Patrick Barth

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Accurate, conformation-dependent predictions of solvent effects on protein ionization constants
    P Barth
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3206, USA
    Proc Natl Acad Sci U S A 104:4898-903. 2007
  2. ncbi request reprint Modulating membrane protein stability and association by design
    Patrick Barth
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    Curr Opin Struct Biol 17:460-6. 2007
  3. doi request reprint Targeting metastable coiled-coil domains by computational design
    Patrick Barth
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3220, USA
    J Am Chem Soc 130:12038-44. 2008
  4. pmc Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae
    Matthias Versele
    Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3202, USA
    Mol Biol Cell 15:4568-83. 2004
  5. ncbi request reprint Closing in on the resting state of the Shaker K(+) channel
    Medha M Pathak
    Biophysics Graduate Program, University of California Berkeley, Berkeley, CA 94720, USA
    Neuron 56:124-40. 2007
  6. pmc Toward high-resolution prediction and design of transmembrane helical protein structures
    P Barth
    Department of Biochemistry and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 104:15682-7. 2007
  7. pmc Prediction of membrane protein structures with complex topologies using limited constraints
    P Barth
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 106:1409-14. 2009
  8. ncbi request reprint Solution NMR structure and backbone dynamics of the PsaE subunit of photosystem I from Synechocystis sp. PCC 6803
    Patrick Barth
    Departement de Biologie Joliot Curie, Service de Bioenergetique, CEA de Saclay and URA CNRS 2096, F 91191 Gif sur Yvette Cedex, France
    Biochemistry 41:13902-14. 2002

Collaborators

Detail Information

Publications8

  1. pmc Accurate, conformation-dependent predictions of solvent effects on protein ionization constants
    P Barth
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3206, USA
    Proc Natl Acad Sci U S A 104:4898-903. 2007
    ..FDPB_MF provides a faithful, quantitative assessment of electrostatic interactions in biological macromolecules...
  2. ncbi request reprint Modulating membrane protein stability and association by design
    Patrick Barth
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    Curr Opin Struct Biol 17:460-6. 2007
    ..Consequently, new design strategies are emerging that aim to target and stabilize simple transmembrane helical interfaces...
  3. doi request reprint Targeting metastable coiled-coil domains by computational design
    Patrick Barth
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3220, USA
    J Am Chem Soc 130:12038-44. 2008
    ..Our results validate computational methods to design specific peptide ligands to protein domains lacking intrinsic structural stability and set the stage for functional analysis of Cdc12p coiled coil function in vivo...
  4. pmc Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae
    Matthias Versele
    Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3202, USA
    Mol Biol Cell 15:4568-83. 2004
    ..These data provide novel insights about the connectivity among the five individual septins in functional septin heteropentamers and the organization of septin filaments...
  5. ncbi request reprint Closing in on the resting state of the Shaker K(+) channel
    Medha M Pathak
    Biophysics Graduate Program, University of California Berkeley, Berkeley, CA 94720, USA
    Neuron 56:124-40. 2007
    ..Our models are compatible with a wide body of data and resolve apparent contradictions that previously led to several distinct models of voltage sensing...
  6. pmc Toward high-resolution prediction and design of transmembrane helical protein structures
    P Barth
    Department of Biochemistry and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 104:15682-7. 2007
    ....
  7. pmc Prediction of membrane protein structures with complex topologies using limited constraints
    P Barth
    Department of Biochemistry, University of Washington, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 106:1409-14. 2009
    ....
  8. ncbi request reprint Solution NMR structure and backbone dynamics of the PsaE subunit of photosystem I from Synechocystis sp. PCC 6803
    Patrick Barth
    Departement de Biologie Joliot Curie, Service de Bioenergetique, CEA de Saclay and URA CNRS 2096, F 91191 Gif sur Yvette Cedex, France
    Biochemistry 41:13902-14. 2002
    ..PCC 8009. The plasticity of the connecting loops in the free subunit is compared to that when bound to the PSI and discussed in relation to the insertion process and the function(s) of PsaE...