Ande Bao

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. ncbi request reprint A novel liposome radiolabeling method using 99mTc-"SNS/S" complexes: in vitro and in vivo evaluation
    Ande Bao
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    J Pharm Sci 92:1893-904. 2003
  2. ncbi request reprint Setup and characterization of a human head and neck squamous cell carcinoma xenograft model in nude rats
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Otolaryngol Head Neck Surg 135:853-7. 2006
  3. ncbi request reprint Potential use of drug carried-liposomes for cancer therapy via direct intratumoral injection
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Int J Pharm 316:162-9. 2006
  4. ncbi request reprint Theoretical study of the influence of a heterogeneous activity distribution on intratumoral absorbed dose distribution
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Med Phys 32:200-8. 2005
  5. doi request reprint Intraoperative therapy with liposomal drug delivery: retention and distribution in human head and neck squamous cell carcinoma xenograft model
    Sean X Wang
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Int J Pharm 373:156-64. 2009
  6. pmc Chemoradionuclide therapy with 186Re-labeled liposomal doxorubicin in combination with radiofrequency ablation for effective treatment of head and neck cancer in a nude rat tumor xenograft model
    Anuradha Soundararajan
    Department of Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, Mail Code 7800, San Antonio, TX 78229 3900, USA
    Radiology 261:813-23. 2011
  7. pmc Combination radiofrequency ablation and intravenous radiolabeled liposomal Doxorubicin: imaging and quantification of increased drug delivery to tumors
    Hayden W Head
    Departments of Radiology, Otolaryngology, and Pathology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, MC 7800, San Antonio, TX 78229 3900, USA
    Radiology 255:405-14. 2010
  8. pmc Interventional therapy of head and neck cancer with lipid nanoparticle-carried rhenium 186 radionuclide
    J Tyler French
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MSC 7800, San Antonio, TX 78229 3900, USA
    J Vasc Interv Radiol 21:1271-9. 2010
  9. ncbi request reprint Intraoperative 186Re-liposome radionuclide therapy in a head and neck squamous cell carcinoma xenograft positive surgical margin model
    Sean X Wang
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Clin Cancer Res 14:3975-83. 2008
  10. pmc Chemoradionuclide therapy with 186re-labeled liposomal doxorubicin: toxicity, dosimetry, and therapeutic response
    Anuradha Soundararajan
    Department of Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Cancer Biother Radiopharm 26:603-14. 2011

Collaborators

Detail Information

Publications28

  1. ncbi request reprint A novel liposome radiolabeling method using 99mTc-"SNS/S" complexes: in vitro and in vivo evaluation
    Ande Bao
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    J Pharm Sci 92:1893-904. 2003
    ....
  2. ncbi request reprint Setup and characterization of a human head and neck squamous cell carcinoma xenograft model in nude rats
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Otolaryngol Head Neck Surg 135:853-7. 2006
    ..To develop and characterize a new head and neck cancer animal model...
  3. ncbi request reprint Potential use of drug carried-liposomes for cancer therapy via direct intratumoral injection
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Int J Pharm 316:162-9. 2006
    ..Higher intratumoral retention of 99mTc-liposomes accompanied by an improved intratumoral diffusion suggests that intratumorally administered liposomal drugs are potentially promising agents for solid tumor local therapy...
  4. ncbi request reprint Theoretical study of the influence of a heterogeneous activity distribution on intratumoral absorbed dose distribution
    Ande Bao
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Med Phys 32:200-8. 2005
    ..Based on these findings, the use of higher beta-energy radionuclides, such as 188Re and 90Y is more effective in delivering a higher absorbed dose to the tumor center at tumor diameters around 10 mm...
  5. doi request reprint Intraoperative therapy with liposomal drug delivery: retention and distribution in human head and neck squamous cell carcinoma xenograft model
    Sean X Wang
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Int J Pharm 373:156-64. 2009
    ..05 respectively). In conclusion, intraoperative therapy with liposome carried radionuclide drug delivery system carries great potential in treating unresectable HNSCC, and further study using therapeutic radionuclide should be explored...
  6. pmc Chemoradionuclide therapy with 186Re-labeled liposomal doxorubicin in combination with radiofrequency ablation for effective treatment of head and neck cancer in a nude rat tumor xenograft model
    Anuradha Soundararajan
    Department of Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, Mail Code 7800, San Antonio, TX 78229 3900, USA
    Radiology 261:813-23. 2011
    ....
  7. pmc Combination radiofrequency ablation and intravenous radiolabeled liposomal Doxorubicin: imaging and quantification of increased drug delivery to tumors
    Hayden W Head
    Departments of Radiology, Otolaryngology, and Pathology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, MC 7800, San Antonio, TX 78229 3900, USA
    Radiology 255:405-14. 2010
    ....
  8. pmc Interventional therapy of head and neck cancer with lipid nanoparticle-carried rhenium 186 radionuclide
    J Tyler French
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MSC 7800, San Antonio, TX 78229 3900, USA
    J Vasc Interv Radiol 21:1271-9. 2010
    ..The authors investigated the utility of liposome-carrying beta-emitting radionuclides to treat head and neck cancer by direct intratumoral infusion in nude rats...
  9. ncbi request reprint Intraoperative 186Re-liposome radionuclide therapy in a head and neck squamous cell carcinoma xenograft positive surgical margin model
    Sean X Wang
    Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Clin Cancer Res 14:3975-83. 2008
    ..The potential value of intraoperative injection of liposomal therapeutic radionuclides as a locoregional, targeted therapy in unresectable advanced HNSCC was assessed in a nude rat xenograft positive surgical margin model...
  10. pmc Chemoradionuclide therapy with 186re-labeled liposomal doxorubicin: toxicity, dosimetry, and therapeutic response
    Anuradha Soundararajan
    Department of Radiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Cancer Biother Radiopharm 26:603-14. 2011
    ..01) at 42 days postinjection. In conclusion, combination chemoradionuclide therapy with (186)Re-Doxil has promising potential, because good tumor control was achieved with limited associated toxicity...
  11. pmc Feasibility of eradication of breast cancer cells remaining in postlumpectomy cavity and draining lymph nodes following intracavitary injection of radioactive immunoliposomes
    Shihong Li
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, United States
    Mol Pharm 9:2513-22. 2012
    ....
  12. pmc Post-lumpectomy intracavitary retention and lymph node targeting of (⁹⁹m)Tc-encapsulated liposomes in nude rats with breast cancer xenograft
    Shihong Li
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229 3900, USA
    Breast Cancer Res Treat 130:97-107. 2011
    ....
  13. pmc [(186)Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model
    Anuradha Soundararajan
    Department of Radiology, University of Texas Health Science Center, San Antonio, 78229 3900, USA
    Nucl Med Biol 36:515-24. 2009
    ..These results suggest that the long circulation and prolonged bioavailability of [(186)Re]Doxil could potentially deliver high concentrations of both doxorubicin and (186)Re to tumor when encapsulated in the same liposome vehicle...
  14. ncbi request reprint 186Re-liposome labeling using 186Re-SNS/S complexes: in vitro stability, imaging, and biodistribution in rats
    Ande Bao
    Department of Radiology, University of Texas Health Science Center at San Antonio, 78229, USA
    J Nucl Med 44:1992-9. 2003
    ..The purpose of this study was to develop a practical method for labeling liposomes with therapeutic rhenium radionuclides, using (186)Re as an example...
  15. pmc Direct intratumoral infusion of liposome encapsulated rhenium radionuclides for cancer therapy: effects of nonuniform intratumoral dose distribution
    Brian A Hrycushko
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    Med Phys 38:1339-47. 2011
    ....
  16. pmc Radiobiological characterization of post-lumpectomy focal brachytherapy with lipid nanoparticle-carried radionuclides
    Brian A Hrycushko
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Phys Med Biol 56:703-19. 2011
    ..046%) of the healthy ipsilateral breast. Modeling of kidney BED and ipsilateral breast NTCP showed that large injected activity concentrations of both radionuclides could be safely administered without significant complications...
  17. doi request reprint Real-time iterative monitoring of radiofrequency ablation tumor therapy with 15O-water PET imaging
    Ande Bao
    Department of Radiology, University of Texas Health Science Center, San Antonio, Texas, USA
    J Nucl Med 49:1723-9. 2008
    ..In this study, (15)O-water PET was evaluated as a tool to provide real-time feedback and iterative image guidance to rapidly monitor the intratumoral coverage of radiofrequency (RF) ablation therapy...
  18. pmc Rhenium-186 liposomes as convection-enhanced nanoparticle brachytherapy for treatment of glioblastoma
    William T Phillips
    Department of Radiology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Neuro Oncol 14:416-25. 2012
    ..Analysis of tumors by histology revealed minimal areas of necrosis and gliosis. These results support the potential efficacy of the highly specific activity of brachytherapy by (186)Re-liposomes convection-enhanced delivery in glioma...
  19. pmc Postlumpectomy focal brachytherapy for simultaneous treatment of surgical cavity and draining lymph nodes
    Brian A Hrycushko
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Int J Radiat Oncol Biol Phys 79:948-55. 2011
    ....
  20. doi request reprint Imaging of 186Re-liposome therapy in ovarian cancer xenograft model of peritoneal carcinomatosis
    Cristina L Zavaleta
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Drug Target 16:626-37. 2008
    ..Omental fat in control rats had numerous tumor cells compared with treated rats. Results show the potential for (186)Re-blue-biotin-liposome/avidin system in treating advanced ovarian cancer involving peritoneal carcinomatosis...
  21. doi request reprint Remote-loading labeling of liposomes with (99m)Tc-BMEDA and its stability evaluation: effects of lipid formulation and pH/chemical gradient
    Shihong Li
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    J Liposome Res 21:17-27. 2011
    ..These in vitro characterization results have indicated the optimism of using (99m)Tc-BMEDA for labeling pH/GSH gradient liposomes without the requirement of modifying lipid formulation for liposomal therapeutic-agent development...
  22. pmc Improved tumour response prediction with equivalent uniform dose in pre-clinical study using direct intratumoural infusion of liposome-encapsulated ¹⁸⁶Re radionuclides
    Brian A Hrycushko
    Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Phys Med Biol 56:5721-34. 2011
    ..The improved predictability achieved when using EUD calculations for this cancer therapy modality may be useful for treatment planning and evaluation...
  23. doi request reprint Techniques for loading technetium-99m and rhenium-186/188 radionuclides into pre-formed liposomes for diagnostic imaging and radionuclide therapy
    Beth Goins
    Department of Radiology, University of Texas Health Science Center, San Antonio, USA
    Methods Mol Biol 606:469-91. 2010
    ....
  24. ncbi request reprint Direct 99mTc labeling of pegylated liposomal doxorubicin (Doxil) for pharmacokinetic and non-invasive imaging studies
    Ande Bao
    Department of Radiology, University of Texas Health Science Center at San Antonio, 78229 3900, USA
    J Pharmacol Exp Ther 308:419-25. 2004
    ..This labeling method may be extended to (186)Re and (188)Re labeling to combine chemotherapy and radionuclide therapy for tumor treatment...
  25. doi request reprint Radioactive liposomes
    William Thomas Phillips
    Radiology Department, University of Texas Health Science Center at San Antonio, TX, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:69-83. 2009
    ..Many of the radiolabeling and tracking technologies developed for nanosized liposomes will also be useful for the imaging and tracking of other nanoparticles...
  26. pmc Novel asparagine-derived lipid enhances distearoylphosphatidylcholine bilayer resistance to acidic conditions
    Adelphe M Mfuh
    Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249 1644, USA
    Langmuir 27:4447-55. 2011
    ....
  27. pmc Novel multifunctional theranostic liposome drug delivery system: construction, characterization, and multimodality MR, near-infrared fluorescent, and nuclear imaging
    Shihong Li
    Department of Radiology and Department of Otolaryngology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, San Antonio, Texas
    Bioconjug Chem 23:1322-32. 2012
    ....
  28. ncbi request reprint Spatial dose distributions in solid tumors from 186Re transported by liposomes using HS radiochromic media
    Luis A Medina
    Instituto de Fisica, UNAM, A P 20 364, Mexico 01000 D F, Mexico
    Eur J Nucl Med Mol Imaging 34:1039-49. 2007
    ..A procedure for the measurement of spatial dose rate distribution of beta particles emitted by 186Re-liposomes in tumoral tissue, using HS GafChromic films, is presented...

Research Grants3

  1. Image-Guided Interventional Cancer Therapy with Liposomal Radionuclides
    Ande Bao; Fiscal Year: 2009
    ..This method will potentially benefit cancer patients by enhancing tumor drug concentrations and thereby improving tumor therapy while decreasing damage to normal tissue. ..
  2. Image-Guided Interventional Cancer Therapy with Liposomal Radionuclides
    Ande Bao; Fiscal Year: 2010
    ..This method will potentially benefit cancer patients by enhancing tumor drug concentrations and thereby improving tumor therapy while decreasing damage to normal tissue. ..