Research Topics
Genomes and GenesSpecies | Allison L BayerSummaryAffiliation: University of Miami Country: USA Publications
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Publications
A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cellsAllison L Bayer
Department of Microbiology and Immunology, Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
J Immunol 181:225-34. 2008..Collectively, these data indicate that IL-7R signaling contributes to Treg cell development and peripheral homeostasis...
Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cellsAllison L Bayer
Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, 1600 Northwest 10th Avenue, Miami, FL 33136, USA
J Immunol 178:4062-71. 2007..Collectively, these data support the notion that normally IL-2 is a dominant mechanism controlling the number of thymic and peripheral T(reg) cells...
IL-2 family of cytokines in T regulatory cell development and homeostasisThomas R Malek
Department of Microbiology and Immunology, University of Miami, RMSB 3119, Miami, FL, USA
J Clin Immunol 28:635-9. 2008..Interleukin 2 (IL-2) induces an essential signal for T regulatory (Treg) cells. Without a functional IL-2R, only immature CD4(+) Foxp3(low) CD25(neg) T cells develop, and these cells fail to suppress autoreactive T cells in the periphery...
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal periodAllison L Bayer
Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
J Exp Med 201:769-77. 2005..However, for normal neonates, blockade of IL-2 decreased T(reg) cells in both the thymus and LN. Therefore, two steps of T(reg) cell development depend upon IL-2 in neonatal mice, thymus production, and subsequent expansion in the LN...
Cutting edge: allogeneic CD4+CD25+Foxp3+ T regulatory cells suppress autoimmunity while establishing transplantation toleranceDennis Adeegbe
Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
J Immunol 176:7149-53. 2006..Collectively, these data demonstrate that effective engraftment by allogeneic Treg cells controls autoimmunity and results in permissive conditions for long-term acceptance of allografts...
Quantitative assessment concerning the contribution of IL-2Rbeta for superantigen-mediated T cell responses in vivoHaoli Jin
Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, PO Box 016960, Miami, FL 33101, USA
Int Immunol 18:565-72. 2006....
Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCTAllison L Bayer
Department of Microbiology Immunology, Miller School of Medicine, University of Miami, FL 33101, USA
Blood 113:733-43. 2009....
Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapyGaetano Faleo
Diabetes Research Institute, Cell Transplant Center, University ofMiami, Miami, Florida, USA
Diabetes 61:1769-78. 2012..The safety profile and noninvasiveness makes HOT an appealing adjuvant therapy for diabetes prevention and intervention trials...
Tolerance, not immunity, crucially depends on IL-2Thomas R Malek
Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida 33136, USA
Nat Rev Immunol 4:665-74. 2004..Here, we discuss these findings and, in particular, the action of IL-2 on regulatory T cells and effector cells, and the targeting of IL-2 and/or the IL-2 receptor in clinical settings...
