S P Barros

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Epigenetics: connecting environment and genotype to phenotype and disease
    S P Barros
    Center for Oral and Systemic Diseases, Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, Room 222, CB 7455, Chapel Hill, NC 27599, USA
    J Dent Res 88:400-8. 2009
  2. doi request reprint Therapeutic effect of a topical CCR2 antagonist on induced alveolar bone loss in mice
    S P Barros
    Department of Periodontology, School of Dentistry, University of North Carolina, Chapel Hill, NC, USA
    J Periodontal Res 46:246-51. 2011
  3. pmc Increased TLR4 expression in murine placentas after oral infection with periodontal pathogens
    R M Arce
    University of North Carolina at Chapel Hill, Center for Oral and Systemic Diseases, NC 27709, USA
    Placenta 30:156-62. 2009
  4. pmc Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice
    R M Arce
    Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, NC 27599 7455, USA
    Mol Oral Microbiol 27:373-81. 2012
  5. pmc Characterization of the invasive and inflammatory traits of oral Campylobacter rectus in a murine model of fetoplacental growth restriction and in trophoblast cultures
    R M Arce
    Center for Oral and Systemic Diseases, NC Oral Health Institute, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Reprod Immunol 84:145-53. 2010
  6. ncbi request reprint Bacterial infection promotes DNA hypermethylation
    Y A Bobetsis
    University of North Carolina at Chapel Hill, Center for Oral and Systemic Diseases, Department of Periodontology, UNC School of Dentistry, CB 7455, DRC Rm 222, Chapel Hill, NC 27599 7455, USA
    J Dent Res 86:169-74. 2007
  7. ncbi request reprint Levels of serum interleukin (IL)-6 and gingival crevicular fluid of IL-1beta and prostaglandin E(2) among non-smoking subjects with gingivitis and type 2 diabetes
    O M Andriankaja
    School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7450, USA
    J Periodontol 80:307-16. 2009
  8. pmc Genome-wide association study of periodontal pathogen colonization
    K Divaris
    Department of Pediatric Dentistry, School of Dentistry, University of North Carolina Chapel Hill, 228 Brauer Hall, CB 7450, NC 27599, USA
    J Dent Res 91:21S-28S. 2012
  9. ncbi request reprint Impact of tooth loss on oral and systemic health
    S Offenbacher
    Department of Periodontology, University of North Carolina, School of Dentistry, Chapel Hill, NC, USA
    Gen Dent 60:494-500; quiz p. 501-2. 2012
  10. pmc MicroRNA modulation in obesity and periodontitis
    R Perri
    Department of Periodontology and School of Dentistry, University of North Carolina at Chapel Hill, NC, USA
    J Dent Res 91:33-8. 2012

Collaborators

Detail Information

Publications13

  1. pmc Epigenetics: connecting environment and genotype to phenotype and disease
    S P Barros
    Center for Oral and Systemic Diseases, Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, Room 222, CB 7455, Chapel Hill, NC 27599, USA
    J Dent Res 88:400-8. 2009
    ..The challenge in oral biology will be to understand the mechanisms that modify MVPs in oral tissues and to identify those epigenetic patterns that modify disease pathogenesis or responses to therapy...
  2. doi request reprint Therapeutic effect of a topical CCR2 antagonist on induced alveolar bone loss in mice
    S P Barros
    Department of Periodontology, School of Dentistry, University of North Carolina, Chapel Hill, NC, USA
    J Periodontal Res 46:246-51. 2011
    ..The study objective was to determine the effect of an experimental oral/topical chemokine (C-C motif) receptor 2 (CCR2)-antagonist treatment on alveolar bone loss in a mouse model of Porphyromonas gingivalis-induced periodontitis...
  3. pmc Increased TLR4 expression in murine placentas after oral infection with periodontal pathogens
    R M Arce
    University of North Carolina at Chapel Hill, Center for Oral and Systemic Diseases, NC 27709, USA
    Placenta 30:156-62. 2009
    ....
  4. pmc Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice
    R M Arce
    Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, NC 27599 7455, USA
    Mol Oral Microbiol 27:373-81. 2012
    ..rectus infection, suggesting that placental cytokine activation is likely to be mediated by TLR4 during low birthweight/preterm birth pathogenesis...
  5. pmc Characterization of the invasive and inflammatory traits of oral Campylobacter rectus in a murine model of fetoplacental growth restriction and in trophoblast cultures
    R M Arce
    Center for Oral and Systemic Diseases, NC Oral Health Institute, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Reprod Immunol 84:145-53. 2010
    ..In conclusion, the trophoblast-invasive trait of C. rectus that appears limited to human trophoblasts may play a role in facilitating bacterial translocation and placental inflammation during early gestation...
  6. ncbi request reprint Bacterial infection promotes DNA hypermethylation
    Y A Bobetsis
    University of North Carolina at Chapel Hill, Center for Oral and Systemic Diseases, Department of Periodontology, UNC School of Dentistry, CB 7455, DRC Rm 222, Chapel Hill, NC 27599 7455, USA
    J Dent Res 86:169-74. 2007
    ..This novel finding, correlating infection with epigenetic alterations, provides a mechanism linking environmental signals to placental phenotype, with consequences for development...
  7. ncbi request reprint Levels of serum interleukin (IL)-6 and gingival crevicular fluid of IL-1beta and prostaglandin E(2) among non-smoking subjects with gingivitis and type 2 diabetes
    O M Andriankaja
    School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7450, USA
    J Periodontol 80:307-16. 2009
    ....
  8. pmc Genome-wide association study of periodontal pathogen colonization
    K Divaris
    Department of Pediatric Dentistry, School of Dentistry, University of North Carolina Chapel Hill, 228 Brauer Hall, CB 7450, NC 27599, USA
    J Dent Res 91:21S-28S. 2012
    ..Investigations replicating these findings may lead to an improved understanding of the complex nature of host-microbiome interactions that characterizes states of health and disease...
  9. ncbi request reprint Impact of tooth loss on oral and systemic health
    S Offenbacher
    Department of Periodontology, University of North Carolina, School of Dentistry, Chapel Hill, NC, USA
    Gen Dent 60:494-500; quiz p. 501-2. 2012
    ..albicans to the oral mucosa, or both. Ongoing investigations are attempting to incorporate interventions into matrices, to provide a local and sustained presence to therapeutic interventions...
  10. pmc MicroRNA modulation in obesity and periodontitis
    R Perri
    Department of Periodontology and School of Dentistry, University of North Carolina at Chapel Hill, NC, USA
    J Dent Res 91:33-8. 2012
    ....
  11. ncbi request reprint Periodontal disease at the biofilm-gingival interface
    S Offenbacher
    Center for Oral and Systemic Diseases and Department of Periodontology, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7455, USA
    J Periodontol 78:1911-25. 2007
    ..A molecular epidemiologic study provided the opportunity to characterize the biology of the biofilm-gingival interface (BGI) in 6,768 community-dwelling subjects...
  12. pmc Alteration of PTGS2 promoter methylation in chronic periodontitis
    S Zhang
    Center for Oral and Systemic Diseases, University of North Carolina at Chapel Hill, Durham, 27709, USA
    J Dent Res 89:133-7. 2010
    ..These findings suggest that the chronic persistence of the biofilm and inflammation may be associated with epigenetic changes in local tissues at the biofilm-gingival interface...
  13. ncbi request reprint Effects of maternal Campylobacter rectus infection on murine placenta, fetal and neonatal survival, and brain development
    S Offenbacher
    Center for Oral and Systemic Diseases, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7455, USA
    J Periodontol 76:2133-43. 2005
    ..The objective of this study was to determine whether maternal Campylobacter rectus infection that induces fetal growth restriction in a mouse model also compromises neonatal pup survival, growth, and neurodevelopment...