Franco Basile

Summary

Affiliation: University of Wyoming
Country: USA

Publications

  1. ncbi request reprint Interface for direct and continuous sample-matrix deposition onto a MALDI probe for polymer analysis by thermal field flow fractionation and off-line MALDI-MS
    Franco Basile
    Department of Chemistry, Colorado School of Mines, Golden, Colorado 80401, USA
    Anal Chem 77:3008-12. 2005
  2. doi request reprint Atmospheric pressure-thermal desorption (AP-TD)/electrospray ionization-mass spectrometry for the rapid analysis of Bacillus spores
    Franco Basile
    Department of Chemistry, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
    Analyst 135:797-803. 2010
  3. pmc Analysis of lipids from crude lung tissue extracts by desorption electrospray ionization mass spectrometry and pattern recognition
    Franco Basile
    Department of Chemistry, University Wyoming, Laramie, WY 82071, USA
    Anal Biochem 408:289-96. 2011
  4. pmc Rapid online nonenzymatic protein digestion combining microwave heating acid hydrolysis and electrochemical oxidation
    Franco Basile
    Department of Chemistry, 1000 East University Avenue Department 3838, University of Wyoming, Laramie, Wyoming 82071, United States
    Anal Chem 83:359-67. 2011
  5. pmc Mass spectrometry characterization of the thermal decomposition/digestion (TDD) at cysteine in peptides and proteins in the condensed phase
    Franco Basile
    Department of Chemistry, University of Wyoming, 1000 University Ave, Laramie, WY 82071, USA
    J Am Soc Mass Spectrom 22:1926-40. 2011
  6. pmc Desorption electrospray ionization-mass spectrometry of proteins
    Yong Seung Shin
    Department of Chemistry, Arthropod Borne Animal Diseases Research Laboratory, ARS, USDA, and School of Pharmacy, University of Wyoming, 1000 East University Avenue, Laramie, Wyoming 82071, USA
    Anal Chem 79:3514-8. 2007
  7. doi request reprint Online microwave D-cleavage LC-ESI-MS/MS of intact proteins: site-specific cleavages at aspartic acid residues and disulfide bonds
    Nicolas J Hauser
    Department of Chemistry, University of Wyoming, Laramie, Wyoming 82071, USA
    J Proteome Res 7:1012-26. 2008
  8. pmc Electron transfer dissociation of peptides generated by microwave D-cleavage digestion of proteins
    Nicolas J Hauser
    Department of Chemistry, University of Wyoming, Laramie, WY 82071, USA
    J Proteome Res 7:1867-72. 2008
  9. pmc Site-specific pyrolysis-induced cleavage at aspartic acid residue in peptides and proteins
    Shaofeng Zhang
    Department of Chemistry, University of Wyoming, Laramie, Wyoming 82071, USA
    J Proteome Res 6:1700-4. 2007

Research Grants

Collaborators

  • Nicolas J Hauser
  • Shaofeng Zhang
  • Yong Seung Shin
  • Hongling Han
  • Scott A McLuckey
  • Kurt Dolence
  • Barbara Drolet
  • Richard Mayer

Detail Information

Publications9

  1. ncbi request reprint Interface for direct and continuous sample-matrix deposition onto a MALDI probe for polymer analysis by thermal field flow fractionation and off-line MALDI-MS
    Franco Basile
    Department of Chemistry, Colorado School of Mines, Golden, Colorado 80401, USA
    Anal Chem 77:3008-12. 2005
    ..The OCN interface is easy to build and operate without the use of heaters or high voltages and is compatible with any MALDI probe format...
  2. doi request reprint Atmospheric pressure-thermal desorption (AP-TD)/electrospray ionization-mass spectrometry for the rapid analysis of Bacillus spores
    Franco Basile
    Department of Chemistry, University of Wyoming, 1000 E University Ave, Laramie, WY 82071, USA
    Analyst 135:797-803. 2010
    ....
  3. pmc Analysis of lipids from crude lung tissue extracts by desorption electrospray ionization mass spectrometry and pattern recognition
    Franco Basile
    Department of Chemistry, University Wyoming, Laramie, WY 82071, USA
    Anal Biochem 408:289-96. 2011
    ..The DESI-MS approach described here provided a practical and rapid means to analyze tissue samples without extensive extractions and solvent changes...
  4. pmc Rapid online nonenzymatic protein digestion combining microwave heating acid hydrolysis and electrochemical oxidation
    Franco Basile
    Department of Chemistry, 1000 East University Avenue Department 3838, University of Wyoming, Laramie, Wyoming 82071, United States
    Anal Chem 83:359-67. 2011
    ..Preliminary results are presented on the application and utility of this rapid online digestion (total of 6 min of digestion time) on a series of standard peptides and proteins as well as an Escherichia coli protein extract...
  5. pmc Mass spectrometry characterization of the thermal decomposition/digestion (TDD) at cysteine in peptides and proteins in the condensed phase
    Franco Basile
    Department of Chemistry, University of Wyoming, 1000 University Ave, Laramie, WY 82071, USA
    J Am Soc Mass Spectrom 22:1926-40. 2011
    ..The combined thermally induced digestion process at D and C, termed thermal decomposition/digestion (TDD), was observed on several model proteins tested under ambient conditions and the site-specificity of the method confirmed by MS/MS...
  6. pmc Desorption electrospray ionization-mass spectrometry of proteins
    Yong Seung Shin
    Department of Chemistry, Arthropod Borne Animal Diseases Research Laboratory, ARS, USDA, and School of Pharmacy, University of Wyoming, 1000 East University Avenue, Laramie, Wyoming 82071, USA
    Anal Chem 79:3514-8. 2007
    ..Finally, we demonstrated the DESI-MS detection of the bacteriophage MS2 capsid protein from crude samples with minimal sample preparation...
  7. doi request reprint Online microwave D-cleavage LC-ESI-MS/MS of intact proteins: site-specific cleavages at aspartic acid residues and disulfide bonds
    Nicolas J Hauser
    Department of Chemistry, University of Wyoming, Laramie, Wyoming 82071, USA
    J Proteome Res 7:1012-26. 2008
    ..Overall, online protein digestion and identification was achieved in less than 40 min total analysis time, including the chromatographic step...
  8. pmc Electron transfer dissociation of peptides generated by microwave D-cleavage digestion of proteins
    Nicolas J Hauser
    Department of Chemistry, University of Wyoming, Laramie, WY 82071, USA
    J Proteome Res 7:1867-72. 2008
    ....
  9. pmc Site-specific pyrolysis-induced cleavage at aspartic acid residue in peptides and proteins
    Shaofeng Zhang
    Department of Chemistry, University of Wyoming, Laramie, Wyoming 82071, USA
    J Proteome Res 6:1700-4. 2007
    ..This suggests that pyrolysis-induced cleavage at aspartyl residues can be used as a rapid protein digestion procedure for the generation of sequence-specific protein biomarkers...

Research Grants1

  1. Non-Enzymatic Cell Lysis/Protein Digestion Proteomics
    Franco Basile; Fiscal Year: 2005
    ..Advantages anticipated from these studies include the ability to perform high throughput sample preparation for proteomic measurements and its direct effect on the rapid diagnosis of microbial related diseases. ..