Devraj Basu

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy
    Devraj Basu
    The Wistar Institute and Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 7:151-2. 2008
  2. pmc Evidence for mesenchymal-like sub-populations within squamous cell carcinomas possessing chemoresistance and phenotypic plasticity
    D Basu
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Oncogene 29:4170-82. 2010
  3. pmc Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas
    Devraj Basu
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    Cell Cycle 10:2008-16. 2011
  4. pmc EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas
    Devraj Basu
    Corresponding Authors Meenhard Herlyn, The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104
    Mol Cancer Ther 12:2176-86. 2013
  5. pmc Stem-like cells and therapy resistance in squamous cell carcinomas
    Nicole Facompre
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA The Wistar Institute, Philadelphia, PA, USA
    Adv Pharmacol 65:235-65. 2012
  6. pmc A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors
    Shinya Ohashi
    Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Cancer Res 71:6836-47. 2011
  7. pmc A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
    Alexander Roesch
    The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
    Cell 141:583-94. 2010

Collaborators

Detail Information

Publications7

  1. ncbi Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy
    Devraj Basu
    The Wistar Institute and Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 7:151-2. 2008
  2. pmc Evidence for mesenchymal-like sub-populations within squamous cell carcinomas possessing chemoresistance and phenotypic plasticity
    D Basu
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Oncogene 29:4170-82. 2010
    ..Taken together, these results provide evidence for a low-turnover, mesenchymal-like sub-population in SCCs with diminished EGFR pathway function and intrinsic resistance to conventional and EGFR-targeted chemotherapies...
  3. pmc Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas
    Devraj Basu
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    Cell Cycle 10:2008-16. 2011
    ..Further, they provide evidence of mesenchymal-like subsets being well-represented across advanced stage SCCs, suggesting that intrinsic drug resistance in this subpopulation has high clinical relevance...
  4. pmc EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas
    Devraj Basu
    Corresponding Authors Meenhard Herlyn, The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104
    Mol Cancer Ther 12:2176-86. 2013
    ..They further show that EGFR inhibition can promote an infiltrative invasion front composed of mesenchymal-like cells preferentially in tumors where they are abundant before therapy...
  5. pmc Stem-like cells and therapy resistance in squamous cell carcinomas
    Nicole Facompre
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA The Wistar Institute, Philadelphia, PA, USA
    Adv Pharmacol 65:235-65. 2012
    ..Development of novel SCC therapies will be aided by pursuing such mechanisms as well as refining current definitions for CSCs and clarifying their relevance to hierarchical versus dynamic models of stemness...
  6. pmc A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors
    Shinya Ohashi
    Gastroenterology Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Cancer Res 71:6836-47. 2011
    ....
  7. pmc A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
    Alexander Roesch
    The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
    Cell 141:583-94. 2010
    ..These results suggest a new understanding of melanoma heterogeneity with tumor maintenance as a dynamic process mediated by a temporarily distinct subpopulation...