Valerie N Barton

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. ncbi PARP1 expression in pediatric central nervous system tumors
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USA
    Pediatr Blood Cancer 53:1227-30. 2009
  2. ncbi Unique molecular characteristics of pediatric myxopapillary ependymoma
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Aurora, CO 80045, USA
    Brain Pathol 20:560-70. 2010
  3. ncbi Aurora kinase A as a rational target for therapy in glioblastoma
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Colorado 80045, USA
    J Neurosurg Pediatr 6:98-105. 2010
  4. ncbi Claudin 6 is a positive marker for atypical teratoid/rhabdoid tumors
    Diane K Birks
    Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Aurora, Colorado, USA
    Brain Pathol 20:140-50. 2010
  5. ncbi Clinical and molecular characteristics of congenital glioblastoma
    Margaret E Macy
    Department of Pediatrics, University of Colorado, Denver, CO, USA
    Neuro Oncol 14:931-41. 2012
  6. ncbi Survey of MicroRNA expression in pediatric brain tumors
    Diane K Birks
    Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Aurora, Colorado 80045, USA
    Pediatr Blood Cancer 56:211-6. 2011
  7. ncbi Immune gene and cell enrichment is associated with a good prognosis in ependymoma
    Andrew M Donson
    Department of Pediatrics, University of Colorado Denver, Mail Stop 8302, P O Box 6511, Aurora, CO 80045, USA
    J Immunol 183:7428-40. 2009
  8. ncbi Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma
    Valerie N Barton
    From the Departments of Pediatrics VNB, AMD, NKF, Neurosurgery DKB, BKK D, MHH, Pathology BKK D, and Neurology, University of Colorado Anschutz Medical Campus BKK D and Children s Hospital Colorado BKK D, MHH, NKF, Aurora, Colorado
    J Neuropathol Exp Neurol 72:442-9. 2013
  9. ncbi Memory deficits in patients with pediatric CNS germ cell tumors
    Greta N Wilkening
    The Children s Hospital, Denver, Aurora, CO, USA
    Pediatr Blood Cancer 57:486-91. 2011

Detail Information

Publications9

  1. ncbi PARP1 expression in pediatric central nervous system tumors
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, USA
    Pediatr Blood Cancer 53:1227-30. 2009
    ..Poly(ADP-ribose) polymerase-1 (PARP1) is a DNA repair protein that has been studied in a variety of malignancies and may interfere with therapy-induced DNA damage, however expression in pediatric CNS tumors is unknown...
  2. ncbi Unique molecular characteristics of pediatric myxopapillary ependymoma
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Aurora, CO 80045, USA
    Brain Pathol 20:560-70. 2010
    ..Aberrant expression of HOXB13 suggests possible recapitulation of developmental pathways in MEPN tumorigenesis. PDGFR alpha may be a potential therapeutic target in recurrent MEPN...
  3. ncbi Aurora kinase A as a rational target for therapy in glioblastoma
    Valerie N Barton
    Department of Pediatrics, Anschutz Medical Campus, University of Colorado Denver, Colorado 80045, USA
    J Neurosurg Pediatr 6:98-105. 2010
    ..It was hypothesized that inhibition of a molecular target associated with poor outcome would impact glioblastoma cell proliferation...
  4. ncbi Claudin 6 is a positive marker for atypical teratoid/rhabdoid tumors
    Diane K Birks
    Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Aurora, Colorado, USA
    Brain Pathol 20:140-50. 2010
    ..IHC staining results closely matched the level of mRNA expression detected by microarray. CLDN6 may be a useful positive marker to help further identify AT/RTs for diagnostic and treatment purposes...
  5. ncbi Clinical and molecular characteristics of congenital glioblastoma
    Margaret E Macy
    Department of Pediatrics, University of Colorado, Denver, CO, USA
    Neuro Oncol 14:931-41. 2012
    ..Further study may determine whether identified gene expression differences contribute to the improved survival seen in these tumors...
  6. ncbi Survey of MicroRNA expression in pediatric brain tumors
    Diane K Birks
    Department of Neurosurgery, Anschutz Medical Campus, University of Colorado at Denver, Aurora, Colorado 80045, USA
    Pediatr Blood Cancer 56:211-6. 2011
    ..The present study provides an initial survey of miRNA expression in pediatric central nervous system (CNS) malignancies including atypical teratoid/rhabdoid tumor, ependymoma, glioblastoma, medulloblastoma, and pilocytic astrocytoma...
  7. ncbi Immune gene and cell enrichment is associated with a good prognosis in ependymoma
    Andrew M Donson
    Department of Pediatrics, University of Colorado Denver, Mail Stop 8302, P O Box 6511, Aurora, CO 80045, USA
    J Immunol 183:7428-40. 2009
    ....
  8. ncbi Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma
    Valerie N Barton
    From the Departments of Pediatrics VNB, AMD, NKF, Neurosurgery DKB, BKK D, MHH, Pathology BKK D, and Neurology, University of Colorado Anschutz Medical Campus BKK D and Children s Hospital Colorado BKK D, MHH, NKF, Aurora, Colorado
    J Neuropathol Exp Neurol 72:442-9. 2013
    ..45; p = 0.016). High IMP3, as assessed by immunohistochemistry, has potential use as an additional predictor of poor prognosis in pediatric PA/PMAs and warrants evaluation in larger cohorts...
  9. ncbi Memory deficits in patients with pediatric CNS germ cell tumors
    Greta N Wilkening
    The Children s Hospital, Denver, Aurora, CO, USA
    Pediatr Blood Cancer 57:486-91. 2011
    ..Although case studies suggest that memory deficits may be associated with GCT, this is the first study to investigate memory function across a series of pediatric intracranial GCT patients...