Alison K Bauer

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure
    Ross S Osgood
    Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Center, Aurora, Colorado, United States of America
    PLoS ONE 8:e65150. 2013
  2. pmc The involvement of NRF2 in lung cancer
    Alison K Bauer
    Department of Environmental and Occupational Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Oxid Med Cell Longev 2013:746432. 2013
  3. pmc Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e26590. 2011
  4. pmc Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Environ Health Perspect 119:1091-7. 2011
  5. ncbi request reprint Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines
    Lori D Dwyer-Nield
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 26:1196-206. 2005
  6. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
  7. ncbi request reprint Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado Health Sciences Center, Denver 80262, USA
    Cancer Res 62:6850-6. 2002
  8. pmc Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
    Elizabeth A Rondini
    Department of Pathobiology and Diagnostic Investigation and Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 48824, USA
    Part Fibre Toxicol 7:9. 2010
  9. doi request reprint Genetic mechanisms of susceptibility to ozone-induced lung disease
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Ann N Y Acad Sci 1203:113-9. 2010
  10. ncbi request reprint Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, Denver CO 80262, USA
    Carcinogenesis 23:1653-60. 2002

Collaborators

Detail Information

Publications11

  1. pmc Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure
    Ross S Osgood
    Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Center, Aurora, Colorado, United States of America
    PLoS ONE 8:e65150. 2013
    ....
  2. pmc The involvement of NRF2 in lung cancer
    Alison K Bauer
    Department of Environmental and Occupational Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Oxid Med Cell Longev 2013:746432. 2013
    ..In this paper, we will discuss the studies on human NRF2 and the mechanisms proposed, several mouse models using various mice deficient in NRF2, as well as xenograft models, and the chemotherapeutic strategies using the NRF2 pathway...
  3. pmc Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
    PLoS ONE 6:e26590. 2011
    ..Our results were consistent with the concept that Nrf2 over-activation is an adaptive response of cancer conferring resistance to anti-cancer drugs and promoting malignancy...
  4. pmc Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Environ Health Perspect 119:1091-7. 2011
    ..Toll-like receptor 4 (TLR4) is involved in ozone (O3)-induced pulmonary hyperpermeability and inflammation, although the downstream signaling events are unknown...
  5. ncbi request reprint Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines
    Lori D Dwyer-Nield
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 26:1196-206. 2005
    ....
  6. pmc Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, USA
    Mol Cancer 8:107. 2009
    ..This study was designed to identify TLR4-mediated gene expression pathways that may be used as prognostic indicators of susceptibility to lung tumorigenesis in mice and provide insight into the mechanism...
  7. ncbi request reprint Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado Health Sciences Center, Denver 80262, USA
    Cancer Res 62:6850-6. 2002
    ..The substantial (80%) reduction in lung tumor multiplicity in iNOS (-/-) mice strongly supports examining iNOS-specific inhibitors as potential lung cancer chemopreventive agents...
  8. pmc Vanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner
    Elizabeth A Rondini
    Department of Pathobiology and Diagnostic Investigation and Center for Integrative Toxicology, Michigan State University, East Lansing, MI, 48824, USA
    Part Fibre Toxicol 7:9. 2010
    ....
  9. doi request reprint Genetic mechanisms of susceptibility to ozone-induced lung disease
    Alison K Bauer
    Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, USA
    Ann N Y Acad Sci 1203:113-9. 2010
    ..Combined investigations across cell models, inbred mice, and humans have provided, and will continue to provide, important insight to understanding genetic factors that contribute to differential susceptibility to oxidants...
  10. ncbi request reprint Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice
    Lori R Kisley
    Department of Pharmaceutical Sciences, University of Colorado Cancer Center, Denver CO 80262, USA
    Carcinogenesis 23:1653-60. 2002
    ..As the production of eicosanoids in addition to PGE2 is also inhibited by celecoxib, and as celecoxib has COX-independent interactions, its effects on tumor formation may vary in different organ systems...
  11. ncbi request reprint Quantitative trait locus mapping of susceptibilities to butylated hydroxytoluene-induced lung tumor promotion and pulmonary inflammation in CXB mice
    Alvin M Malkinson
    Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Carcinogenesis 23:411-7. 2002
    ..The fact that common chromosomal locations regulate both inflammation and carcinogenesis suggests a pathogenic role of inflammatory mediators in tumor development that may be exploited for chemoprevention of lung cancer...