Richard C Bates

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells
    Richard C Bates
    Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Mass 01605 2324, USA
    Cells Tissues Organs 185:29-39. 2007
  2. ncbi The alphaVbeta6 integrin as a novel molecular target for colorectal cancer
    Richard C Bates
    University of Massachusetts Medical School, Department of Cancer Biology, Worcester, MA 01605 2324 USA
    Future Oncol 1:821-8. 2005
  3. ncbi Colorectal cancer progression: integrin alphavbeta6 and the epithelial-mesenchymal transition (EMT)
    Richard C Bates
    Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachsetts 01605, USA
    Cell Cycle 4:1350-2. 2005
  4. ncbi The epithelial-mesenchymal transition (EMT) and colorectal cancer progression
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachussetts, USA
    Cancer Biol Ther 4:365-70. 2005
  5. ncbi Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    J Clin Invest 115:339-47. 2005
  6. ncbi The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston MA 02215, USA
    Exp Cell Res 299:315-24. 2004
  7. ncbi Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease
    David I Bellovin
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 65:10938-45. 2005
  8. ncbi Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Curr Biol 13:1721-7. 2003
  9. ncbi Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Mol Biol Cell 14:1790-800. 2003
  10. ncbi Autocrine signaling in carcinoma: VEGF and the alpha6beta4 integrin
    Arthur M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Semin Cancer Biol 14:115-22. 2004

Collaborators

Detail Information

Publications10

  1. ncbi Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells
    Richard C Bates
    Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Mass 01605 2324, USA
    Cells Tissues Organs 185:29-39. 2007
    ....
  2. ncbi The alphaVbeta6 integrin as a novel molecular target for colorectal cancer
    Richard C Bates
    University of Massachusetts Medical School, Department of Cancer Biology, Worcester, MA 01605 2324 USA
    Future Oncol 1:821-8. 2005
    ..Taken together with its normal expression pattern and known biologic functions, alphaVbeta6 thus emerges as a novel therapeutic candidate...
  3. ncbi Colorectal cancer progression: integrin alphavbeta6 and the epithelial-mesenchymal transition (EMT)
    Richard C Bates
    Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachsetts 01605, USA
    Cell Cycle 4:1350-2. 2005
    ..These findings reinforce the importance of the EMT event in late stage tumorigenesis, and define alphavbeta6 as a novel therapeutic candidate for aggressive colorectal cancer...
  4. ncbi The epithelial-mesenchymal transition (EMT) and colorectal cancer progression
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachussetts, USA
    Cancer Biol Ther 4:365-70. 2005
    ..Thus, the EMT appears to be an integral component of colorectal cancer progression and its analysis can yield novel targets for prognosis and therapy...
  5. ncbi Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    J Clin Invest 115:339-47. 2005
    ..These findings define the alphavbeta6 integrin as an important risk factor for early-stage disease and a novel therapeutic candidate for colorectal cancer...
  6. ncbi The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston MA 02215, USA
    Exp Cell Res 299:315-24. 2004
    ..These studies establish that the regulated expression of a specific chemokine and its receptor are linked to the EMT and they provide a biochemical framework for understanding the mechanisms by which the EMT promotes migration...
  7. ncbi Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease
    David I Bellovin
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 65:10938-45. 2005
    ..These data provide a compelling argument for the importance of both p120ctn and the EMT itself in the progression of colorectal carcinoma...
  8. ncbi Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Curr Biol 13:1721-7. 2003
    ..A role for Flt-1 in cell survival is unprecedented and has significant implications for Flt-1 function in tumor progression, as well as in other biological processes, including angiogenesis and development...
  9. ncbi Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
    Richard C Bates
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Mol Biol Cell 14:1790-800. 2003
    ..These results establish a novel role for the stroma in influencing EMT in colon carcinoma, and they identify a selective advantage to the stromal presence of infiltrating leukocytes in regulating malignant tumor progression...
  10. ncbi Autocrine signaling in carcinoma: VEGF and the alpha6beta4 integrin
    Arthur M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Semin Cancer Biol 14:115-22. 2004
    ....