John R Basile

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc Plexin-B1 activates NF-κB and IL-8 to promote a pro-angiogenic response in endothelial cells
    Ying Hua Yang
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland, United States of America
    PLoS ONE 6:e25826. 2011
  2. doi request reprint A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e28-33. 2010
  3. doi request reprint Calcifying odontogenic cyst with odontogenic keratocyst: a case report and review of the literature
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e40-5. 2010
  4. pmc The hypoxia-inducible factor-responsive proteins semaphorin 4D and vascular endothelial growth factor promote tumor growth and angiogenesis in oral squamous cell carcinoma
    Hua Zhou
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Exp Cell Res 318:1685-98. 2012
  5. pmc Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner
    Nada O Binmadi
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201, USA
    Am J Pathol 180:1232-42. 2012
  6. pmc Hypoxia-inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity
    Qiangming Sun
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201, USA
    J Biol Chem 284:32066-74. 2009
  7. pmc Angiopoietin-like 4: a novel molecular hallmark in oral Kaposi's sarcoma
    Jiadi Hu
    Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA
    Oral Oncol 47:371-5. 2011
  8. ncbi request reprint Rho-mediated activation of PI(4)P5K and lipid second messengers is necessary for promotion of angiogenesis by Semaphorin 4D
    Nada O Binmadi
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, 21201, USA
    Angiogenesis 14:309-19. 2011
  9. pmc Semaphorin 4D cooperates with VEGF to promote angiogenesis and tumor progression
    Hua Zhou
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, 650 West Baltimore Street, 7 North, Baltimore, MD 21201, USA
    Angiogenesis 15:391-407. 2012
  10. pmc Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School Baltimore, MD, USA Marlene and Stuart Greenebaum Cancer Center, University of Maryland Baltimore, MD, USA
    Front Cell Neurosci 7:69. 2013

Collaborators

Detail Information

Publications15

  1. pmc Plexin-B1 activates NF-κB and IL-8 to promote a pro-angiogenic response in endothelial cells
    Ying Hua Yang
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland, United States of America
    PLoS ONE 6:e25826. 2011
    ....
  2. doi request reprint A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e28-33. 2010
    ..The diagnostic dilemma presented by this lesion is discussed, along with a differential diagnosis and brief review of the literature...
  3. doi request reprint Calcifying odontogenic cyst with odontogenic keratocyst: a case report and review of the literature
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e40-5. 2010
    ..The occurrence of 2 "cystic neoplasms" in the same patient is an occurrence which to our knowledge has not been previously reported. We discuss the significance of the case and review the current literature regarding these lesions...
  4. pmc The hypoxia-inducible factor-responsive proteins semaphorin 4D and vascular endothelial growth factor promote tumor growth and angiogenesis in oral squamous cell carcinoma
    Hua Zhou
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, MD 21201, USA
    Exp Cell Res 318:1685-98. 2012
    ..We use blocking antibodies to show that targeting SEMA4D function along with VEGF could represent a novel anti-angiogenic therapeutic strategy for the treatment of OSCC and other solid tumors...
  5. pmc Plexin-B1 and semaphorin 4D cooperate to promote perineural invasion in a RhoA/ROK-dependent manner
    Nada O Binmadi
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201, USA
    Am J Pathol 180:1232-42. 2012
    ..We also demonstrate that nerves are attracted to tumors through this same system of proteins, suggesting that both plexin-B1 and semaphorin 4D are important in the promotion of PNI...
  6. pmc Hypoxia-inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity
    Qiangming Sun
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201, USA
    J Biol Chem 284:32066-74. 2009
    ..Expression of Sema4D may be a strategy by which carcinomas promote angiogenesis and therefore could represent a therapeutic target for these malignancies...
  7. pmc Angiopoietin-like 4: a novel molecular hallmark in oral Kaposi's sarcoma
    Jiadi Hu
    Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA
    Oral Oncol 47:371-5. 2011
    ..These surprising results support a key role for ANGPTL4 in Kaposi's sarcomagenesis and further suggest that this angiogenic factor may provide a novel diagnostic and therapeutic marker for oral KS patients...
  8. ncbi request reprint Rho-mediated activation of PI(4)P5K and lipid second messengers is necessary for promotion of angiogenesis by Semaphorin 4D
    Nada O Binmadi
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, 21201, USA
    Angiogenesis 14:309-19. 2011
    ..Taken together, these results suggest that Plexin-B1 promotes angiogenesis in endothelial cells by signaling through PI(4)P5Kα and generating lipid second messengers...
  9. pmc Semaphorin 4D cooperates with VEGF to promote angiogenesis and tumor progression
    Hua Zhou
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, 650 West Baltimore Street, 7 North, Baltimore, MD 21201, USA
    Angiogenesis 15:391-407. 2012
    ....
  10. pmc Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells
    John R Basile
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School Baltimore, MD, USA Marlene and Stuart Greenebaum Cancer Center, University of Maryland Baltimore, MD, USA
    Front Cell Neurosci 7:69. 2013
    ....
  11. doi request reprint Perineural invasion in oral squamous cell carcinoma: a discussion of significance and review of the literature
    Nada O Binmadi
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, 650 West Baltimore Street, 7 North, Baltimore, MD 21201, USA
    Oral Oncol 47:1005-10. 2011
    ....
  12. doi request reprint Differential expression of organic cation transporter OCT-3 in oral premalignant and malignant lesions: potential implications in the antineoplastic effects of metformin
    Harsh Patel
    Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, MD, USA
    J Oral Pathol Med 42:250-6. 2013
    ....
  13. doi request reprint Semaphorins in vascular development and head and neck squamous cell carcinoma-induced angiogenesis
    Qiangming Sun
    Department of Diagnostic Sciences and Pathology, University of Maryland Dental School, 650 West Baltimore Street, Baltimore, MD 21201, USA
    Oral Oncol 44:523-31. 2008
    ....
  14. pmc The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4
    Hua Zhou
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, 650 West Baltimore Street, 7 North, Baltimore, MD, 21201, USA
    Angiogenesis 17:261-74. 2014
    ....
  15. pmc Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma
    Tao Ma
    Department of Oncology and Diagnostic Sciences, University of Maryland, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 107:14363-8. 2010
    ..As angiogenesis and increased vessel permeability are common themes in all solid tumors, these findings may have a broad impact on our understanding and treatment of cancer...

Research Grants2

  1. The Role of Semaphorin 4D and Plexin-B1 in Tumor-Induced Angiogenesis.
    John Basile; Fiscal Year: 2009
    ..If successful, our proposed project may uncover an important mechanism for tumor-induced angiogenesis, thereby presenting new targets for the development of anti- angiogenic therapies for the management of aggressive tumors. ..
  2. The Role of Semaphorin 4D and Plexin-B1 in Tumor-Induced Angiogenesis.
    John R Basile; Fiscal Year: 2010
    ..If successful, our proposed project may uncover an important mechanism for tumor-induced angiogenesis, thereby presenting new targets for the development of anti- angiogenic therapies for the management of aggressive tumors. ..