Boris C Bastian

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia
    Boris C Bastian
    Departments of Dermatology and Pathology, Cardiovascular Research Institute, University of California, San Francisco, California 94158 9001 email
    Annu Rev Pathol 9:239-71. 2014
  2. ncbi Distinct sets of genetic alterations in melanoma
    John A Curtin
    Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143 0808, USA
    N Engl J Med 353:2135-47. 2005
  3. ncbi Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases
    Jeffrey P North
    Departments of Pathology Dermatology The Helen Diller Comprehensive Cancer Center, University of California, San Francisco, CA
    Am J Surg Pathol 38:824-31. 2014
  4. pmc Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma
    Jeffrey P North
    UCSF School of Medicine, University of California, San Francisco, California, USA
    J Invest Dermatol 128:2024-30. 2008
  5. ncbi Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool
    Jurgen Bauer
    Departments of Dermatology and Pathology, UCSF Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94143 0808, USA
    Dermatol Ther 19:40-9. 2006
  6. ncbi Somatic activation of KIT in distinct subtypes of melanoma
    John A Curtin
    Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143 0808, USA
    J Clin Oncol 24:4340-6. 2006
  7. pmc Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway
    Janet L Maldonado
    Department of Dermatology, University of California, San Francisco, California 94143, USA
    Am J Pathol 164:1783-7. 2004
  8. ncbi Molecular genetics of melanocytic neoplasia: practical applications for diagnosis
    Boris C Bastian
    Department of Dermatology, University of California, San Francisco, CA 94143, USA
    Pathology 36:458-61. 2004
  9. pmc KIT as a therapeutic target in melanoma
    Maria C Garrido
    Department of Dermatology and UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
    J Invest Dermatol 130:20-7. 2010
  10. doi An unconventional deep penetrating melanocytic nevus with microscopic involvement of regional lymph nodes
    Timothy H McCalmont
    Department of Pathology, University of California, San Francisco, CA, USA
    J Cutan Pathol 39:25-8. 2012

Collaborators

Detail Information

Publications14

  1. doi The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia
    Boris C Bastian
    Departments of Dermatology and Pathology, Cardiovascular Research Institute, University of California, San Francisco, California 94158 9001 email
    Annu Rev Pathol 9:239-71. 2014
    ..The current knowledge about the pathogenesis and clinical, histologic, and genetic features of primary melanocytic neoplasms is reviewed and integrated into a taxonomic framework. ..
  2. ncbi Distinct sets of genetic alterations in melanoma
    John A Curtin
    Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143 0808, USA
    N Engl J Med 353:2135-47. 2005
    ..We hypothesized that the clinical heterogeneity is explained by genetically distinct types of melanoma with different susceptibility to ultraviolet light...
  3. ncbi Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases
    Jeffrey P North
    Departments of Pathology Dermatology The Helen Diller Comprehensive Cancer Center, University of California, San Francisco, CA
    Am J Surg Pathol 38:824-31. 2014
    ..We conclude that FISH testing can help reduce the number of equivocal diagnoses in ambiguous melanocytic neoplasms, in particular if FISH testing is positive, and discuss the challenges and limitations of FISH in clinical practice. ..
  4. pmc Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma
    Jeffrey P North
    UCSF School of Medicine, University of California, San Francisco, California, USA
    J Invest Dermatol 128:2024-30. 2008
    ..These field cells provide a plausible explanation for the tendency of certain melanoma types to recur locally despite apparently having undergone complete excision...
  5. ncbi Distinguishing melanocytic nevi from melanoma by DNA copy number changes: comparative genomic hybridization as a research and diagnostic tool
    Jurgen Bauer
    Departments of Dermatology and Pathology, UCSF Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94143 0808, USA
    Dermatol Ther 19:40-9. 2006
    ..In addition to potential diagnostic applications, detailed analyses of recurrent aberrations can lead to the identification of genes relevant in melanocytic neoplasia...
  6. ncbi Somatic activation of KIT in distinct subtypes of melanoma
    John A Curtin
    Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143 0808, USA
    J Clin Oncol 24:4340-6. 2006
    ..This raises the question of whether other aberrations are occurring in the MAP kinase cascade in the melanoma types with infrequent mutations of BRAF and NRAS...
  7. pmc Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway
    Janet L Maldonado
    Department of Dermatology, University of California, San Francisco, California 94143, USA
    Am J Pathol 164:1783-7. 2004
    ..We propose that in benign nevi with constitutive activation of the MAP-kinase pathway, p16 functions as an essential mediator of oncogene-induced senescence preventing progression to melanoma...
  8. ncbi Molecular genetics of melanocytic neoplasia: practical applications for diagnosis
    Boris C Bastian
    Department of Dermatology, University of California, San Francisco, CA 94143, USA
    Pathology 36:458-61. 2004
    ..This article reviews recent molecular studies that have revealed differences in the pattern of chromosomal aberrations between naevi and melanoma that could become relevant as adjunctive diagnostic methods in the future...
  9. pmc KIT as a therapeutic target in melanoma
    Maria C Garrido
    Department of Dermatology and UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
    J Invest Dermatol 130:20-7. 2010
    ....
  10. doi An unconventional deep penetrating melanocytic nevus with microscopic involvement of regional lymph nodes
    Timothy H McCalmont
    Department of Pathology, University of California, San Francisco, CA, USA
    J Cutan Pathol 39:25-8. 2012
    ..The illustrations are duplicated in both versions of the manuscript but the captions are not the same. The reader is encouraged to study both versions of the manuscript and consider the issue from both perspectives...
  11. ncbi Determinants of BRAF mutations in primary melanomas
    Janet L Maldonado
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA
    J Natl Cancer Inst 95:1878-90. 2003
    ..The high mutation frequency in melanomas arising on intermittently sun-exposed skin suggests a complex causative role of such exposure that mandates further evaluation...
  12. ncbi Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer
    Boris C Bastian
    Departments of Dermatology and Pathology, UCSF Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94115, USA
    Oncogene 22:3081-6. 2003
    ..Genomic analysis is a powerful tool to obtain insight in the progression of melanocytic neoplasms with potential clinical applications for classification and detection of minimal residual melanoma...
  13. pmc Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia
    Iwei Yeh
    Department of Dermatology, University of California, San Francisco, USA
    J Natl Cancer Inst 105:917-9. 2013
    ..We found BRAF(V600E) mutations in the melanocytic nevi to be fully clonal, strongly suggesting that BRAF-activating mutations typically are early initiating events in melanocytic neoplasia...
  14. pmc MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells
    Jesse Lyons
    Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    Proc Natl Acad Sci U S A 110:13845-50. 2013
    ..These results show that MC1R and cAMP signaling can directly inhibit melanoma growth through regulation of the G2/M checkpoint. ..