Antoine Bechara

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective
    Antoine Bechara
    Institute for the Neurological Study of Emotion and Creativity, Department of Psychology, University of Southern California, Los Angeles, California 90089 2520, USA
    Nat Neurosci 8:1458-63. 2005
  2. pmc Is there a recovery of decision-making function after frontal lobe damage? A study using alternative versions of the Iowa Gambling Task
    Lin Xiao
    Brain and Creativity Institute and Department of Psychology, University of Southern California, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 35:518-29. 2013
  3. doi request reprint Processing of time within the prefrontal cortex: recent time engages posterior areas whereas distant time engages anterior areas
    Gilly Koritzky
    Brain and Creativity Institute, University of Southern California, CA 90089 2520, USA
    Neuroimage 72:280-6. 2013
  4. doi request reprint Failure to learn from repeated mistakes: persistent decision-making impairment as measured by the iowa gambling task in patients with ventromedial prefrontal cortex lesions
    Samantha M Waters-Wood
    Department of Psychology, University of Southern California, Los Angeles, California 90089 2520, USA
    J Int Neuropsychol Soc 18:927-30. 2012
  5. pmc An fMRI study of risk-taking following wins and losses: implications for the gambler's fallacy
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, California 90089 1061, USA
    Hum Brain Mapp 32:271-81. 2011
  6. doi request reprint Abnormal affective decision making revealed in adolescent binge drinkers using a functional magnetic resonance imaging study
    Lin Xiao
    Department of Psychology, Dana and David Dornsife Cognitive Neuroscience Imaging Center, University of Southern California, Los Angeles, CA 90089 2520, USA
    Psychol Addict Behav 27:443-54. 2013
  7. pmc The impact of prior risk experiences on subsequent risky decision-making: the role of the insula
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, CA 90089 1061, USA
    Neuroimage 50:709-16. 2010
  8. pmc COMT Val158Met polymorphism interacts with stressful life events and parental warmth to influence decision making
    Qinghua He
    Brain and Creativity Institute, University of Southern California, Los Angeles, California 90089, USA
    Sci Rep 2:677. 2012
  9. pmc Affective decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in 10th grade Chinese adolescent binge drinkers
    C Anderson Johnson
    Institute for Health Promotion and Disease Prevention Research, University of Southern California, Los Angeles, CA 91803, United States
    Neuropsychologia 46:714-26. 2008
  10. pmc Affective decision-making predictive of Chinese adolescent drinking behaviors
    Lin Xiao
    Department of Psychology, Brain and Creativity Institute, University of Southern California, Los Angeles, California, USA
    J Int Neuropsychol Soc 15:547-57. 2009

Research Grants

  1. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2009
  2. Residual Effects of Ecstasy on Decision-Making & Driving
    Antoine Bechara; Fiscal Year: 2007
  3. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2004
  4. COGNITIVE AND NEURAL MECHANISMS OF SUBSTANCE ABUSE
    Antoine Bechara; Fiscal Year: 2004
  5. PHARMACOLOGICAL BASIS OF DECISION-MAKING
    Antoine Bechara; Fiscal Year: 2002
  6. COGNITIVE AND NEURAL MECHANISMS OF SUBSTANCE ABUSE
    Antoine Bechara; Fiscal Year: 2000
  7. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2010

Detail Information

Publications60

  1. ncbi request reprint Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective
    Antoine Bechara
    Institute for the Neurological Study of Emotion and Creativity, Department of Psychology, University of Southern California, Los Angeles, California 90089 2520, USA
    Nat Neurosci 8:1458-63. 2005
    ....
  2. pmc Is there a recovery of decision-making function after frontal lobe damage? A study using alternative versions of the Iowa Gambling Task
    Lin Xiao
    Brain and Creativity Institute and Department of Psychology, University of Southern California, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 35:518-29. 2013
    ..Additionally, these results are consistent with findings from the original studies using the IGT with patients with damage to the vmPFC, which showed that decision-making impairments do not recover over time...
  3. doi request reprint Processing of time within the prefrontal cortex: recent time engages posterior areas whereas distant time engages anterior areas
    Gilly Koritzky
    Brain and Creativity Institute, University of Southern California, CA 90089 2520, USA
    Neuroimage 72:280-6. 2013
    ..Results indicate that individual differences in the effect of recent outcomes correspond to differences in the locus of activation, with elevated recency associated with more posterior loci of activation...
  4. doi request reprint Failure to learn from repeated mistakes: persistent decision-making impairment as measured by the iowa gambling task in patients with ventromedial prefrontal cortex lesions
    Samantha M Waters-Wood
    Department of Psychology, University of Southern California, Los Angeles, California 90089 2520, USA
    J Int Neuropsychol Soc 18:927-30. 2012
    ..These results validate the clinical observations that VMPFC dysfunction does not appear to be subject to autonomous recovery over time in real-life. (JINS, 2012, 18, 1-4)...
  5. pmc An fMRI study of risk-taking following wins and losses: implications for the gambler's fallacy
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, California 90089 1061, USA
    Hum Brain Mapp 32:271-81. 2011
    ..This has significant implications for our understanding of the gambler's fallacy and human decision making under risk...
  6. doi request reprint Abnormal affective decision making revealed in adolescent binge drinkers using a functional magnetic resonance imaging study
    Lin Xiao
    Department of Psychology, Dana and David Dornsife Cognitive Neuroscience Imaging Center, University of Southern California, Los Angeles, CA 90089 2520, USA
    Psychol Addict Behav 27:443-54. 2013
    ..These findings have social implications because they potentially reveal underlying neural mechanisms for making poor decisions, which may increase an individual's risk and vulnerability for alcoholism...
  7. pmc The impact of prior risk experiences on subsequent risky decision-making: the role of the insula
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, CA 90089 1061, USA
    Neuroimage 50:709-16. 2010
    ..These findings suggest that the insula plays an important role in activating representations of homeostatic states associated with the experience of risk, which in turn exerts an influence on subsequent decisions...
  8. pmc COMT Val158Met polymorphism interacts with stressful life events and parental warmth to influence decision making
    Qinghua He
    Brain and Creativity Institute, University of Southern California, Los Angeles, California 90089, USA
    Sci Rep 2:677. 2012
    ..These results shed some new light on gene-environment interactions in decision making, which could potentially help us understand the underlying etiology of several psychiatric disorders associated with decision making impairment...
  9. pmc Affective decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in 10th grade Chinese adolescent binge drinkers
    C Anderson Johnson
    Institute for Health Promotion and Disease Prevention Research, University of Southern California, Los Angeles, CA 91803, United States
    Neuropsychologia 46:714-26. 2008
    ....
  10. pmc Affective decision-making predictive of Chinese adolescent drinking behaviors
    Lin Xiao
    Department of Psychology, Brain and Creativity Institute, University of Southern California, Los Angeles, California, USA
    J Int Neuropsychol Soc 15:547-57. 2009
    ..These findings suggest that deficits in affective decision making may be important independent determinants of compulsive drinking and potentially addictive behavior in adolescents...
  11. pmc Affective decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in 10th-grade Chinese adolescent smokers
    Lin Xiao
    Brain and Creativity Institute, University of Southern California, Los Angeles, CA 91803, USA
    Nicotine Tob Res 10:1085-97. 2008
    ..Intervention targeting affective decision making might hold promise for reducing adolescents' risks for substance use...
  12. doi request reprint Decision making in children and adolescents: impaired Iowa Gambling Task performance in early adolescence
    Dana G Smith
    Department of Psychology, Brain and Creativity Institute, University of Southern California, USA
    Dev Psychol 48:1180-7. 2012
    ..This trajectory is in stark contrast with the linear development of memory, speed of processing, and other cognitive abilities over the ages...
  13. pmc A neuropsychological approach to understanding risk-taking for potential gains and losses
    Irwin P Levin
    Department of Psychology, University of Iowa Iowa City, IA, USA
    Front Neurosci 6:15. 2012
    ..Taken together, these studies support a clear functional dissociation between risk-taking for gains and risk-taking for losses, and further dissociation at the neural level...
  14. pmc The Iowa Gambling Task in fMRI images
    Xiangrui Li
    Department of Psychology, Dana and David Dornsife Cognitive Neuroscience Imaging Center, University of Southern California, Los Angeles, 90089 2520, USA
    Hum Brain Mapp 31:410-23. 2010
    ..These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations...
  15. pmc The gambler's fallacy is associated with weak affective decision making but strong cognitive ability
    Gui Xue
    National Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    PLoS ONE 7:e47019. 2012
    ..Our result provides a novel insight into the mechanisms underlying the GF, which highlights the significant role of affective mechanisms in adaptive decision-making...
  16. pmc Smoking cessation after brain damage does not lead to increased depression: implications for understanding the psychiatric complications of varenicline
    Daniel Tranel
    Department of Neurology, Division of Behavioral Neurology and Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Cogn Behav Neurol 25:16-24. 2012
    ..However, the cause of depression and related symptoms in persons who quit smoking after taking varenicline remains uncertain, because smoking cessation itself can cause such symptoms...
  17. pmc A somatic marker perspective of immoral and corrupt behavior
    Mona Sobhani
    Brain and Creativity Institute, University of Southern California, Los Angeles, CA 90089 2520, USA
    Soc Neurosci 6:640-52. 2011
    ....
  18. pmc Amygdala contribution to selective dimensions of emotion
    Gary G Berntson
    Department of Psychology, Ohio State University, Columbus, Ohio 43210, USA
    Soc Cogn Affect Neurosci 2:123-9. 2007
    ..The relative lack of emotional arousal to negative stimuli may account for many of the clinical features of amygdala lesions...
  19. pmc Functional dissociations of risk and reward processing in the medial prefrontal cortex
    Gui Xue
    Department of Psychology, University of Southern California, Los Angeles, CA 90089 1061, USA
    Cereb Cortex 19:1019-27. 2009
    ..e., aversion to uncertainty vs. approach to rewarding outcomes), where the relative strengths of these signals determine behavioral decisions involving risk and uncertainty...
  20. ncbi request reprint Patients with Huntington's disease have impaired awareness of cognitive, emotional, and functional abilities
    Karin F Hoth
    Department of Psychology, University of Iowa, Iowa City, IA, USA
    J Clin Exp Neuropsychol 29:365-76. 2007
    ..Future studies will benefit also from examining the association between awareness and cognition in larger samples...
  21. ncbi request reprint Decision making and free will: a neuroscience perspective
    Kelly Burns
    Brain and Creativity Institute and Department of Psychology, University of Southern California, Los Angeles, CA 90089, USA
    Behav Sci Law 25:263-80. 2007
    ..Using the criminal law as an example, we discuss how new discoveries in neuroscience can serve as a tool for reprioritizing our society's legal intuitions in a way that leads us to a more effective and humane system...
  22. ncbi request reprint Neurocognitive deficits related to poor decision making in people behind bars
    Eldad Yechiam
    Technion Israel Institute of Technology, Haifa, Israel
    Psychon Bull Rev 15:44-51. 2008
    ..The present cognitive model provides a novel way for building a bridge between cognitive neuroscience and complex human behaviors...
  23. ncbi request reprint Response inhibition deficit is involved in poor decision making under risk in nonamnesic individuals with alcoholism
    Xavier Noel
    Clinic of Addictions, Brugmann Hospital, Free University of Brussels, Brussels, Belgium
    Neuropsychology 21:778-86. 2007
    ..These results underline the important role that response inhibition plays in decision making, especially in risky situations, when knowledge of the probability of a given outcome becomes available (i.e. decisions under risk)...
  24. ncbi request reprint Neural correlates of adaptive decision making for risky gains and losses
    Joshua A Weller
    Decision Research, Eugene, Oregon 97401, USA
    Psychol Sci 18:958-64. 2007
    ..This research further demonstrates the role of emotion in decision competence...
  25. pmc Are all drug addicts impulsive? Effects of antisociality and extent of multidrug use on cognitive and motor impulsivity
    Jasmin Vassileva
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60622, USA
    Addict Behav 32:3071-6. 2007
    ..Results suggest that a subclinical form of antisociality may have a paradoxically facilitating effect on decision-making and cognitive impulsivity among SDIs...
  26. ncbi request reprint Exploring the neurological substrate of emotional and social intelligence
    Reuven Bar-On
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Brain 126:1790-800. 2003
    ....
  27. ncbi request reprint Alcohol cues increase cognitive impulsivity in individuals with alcoholism
    Xavier Noel
    Clinic of Addictions, C H U Brugmann, Free University of Brussels ULB, Salle 72, 4, Place Van Gehuchten, 1020, Brussels, Belgium
    Psychopharmacology (Berl) 192:291-8. 2007
    ..We tested the hypothesis that alcoholics exhibit greater cognitive disinhibition when the response to be suppressed is associated with alcohol-related information...
  28. ncbi request reprint Time course of attention for alcohol cues in abstinent alcoholic patients: the role of initial orienting
    Xavier Noel
    Clinic of Addictions, Brugmann Hospital, Universite Libre de Bruxelles, 4 Place Van Gehuchten, 1020 Brussels, Belgium
    Alcohol Clin Exp Res 30:1871-7. 2006
    ..Here, we examine 2 distinct components of attention in abstinent alcohol-dependent individuals and social drinkers of alcohol, that is to say, the initial orienting to alcohol-related cues, and the maintenance of attention to them...
  29. ncbi request reprint Decision-making and addiction (part I): impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences
    Antoine Bechara
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Neuropsychologia 40:1675-89. 2002
    ..Thus, the dysfunctional VM cortex underlying the "myopia" for the future in some SDI may be one of the principle mechanisms underlying the transition from casual substance taking to compulsive and uncontrollable behavior...
  30. ncbi request reprint Cognitive impulsivity and HIV serostatus in substance dependent males
    Eileen M Martin
    Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Int Neuropsychol Soc 10:931-8. 2004
    ..Implications of these findings for future basic and applied studies of HIV and substance dependence are discussed...
  31. ncbi request reprint Investment behavior and the negative side of emotion
    Baba Shiv
    Stanford University, CA 94305 5015, USA
    Psychol Sci 16:435-9. 2005
    ....
  32. ncbi request reprint The role of emotion in decision-making: evidence from neurological patients with orbitofrontal damage
    Antoine Bechara
    Department of Neurology, University of Iowa, Iowa City, IA 52242, USA
    Brain Cogn 55:30-40. 2004
    ..The implications of this theoretical framework for the normal and abnormal development of the orbitofrontal cortex are also discussed...
  33. ncbi request reprint Cognitive biases toward alcohol-related words and executive deficits in polysubstance abusers with alcoholism
    Xavier Noel
    Clinic of Addictions, Brugmann Hospital, Free University of Brussels, Belgium
    Addiction 100:1302-9. 2005
    ..To study cognitive biases for alcohol-related cues on executive function tasks involving mental flexibility and response inhibition in polysubstance abusers with alcoholism...
  34. ncbi request reprint Impaired decision making related to working memory deficits in individuals with substance addictions
    Antoine Bechara
    Department of Neurology, University of Iowa, Iowa City, IA, USA
    Neuropsychology 18:152-62. 2004
    ..M. Martin et al., 2003). The authors suggest that the prefrontal cortex hosts multiple distinct mechanisms of decision making and inhibitory control and that ISDs may be affected in any one or combination of them...
  35. ncbi request reprint Impulsivity and decision making
    Ariane Zermatten
    Cognitive Psychopathology and Neuropsychology Unit, University of Geneva, Geneva, Switzerland
    J Nerv Ment Dis 193:647-50. 2005
    ..This suggests that premeditation is related to decision making influenced by somatic (or emotional) markers...
  36. ncbi request reprint Decision-making and impulse control after frontal lobe injuries
    Antoine Bechara
    Division of Cognitive Neuroscience, Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Curr Opin Neurol 18:734-9. 2005
    ..The present review highlights recent progress made in this area of research...
  37. ncbi request reprint Using cognitive models to map relations between neuropsychological disorders and human decision-making deficits
    Eldad Yechiam
    Indiana University, IN, USA
    Psychol Sci 16:973-8. 2005
    ..These findings demonstrate the potential contribution of cognitive models in building bridges between neuroscience and behavior...
  38. ncbi request reprint Delayed nonmatch-to-sample performance in HIV-seropositive and HIV-seronegative polydrug abusers
    Eileen M Martin
    Department of Psychiatry, University of Illinois at Chicago and Chicago Veterans Health Care System West Side Division, 60612, USA
    Neuropsychology 17:283-8. 2003
    ..HIV-associated WM defects are not critically dependent on the amount of time stimulus representations must be maintained and might be attributed to impaired encoding or retrieval of stimulus representations...
  39. ncbi request reprint The dark side of emotion in decision-making: when individuals with decreased emotional reactions make more advantageous decisions
    Baba Shiv
    Tippie College of Business, University of Iowa, Iowa City, IA 52242, USA
    Brain Res Cogn Brain Res 23:85-92. 2005
    ....
  40. ncbi request reprint Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward?
    Antoine Bechara
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Neuropsychologia 40:1690-705. 2002
    ..A third sub-population is hypersensitive to reward, so that the presence or the prospect of receiving, reward dominates their behavior...
  41. ncbi request reprint Executive dysfunction in substance dependent individuals during drug use and abstinence: an examination of the behavioral, cognitive and emotional correlates of addiction
    Antonio Verdejo-Garcia
    Department of Neurology, University of Iowa, Iowa City, USA
    J Int Neuropsychol Soc 12:405-15. 2006
    ..Cognitive, behavioral, and emotional measures were moderately correlated...
  42. ncbi request reprint Impairments of emotion and real-world complex behavior following childhood- or adult-onset damage to ventromedial prefrontal cortex
    Steven W Anderson
    Department of Neurology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Int Neuropsychol Soc 12:224-35. 2006
    ..Greater focus on the contribution of emotional dysfunction to the real-world competencies of patients with damage in the VM region may sharpen their neuropsychological assessment and facilitate rehabilitation efforts...
  43. ncbi request reprint Executive functions among individuals with methamphetamine or alcohol as drugs of choice: preliminary observations
    Raul Gonzalez
    Department of Psychiatry, University of Illinois Chicago, Chicago, IL 60622, USA
    J Clin Exp Neuropsychol 29:155-9. 2007
    ..These preliminary findings suggest that self-reported drug of choice on admission to treatment may be associated with different patterns of executive performance during early recovery...
  44. ncbi request reprint Asymmetric functional roles of right and left ventromedial prefrontal cortices in social conduct, decision-making, and emotional processing
    Daniel Tranel
    Department of Neurology, Division of Cognitive Neuroscience, University of Iowa College of Medicine, Iowa City 52242, USA
    Cortex 38:589-612. 2002
    ....
  45. ncbi request reprint Risky business: emotion, decision-making, and addiction
    Antoine Bechara
    Department of Neurology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Gambl Stud 19:23-51. 2003
    ..Using neurocognitive criteria could lead to more accurate subtyping of addictive disorders, and perhaps serve as a guide for more specific, and potentially more successful, behavioral and pharmacological interventions...
  46. ncbi request reprint Psychophysiological anticipation of positive outcomes promotes advantageous decision-making in normal older persons
    Natalie L Denburg
    Department of Neurology, Division of Cognitive Neuroscience, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa 52242 1053, USA
    Int J Psychophysiol 61:19-25. 2006
    ....
  47. ncbi request reprint The neurology of social cognition
    Antoine Bechara
    Brain 125:1673-5. 2002
  48. ncbi request reprint The effects of vagus nerve stimulation on decision-making
    Coleman O Martin
    Department of Neurology, University of Iowa College of Medicine, Iowa City 52242, USA
    Cortex 40:605-12. 2004
    ..Although these results should be viewed as preliminary, they suggest that the vagus nerve is a conduit for afferent somatic signals that can influence decision-making...
  49. ncbi request reprint Role of the amygdala in decision-making
    Antoine Bechara
    Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
    Ann N Y Acad Sci 985:356-69. 2003
    ....
  50. pmc Electrophysiological correlates of reward prediction error recorded in the human prefrontal cortex
    Hiroyuki Oya
    Department of Neurosurgery and Neurology, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 102:8351-6. 2005
    ..The finding implicates this brain region in the acquisition of choice bias by means of a continuous updating of expectations about reward and punishment...
  51. pmc Emotion-based decision-making in healthy subjects: short-term effects of reducing dopamine levels
    Serge Sevy
    Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Yeshiva University, Bronx, and Psychiatry Research Department, The Zucker Hillside Hospital, Glen Oaks, NY, USA
    Psychopharmacology (Berl) 188:228-35. 2006
    ..So far, it is unclear what aspects of addictive behaviors are related to a dopaminergic dysfunction...
  52. pmc Iowa gambling task in schizophrenia: a review and new data in patients with schizophrenia and co-occurring cannabis use disorders
    Serge Sevy
    Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY, 11004, USA
    Schizophr Res 92:74-84. 2007
    ..To test this hypothesis, we compared schizophrenia patients with (SCZ((+))) or without (SCZ((-))) cannabis use disorders, to healthy subjects, on measures of cognition and IGT performance...
  53. pmc Skin conductance responses are elicited by the airway sensory effects of puffs from cigarettes
    Nasir H Naqvi
    Division of Cognitive Neuroscience, Department of Neurology, University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
    Int J Psychophysiol 61:77-86. 2006
    ..The implications of these findings for the classical conditioning model, as well as for other learning models, are discussed...
  54. ncbi request reprint Characteristics of prospective memory deficits in HIV-seropositive substance-dependent individuals: preliminary observations
    Eileen M Martin
    Department of Psychiatry, University of Illinois, Chicago, IL 60612, USA
    J Clin Exp Neuropsychol 29:496-504. 2007
    ..These preliminary data provide new and unique findings regarding the components of executive function mediated by prefrontal cortical systems that are impaired among HIV+ SDIs and their relevance to "real-world" behaviors...
  55. ncbi request reprint Negative emotion-driven impulsivity predicts substance dependence problems
    Antonio Verdejo-Garcia
    Pharmacology and Clinical Neurosciences Research Unit, Institut Municipal d Investigacio Medica, Parc de Recerca Biomedica de Barcelona, Dr Aiguader 88, Barcelona 08003, Spain
    Drug Alcohol Depend 91:213-9. 2007
    ..Thus, our results could have important implications for novel treatment approaches for substance dependence focused on emotional regulation...
  56. pmc The orbitofrontal cortex, real-world decision making, and normal aging
    Natalie L Denburg
    Department of Neurology, Division of Cognitive Neuroscience, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242 1053, USA
    Ann N Y Acad Sci 1121:480-98. 2007
    ..Finally, we present data demonstrating that poor decision makers are more likely to fall prey to deceptive advertising, suggesting compromise of real-world judgment and decision-making abilities...
  57. pmc Neural correlates of envisioning emotional events in the near and far future
    Arnaud D'Argembeau
    Department of Cognitive Sciences, University of Liege, Boulevard du rectorat 3 B33, Liege, Belgium
    Neuroimage 40:398-407. 2008
    ..On the other hand, the caudate might support more concrete simulations of action plans to achieve rewarding situations in the near future...
  58. ncbi request reprint Does gender play a role in functional asymmetry of ventromedial prefrontal cortex?
    Daniel Tranel
    Department of Neurology, Division of Cognitive Neuroscience, University of Iowa College of Medicine, IA, USA
    Brain 128:2872-81. 2005
    ..men may use a more holistic, gestalt-type strategy, and women may use a more analytic, verbally-mediated strategy. Such differences could reflect asymmetric, gender-related differences in the neurobiology of left and right VMPC sectors...
  59. ncbi request reprint The influence of executive functions, sensation seeking, and HIV serostatus on the risky sexual practices of substance-dependent individuals
    Raul Gonzalez
    University of Illinois Chicago, Department of Psychiatry, M C 912, 1601 W Taylor Street, Room 408, Chicago, IL 60612, USA
    J Int Neuropsychol Soc 11:121-31. 2005
    ..Our findings indicate that continued risk behavior among HIV+ drug users may be driven by sensation seeking (a personality trait common among drug users); however, the impact of executive functions is less clear...
  60. ncbi request reprint Decisions under ambiguity and decisions under risk: correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules
    Matthias Brand
    Department of Physiological Psychology, University of Bielefeld, Bielefeld, Germany
    J Clin Exp Neuropsychol 29:86-99. 2007
    ..Results have impact on the interpretation of deficient IGT performance in patients with frontal lobe dysfunctions...

Research Grants17

  1. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2009
    ....
  2. Residual Effects of Ecstasy on Decision-Making & Driving
    Antoine Bechara; Fiscal Year: 2007
    ..On the social front, the study helps shed more light on how to identify individuals who may present a risk to others and to themselves on the road. ..
  3. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2004
    ..Thus, the proposed research is a beginning of a novel approach with potential for developing more effective therapies for breaking the vicious cycle of addiction. ..
  4. COGNITIVE AND NEURAL MECHANISMS OF SUBSTANCE ABUSE
    Antoine Bechara; Fiscal Year: 2004
    ..abstract_text> ..
  5. PHARMACOLOGICAL BASIS OF DECISION-MAKING
    Antoine Bechara; Fiscal Year: 2002
    ..abstract_text> ..
  6. COGNITIVE AND NEURAL MECHANISMS OF SUBSTANCE ABUSE
    Antoine Bechara; Fiscal Year: 2000
    ..Thus, this research is a beginning that may guide the future development of pharmacotherapeutic strategies that help improve the methods of treatment and prevention of substance abuse. ..
  7. Changes in Addictive Behaviors after Brain Lesions
    Antoine Bechara; Fiscal Year: 2010
    ....