Affiliation: University of Tennessee
- Chlamydia pneumoniae and atherosclerosisRobert J Belland
University of Tennessee Health Sciences Center, 858 Madison Avenue, Memphis, TN 38163, USA
Cell Microbiol 6:117-27. 2004..Genomic and proteomic analyses of C. pneumoniae infections in relevant cell types will help to define the pathogenic potential of the organism in both respiratory and cardiovascular disease...
- ChlamydiaRobert Belland
University of Tennessee, Memphis, 38163, USA
Nat Rev Microbiol 2:530-1. 2004
- The Chlamydia pneumoniae type III secretion-related lcrH gene clusters are developmentally expressed operonsScot P Ouellette
Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, 38163, USA
J Bacteriol 187:7853-6. 2005....
- Global transcriptional upregulation in the absence of increased translation in Chlamydia during IFNgamma-mediated host cell tryptophan starvationScot P Ouellette
Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Mol Microbiol 62:1387-401. 2006..These observations represent an alternative survival strategy for host-adapted obligate intracellular bacterial pathogens that have lost the genes for stringent control during reductive evolution...
- Isolation of Chlamydia pneumoniae clonal variants by a focus-forming assayJens Gieffers
Laboratory of Intracellular Parasites, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Hamilton, Montana 59840, USA
Infect Immun 70:5827-34. 2002..These results now allow investigations on the biology and pathogenesis of C. pneumoniae clonal genovars that could lead to new insights into the pathogenesis of this important human pathogen...
- Micromanipulation of the Chlamydia pneumoniae inclusion: implications for cloning and host-pathogen interactionsJens Gieffers
Laboratory of Intracellular Parasites, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT 59840, USA
FEMS Microbiol Lett 226:45-9. 2003..We have used micromanipulation to clone C. pneumoniae and to free it from mycoplasma contamination...
- Genotypic differences in the Chlamydia pneumoniae tyrP locus related to vascular tropism and pathogenicityJens Gieffers
Laboratory of Intracellular Parasites, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA
J Infect Dis 188:1085-93. 2003..We hypothesize that the important difference between strains of vascular and respiratory origin may lie in the increased tendency of vascular strains to elicit persistent infection that is triggered by amino-acid starvation...
- Transcriptome analysis of chlamydial growth during IFN-gamma-mediated persistence and reactivationRobert J Belland
Laboratories of Intracellular Parasites and Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA
Proc Natl Acad Sci U S A 100:15971-6. 2003..In contrast to the paradigm of persistence as a general stress response, our findings suggest that persistence is an alternative life cycle used by chlamydiae to avoid the host immune response...
- The chlamydial developmental cycleYasser M Abdelrahman
Department of Molecular Sciences, University of Tennessee Health Sciences Center, 858 Madison Avenue, Memphis, TN 38163, USA
FEMS Microbiol Rev 29:949-59. 2005..Measuring transcriptional changes throughout the cycle has allowed investigators to determine the nature of the temporal gene expression changes required for bacterial growth and development...
- Transcriptional Control of Chlamydial DevelopmentRobert Belland; Fiscal Year: 2009..These regulators control important aspects of the bacteria's response to its environment and their role in normal and chronic forms of infection will be studied. ..