Martin J Behne

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores
    Martin J Behne
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 121:688-94. 2003
  2. ncbi NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging
    Martin J Behne
    Dermatology Service, Veterans Affairs Medical Center and Department of Dermatology, University of California, San Francisco, California 94121, USA
    J Biol Chem 277:47399-406. 2002
  3. ncbi Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function
    Martin J Behne
    Department of Dermatology, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Invest Dermatol 120:998-1006. 2003
  4. ncbi Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum
    Joachim W Fluhr
    Dermatology and Medical Service, Veterans Affairs Medical Center, and Department of Dermatology, University of California, San Francisco, 94121, USA
    J Invest Dermatol 122:320-9. 2004
  5. ncbi Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes
    Ida Aronchik
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 121:681-7. 2003
  6. ncbi Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation
    Karin M Aberg
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 127:1973-9. 2007
  7. pmc Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development
    James A McCormick
    Departments of Medicine and Molecular and Cellular Pharmacology, University of California, San Francisco, CA 94143, USA
    Mol Biol Cell 15:4278-88. 2004
  8. ncbi Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress
    Yoshikazu Uchida
    Dermatology Service, Department of Veterans Affairs Medical Center, San Francisco, CA, USA
    J Lipid Res 43:1293-302. 2002
  9. pmc Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient
    Kerry M Hanson
    Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois, Urbana Champaign, Illinois 61801, USA
    Biophys J 83:1682-90. 2002
  10. ncbi Defective cyclic guanosine monophosphate-gated calcium channels and the pathogenesis of psoriasis
    Roddie C McKenzie
    Epidermal Inflammation and Protection Group, Department of Dermatology, University of Edinburgh, Edinburgh, Scotland, UK
    Acta Derm Venereol 83:414-8. 2003

Collaborators

Detail Information

Publications11

  1. ncbi Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores
    Martin J Behne
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 121:688-94. 2003
    ..In this report we localize the ATP2C1, demonstrate its physiologic relevance in mammalian cells, and measure intraorganelle Golgi Ca2+ in keratinocytes...
  2. ncbi NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging
    Martin J Behne
    Dermatology Service, Veterans Affairs Medical Center and Department of Dermatology, University of California, San Francisco, California 94121, USA
    J Biol Chem 277:47399-406. 2002
    ....
  3. ncbi Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function
    Martin J Behne
    Department of Dermatology, University of California San Francisco, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Invest Dermatol 120:998-1006. 2003
    ..Thus, full barrier competence appears to require the extension of acidification in microdomains from the SC/SG interface outward toward the skin surface in the immediate postnatal period...
  4. ncbi Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum
    Joachim W Fluhr
    Dermatology and Medical Service, Veterans Affairs Medical Center, and Department of Dermatology, University of California, San Francisco, 94121, USA
    J Invest Dermatol 122:320-9. 2004
    ..Conversely, the impaired acidification of neonatal SC, which has important functional and clinical consequences, can be explained by the relatively low activities of one or both of these mechanisms at birth...
  5. ncbi Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes
    Ida Aronchik
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 121:681-7. 2003
    ..In addition, these findings implicate inadequate ATP stores as an additional cause in the pathogenesis of HHD and suggest novel therapeutic options...
  6. ncbi Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation
    Karin M Aberg
    Department of Dermatology, University of California, San Francisco, California, USA
    J Invest Dermatol 127:1973-9. 2007
    ..This report provides new insights into differentiation defects in HHD and its relationship to Ca2+ signaling...
  7. pmc Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development
    James A McCormick
    Departments of Medicine and Molecular and Cellular Pharmacology, University of California, San Francisco, CA 94143, USA
    Mol Biol Cell 15:4278-88. 2004
    ..These data establish a role for SGK3 in normal postnatal hair follicle development, possibly involving effects on beta-catenin/Lef-1-mediated gene transcription...
  8. ncbi Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress
    Yoshikazu Uchida
    Dermatology Service, Department of Veterans Affairs Medical Center, San Francisco, CA, USA
    J Lipid Res 43:1293-302. 2002
    ..Thus, SMase-induced stress initiates a response in keratinocytes that includes upregulation of GlcCer synthesis which may protect against the deleterious effects of excess Cer...
  9. pmc Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient
    Kerry M Hanson
    Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois, Urbana Champaign, Illinois 61801, USA
    Biophys J 83:1682-90. 2002
    ..The data definitively show that the stratum corneum acid mantle results from the presence of aqueous acidic pockets within the lipid-rich extracellular matrix...
  10. ncbi Defective cyclic guanosine monophosphate-gated calcium channels and the pathogenesis of psoriasis
    Roddie C McKenzie
    Epidermal Inflammation and Protection Group, Department of Dermatology, University of Edinburgh, Edinburgh, Scotland, UK
    Acta Derm Venereol 83:414-8. 2003
    ....
  11. ncbi Regulation of epidermal tight-junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains
    Ulrich Ohnemus
    Department of Dermatology and Venerology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    J Invest Dermatol 128:906-16. 2008
    ..aureus. As we did not find a change in actin, and as changes of TJ preceded alterations of AJs and desmosomes, we suggest that S. aureus targets TJ...