Allison L Bayer

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells
    Allison L Bayer
    Department of Microbiology and Immunology, Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Immunol 181:225-34. 2008
  2. ncbi request reprint Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 1600 Northwest 10th Avenue, Miami, FL 33136, USA
    J Immunol 178:4062-71. 2007
  3. doi request reprint IL-2 family of cytokines in T regulatory cell development and homeostasis
    Thomas R Malek
    Department of Microbiology and Immunology, University of Miami, RMSB 3119, Miami, FL, USA
    J Clin Immunol 28:635-9. 2008
  4. pmc Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Exp Med 201:769-77. 2005
  5. ncbi request reprint Cutting edge: allogeneic CD4+CD25+Foxp3+ T regulatory cells suppress autoimmunity while establishing transplantation tolerance
    Dennis Adeegbe
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
    J Immunol 176:7149-53. 2006
  6. ncbi request reprint Quantitative assessment concerning the contribution of IL-2Rbeta for superantigen-mediated T cell responses in vivo
    Haoli Jin
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, PO Box 016960, Miami, FL 33101, USA
    Int Immunol 18:565-72. 2006
  7. pmc Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCT
    Allison L Bayer
    Department of Microbiology Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
    Blood 113:733-43. 2009
  8. pmc Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy
    Gaetano Faleo
    Diabetes Research Institute, Cell Transplant Center, University ofMiami, Miami, Florida, USA
    Diabetes 61:1769-78. 2012
  9. doi request reprint The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, 33101, USA
    Immunol Res 57:197-209. 2013
  10. ncbi request reprint Tolerance, not immunity, crucially depends on IL-2
    Thomas R Malek
    Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida 33136, USA
    Nat Rev Immunol 4:665-74. 2004

Collaborators

Detail Information

Publications10

  1. pmc A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells
    Allison L Bayer
    Department of Microbiology and Immunology, Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Immunol 181:225-34. 2008
    ..Collectively, these data indicate that IL-7R signaling contributes to Treg cell development and peripheral homeostasis...
  2. ncbi request reprint Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 1600 Northwest 10th Avenue, Miami, FL 33136, USA
    J Immunol 178:4062-71. 2007
    ..Collectively, these data support the notion that normally IL-2 is a dominant mechanism controlling the number of thymic and peripheral T(reg) cells...
  3. doi request reprint IL-2 family of cytokines in T regulatory cell development and homeostasis
    Thomas R Malek
    Department of Microbiology and Immunology, University of Miami, RMSB 3119, Miami, FL, USA
    J Clin Immunol 28:635-9. 2008
    ..Interleukin 2 (IL-2) induces an essential signal for T regulatory (Treg) cells. Without a functional IL-2R, only immature CD4(+) Foxp3(low) CD25(neg) T cells develop, and these cells fail to suppress autoreactive T cells in the periphery...
  4. pmc Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    J Exp Med 201:769-77. 2005
    ..However, for normal neonates, blockade of IL-2 decreased T(reg) cells in both the thymus and LN. Therefore, two steps of T(reg) cell development depend upon IL-2 in neonatal mice, thymus production, and subsequent expansion in the LN...
  5. ncbi request reprint Cutting edge: allogeneic CD4+CD25+Foxp3+ T regulatory cells suppress autoimmunity while establishing transplantation tolerance
    Dennis Adeegbe
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
    J Immunol 176:7149-53. 2006
    ..Collectively, these data demonstrate that effective engraftment by allogeneic Treg cells controls autoimmunity and results in permissive conditions for long-term acceptance of allografts...
  6. ncbi request reprint Quantitative assessment concerning the contribution of IL-2Rbeta for superantigen-mediated T cell responses in vivo
    Haoli Jin
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, PO Box 016960, Miami, FL 33101, USA
    Int Immunol 18:565-72. 2006
    ....
  7. pmc Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCT
    Allison L Bayer
    Department of Microbiology Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
    Blood 113:733-43. 2009
    ....
  8. pmc Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy
    Gaetano Faleo
    Diabetes Research Institute, Cell Transplant Center, University ofMiami, Miami, Florida, USA
    Diabetes 61:1769-78. 2012
    ..The safety profile and noninvasiveness makes HOT an appealing adjuvant therapy for diabetes prevention and intervention trials...
  9. doi request reprint The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation
    Allison L Bayer
    Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, 33101, USA
    Immunol Res 57:197-209. 2013
    ..In parallel, we are pursuing studies in preclinical models of autoimmunity and transplantation to define critical factors for successful adoptive Treg therapy and develop clinically applicable therapeutic protocols...
  10. ncbi request reprint Tolerance, not immunity, crucially depends on IL-2
    Thomas R Malek
    Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida 33136, USA
    Nat Rev Immunol 4:665-74. 2004
    ..Here, we discuss these findings and, in particular, the action of IL-2 on regulatory T cells and effector cells, and the targeting of IL-2 and/or the IL-2 receptor in clinical settings...