Susan Barron

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Neonatal ethanol exposure but not neonatal cocaine selectively reduces specific isolation-induced vocalization waveforms in rats
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506, USA
    Behav Genet 35:93-102. 2005
  2. ncbi request reprint Polyamine modulation of NMDARs as a mechanism to reduce effects of alcohol dependence
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506 0044, USA
    Recent Pat CNS Drug Discov 7:129-44. 2012
  3. doi request reprint Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, Kentucky 40506 0044, USA
    Alcohol Clin Exp Res 32:929-36. 2008
  4. ncbi request reprint Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506 0044, USA
    Alcohol Clin Exp Res 29:1720-5. 2005
  5. pmc Agmatine reduces ultrasonic vocalization deficits in female rat pups exposed neonatally to ethanol
    Kristen Wellmann
    Department of Psychology, Kastle Hall, University of Kentucky, Lexington, KY 40506, USA
    Neurotoxicol Teratol 32:158-63. 2010
  6. doi request reprint Topiramate attenuates the stress-induced increase in alcohol consumption and preference in male C57BL/6J mice
    Justin M Farook
    Department of Psychology, University of Kentucky, Lexington, Kentucky 40506, USA
    Physiol Behav 96:189-93. 2009
  7. doi request reprint Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice
    Justin M Farook
    Department of Pharmaceutical Science, University of Kentucky, Lexington, Kentucky 40536, USA
    Physiol Behav 97:503-6. 2009
  8. doi request reprint Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine
    TRACY D STEPANYAN
    Department of Molecular and Biomedical Pharmacology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA
    Alcohol Clin Exp Res 32:2128-35. 2008
  9. pmc Acamprosate attenuates the handling induced convulsions during alcohol withdrawal in Swiss Webster mice
    Justin M Farook
    Department of Psychology, University of Kentucky, Lexington, KY 40506, USA
    Physiol Behav 95:267-70. 2008
  10. ncbi request reprint Smoking kills (alcoholics)! shouldn't we do something about it?
    John Littleton
    College of Pharmacy, University of Kentucky, USA
    Alcohol Alcohol 42:167-73. 2007

Research Grants

  1. Polyamines in neonatal alcohol neurotoxicity
    Susan Barron; Fiscal Year: 2005

Detail Information

Publications17

  1. ncbi request reprint Neonatal ethanol exposure but not neonatal cocaine selectively reduces specific isolation-induced vocalization waveforms in rats
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506, USA
    Behav Genet 35:93-102. 2005
    ..These findings provide further support that neonatal ethanol exposure can have significant effects on maternal/infant communication and may play a role in many of the long-term effects associated with ethanol exposure during development...
  2. ncbi request reprint Polyamine modulation of NMDARs as a mechanism to reduce effects of alcohol dependence
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506 0044, USA
    Recent Pat CNS Drug Discov 7:129-44. 2012
    ..This chapter will present a review of the background and rationale for this approach and some of the findings garnered from this approach as well as patents targeting the glutamatergic system especially the NMDAR...
  3. doi request reprint Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, Kentucky 40506 0044, USA
    Alcohol Clin Exp Res 32:929-36. 2008
    ..Due to changes in NMDAR subtypes and response to polyamines, we predicted that slices taken from PND 2 pups would be more sensitive to EWD and polyamine challenge...
  4. ncbi request reprint Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models
    Susan Barron
    Psychology Department, University of Kentucky, Lexington, KY 40506 0044, USA
    Alcohol Clin Exp Res 29:1720-5. 2005
    ..special? Possible age-related vulnerabilities to chronic alcohol or nicotine exposure," organized by Susan Barron and Linda Spear and held at the 2004 Research Society on Alcoholism Meeting in Vancouver, British Columbia...
  5. pmc Agmatine reduces ultrasonic vocalization deficits in female rat pups exposed neonatally to ethanol
    Kristen Wellmann
    Department of Psychology, Kastle Hall, University of Kentucky, Lexington, KY 40506, USA
    Neurotoxicol Teratol 32:158-63. 2010
    ....
  6. doi request reprint Topiramate attenuates the stress-induced increase in alcohol consumption and preference in male C57BL/6J mice
    Justin M Farook
    Department of Psychology, University of Kentucky, Lexington, Kentucky 40506, USA
    Physiol Behav 96:189-93. 2009
    ..This experiment suggests that one mechanism of topiramate in reducing alcohol consumption and alcohol preference may involve an interaction with stress...
  7. doi request reprint Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice
    Justin M Farook
    Department of Pharmaceutical Science, University of Kentucky, Lexington, Kentucky 40536, USA
    Physiol Behav 97:503-6. 2009
    ..These results provide support that nicotinic receptor based drugs may be useful as potential treatments for alcoholism...
  8. doi request reprint Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine
    TRACY D STEPANYAN
    Department of Molecular and Biomedical Pharmacology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA
    Alcohol Clin Exp Res 32:2128-35. 2008
    ..An exception is the moderate affinity NMDAR channel blocker memantine, used in Alzheimer's dementia. The present studies examined the ability of memantine to protect against EWD-related toxicity in vitro and seizures in vivo...
  9. pmc Acamprosate attenuates the handling induced convulsions during alcohol withdrawal in Swiss Webster mice
    Justin M Farook
    Department of Psychology, University of Kentucky, Lexington, KY 40506, USA
    Physiol Behav 95:267-70. 2008
    ..05). This study supports the use of acamprosate during periods of alcohol withdrawal as well as during abstinence...
  10. ncbi request reprint Smoking kills (alcoholics)! shouldn't we do something about it?
    John Littleton
    College of Pharmacy, University of Kentucky, USA
    Alcohol Alcohol 42:167-73. 2007
    ..Our intention in this opinion overview is to use the current literature to provide a framework for future studies into the impact of alcohol use on the reinforcing effects of nicotine...
  11. pmc Effects of mecamylamine on alcohol consumption and preference in male C57BL/6J mice
    Justin M Farook
    Department of Psychology, College of Pharmacy, University of Kentucky, Lexington, KY 40506, USA
    Pharmacology 83:379-84. 2009
    ..These results provide further support that mecamylamine is effective in reducing alcohol consumption and preference, and nicotinic-receptor-based drugs could further be explored as potential treatments for alcoholism...
  12. ncbi request reprint Topiramate (Topamax) reduces conditioned abstinence behaviours and handling-induced convulsions (HIC) after chronic administration of alcohol in Swiss-Webster mice
    Justin M Farook
    Department of Psychology, Kastle Hall, University of Kentucky, Lexington, Kentucky 40506, USA
    Alcohol Alcohol 42:296-300. 2007
    ..Recent studies have shown that topiramate reduces harmful drinking and initiates abstinence in humans, but little is known as to why this drug is effective...
  13. ncbi request reprint Neonatal ethanol and nicotine exposure causes locomotor activity changes in preweanling animals
    Rebecca J Gilbertson
    Department of Psychology, Kastle Hall, University of Kentucky, Lexington, KY 40506 0044, USA
    Pharmacol Biochem Behav 81:54-64. 2005
    ....
  14. ncbi request reprint Neonatal ethanol exposure produces a hyperalgesia that extends into adolescence, and is associated with increased analgesic and rewarding properties of nicotine in rats
    Dennis T Rogers
    The Kentucky Tobacco Research and Development Center, Cooper and University Drives, Lexington, KY 40506 0236, USA
    Psychopharmacology (Berl) 171:204-11. 2004
    ..Such factors may contribute to the high level of alcohol and nicotine co-abuse in humans...
  15. ncbi request reprint Ethanol and nicotine: a pharmacologic balancing act?
    Mark A Prendergast
    Department of Psychology, University of Kentucky, Lexington 40506 0044, USA
    Alcohol Clin Exp Res 26:1917-8. 2002
  16. ncbi request reprint Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats
    Carlos Fernando Mello
    Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, Santa Maria, Brazil
    Alcohol Clin Exp Res 31:887-94. 2007
    ..However, it is not known if early ethanol exposure causes long-lasting protein oxidative damage and if polyamines play a role in such a deleterious effect of ethanol...
  17. ncbi request reprint Effects of neonatal alcohol and/or cocaine exposure on stress in juvenile and adult female rats
    Lynne S Hansen-Trench
    Box 549007, Birmingham Southern College, 900 Arkadelphia Road, Birmingham, AL 35254, United States
    Neurotoxicol Teratol 27:55-63. 2005
    ..These findings suggest that the forced swim test may be more sensitive to neonatal drug effects than open field, although these effects may not be consistent across age...

Research Grants1

  1. Polyamines in neonatal alcohol neurotoxicity
    Susan Barron; Fiscal Year: 2005
    ..abstract_text> ..