Research Topics
Species | Ajay BansalSummaryAffiliation: University of Kansas Medical Center Country: USA Publications
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Detail Information
Publications
Discovery and validation of Barrett's esophagus microRNA transcriptome by next generation sequencingAjay Bansal
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Kansas, United States of America
PLoS ONE 8:e54240. 2013..Barrett's esophagus (BE) is transition from squamous to columnar mucosa as a result of gastroesophageal reflux disease (GERD). The role of microRNA during this transition has not been systematically studied...
Correlation of epidermal growth factor receptor with morphological features of colorectal advanced adenomas: a pilot correlative case seriesAjay Bansal
Department of Gastroenterology, Veterans Affairs Medical Center, Kansas City, MO, USA
Am J Med Sci 340:296-300. 2010..Although EGFR is described to be overexpressed in adenomas, to the authors' knowledge, its relationship with advanced features in adenomas and as a marker for adenoma progression has not been studied...- Feasibility of mcroRNAs as biomarkers for Barrett's Esophagus progression: a pilot cross-sectional, phase 2 biomarker studyAjay Bansal
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center and University of Kansas Medical Center, Kansas City, Kansas, USA
Am J Gastroenterol 106:1055-63. 2011..Risk stratification of Barrett's esophagus (BE) using biomarkers remains an important goal. We evaluated feasibility and clinical accuracy of novel microRNA (miRNA) biomarkers for prediction of BE dysplasia... - Impact of measurement of esophageal acid exposure close to the gastroesophageal junction on diagnostic accuracy and event-symptom correlation: a prospective study using wireless dual pH monitoringAjay Bansal
Divisions of Gastroenterology and Hepatology, University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Am J Gastroenterol 104:2918-25. 2009.... - Risk factors for progression of low-grade dysplasia in patients with Barrett's esophagusSachin Wani
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri 64128 2295, USA
Gastroenterology 141:1179-86, 1186.e1. 2011..We assessed the effects of consensus diagnosis of LGD on progression rates to HGD and EAC among expert pathologists... - Prevalence and predictors of columnar lined esophagus in gastroesophageal reflux disease (GERD) patients undergoing upper endoscopyGokulakrishnan Balasubramanian
Department of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Am J Gastroenterol 107:1655-61. 2012..The objective of this study was to prospectively evaluate the prevalence and risk factors of CLE in a large cohort of GERD patients undergoing upper endoscopy... 
A feasibility trial of narrow band imaging endoscopy in patients with gastroesophageal reflux diseasePrateek Sharma
Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, Kansas City, Missouri 64128 2295, USA
Gastroenterology 133:454-64; quiz 674. 2007..Narrow band imaging (NBI) endoscopy system enhances visualization of microvasculature and mucosal patterns. This study assessed the utility of NBI in patients with gastroesophageal reflux disease (GERD) symptoms...- Adequacy of esophageal squamous mucosa specimens obtained during endoscopy: are standard biopsies sufficient for postablation surveillance in Barrett's esophagus?Neil Gupta
Department of Gastroenterology, Veterans Affairs Medical Center, Kansas City, MO, USA
Gastrointest Endosc 75:11-8. 2012..After endoscopic eradication therapy (EET) for Barrett's esophagus (BE), surveillance of residual/recurrent intestinal metaplasia/dysplasia including subsquamous tissue is performed by using biopsy forceps... - Novel probe-based confocal laser endomicroscopy criteria and interobserver agreement for the detection of dysplasia in Barrett's esophagusSrinivas Gaddam
Department of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Am J Gastroenterol 106:1961-9. 2011..The objectives of this study were to create and test novel pCLE criteria for dysplastic BE (phase I), and to evaluate accuracy, interobserver variability, and learning curve in dysplasia prediction (phase II) using these criteria... - Longer inspection time is associated with increased detection of high-grade dysplasia and esophageal adenocarcinoma in Barrett's esophagusNeil Gupta
Division of Gastroenterology, Kansas City Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gastrointest Endosc 76:531-8. 2012..Current guidelines recommend that endoscopic surveillance of Barrett's esophagus (BE) be performed by using a strict biopsy protocol. However, novel methods to improve BE surveillance are still needed... - Prevalence of advanced histological features in diminutive and small colon polypsNeil Gupta
Division of Gastroenterology, Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, USA
Gastrointest Endosc 75:1022-30. 2012..Advanced histological features such as villous histology, high-grade dysplasia, and/or cancer in these polyps could deter adoption of these strategies... - Randomized, controlled trial of standard-definition white-light, high-definition white-light, and narrow-band imaging colonoscopy for the detection of colon polyps and prediction of polyp histologyAmit Rastogi
University of Kansas School of Medicine, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gastrointest Endosc 74:593-602. 2011..Missing adenomas and the inability to accurately differentiate between polyp histology remain the main limitations of standard-definition white-light (SD-WL) colonoscopy... - High accuracy of narrow band imaging without magnification for the real-time characterization of polyp histology and its comparison with high-definition white light colonoscopy: a prospective studyAmit Rastogi
Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Am J Gastroenterol 104:2422-30. 2009..hyperplastic) by evaluating the surface mucosal and vascular patterns... - Standard endoscopy with random biopsies versus narrow band imaging targeted biopsies in Barrett's oesophagus: a prospective, international, randomised controlled trialPrateek Sharma
Division of Gastroenterology, Department of Veterans Affairs Medical Center, 4801 E Linwood Blvd, Kansas City, MO 64128, USA
Gut 62:15-21. 2013..Narrow band imaging (NBI) highlights surface patterns that correlate with IM and neoplasia in BO... - Higher adenoma detection rates with cap-assisted colonoscopy: a randomised controlled trialAmit Rastogi
Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gut 61:402-8. 2012..The aim of this study was to compare CAC with standard colonoscopy (SC; high-definition white light) for adenoma detection rates... - Endoscopy for upper GI cancer screening in the general population: a cost-utility analysisNeil Gupta
Division of Gastroenterology, University of Kansas School of Medicine, Kansas City, Kansas, USA
Gastrointest Endosc 74:610-624.e2. 2011.... - Risk factors for nocturnal reflux in a large GERD cohortSrinivas Gaddam
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, MO 64128 2295, USA
J Clin Gastroenterol 45:764-8. 2011..However, there is limited information on independent predictors of nocturnal GERD... - Greater interobserver agreement by endoscopic mucosal resection than biopsy samples in Barrett's dysplasiaSachin Wani
Division of Gastroenterology and Hepatology and Department of Pathology, Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri 64128 2295, USA
Clin Gastroenterol Hepatol 8:783-8. 2010..We analyzed the histopathologic characteristics of specimens collected during EMR compared with biopsy specimens from patients with BE and assessed interobserver variability in pathologists' assessment of EMR and biopsy specimens... - A comparative study of endoscopic ultrasound guided fine needle aspiration with and without a styletSachin Wani
Division of Gastroenterology and Hepatology, Department of Pathology, Veterans Affairs Medical Center, University of Kansas School of Medicine, 4801 E Linwood Blvd, Kansas City, MO 64128 2295, USA
Dig Dis Sci 56:2409-14. 2011..Despite lack of evidence, use of a stylet during endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is assumed to improve the quality and diagnostic yield of specimens... - Recognition of surface mucosal and vascular patterns of colon polyps by using narrow-band imaging: interobserver and intraobserver agreement and prediction of polyp histologyAmit Rastogi
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Gastrointest Endosc 69:716-22. 2009..Earlier we described, in a pilot study, patterns seen on the polyp surface with NBI that can help differentiate between adenomas and hyperplastic polyps with a high degree of accuracy... - The diagnostic accuracy of esophageal capsule endoscopy in patients with gastroesophageal reflux disease and Barrett's esophagus: a blinded, prospective studyPrateek Sharma
Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Am J Gastroenterol 103:525-32. 2008..Esophageal capsule endoscopy (ECE) is a novel technique that offers noninvasive evaluation of esophageal pathology in gastroesophageal reflux disease (GERD) patients... - Narrow-band imaging colonoscopy--a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosisAmit Rastogi
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, Kansas City, Missouri 64128, USA
Gastrointest Endosc 67:280-6. 2008..Narrow-band imaging (NBI) is a novel technology that enhances the visualization of surface mucosal and vascular patterns... - Clinical utility and interobserver agreement of autofluorescence imaging and magnification narrow-band imaging for the evaluation of Barrett's esophagus: a prospective tandem studyMaria Giacchino
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri
Gastrointest Endosc 77:711-8. 2013..New endoscopic imaging techniques, such as autofluorescence imaging (AFI) and narrow-band imaging (NBI), have been developed to improve the detection of neoplastic lesions in Barrett's esophagus (BE)... - Accuracy of in vivo optical diagnosis of colon polyp histology by narrow-band imaging in predicting colonoscopy surveillance intervalsNeil Gupta
Division of Gastroenterology, Kansas City Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Gastrointest Endosc 75:494-502. 2012..Narrow-band imaging (NBI) has been shown to predict polyp histology with moderate to high accuracy in several studies... - Validation of the Prague C & M criteria for the endoscopic grading of Barrett's esophagus by gastroenterology trainees: a multicenter studyBabac Vahabzadeh
Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gastrointest Endosc 75:236-41. 2012..Its performance among gastroenterology trainees is unknown... - Patients with nondysplastic Barrett's esophagus have low risks for developing dysplasia or esophageal adenocarcinomaSachin Wani
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri, USA
Clin Gastroenterol Hepatol 9:220-7; quiz e26. 2011..We studied the incidences of dysplasia and EAC and investigated factors associated with progression of BE... - Esophageal adenocarcinoma in Barrett's esophagus after endoscopic ablative therapy: a meta-analysis and systematic reviewSachin Wani
Division of Gastroenterology and Hepatology, Veterans Affairs Medical Center, University of Kansas School of Medicine, Kansas City, Missouri, USA
Am J Gastroenterol 104:502-13. 2009..The objective of this study was to determine the cancer incidence in BE patients after ablative therapy and compare these rates to cohort studies of BE patients not undergoing ablation... - Screening and surveillance of Barrett's esophagusJeff Michalak
University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, MO 64128, USA
Curr Gastroenterol Rep 11:195-201. 2009..Future application of molecular biomarkers may help identify the patients with BE most likely to progress, and the use of novel imaging methods may improve outcomes of BE screening and surveillance... - Predictors of progression in Barrett's esophagus: current knowledge and future directionsGanapathy A Prasad
Division of Gastroenterology and Hepatology, Barrett s Esophagus Unit, Mayo Clinic, Rochester, MN 55905, USA
Am J Gastroenterol 105:1490-1502. 2010..Although it would be challenging, creation of such a score has the potential to improve outcomes and make the management of patients with BE more cost-effective... - Real-time increased detection of neoplastic tissue in Barrett's esophagus with probe-based confocal laser endomicroscopy: final results of an international multicenter, prospective, randomized, controlled trialPrateek Sharma
Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri, USA
Gastrointest Endosc 74:465-72. 2011..Probe-based confocal laser endomicroscopy (pCLE) allows real-time detection of neoplastic Barrett's esophagus (BE) tissue. However, the accuracy of pCLE in real time has not yet been extensively evaluated... - Correlation between narrow band imaging and nonneoplastic gastric pathology: a pilot feasibility trialAjay Bansal
Department of Gastroenterology and Pathology, University of Kansas School of Medicine, Kansas City, Missouri, USA
Gastrointest Endosc 67:210-6. 2008..A novel narrow band imaging (NBI) system is able to visualize the mucosal and vascular network in the GI tract... - Incidence of esophageal adenocarcinoma in patients with Barrett's esophagus and high-grade dysplasia: a meta-analysisAmit Rastogi
Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, Kansas City, MO 64128, USA
Gastrointest Endosc 67:394-8. 2008..However, the reported rate of cancer development in patients with HGD who were undergoing surveillance has varied among published studies... - Weight loss can lead to resolution of gastroesophageal reflux disease symptoms: A prospective intervention trialMandeep Singh
Department of Gastroenterology, Veterans Affairs Medical Center, Kansas City, Missouri, USA Department of Gastroenterology, University of Kansas Medical Center, Kansas City, Kansas, USA
Obesity (Silver Spring) 21:284-90. 2013..05). Conclusions: In conclusion, the overall prevalence of GERD symptoms is high (37%) in overweight and obese subjects. A structured weight loss program can lead to complete resolution of GERD symptoms in the majority of these subjects... - A prospective, single-blind, randomized, controlled trial of EUS-guided FNA with and without a styletAmit Rastogi
Veterans Affairs Medical Center, Kansas City, KS, USA
Gastrointest Endosc 74:58-64. 2011..Reinserting the stylet into the needle after every pass is tedious and time-consuming, and there are no data to suggest that it improves the quality of the cytology specimen... - Treatment of GERD complications (Barrett's, peptic stricture) and extra-oesophageal syndromesAjay Bansal
Department of Medicine, Veterans Affairs Medical Center, University of Kansas, MO, USA
Best Pract Res Clin Gastroenterol 24:961-8. 2010..Treatment trials have been generally disappointing and the clinical challenge remains in accurately identifying afflicted patients who might benefit from more intensive medical or surgical reflux treatment... - Effect of proton pump inhibitor therapy on inflammatory changes in the gastric cardia (carditis)Shailender Singh
University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, Kansas, Missouri 64128, USA
Dig Dis Sci 52:2178-82. 2007..In conclusion, acid suppressive therapy with PPI did not lead to a significant reduction in carditis scores. These results suggest that GERD probably does not play a major role in the pathogenesis of inflammation in the gastric cardia... - What's new in columnar lined esophagus (Barrett's metaplasia)?Rashmi Tadiparthi
Division of Gastroenterology and Hepatology, Veteran s Affairs Medical Center and University of Kansas School of Medicine, Kansas City, Missouri 64128 2295, USA
Curr Opin Gastroenterol 24:516-20. 2008..This review endeavors to summarize the recent advances in our understanding of Barrett's esophagus with an emphasis on novel imaging techniques and endoscopic therapies... - The utility of a novel narrow band imaging endoscopy system in patients with Barrett's esophagusPrateek Sharma
Division of Gastroenterology and Hepatology, Department of Pathology, and Kansas Cancer Institute, University of Kansas School of Medicine and Veterans Affairs Medical Center, Kansas City, Missouri 64128-2295, USA
Gastrointest Endosc 64:167-75. 2006..LIMITATIONS: The open study design without a control group was the main limitation. CONCLUSIONS: NBI is a novel diagnostic tool with a high degree of accuracy for the detection of metaplastic and dysplastic tissue within the BE segment... - Has high-resolution manometry changed the approach to esophageal motility disorders?Ajay Bansal
Department of Medicine, Veterans Affairs Medical Center and University of Kansas, Kansas City, Missouri, USA
Curr Opin Gastroenterol 26:344-51. 2010..The purpose of the current review is to discuss the salient advantages of HRM that are likely to change the clinical practice of manometry...