Elizabeth Barrett-Connor

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Mid-life blood pressure levels and the 8-year incidence of type 2 diabetes mellitus: the Rancho Bernardo Study
    C K Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    J Hum Hypertens 24:519-24. 2010
  2. pmc Serum uric acid levels improve prediction of incident type 2 diabetes in individuals with impaired fasting glucose: the Rancho Bernardo Study
    Caroline Kaercher Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Diabetes Care 32:1272-3. 2009
  3. pmc Gender differences and disparities in all-cause and coronary heart disease mortality: epidemiological aspects
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, United States Electronic address
    Best Pract Res Clin Endocrinol Metab 27:481-500. 2013
  4. pmc Menopause, atherosclerosis, and coronary artery disease
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Curr Opin Pharmacol 13:186-91. 2013
  5. pmc The association of concurrent vitamin D and sex hormone deficiency with bone loss and fracture risk in older men: the osteoporotic fractures in men (MrOS) study
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    J Bone Miner Res 27:2306-13. 2012
  6. pmc Five-year stability in associations of health-related quality of life measures in community-dwelling older adults: the Rancho Bernardo Study
    Claudia Der-Martirosian
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0607, La Jolla, CA 92093 0631, USA
    Qual Life Res 19:1333-41. 2010
  7. pmc Peripheral arterial disease and osteoporosis in older adults: the Rancho Bernardo Study
    D Von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, La Jolla, San Diego, CA, USA
    Osteoporos Int 20:2071-8. 2009
  8. ncbi request reprint Raloxifene and risk for stroke based on the framingham stroke risk score
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, Calif 92093 0607, USA
    Am J Med 122:754-61. 2009
  9. pmc Women and heart disease: neglected directions for future research
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, Mail Code 0607, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    J Cardiovasc Transl Res 2:256-7. 2009
  10. ncbi request reprint Osteoporosis and fracture risk in women of different ethnic groups
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0607, USA
    J Bone Miner Res 20:185-94. 2005

Research Grants

  1. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 1999
  2. CVD Predictors of Cognitive Function Trajectory over 20 Years
    Elizabeth Barrett Connor; Fiscal Year: 2007
  3. Osteoporotic Fractures in Men - MrOS Renewal
    Elizabeth Barrett Connor; Fiscal Year: 2007
  4. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2007
  5. Gender differences in Bone Loss and Incident Fractures
    Elizabeth Barrett Connor; Fiscal Year: 2007
  6. CVD Predictors of Cognitive Function Trajectory over 20 Years
    Elizabeth Barrett Connor; Fiscal Year: 2009
  7. Post DPP (Diabetes Prevention Program)
    Elizabeth Barrett Connor; Fiscal Year: 2007
  8. Gender differences in Bone Loss and Incident Fractures
    Elizabeth Barrett Connor; Fiscal Year: 2007
  9. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2000
  10. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2001

Detail Information

Publications147 found, 100 shown here

  1. pmc Mid-life blood pressure levels and the 8-year incidence of type 2 diabetes mellitus: the Rancho Bernardo Study
    C K Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    J Hum Hypertens 24:519-24. 2010
    ..In conclusion, mid-life hypertension and prehypertension predicted future diabetes, independent of BMI. Glucose surveillance should be encouraged in adults with prehypertension or hypertension...
  2. pmc Serum uric acid levels improve prediction of incident type 2 diabetes in individuals with impaired fasting glucose: the Rancho Bernardo Study
    Caroline Kaercher Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Diabetes Care 32:1272-3. 2009
    ..To determine whether serum uric acid predicts incident type 2 diabetes by glucose tolerance status in older community-dwelling adults...
  3. pmc Gender differences and disparities in all-cause and coronary heart disease mortality: epidemiological aspects
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, United States Electronic address
    Best Pract Res Clin Endocrinol Metab 27:481-500. 2013
    ....
  4. pmc Menopause, atherosclerosis, and coronary artery disease
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Curr Opin Pharmacol 13:186-91. 2013
    ..Cohort studies suggest that women with oophorectomy are at greater risk for CHD than intact women, pointing to a greater risk from testosterone deficiency than from estradiol levels. ..
  5. pmc The association of concurrent vitamin D and sex hormone deficiency with bone loss and fracture risk in older men: the osteoporotic fractures in men (MrOS) study
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA
    J Bone Miner Res 27:2306-13. 2012
    ..In summary, adverse skeletal effects of low sex steroid levels were more pronounced in older men with low VitD levels. The presence of low VitD in the presence of low BioE/high SHBG may contribute substantially to poor skeletal health...
  6. pmc Five-year stability in associations of health-related quality of life measures in community-dwelling older adults: the Rancho Bernardo Study
    Claudia Der-Martirosian
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0607, La Jolla, CA 92093 0631, USA
    Qual Life Res 19:1333-41. 2010
    ..This study examines the five-year stability of the association of SF-12 and SF-6D scores with scores on the longer SF-36 and its domains in community-dwelling older men and women...
  7. pmc Peripheral arterial disease and osteoporosis in older adults: the Rancho Bernardo Study
    D Von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, La Jolla, San Diego, CA, USA
    Osteoporos Int 20:2071-8. 2009
    ..We found a weak association between PAD and osteoporosis and bone loss only in women, but the association was not independent of age. PAD was not associated with fractures in this community-based population...
  8. ncbi request reprint Raloxifene and risk for stroke based on the framingham stroke risk score
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, Calif 92093 0607, USA
    Am J Med 122:754-61. 2009
    ..We assessed whether this risk is concentrated in postmenopausal women already at high stroke risk...
  9. pmc Women and heart disease: neglected directions for future research
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, Mail Code 0607, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    J Cardiovasc Transl Res 2:256-7. 2009
    ..Where, beyond estrogen therapy, should we go from here to explain the striking sex differences in heart disease rates? A broader spectrum of research about the female cardiovascular advantage and its translation is needed...
  10. ncbi request reprint Osteoporosis and fracture risk in women of different ethnic groups
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0607, USA
    J Bone Miner Res 20:185-94. 2005
    ..Weight explained differences in BMD, except among blacks, who had the highest BMD. One SD decrease in BMD predicted a 50% increased fracture risk in each group. Despite similar relative risks, absolute fracture rates differed...
  11. ncbi request reprint Recency and duration of postmenopausal hormone therapy: effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) study
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Menopause 10:412-9. 2003
    ....
  12. ncbi request reprint Clinical review 162: cardiovascular endocrinology 3: an epidemiologist looks at hormones and heart disease in women
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
    J Clin Endocrinol Metab 88:4031-42. 2003
  13. ncbi request reprint Post hoc analysis of data from the Multiple Outcomes of Raloxifene Evaluation (MORE) trial on the effects of three years of raloxifene treatment on glycemic control and cardiovascular disease risk factors in women with and without type 2 diabetes
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, School of Medicine, University of California at San Diego, La Jolla, California 92093 0607, USA
    Clin Ther 25:919-30. 2003
    ..The long-term effects of the selective estrogen-receptor modulator raloxifene hydrochloride on glycemic control and markers of cardiovascular disease risk in postmenopausal women with type 2 diabetes mellitus are unknown...
  14. ncbi request reprint Hormones and heart disease in women: where are we in 2005?
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Curr Atheroscler Rep 8:85-7. 2006
  15. ncbi request reprint Association of serum proinsulin with hormone replacement therapy in nondiabetic older women: the Rancho Bernardo Study
    Dong Jun Kim
    Department of FamilyPreventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Diabetes Care 29:618-24. 2006
    ..We report here the association of HRT with proinsulin, insulin, and fasting and postchallenge glucose levels in older adults...
  16. pmc A1C and diabetes diagnosis: The Rancho Bernardo Study
    Caroline K Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Diabetes Care 33:101-3. 2010
    ..To examine the sensitivity and specificity of A1C as a diagnostic test for type 2 diabetes in older adults...
  17. ncbi request reprint Hormone therapy and coronary artery calcification in asymptomatic postmenopausal women: the Rancho Bernardo Study
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, School of Medicine, Mail Code 0607, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Menopause 12:40-8. 2005
    ....
  18. ncbi request reprint Risk-benefit profile for raloxifene: 4-year data From the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California at San Diego, La Jolla, California 92093 0607, USA
    J Bone Miner Res 19:1270-5. 2004
    ..39% and 1.83% in the raloxifene and placebo groups, respectively (HR, 0.75; 95% CI, 0.62-0.92), compatible with a favorable risk-benefit profile for raloxifene for treating postmenopausal osteoporosis...
  19. ncbi request reprint Male testosterone: what is normal?
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
    Clin Endocrinol (Oxf) 62:263-4. 2005
  20. ncbi request reprint The rise and fall of menopausal hormone therapy
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, 92093 0607, USA
    Annu Rev Public Health 26:115-40. 2005
    ..Differences between EPT and ET may reflect chance, baseline differences between the EPT and ET cohorts, or a progestin effect. Studies of younger women and lower HT doses with intermediate endpoints are beginning...
  21. ncbi request reprint Commentary: observation versus intervention--what's different?
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Int J Epidemiol 33:457-9. 2004
  22. pmc Alendronate and atrial fibrillation: a meta-analysis of randomized placebo-controlled clinical trials
    E Barrett-Connor
    University of California, San Diego, La Jolla, CA, USA
    Osteoporos Int 23:233-45. 2012
    ..Across all studies, no clear association between overall bisphosphonate exposure and the rate of serious or non-serious AF was observed...
  23. ncbi request reprint Cardiovascular risk stratification and cardiovascular risk factors associated with erectile dysfunction: assessing cardiovascular risk in men with erectile dysfunction
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
    Clin Cardiol 27:I8-13. 2004
    ..Early detection of ED may allow for early diagnosis and management of CVD and diabetes...
  24. doi request reprint Treatment satisfaction and persistence among postmenopausal women on osteoporosis medications: 12-month results from POSSIBLE US™
    E Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Osteoporos Int 23:733-41. 2012
    ..Lower satisfaction among women with moderate/severe side effects increased the risk of discontinuation/switching by 67%. Treatment satisfaction and side effect experience influence osteoporosis medication adherence...
  25. ncbi request reprint Heart disease risk factors predict erectile dysfunction 25 years later (the Rancho Bernardo Study)
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Am J Cardiol 96:3M-7M. 2005
    ..In all, 1 in 5 men had > or =3 risk factors and were at a 2.2-fold increased risk of ED. Improving CAD risk factors in midlife may decrease ED risk as well as CAD risk...
  26. ncbi request reprint Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    N Engl J Med 355:125-37. 2006
    ..The effect of raloxifene, a selective estrogen-receptor modulator, on coronary heart disease (CHD) and breast cancer is not established...
  27. pmc Heart disease risk factors in midlife predict subclinical coronary atherosclerosis more than 25 years later in survivors without clinical heart disease: the Rancho Bernardo Study
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0607, La Jolla, CA 92093, USA
    J Am Geriatr Soc 57:1041-4. 2009
    ..To determine which of the classic modifiable coronary heart disease (CHD) risk factors, measured in midlife, are associated with subclinical coronary atherosclerosis in older age...
  28. pmc Epidemiology of rib fractures in older men: Osteoporotic Fractures in Men (MrOS) prospective cohort study
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    BMJ 340:c1069. 2010
    ..To study the causes and consequences of radiologically confirmed rib fractures (seldom considered in the context of osteoporosis) in community dwelling older men...
  29. ncbi request reprint Raloxifene: risks and benefits
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093, USA
    Ann N Y Acad Sci 949:295-303. 2001
    ..This paper reviews the clinical trial evidence for raloxifene benefits and risks, and how they compare with those of hormone replacement therapy (HRT) and relate to the choices of postmenopausal women...
  30. ncbi request reprint Hormones and the health of women: past, present, and future. Keynote address
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Menopause 9:23-31. 2002
    ..Future uses of sex hormones are likely to be viewed as overmedicalization initially, and time will tell whether these uses are healthy or merely controversial...
  31. ncbi request reprint Hormones and heart disease in women: the timing hypothesis
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, CA, USA
    Am J Epidemiol 166:506-10. 2007
    ..In the meantime, publicized statements in multiple venues have promoted the timing hypothesis as fact, confusing patients and physicians who do not realize that the hypothesis is stronger than the evidence...
  32. ncbi request reprint Hormones and heart disease in women: Heart and Estrogen/Progestin Replacement Study in perspective
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    J Clin Endocrinol Metab 84:1848-53. 1999
    ..Women who are undecided should be asked to consider participation in clinical trials. The HERS has dramatically illustrated the need for them...
  33. ncbi request reprint Isolated postchallenge hyperglycemia and the risk of fatal cardiovascular disease in older women and men. The Rancho Bernardo Study
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    Diabetes Care 21:1236-9. 1998
    ..1 mmol/l with fasting plasma glucose [FPG] < 7.0 mmol/l) increases the risk of fatal cardiovascular disease (CVD) in older women and men...
  34. ncbi request reprint Hormone replacement therapy, heart disease, and other considerations
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    Annu Rev Public Health 19:55-72. 1998
    ..Therefore, until findings from randomized trials confirm and quantitate the benefit of estrogen therapy for prevention of CHD, we believe it should not be recommended to all postmenopausal women...
  35. ncbi request reprint NIDDM, impaired glucose tolerance, and pulmonary function in older adults. The Rancho Bernardo Study
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    Diabetes Care 19:1441-4. 1996
    ..To determine whether NIDDM or plasma glucose level in subjects without diabetes is associated with reduced pulmonary function in 525 men and 714 women, 51-95 years of age...
  36. ncbi request reprint Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego School of Medicine, 9500 Gilman Dr, No 0607, La Jolla, CA 92093 0607, USA
    JAMA 287:847-57. 2002
    ..Raloxifene, a selective estrogen receptor modulator, improves cardiovascular risk factors, but its effect on cardiovascular events is unknown...
  37. doi request reprint Design of the POSSIBLE UStrade mark Study: postmenopausal women's compliance and persistence with osteoporosis medications
    E Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Osteoporos Int 20:463-72. 2009
    ..We report our study design and the baseline characteristics of 4,994 postmenopausal women recruited from primary care physician offices in 33 states...
  38. ncbi request reprint Wrist fracture as a predictor of future fractures in younger versus older postmenopausal women: results from the National Osteoporosis Risk Assessment (NORA)
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Osteoporos Int 19:607-13. 2008
    ..This 3-year follow-up study of 158,940 women showed a similar future fracture risk in younger and older women with wrist-fracture history...
  39. pmc Endogenous and exogenous estrogen, cognitive function, and dementia in postmenopausal women: evidence from epidemiologic studies and clinical trials
    Elizabeth Barrett-Connor
    Departments of Family and Preventive Medicine and Medicine, University of California, San Diego School of Medicine, La Jolla, California 92093 0607, USA
    Semin Reprod Med 27:275-82. 2009
    ..Overall, the evidence does not convincingly support the prescription of early or late postmenopausal estrogen therapy to preserve cognitive function or prevent dementia...
  40. ncbi request reprint Endogenous sex hormones and cognitive function in older men
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    J Clin Endocrinol Metab 84:3681-5. 1999
    ..Linear and nonlinear associations were also found, suggesting that an optimal level of sex hormones may exist for some cognitive functions...
  41. ncbi request reprint Coronary artery calcium versus intima-media thickness as a measure of cardiovascular disease among asymptomatic adults (from the Rancho Bernardo Study)
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Am J Cardiol 99:227-31. 2007
    ..In conclusion, IMT of the carotid arteries predicted the severity of CAC burden an average of 3 years later in community-dwelling asymptomatic older adults...
  42. ncbi request reprint Does hyperinsulinemia preserve bone?
    E Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    Diabetes Care 19:1388-92. 1996
    ..Obesity and NIDDM are each associated with increased bone mineral density (BMD). We therefore hypothesize that hyperinsulinemia is an osteogenic factor...
  43. pmc Women and cardiovascular disease
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, La Jolla, Calif 92093 0607, USA
    CMAJ 176:791-3. 2007
  44. pmc The association of testosterone levels with overall sleep quality, sleep architecture, and sleep-disordered breathing
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0607, USA
    J Clin Endocrinol Metab 93:2602-9. 2008
    ....
  45. ncbi request reprint An introduction to obesity and dementia
    Elizabeth Barrett-Connor
    Department of Family and Preventive Medicine, University of California, San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Curr Alzheimer Res 4:97-101. 2007
    ..If any of these factors are in the causal pathway to dementia, their reversal or prevention by weight control would have huge public health importance...
  46. ncbi request reprint Commentary: Masculinity, femininity and heart disease
    Elizabeth Barrett-Connor
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Int J Epidemiol 36:621-2. 2007
  47. pmc Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk
    Deborah Grady
    University of California, San Francisco, and San Francisco VA Medical Center, San Francisco, CA 94115, USA
    J Natl Cancer Inst 100:854-61. 2008
    ..Here, we provide further details about breast cancer incidence by tumor characteristics, duration of treatment, and subgroup...
  48. pmc Associations of pericardial and intrathoracic fat with coronary calcium presence and progression in a multiethnic study
    Christina L Wassel
    Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 21:1704-12. 2013
    ..Ectopic adipose depots may provide a more refined representation of the role of adiposity in CVD. Thus, the association of pericardial and intra-thoracic fat with coronary artery calcium (CAC) was examined...
  49. pmc Individual and neighborhood socioeconomic status and inflammation in Mexican American women: what is the role of obesity?
    Linda C Gallo
    Department of Psychology, San Diego StateUniversity, San Diego, CA, USA
    Psychosom Med 74:535-42. 2012
    ..We examined relationships of individual and neighborhood SES with inflammatory markers in Mexican American women and evaluated contributions of obesity and related heath behaviors to these associations...
  50. ncbi request reprint Subclinical coronary atherosclerosis in asymptomatic Filipino and white women
    Maria Rosario G Araneta
    Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Dr, 0607, La Jolla, CA 92093, USA
    Circulation 110:2817-23. 2004
    ..Few studies have described EBCT-defined CHD among ethnic minorities with elevated T2DM prevalence. The objective of this study was to compare EBCT-defined CAC in Filipino and white women without known cardiovascular disease...
  51. ncbi request reprint Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trial
    Alka M Kanaya
    Division of General Internal Medicine, University of California, San Francisco, 1701 Divisadero Street, Suite 536, San Francisco, CA 94143 1732, USA
    Ann Intern Med 138:1-9. 2003
    ..Randomized trials of postmenopausal hormone therapy have found differing effects on fasting glucose levels. No trial has evaluated the effect of hormone therapy on diabetes incidence...
  52. ncbi request reprint Predictors of heart failure among women with coronary disease
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA 94143 1364, USA
    Circulation 110:1424-30. 2004
    ..We determined the risk factors for developing heart failure among postmenopausal women with established coronary disease...
  53. ncbi request reprint Serum insulin-like growth factor binding protein-1 levels and bone mineral density in older adults: the Rancho Bernardo Study
    Simerjot K Jassal
    Department of Medicine, University of California San Diego and VA San Diego Healthcare System, La Jolla, CA, USA
    Osteoporos Int 16:1948-54. 2005
    ..Studies are needed to further investigate the relationship between inhibitory components of IGF-1 and bone loss...
  54. pmc Elevated natriuretic peptide levels and cognitive function in community-dwelling older adults
    Lori B Daniels
    Division of Cardiology, Department of Medicine, University of California at San Diego, USA
    Am J Med 124:670.e1-8. 2011
    ..We assessed the association between N-terminal pro B-type natriuretic peptide (NT-proBNP) levels and cognitive function in community-dwelling ambulatory older adults in the Rancho Bernardo Study...
  55. ncbi request reprint Modifiable predictors of bone loss in older men: a prospective study
    Ludmila N Bakhireva
    University of California, San Diego, Department of Family and Preventive Medicine, Division of Epidemiology, La Jolla, California 92093 0607, USA
    Am J Prev Med 26:436-42. 2004
    ..This prospective study describes the patterns of BMD change at the hip and spine, incidence of osteoporosis, and modifiable predictors of bone loss in 507 ambulatory community-dwelling men aged 45 to 92 years...
  56. pmc Walking decreased risk of cardiovascular disease mortality in older adults with diabetes
    Tyler C Smith
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive 0607, La Jolla, CA 92093 0607, USA
    J Clin Epidemiol 60:309-17. 2007
    ..This study examines the association of walking with mortality in persons with type 2 diabetes compared to those with normal glucose tolerance...
  57. doi request reprint Is diabetes mellitus a heart disease equivalent in women? Results from an international study of postmenopausal women in the Raloxifene Use for the Heart (RUTH) Trial
    Lori B Daniels
    Division of Cardiology, University of California San Diego, 9444 Medical Center Dr, La Jolla, CA 92037 7411, USA
    Circ Cardiovasc Qual Outcomes 6:164-70. 2013
    ..The purpose of this study was to determine whether diabetes mellitus is a coronary heart disease (CHD) risk equivalent for prediction of future CHD and CVD events in women...
  58. pmc Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study
    Rohit Loomba
    Division of Gastroenterology and Division of Epidemiology, University of California at San Diego, 9500 Gilman Drive, MC 0063, La Jolla, CA 92093, USA
    Am J Epidemiol 177:333-42. 2013
    ..83, 0.67, and 4.53, respectively, suggesting a multiplicative interaction between alcohol use and obesity. Obesity and alcohol synergistically increase the risk of incident HCC...
  59. pmc Obesity increases and physical activity decreases lower urinary tract symptom risk in older men: the Osteoporotic Fractures in Men study
    J Kellogg Parsons
    Division of Urology, University of California San Diego, San Diego, CA, USA
    Eur Urol 60:1173-80. 2011
    ..Two potential targets for preventing chronic lower urinary tract symptoms (LUTS) in older men are obesity and physical activity...
  60. ncbi request reprint Sex differences in the association between proinsulin and intact insulin with coronary heart disease in nondiabetic older adults: the Rancho Bernardo Study
    Jee Young Oh
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla 92093 0607, USA
    Circulation 105:1311-6. 2002
    ..The role of sex differences in this association is unclear. We examined the cross-sectional association of proinsulin and insulin with CHD in older men and women without diabetes...
  61. doi request reprint Is dairy product consumption associated with the incidence of CHD?
    Elisea E Avalos
    Department of Family and Preventive Medicine, University of California, 9500 Gilman Drive 0628, La Jolla, San Diego, CA 92093 0628, USA
    Public Health Nutr 16:2055-63. 2013
    ..The current prospective study examined the association between dairy consumption and CHD in a population-based sample of older community-dwelling adults...
  62. ncbi request reprint Sex and time differences in the associations of non-high-density lipoprotein cholesterol versus other lipid and lipoprotein factors in the prediction of cardiovascular death (The Rancho Bernardo Study)
    Denise von Muhlen
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 93093 0607, USA
    Am J Cardiol 91:1311-5. 2003
    ..Thus, non-HDL cholesterol is not superior to individual lipids, lipoproteins, or their ratios in the prediction of cardiovascular death in older adults...
  63. pmc Sex differences in the association of Framingham Cardiac Risk Score with cognitive decline in community-dwelling elders without clinical heart disease
    Gail A Laughlin
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Psychosom Med 73:683-9. 2011
    ....
  64. ncbi request reprint The prospective association of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-1 levels with all cause and cardiovascular disease mortality in older adults: the Rancho Bernardo Study
    Gail A Laughlin
    Department of Family and Preventive Medicine, University of California San Diego School of Medicine, La Jolla, California 92093 0607
    J Clin Endocrinol Metab 89:114-20. 2004
    ..We conclude that low baseline levels of IGF-I and IGFBP-1 increase the risk of fatal IHD among elderly men and women independent of prevalent IHD and CVD risk factors...
  65. pmc Hyperkyphotic posture and poor physical functional ability in older community-dwelling men and women: the Rancho Bernardo study
    Deborah M Kado
    Division of Geriatrics, Department of Medicine, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suite 2339, Los Angeles, CA, USA
    J Gerontol A Biol Sci Med Sci 60:633-7. 2005
    ..Our study objective was to determine the association between hyperkyphotic posture and physical functional limitations...
  66. pmc The sex-specific association of serum osteoprotegerin and receptor activator of nuclear factor kappaB legend with bone mineral density in older adults: the Rancho Bernardo study
    Anna Stern
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 0607, USA
    Eur J Endocrinol 156:555-62. 2007
    ..We examined the sex-specific associations of serum OPG, RANKL, and their ratio with bone mineral density (BMD) in older adults...
  67. pmc Kidney function and progression of coronary artery calcium in community-dwelling older adults (from the Rancho Bernardo Study)
    Simerjot Kaur Jassal
    Division of General Internal Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA
    Am J Cardiol 110:1425-33. 2012
    ..In the elderly, kidney function and CAC may not progress together...
  68. pmc Blood pressure and fasting plasma glucose rather than metabolic syndrome predict coronary artery calcium progression: the Rancho Bernardo Study
    Caroline K Kramer
    Division of Epidemiology, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Diabetes Care 32:141-6. 2009
    ..To examine the association of the metabolic syndrome, defined by World Health Organization (WHO) and Adult Treatment Panel III (ATP-III) criteria, and its components with coronary artery calcium (CAC) progression...
  69. ncbi request reprint Change in cognitive function by glucose tolerance status in older adults: a 4-year prospective study of the Rancho Bernardo study cohort
    Alka M Kanaya
    Division of General Internal Medicine, University of California, San Francisco, USA
    Arch Intern Med 164:1327-33. 2004
    ..A few studies have examined change in cognitive performance by diabetes status with disparate results. We examined the 4-year change in cognitive performance among older adults according to glucose tolerance status...
  70. pmc Plasma neutrophil gelatinase-associated lipocalin is independently associated with cardiovascular disease and mortality in community-dwelling older adults: The Rancho Bernardo Study
    Lori B Daniels
    Division of Cardiology, Department of Medicine, University of California, San Diego, La Jolla, California 92037 7411, USA
    J Am Coll Cardiol 59:1101-9. 2012
    ..The purpose of this study was to determine the association between neutrophil gelatinase-associated lipocalin (NGAL) levels and cardiovascular and all-cause mortality in community-dwelling older adults...
  71. ncbi request reprint Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II)
    Stephen Hulley
    Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, CA 94143 0560, USA
    JAMA 288:58-66. 2002
    ..The Heart and Estrogen/progestin Replacement Study (HERS) was a randomized trial of estrogen plus progestin therapy after menopause...
  72. ncbi request reprint Zinc intakes and plasma concentrations in men with osteoporosis: the Rancho Bernardo Study
    Taisun H Hyun
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0607, USA
    Am J Clin Nutr 80:715-21. 2004
    ..Low zinc intakes and reduced blood zinc concentrations have been reported to be associated with osteoporosis in women...
  73. pmc Searching for polycystic ovary syndrome in postmenopausal women: evidence of a dose-effect association with prevalent cardiovascular disease
    Andrew J Krentz
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla 92093 0607, USA
    Menopause 14:284-92. 2007
    ..To test the hypothesis that polycystic ovary syndrome (PCOS) is associated with an increased risk of atherosclerotic cardiovascular disease (CVD) in older postmenopausal women...
  74. pmc Visceral adiposity and subclinical coronary artery disease in elderly adults: Rancho Bernardo Study
    Dong Jun Kim
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, La Jolla, California, USA
    Obesity (Silver Spring) 16:853-8. 2008
    ..We examined this association in elderly, community-dwelling adults without clinically recognized CHD...
  75. pmc Vitamin d, parathyroid hormone, and cardiovascular mortality in older adults: the Rancho Bernardo study
    Simerjot K Jassal
    Division of General Internal Medicine and Geriatrics, Department of Medicine, University of California, San Diego, CA 92161, USA
    Am J Med 123:1114-20. 2010
    ..No prior studies have investigated the association between 25-hydroxyvitamin D (25[OH]D), 1,25-dihydroxyvitamin D (1,25[OH](2)D), or intact parathyroid hormone and cardiovascular mortality in a temperate climate...
  76. pmc Association of adiponectin with coronary heart disease and mortality: the Rancho Bernardo study
    Gail A Laughlin
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Am J Epidemiol 165:164-74. 2007
    ..001). These results suggest that use of adiponectin for cardiovascular disease risk stratification is premature...
  77. ncbi request reprint The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods
    Denise von Muhlen
    University of California, San Diego, United States
    Contemp Clin Trials 28:153-68. 2007
    ..Potential mechanisms of DHEA action, including the biotransformation of DHEA to active steroids and steroid metabolites, enhancement of IGF-I bioavailability, and inhibition of IL-6 production can also be evaluated...
  78. ncbi request reprint Body mass index and quality of well-being in a community of older adults
    Erik J Groessl
    Department of Family and Preventive Medicine, University of California at San Diego, San Diego, California 92093 0994, USA
    Am J Prev Med 26:126-9. 2004
    ..This study evaluates the relationship between body mass index (BMI) and HRQOL scores and gives estimates of quality-adjusted life years (QALYs) lost to overweight, obesity, and associated conditions...
  79. pmc Hormone use and lung cancer incidence: the Rancho Bernardo cohort study
    Joshua R Smith
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA
    Menopause 16:1044-8. 2009
    ..This study examines the association of hormone use and lung cancer among women...
  80. pmc Grand multiparity is associated with type 2 diabetes in Filipino American women, independent of visceral fat and adiponectin
    Maria Rosario G Araneta
    Department of Family and Preventive Medicine, University of California San Diego, San Diego, California, USA
    Diabetes Care 33:385-9. 2010
    ..To determine whether multiparity is associated with type 2 diabetes, independent of visceral adipose tissue (VAT) and adipokines...
  81. ncbi request reprint Bone mineral density in postmenopausal Caucasian, Filipina, and Hispanic women
    Deborah J Morton
    University of California, San Diego, La Jolla, CA 92093, USA
    Int J Epidemiol 32:150-6. 2003
    ..This study compared the effect of different variables representing body size on BMD in postmenopausal women aged 50-69 years from three ethnic groups in San Diego County, CA: 354 Caucasians, 285 Filipinas, and 164 Hispanics...
  82. pmc Low serum testosterone and mortality in older men
    Gail A Laughlin
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0631C, La Jolla, California 92093, USA
    J Clin Endocrinol Metab 93:68-75. 2008
    ..Declining testosterone levels in elderly men are thought to underlie many of the symptoms and diseases of aging; however, studies demonstrating associations of low testosterone with clinical outcomes are few...
  83. ncbi request reprint Type 2 diabetes and metabolic syndrome in Filipina-American women : a high-risk nonobese population
    Maria Rosario G Araneta
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, La Jolla, California 92093 0607, USA
    Diabetes Care 25:494-9. 2002
    ..To compare the prevalence of type 2 diabetes and features of the metabolic syndrome among Filipina and Caucasian women in San Diego County, California...
  84. ncbi request reprint Vitamin D, parathyroid hormone levels, and the prevalence of metabolic syndrome in community-dwelling older adults
    Jared P Reis
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
    Diabetes Care 30:1549-55. 2007
    ..We examined the association of 25(OH)D and PTH with the prevalence of metabolic syndrome in a community-based cohort of older adults...
  85. ncbi request reprint Ghrelin, adiponectin, and leptin do not predict long-term changes in weight and body mass index in older adults: longitudinal analysis of the Rancho Bernardo cohort
    Claudia Langenberg
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Am J Epidemiol 162:1189-97. 2005
    ..From this analysis of Rancho Bernardo Study data, the authors conclude that ghrelin, adiponectin, and leptin do not predict weight gain beyond reflecting the influence of attained body size on future changes in weight or body mass index...
  86. ncbi request reprint Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study
    Jee Young Oh
    Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, California 92093 0607, USA
    Diabetes Care 25:55-60. 2002
    ..To determine the prospective association between endogenous sex hormones and the development of type 2 diabetes in older men and women...
  87. pmc Measures of renal function, BMD, bone loss, and osteoporotic fracture in older adults: the Rancho Bernardo study
    Simerjot K Jassal
    Department of Medicine, University of California, San Diego, CA 92093 0607, USA
    J Bone Miner Res 22:203-10. 2007
    ..If confirmed, this may warrant adding mild to moderate renal dysfunction as an indication for osteoporosis screening...
  88. ncbi request reprint Hysterectomy status and life satisfaction in older women
    Donna Kritz-Silverstein
    Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, La Jolla, USA
    J Womens Health Gend Based Med 11:181-90. 2002
    ..This cross-sectional, population-based study examines the long-term effect of hysterectomy on life satisfaction in 1177 women aged 55-94 years...
  89. pmc Insulin-like growth factor-I and cancer mortality in older men
    Jacqueline M Major
    Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093 0631C, USA
    J Clin Endocrinol Metab 95:1054-9. 2010
    ..These results suggest caution in the use of IGF-I-enhancing therapies to slow the adverse effects of aging...
  90. pmc Estrogen therapy and bone mineral density in African-American and Caucasian women
    Susan L Eskridge
    San Diego Joint Doctoral Program in Public Health Epidemiology, San Diego State University University of California, San Diego, California, USA
    Am J Epidemiol 171:808-16. 2010
    ..13-0.37). Results suggest that higher levels of bone mineral density in African-American women were not due to estrogen use...
  91. ncbi request reprint Probable NAFLD, by ALT levels, and diabetes among Filipino-American women
    Charlene A Wong
    Division of Epidemiology and Biostatistics, Graduate School of Public Health, San Diego State University, CA, USA
    Diabetes Res Clin Pract 79:133-40. 2008
    ..Studies have shown alanine aminotransferase (ALT), a marker for non-alcoholic fatty liver disease (NAFLD), predicts type 2 diabetes (T2DM)...
  92. pmc Endothelin-1 and prevalent coronary heart disease in older men and women (the Rancho Bernardo Study)
    Alka M Kanaya
    Division of General Internal Medicine, University of California San Francisco, San Francisco, California, USA
    Am J Cardiol 99:486-90. 2007
    ..Further adjustment for ankle-brachial index and carotid intima media thickness did not alter these results. In conclusion, higher endothelin-1 levels are independently associated with CHD in women of all ages and among older men only...
  93. ncbi request reprint Sex-specific association of the androgen to oestrogen ratio with adipocytokine levels in older adults: the Rancho Bernardo Study
    Gail A Laughlin
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Clin Endocrinol (Oxf) 65:506-13. 2006
    ..We tested this hypothesis by evaluating the sex-specific, cross-sectional association of sex hormones and androgen to oestrogen ratios with serum adiponectin and leptin in older men and postmenopausal women...
  94. ncbi request reprint Association of interleukin-6 and C-reactive protein with subclinical carotid atherosclerosis (the Rancho Bernardo Study)
    Won Young Lee
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, USA
    Am J Cardiol 99:99-102. 2007
    ..The association of IL-6 was independent of CRP, but not vice versa, suggesting an effect of IL-6 on an earlier state of atherosclerosis...
  95. ncbi request reprint Predicting the development of diabetes in older adults: the derivation and validation of a prediction rule
    Alka M Kanaya
    Department of Medicine and Epidemiology and Biostatics, University of California, San Francisco, California 94115, USA
    Diabetes Care 28:404-8. 2005
    ..We created a prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort...
  96. ncbi request reprint Weight loss: a determinant of hip bone loss in older men and women. The Rancho Bernardo Study
    James D Knoke
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, San Diego, CA 92093 0607, USA
    Am J Epidemiol 158:1132-8. 2003
    ....
  97. ncbi request reprint The relationship between weight loss and all-cause mortality in older men and women with and without diabetes mellitus: the Rancho Bernardo study
    Nicole M Wedick
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093, USA
    J Am Geriatr Soc 50:1810-5. 2002
    ....
  98. pmc Clinical utility of spine bone density in elderly women
    Diane L Schneider
    Department of Medicine, University of California, San Diego, La Jolla, CA, USA
    J Clin Densitom 9:255-60. 2006
    ..In elderly women 65 yr and older who are likely to have spine OA, the DXA measurement of the spine may not be useful in assessing fracture risk, and DXA of the hip is recommended for identification of osteoporosis...
  99. ncbi request reprint Explaining the sex difference in coronary heart disease mortality among patients with type 2 diabetes mellitus: a meta-analysis
    Alka M Kanaya
    Department of Medicine, Division of General Internal Medicine, University of California, San Diego, USA
    Arch Intern Med 162:1737-45. 2002
    ..Most studies suggest that diabetes is a stronger coronary heart disease (CHD) risk factor for women than men, but few have adjusted their results for classic CHD risk factors: age, hypertension, total cholesterol level, and smoking...
  100. ncbi request reprint Cardiovascular death and the metabolic syndrome: role of adiposity-signaling hormones and inflammatory markers
    Claudia Langenberg
    Department of Family and Preventive Medicine, School of Medicine, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0607, USA
    Diabetes Care 29:1363-9. 2006
    ..Levels of adiposity-signaling hormones and inflammatory markers are less favorable in individuals with the metabolic syndrome; their role in the association between the metabolic syndrome and cardiovascular mortality remains unclear...
  101. pmc A prospective study of abdominal obesity and coronary artery calcium progression in older adults
    Caroline K Kramer
    Department of Family and Preventive Medicine, University of California, La Jolla, California 92093 0631, USA
    J Clin Endocrinol Metab 94:5039-44. 2009
    ..Little is known about obesity measurements and coronary artery calcium (CAC) progression in older adults. We examined the sex-specific association between measures of body size and fat distribution with CAC progression...

Research Grants22

  1. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 1999
    ....
  2. CVD Predictors of Cognitive Function Trajectory over 20 Years
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ..This information is important given the aging of the population, the fact that CVD risk factors are modifiable, and because the maintenance of cognitive function is an essential component of healthy aging. ..
  3. Osteoporotic Fractures in Men - MrOS Renewal
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ....
  4. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
  5. Gender differences in Bone Loss and Incident Fractures
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ..abstract_text> ..
  6. CVD Predictors of Cognitive Function Trajectory over 20 Years
    Elizabeth Barrett Connor; Fiscal Year: 2009
    ..This information is important given the aging of the population, the fact that CVD risk factors are modifiable, and because the maintenance of cognitive function is an essential component of healthy aging. ..
  7. Post DPP (Diabetes Prevention Program)
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ..women, and in older subjects in the DPP. The current application is for 5 years of funding, although the some of the goals of the projects described will require a 10-year study. ..
  8. Gender differences in Bone Loss and Incident Fractures
    Elizabeth Barrett Connor; Fiscal Year: 2007
    ..Our goal is to develop a coherent picture of the interactive effects of sex hormones and lifestyle, biomarkers, vitamin D, PTH, and genes on each bone outcome. ..
  9. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2000
    ....
  10. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2001
    ....
  11. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2002
    ....
  12. GENDER DIFFERENCES IN OSTEOPOROSIS
    Elizabeth Barrett Connor; Fiscal Year: 2001
    ....
  13. Endogenous/Exogenous Sex Hormones & CHD Risk Factors
    Elizabeth Barrett Connor; Fiscal Year: 2003
    ..These observations may aid in deciding whether individual women should use HRT and, if so, which regimen would provide the most benefit with the least risk. ..
  14. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2003
    ..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
  15. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2004
    ..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
  16. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2005
    ..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
  17. Outcomes of Sleep Disorders in Older Men
    Elizabeth Barrett Connor; Fiscal Year: 2006
    ..We will also supplement the bank of MrOS specimens to allow for testing of future hypotheses concerning the role of sleep in the development of age-related diseases and conditions. ..
  18. CVD Predictors of Cognitive Function Trajectory over 20 Years
    Elizabeth L Barrett Connor; Fiscal Year: 2010
    ..This information is important given the aging of the population, the fact that CVD risk factors are modifiable, and because the maintenance of cognitive function is an essential component of healthy aging. ..