of Veterinary Medicine, University of Maryland, College Park, Maryland, USA
    J Virol 89:4372-86. 2015
  8. pmc New small-molecule inhibitors effectively blocking picornavirus replication
    Lauren A Ford Siltz
    Department of Veterinary Medicine, University of Maryland, and Virginia Maryland Regional College of Veterinary Medicine, College Park, Maryland, USA
    J Virol 88:11091-107. 2014
  9. doi request reprint Fluorescent fatty acid analogs as a tool to study development of the picornavirus replication organelles
    Ekaterina G Viktorova
    Department of Veterinary Medicine, University of Maryland, College Park, USA
    J Virol Methods 200:15-21. 2014

Collaborators

  • Ellie Ehrenfeld
  • Catherine L Jackson
  • Ekaterina G Viktorova
  • Lauren A Ford-Siltz
  • Jules Nchoutmboube
  • Lauren A Ford Siltz
  • Jules A Nchoutmboube
  • Eugenia Dragunsky
  • Ben Zhang
  • Diana Kouiavskaia
  • Lyle Isaacs
  • Konstantin Chumakov
  • Lauren A Ford
  • Paul A Watkins
  • Alison J Scott
  • Zhengtong Pei
  • Robert K Ernst

Detail Information

Publications9

  1. pmc Rewiring of cellular membrane homeostasis by picornaviruses
    George A Belov
    Department of Veterinary Medicine, Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, USA
    J Virol 88:9478-89. 2014
    ..Despite remarkable progress, our understanding of how a handful of viral proteins can completely overrun the multilayered, complex mechanisms that control the membrane organization of a eukaryotic cell remains very limited. ..
  2. doi request reprint Modulation of lipid synthesis and trafficking pathways by picornaviruses
    George A Belov
    Department of Veterinary Medicine, University of Maryland, and Virginia Maryland Regional College of Veterinary Medicine, College Park, MD 20742, United States Electronic address
    Curr Opin Virol 9:19-23. 2014
    ....
  3. doi request reprint (+)RNA viruses rewire cellular pathways to build replication organelles
    George A Belov
    Virginia Maryland College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USA
    Curr Opin Virol 2:740-7. 2012
    ..Collectively, these studies reveal an unexpected complexity of the spatial organization of the replication membranes and suggest that (+)RNA viruses actively change cellular membrane composition to build their replication organelles...
  4. pmc Complex dynamic development of poliovirus membranous replication complexes
    George A Belov
    Virginia Maryland College of Veterinary Medicine, University of Maryland, College Park, Maryland 20742, USA
    J Virol 86:302-12. 2012
    ..Thus, it is likely that there is a fundamental divergence in the requirements for the supporting cellular membrane-shaping machinery among different groups of positive-strand RNA viruses...
  5. pmc Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles
    Jules A Nchoutmboube
    Virginia Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland, United States of America
    PLoS Pathog 9:e1003401. 2013
    ....
  6. pmc A critical role of a cellular membrane traffic protein in poliovirus RNA replication
    George A Belov
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 4:e1000216. 2008
    ..We identified a mutation in GBF1 that allows growth of poliovirus in the presence of BFA. Interaction between GBF1 and viral protein 3A determined the outcome of infection in the presence of BFA...
  7. doi request reprint Cell-specific establishment of poliovirus resistance to an inhibitor targeting a cellular protein
    Ekaterina G Viktorova
    Department of Veterinary Medicine, University of Maryland, College Park, Maryland, USA
    J Virol 89:4372-86. 2015
    ..Thus, a rational approach to the development of host-targeting antivirals may overcome the superior adaptability of (+)RNA viruses...
  8. pmc New small-molecule inhibitors effectively blocking picornavirus replication
    Lauren A Ford Siltz
    Department of Veterinary Medicine, University of Maryland, and Virginia Maryland Regional College of Veterinary Medicine, College Park, Maryland, USA
    J Virol 88:11091-107. 2014
    ..Multiple attempts to isolate resistant mutants in the presence of A4(1) or E5(1) were unsuccessful, showing that effective broad-spectrum antivirals could be developed on the basis of these compounds...
  9. doi request reprint Fluorescent fatty acid analogs as a tool to study development of the picornavirus replication organelles
    Ekaterina G Viktorova
    Department of Veterinary Medicine, University of Maryland, College Park, USA
    J Virol Methods 200:15-21. 2014
    ....