Research Topics
Species | Lance BauerSummaryAffiliation: University of Connecticut Health Center Country: USA Publications
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Publications
Frontal P300 decrements, childhood conduct disorder, family history, and the prediction of relapse among abstinent cocaine abusersL O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030 2103, USA
Drug Alcohol Depend 44:1-10. 1997..e., relapse versus continued abstinence. Discriminant function analysis revealed that P300 amplitude alone accurately identified 70.6% of the patients who later relapsed, and 53.3% of the patients who did not...
Sensorimotor dysfunction in HIV/AIDS: effects of antiretroviral treatment and comorbid psychiatric disordersLance O Bauer
Departments of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
AIDS 19:495-502. 2005..Objective evidence of these problems has rarely been reported, however. Furthermore, the extent to which balance and gait are influenced by antiretroviral medications or comorbid psychiatric disorders has rarely been examined...- ASPD blunts the effects of HIV and antiretroviral treatment on event-related brain potentialsLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
Neuropsychobiology 53:17-25. 2006..The diminished response to treatment is more likely related to a pre-existing neurophysiological decrement localized to the same brain regions where HIV/AIDS and antiretroviral treatment exert their maximal effect... - Interactive effects of hypertension and alcohol dependence on the P300 event-related potential in African-AmericansLance O Bauer
Neural Dynamics Laboratory, University of Connecticut School of Medicine, Farmington, Connecticut, USA
Clin EEG Neurosci 37:210-4. 2006..Future studies should continue to examine the potential synergistic effects of alcohol dependence and hypertension with a view toward identifying and reducing neurophysiological decrements and stroke risk among middle-aged patients... - The effects of HIV on P300 are moderated by familial risk for substance dependence: implications for a theory of brain reserveLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, United States
Drug Alcohol Depend 94:92-100. 2008..In addition, it tested the convergent validity of 2 operational definitions of premorbid reserve: verbal IQ (VIQ) and a family history (FH) of substance abuse or dependence... - A family history of psychopathology modifies the decrement in cognitive control among patients with HIV/AIDSLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA
Brain Cogn 67:103-14. 2008..The effects of familial risk on this slow potential are sufficiently robust as to attenuate the effects of HIV/AIDS on the probable generators of the response: the anterior cingulate and prefrontal cortex... - Psychiatric and neurophysiological predictors of obesity in HIV/AIDSLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut 0603 2103, USA
Psychophysiology 45:1055-63. 2008..This relationship was mediated through premature response preparation (anterior scalp CNV amplitude) and its hypothesized association with impatience/impulsivity... - P300 and the stroop effect in overweight minority adolescentsLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
Neuropsychobiology 61:180-7. 2010..The goal was to examine the relationship between a risk factor for poor cognitive control and a health outcome of growing public significance--an excess body mass--among adolescents... - Interactive effects of HIV/AIDS, body mass, and substance abuse on the frontal brain: a P300 studyLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
Psychiatry Res 185:232-7. 2011..Substance abuse, likewise, interacts with HIV/AIDS but may impair frontal brain function via a different mechanism... - Brain maturation and subtypes of conduct disorder: interactive effects on p300 amplitude and topography in male adolescentsLance O Bauer
Department of Psychiatry, University of Connecticutt Health Center, University of Connecticutt School of Medicine, Farmington 06030, USA
J Am Acad Child Adolesc Psychiatry 42:106-15. 2003..This study was designed to identify the neurophysiological correlates of different categories of conduct disorder problems as well as the relationship between these correlates and the maturational status of the brain... - Lateral asymmetries in the frontal brain: effects of depression and a family history of alcoholism in female adolescentsLance O Bauer
Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030 2103, USA
Alcohol Clin Exp Res 26:1662-8. 2002..The present study attempted to discern whether these abnormalities reflect a main effect or an interaction between depression and either of two family history variables--a family history of alcoholism or a family history of depression... - Obesity, smoking, and frontal brain dysfunctionLance Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut 06030 2103, USA
Am J Addict 19:391-400. 2010..Smoking may affect brain function by a different mechanism to reduce posterior scalp P300a and P300b amplitudes while preserving frontal scalp P300a latency and amplitude... - Differential effects of alcohol, cocaine, and opioid abuse on event-related potentials recorded during a response competition taskLance O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, MC2103, Farmington, CT 06030 2103, USA
Drug Alcohol Depend 66:137-45. 2002..The present results have implications for the assessment of specific cognitive problems which could foster drug abuse... - Effects of alcoholism, anxiety and depression on P300 in women: a pilot studyL O Bauer
Alcohol Research Center, University of Connecticut Health Center, Farmington 06030, USA
J Stud Alcohol 62:571-9. 2001..The present investigation was designed for the purpose of revealing functional brain impairments associated with alcoholism, anxiety and depression... - Predicting relapse to alcohol and drug abuse via quantitative electroencephalographyL O Bauer
Department of Psychiatry, MC 2103, University of Connecticut Health Center, Farmington, CT 06030, USA
Neuropsychopharmacology 25:332-40. 2001..The enhancement of fast beta electroencephalographic activity in patients who will later relapse most likely originates from a premorbid and subtle dysfunction involving frontal brain regions... - CNS recovery from cocaine, cocaine and alcohol, or opioid dependence: a P300 studyL O Bauer
Department of Psychiatry MC2103, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
Clin Neurophysiol 112:1508-15. 2001..In addition, the effects of selected premorbid and comorbid factors were examined... - Antisocial personality disorder and cocaine dependence: their effects on behavioral and electroencephalographic measures of time estimationL O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
Drug Alcohol Depend 63:87-95. 2001..The potential relevance of these findings for studies of future time orientation and delay discounting behavior are discussed... - Effects of chronic opioid dependence and HIV-1 infection on pattern shift visual evoked potentialsL O Bauer
Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030 2103, USA
Drug Alcohol Depend 50:147-55. 1998..These results are interpreted as reflecting an adverse effect of chronic opioid dependence on neural transmission within primary visual areas of the brain... - Genetic influences on bipolar EEG power spectraYongqiang Tang
Neurodynamics Laboratory, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, USA
Int J Psychophysiol 65:2-9. 2007..Other heritability patterns were also identified within each frequency band. Our results suggest that substantial proportions of the variability in the bipolar EEG measures are explained by genetic factors... - Effects of borderline personality disorder features and a family history of alcohol or drug dependence on P300 in adolescentsRebecca J Houston
Alcohol Research Center, Department of Psychiatry, MC 2103, University of Connecticut Health Center, Farmington, CT 06030 2103, USA
Int J Psychophysiol 53:57-70. 2004.... - P300 evidence of cognitive inflexibility in female adolescents at risk for recurrent depressionRebecca J Houston
Alcohol Research Center, Department of Psychiatry, University of Connecticut Health Center, MC 2103, School of Medicine, Farmington, CT 06030 2103, USA
Prog Neuropsychopharmacol Biol Psychiatry 28:529-36. 2004..These results suggest that depression history as well as task difficulty/modality may influence the utility of the P300 in documenting the neurophysiological aspects of depression... - Delta and theta oscillations as risk markers in adolescent offspring of alcoholicsMadhavi Rangaswamy
Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, NY 11203, USA
Int J Psychophysiol 63:3-15. 2007.... - Depression and familial risk for substance dependence: a P300 study of young womenRebecca J Houston
Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, MC 2103, Farmington, CT 06030 2103, USA
Psychiatry Res 124:49-62. 2003..These results provide further support for the notion that the cognitive difficulties associated with depression are subtle and best detected with sensitive neurophysiological indices, such as P300... - Searching for the full picture: structural equation modeling in alcohol researchMarc A Schuckit
Department of Psychiatry, University of California at San Diego and VA San Diego Healthcare System, San Diego, California 92161 2002, USA
Alcohol Clin Exp Res 30:194-202. 2006..This is followed by a description of the application of SEM to an affect-related model as discussed by John Kramer and Kathleen Bucholz. Finally, Kenneth Sher offers thoughts on how to place these findings into perspective... - Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball taskAjayan Padmanabhapillai
Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, SUNY, HSCB, Brooklyn, NY 11203, USA
Int J Psychophysiol 62:262-71. 2006..The results indicate that the deficient early evoked gamma band response may precede the development of alcoholism and could be a potential endophenotypic marker of alcoholism risk... - Linkage and linkage disequilibrium mapping of ERP and EEG phenotypesBernice Porjesz
Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, Box 1203, HSCB, 450 Clarkson Avenue, Brooklyn, NY 11203 2098, USA
Biol Psychol 61:229-48. 2002..The advent of genomics and proteomics and a fuller understanding of gene regulation, will open new horizons on the critical electrical events so essential for human brain function... - Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognitionKevin A Jones
Department of Psychiatry, Neurodynamics Laboratory, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USA
Int J Psychophysiol 53:75-90. 2004..001). These findings were not observed for the equivalent non-target case data, suggesting a role for the CHRM2 gene in higher cognitive processing in humans... - Resting EEG in offspring of male alcoholics: beta frequenciesMadhavi Rangaswamy
Department of Psychiatry, State University of New York, Health Science Center at Brooklyn (SUNY/HSCB, Box 1203, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
Int J Psychophysiol 51:239-51. 2004..The results indicate that increased EEG beta power can be considered as a likely marker of risk for developing alcoholism and may be used as a predictive endophenotype... - Effects of antisocial personality, cocaine and opioid dependence, and gender on eye movement controlNatalie A Ceballos
Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, 06030-2103, USA
Psychol Rep 95:551-63. 2004..The results suggest that the neurophysiological effects of cocaine dependence and antisocial personality overshadow the effects of heroin. The significance of these findings for visual attention and reading skill has yet to be assessed... - A cholinergic receptor gene (CHRM2) affects event-related oscillationsKevin A Jones
Department of Psychiatry, SUNY Health Science Center, 450 Clarkson Avenue, Box 1203, Brooklyn, NY 11203, USA
Behav Genet 36:627-39. 2006..These findings underscore the utility of electrophysiology and neurogenetics in the understanding of cognitive function and the study of brain-related disorders... - Beta power in the EEG of alcoholicsMadhavi Rangaswamy
Department of Psychiatry, State University of New York, SUNY Health Sciences Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY, USA
Biol Psychiatry 52:831-42. 2002..This feature is more prominent in male alcoholics. The increased beta power in the resting EEG may be an electrophysiological index of the imbalance in the excitation-inhibition homeostasis in the cortex... - Variation in GABRA2 predicts drinking behavior in project MATCH subjectsLance O Bauer
Department of Psychiatry, Alcohol Research Center, University of Connecticut School of Medicine, Farmington, Connecticut 06030 2103, USA
Alcohol Clin Exp Res 31:1780-7. 2007..The present study examines the association of a GABRA2 SNP with another definition of alcohol involvement and with the effects of psychosocial treatment... - Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locusBernice Porjesz
Department of Psychiatry, State University of New York, Health Science Center, Brooklyn, NY 11203, USA
Proc Natl Acad Sci U S A 99:3729-33. 2002..Uncovering the genes influencing brain oscillations provides a better understanding of the neural function involved in information processing... - N400 as an index of semantic expectancies: differential effects of alcohol and cocaine dependenceNatalie A Ceballos
Department of Behavioral Sciences, 1035 University Drive, 236 Medical School Building, University of Minnesota School of Medicine, Duluth, MN 55812 3031, United States
Prog Neuropsychopharmacol Biol Psychiatry 29:936-43. 2005..The contributions of age, gender, and comorbid marijuana and nicotine dependence, and antisocial symptomology to N400 decrements were either covaried or controlled... - Borderline personality disorder features in adolescent girls: P300 evidence of altered brain maturationRebecca J Houston
Research Institute on Addictions State University of New York at Buffalo, 1021 Main Street, Buffalo, NY 14203, USA
Clin Neurophysiol 116:1424-32. 2005..To examine brain maturation in adolescent girls with borderline personality disorder (BPD) features using the P300 event-related potential... - Patterns of regional brain activity in alcohol-dependent subjectsElizabeth P Hayden
University of Western Ontario, London, Ontario, Canada
Alcohol Clin Exp Res 30:1986-91. 2006..It is also unclear whether psychiatric comorbidity in AD subjects accounts for additional variance in frontal asymmetry, beyond a diagnosis of AD alone... - Brain maturation in conduct disorder versus borderline personality disorderNatalie A Ceballos
Department of Behavioral Sciences, University of Minnesota Medical School Duluth, Duluth, Minn 55812, USA
Neuropsychobiology 53:94-100. 2006..The different brain maturation patterns seen in adolescents with CD versus BPD symptoms may contribute to differences in age-of-onset, clinical course, and resistance to treatment... - Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillationsHoward J Edenberg
Indiana University School of Medicine, Indianapolis 46202, USA
Am J Hum Genet 74:705-14. 2004....
Research Grants
- POST-DOCTORAL TRAINING PROGRAM IN ALCOHOL STUDIESLance Bauer; Fiscal Year: 2007..At other times, they will receive individualized training in a specialized area under the supervision of an assigned mentor. ..
- NEUROIMAGING OF HIV AND COMORBID DISORDERSLance Bauer; Fiscal Year: 2003..An analysis of change scores across groups will permit a formal test of the effects of antiviral treatment on neurophysiological status. ..
- Genetic Versus Phenotypic Markers of Relapse RiskLance Bauer; Fiscal Year: 2009....