Research TopicsGenomes and Genes
| Kiflai BeinSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
JUN-CCAAT/enhancer-binding protein complexes inhibit surfactant-associated protein B promoter activityKiflai Bein
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, PA 15219 3130, USA
Am J Respir Cell Mol Biol 45:436-44. 2011..These findings support the idea that heterodimerization between JUN and C/EBP-α and/or C/EBP-β targets JUN to the Sftpb promoter, thereby mediating its inhibitory regulatory role...
Functional genomics of chlorine-induced acute lung injury in miceGeorge D Leikauf
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219 3130, USA
Proc Am Thorac Soc 7:294-6. 2010..Gene-targeted mice then could be used to test the functional significance of susceptibility candidate genes, which could be valuable in revealing novel insights into the biology of acute lung injury...
Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1George D Leikauf
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
Am J Respir Crit Care Med 183:1499-509. 2011..Because acute lung injury is a sporadic disease produced by heterogeneous precipitating factors, previous genetic analyses are mainly limited to candidate gene case-control studies...
Integrative metabolome and transcriptome profiling reveals discordant energetic stress between mouse strains with differential sensitivity to acrolein-induced acute lung injuryJames P Fabisiak
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
Mol Nutr Food Res 55:1423-34. 2011..A respiratory irritant, acrolein is generated by overheating cooking oils or by domestic cooking using biomass fuels, and is in environmental tobacco smoke, a health hazard in the restaurant workplace...
Acrolein - a pulmonary hazardKiflai Bein
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219 3130, USA
Mol Nutr Food Res 55:1342-60. 2011..Consequent to its pathophysiological impact, acrolein contributes to the morbidly and mortality associated with acute lung injury and COPD, and possibly asthma and lung cancer...
