Research Topics
Species | David R BangsbergSummaryAffiliation: University of California Country: USA Publications
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Publications
Provider assessment of eligibility for hepatitis C treatment in HIV-infected homeless and marginally housed personsVanessa V Thompson
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, San Francisco, CA, USA
AIDS 19:S208-14. 2005..New treatments and strategies are necessary to treat this population with high rates of hepatitis C infection...- Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent populationD R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, University of California San Francisco, 94110, USA
AIDS 14:357-66. 2000..To examine the relationship between adherence, viral suppression and antiretroviral resistance in HIV-infected homeless and marginally housed people on protease inhibitor (PI) therapy... - Adherence-resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitnessDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, UCSF, San Francisco, California 94143 1372, USA
AIDS 20:223-31. 2006.... - Monitoring adherence to HIV antiretroviral therapy in routine clinical practice: The past, the present, and the futureDavid R Bangsberg
University of California, San Francisco, California, USA
AIDS Behav 10:249-51. 2006 - Less than 95% adherence to nonnucleoside reverse-transcriptase inhibitor therapy can lead to viral suppressionDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, and the Positive Health Program, San Francisco General Hospital, University of California, San Francisco, CA 94143 1372, USA
Clin Infect Dis 43:939-41. 2006..Although perfect adherence is an important goal, viral suppression is possible with moderate adherence to potent regimens... - Paradoxes of adherence and drug resistance to HIV antiretroviral therapyDavid R Bangsberg
The Epidemiology and Prevention Interventions Center, San Francisco General Hospital, UCSF, CA 94110, USA
J Antimicrob Chemother 53:696-9. 2004..These dynamic relationships should be considered in balancing the individual and public health benefits of therapy... - Adherence-resistance relationships to combination HIV antiretroviral therapyDavid R Bangsberg
San Francisco General Hospital, UCSF, 1001 Potrero Avenue, Building 100, Room 301, San Francisco, CA 94110, USA
Curr HIV/AIDS Rep 4:65-72. 2007..Optimal antiretroviral regimens should be constructed such that there is little overlap in the window of adherence that selects for antiretroviral drug resistance... - Modeling the HIV protease inhibitor adherence-resistance curve by use of empirically derived estimatesDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital AIDS Program, University of California San Francisco, 94110, USA
J Infect Dis 190:162-5. 2004..Higher levels of viral suppression at 100% adherence (a marker of greater regimen potency) progressively reduce the overall population rate of drug resistance and shift the peak resistance rate to lower levels of adherence... - Computer-assisted self-interviewing (CASI) to improve provider assessment of adherence in routine clinical practiceDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, University of California San Francisco, 94110, USA
J Acquir Immune Defic Syndr 31:S107-11. 2002..Computer-assisted self-interview technology is an efficient means to identify HIV antiretroviral regimen errors and monitor adherence in order to maximize the benefits of therapy... 
A paradigm shift to prevent HIV drug resistanceDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases and Positive Health Program, San Francisco General Hospital, University of California San Francisco, California, United States of America
PLoS Med 5:e111. 2008- Clostridial myonecrosis cluster among injection drug users: a molecular epidemiology investigationDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Box 1372, Room 301, Bldg 100, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
Arch Intern Med 162:517-22. 2002..Other C perfringens isolates from patients, heroin, and the environment were determined to be polyclonal. We postulate that rapid recognition and public health notification led to rapid resolution of the outbreak... 
Preventing HIV antiretroviral resistance through better monitoring of treatment adherenceDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94143, USA
J Infect Dis 197:S272-8. 2008..Upcoming advances in adherence monitoring present opportunities to better match HIV-disease treatment strategies with individual adherence behavior...- Provider assessment of adherence to HIV antiretroviral therapyD R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases and the Positive Health Program, San Francisco General Hospital University of California, San Francisco UCSF 94110, USA
J Acquir Immune Defic Syndr 26:435-42. 2001..Adherence assessment is an essential component of monitoring HIV antiretroviral therapy. Prior studies suggest that medical providers frequently estimate individual patient adherence inaccurately... - Food insecurity is associated with morbidity and patterns of healthcare utilization among HIV-infected individuals in a resource-poor settingSheri D Weiser
Division of HIV AIDS, San Francisco General Hospital, University of California, San Francisco, 94143, USA
AIDS 26:67-75. 2012..We undertook a longitudinal study in rural Uganda to understand the association of food insecurity with morbidity and patterns of healthcare utilization among HIV-infected individuals enrolled in an antiretroviral therapy program... - Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San FranciscoSheri D Weiser
Positive Health Program, San Francisco General Hospital, UCSF, San Francisco, CA 94143 1372, USA
J Gen Intern Med 24:14-20. 2009..We hypothesized that food insecurity would be associated with poor virologic response among homeless and marginally housed HIV-positive ARV-treated patients... - High levels of adherence do not prevent accumulation of HIV drug resistance mutationsDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, California, USA
AIDS 17:1925-32. 2003..Exceptionally high levels of adherence will not prevent population levels of drug resistance... - Social, structural and behavioral determinants of overall health status in a cohort of homeless and unstably housed HIV-infected menElise D Riley
Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 7:e35207. 2012..We empirically ranked factors that longitudinally impact the overall health status of HIV-infected homeless and unstably housed men... - Conceptual framework for understanding the bidirectional links between food insecurity and HIV/AIDSSheri D Weiser
Division of HIV AIDS, San Francisco General Hospital, USA
Am J Clin Nutr 94:1729S-1739S. 2011..More research on the relative importance of each of these pathways is warranted because effective interventions to reduce food insecurity and HIV depend on a rigorous understanding of these multifaceted relationships... - Brief report: Factors associated with depression among homeless and marginally housed HIV-infected men in San FranciscoSheri D Weiser
Center for AIDS Prevention Studies, University of California, San Francisco, CA, USA
J Gen Intern Med 21:61-4. 2006..To evaluate the prevalence of and factors associated with depression among HIV-infected homeless and marginally housed men... - Food insecurity among homeless and marginally housed individuals living with HIV/AIDS in San FranciscoSheri D Weiser
University of California San Francisco, San Francisco, CA 94143, USA
AIDS Behav 13:841-8. 2009..Screening for and addressing food insecurity should be a critical component of HIV prevention and treatment programs... - Revolving doors: imprisonment among the homeless and marginally housed populationMargot B Kushel
Division of General Internal Medicine, University of California San Francisco at SF General Hospital, San Francisco, CA 94143, USA
Am J Public Health 95:1747-52. 2005..We studied a sample of homeless and marginally housed adults to examine whether a history of imprisonment was associated with differences in health status, drug use, and sexual behaviors among the homeless... - The independent effect of drug resistance on T cell activation in HIV infectionPeter W Hunt
Positive Health Program, San Francisco General Hospital, University of California, San Francisco, California 94110, USA
AIDS 20:691-9. 2006.... - Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: a prospective studyAndrew R Moss
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110, USA
Clin Infect Dis 39:1190-8. 2004.... - A causal framework for understanding the effect of losses to follow-up on epidemiologic analyses in clinic-based cohorts: the case of HIV-infected patients on antiretroviral therapy in AfricaElvin H Geng
Division of HIV AIDS and Infectious Diseases, San Francisco General Hospital, Department of Medicine, School of Medicine, University of California, San Francisco, 995 Potrero Avenue, Building 80, Box 0874, San Francisco, CA 94110, USA
Am J Epidemiol 175:1080-7. 2012..A sampling-based approach can in general strengthen epidemiologic analyses conducted in many clinic-based cohorts, including those examining other diseases... - Higher rates of viral suppression with nonnucleoside reverse transcriptase inhibitors compared to single protease inhibitors are not explained by better adherenceSheri D Weiser
Center for AIDS Prevention Studies, University of California San Francisco UCSF, San Francisco, CA 94143, USA
HIV Clin Trials 5:278-87. 2004..We therefore examined adherence and viral suppression in NNRTI and single-PI regimens in a cohort of largely ARV-experienced participants by using objective measures of adherence... - Antiretroviral therapy, hepatitis C virus, and AIDS mortality among San Francisco's homeless and marginally housedElise D Riley
Epidemiology and Prevention Interventions Center, San Francisco General Hospital, University of California at San Francisco, San Francisco, CA 94110, USA
J Acquir Immune Defic Syndr 38:191-5. 2005..HIV is the major cause of death in this population, whereas the impact of HCV infection seems to be minimal. Sustained ARV treatment significantly reduces the risk of death among the homeless... - Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in AfricaElvin H Geng
Division of HIV AIDS, Department of Medicine, San Francisco General Hospital, San Francisco, CA, USA
Trop Med Int Health 15:63-9. 2010..Losses to follow-up, however, are high in these settings and may lead to bias in understanding the determinants of mortality... - Changes in food insecurity, nutritional status, and physical health status after antiretroviral therapy initiation in rural UgandaSheri D Weiser
Department of Medicine, Division of HIV AIDS, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
J Acquir Immune Defic Syndr 61:179-86. 2012..To investigate whether time on antiretroviral therapy (ART) is associated with improvements in food security and nutritional status, and the extent to which associations are mediated by improved physical health status... - The impact of chronic hepatitis C on health-related quality of life in homeless and marginally housed individuals with HIVJudith I Tsui
San Francisco Veterans Administration Medical Center, University of California San Francisco, San Francisco, CA, 94121, USA
AIDS Behav 11:603-10. 2007..These results suggest that co-infection with HCV may have an adverse effect on HRQOL among homeless and marginally housed individuals with HIV... - Retention in care and connection to care among HIV-infected patients on antiretroviral therapy in Africa: estimation via a sampling-based approachElvin H Geng
Division of HIV AIDS at San Francisco General Hospital, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 6:e21797. 2011..Yet many lost patients may have "silently" transferred and deaths shortly after the last clinic visit more likely represent limitations in clinical care rather than access to care after initial linkage... - HIV seroconversion among the homeless and marginally housed in San Francisco: a ten-year studyJudith A Hahn
Department of Medicine, University of California, San Francisco, CA 94143-1347, USA
J Acquir Immune Defic Syndr 37:1616-9. 2004..Policy implications are that HIV resources aimed at the more stable, older homeless population should probably focus on treatment, while prevention efforts, conversely, should probably be targeted to younger homeless persons... - Directly observed antidepressant medication treatment and HIV outcomes among homeless and marginally housed HIV-positive adults: a randomized controlled trialAlexander C Tsai
Langley Porter Psychiatric Institute, University of California, San Francisco, CA, USA
Am J Public Health 103:308-15. 2013..We assessed whether directly observed fluoxetine treatment reduced depression symptom severity and improved HIV outcomes among homeless and marginally housed HIV-positive adults in San Francisco, California, from 2002 to 2008... - Cash benefits are associated with lower risk behavior among the homeless and marginally housed in San FranciscoElise D Riley
University of California, San Francisco General Hospital, Epidemiology and Prevention Interventions Center, San Francisco, California 94110, USA
J Urban Health 82:142-50. 2005..These data suggest that government subsidies are associated with positive health behaviors among the urban poor... - Tripling of methamphetamine/amphetamine use among homeless and marginally housed persons, 1996-2003Moupali Das-Douglas
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, CA 94143, USA
J Urban Health 85:239-49. 2008..Further research is needed to elucidate the most effective prevention and treatment for MA use and dependence among the H/M... - A simple, dynamic measure of antiretroviral therapy adherence predicts failure to maintain HIV-1 suppressionRobert Gross
Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, Center for Education and Research in Therapeutics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
J Infect Dis 194:1108-14. 2006.... - HIV seroprevalence among homeless and marginally housed adults in San FranciscoMarjorie J Robertson
Department of Epidemiology, University of California, San Francisco, USA
Am J Public Health 94:1207-17. 2004..We report HIV seroprevalence and risk factors for urban indigent adults... - The association between use of non-injection drug implements and hepatitis C virus antibody status in homeless and marginally housed persons in San FranciscoKeith A Hermanstyne
Department of Psychiatry, University of California San Francisco, 401 Parnassus Ave, Box 0984, San Francisco, CA 94143 0984, USA
J Public Health (Oxf) 34:330-9. 2012..To date research on transmission of HCV via shared implements used to snort or smoke non-injection drugs has been inconclusive... - Are untimed antiretroviral drug levels useful predictors of adherence behavior?Cheryl A Liechty
Division of Infectious Diseases, University of California San Francisco, San Francisco, CA, USA
AIDS 18:127-9. 2004..An abnormally low drug level was associated with a higher viral load. A single abnormally low untimed antiretroviral drug level can identify an individual with very low adherence at high risk of HIV disease progression and death... - Implementation of the Medicare Part D prescription drug benefit is associated with antiretroviral therapy interruptionsMoupali Das-Douglas
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, CA, 94143, USA
AIDS Behav 13:1-9. 2009..Directed interventions to monitor the long-term effects of increased cost burden on interruptions and clinical outcomes and to reduce cost burden are necessary to avoid preventable increases in morbidity and mortality... - Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adultsJayne Byakika-Tusiime
Division of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, California, United States of America
PLoS ONE 3:e3981. 2008..CONCLUSIONS/SIGNIFICANT FINDINGS: These findings provide support for the use of Triomune in resource-limited settings, although identification of the sources of intersubject variability in these populations is critical... - Trends in the clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009Elvin H Geng
Department of Medicine, San Francisco General Hospital, University of California at San Francisco, 995 Potrero Avenue, San Francisco, CA, USA
J Int AIDS Soc 14:46. 2011..Regionally representative socio-demographic, laboratory and clinical characteristics of patients accessing ART over time and across sites have not been well described... - Hepatitis C virus infection in San Francisco's HIV-infected urban poorChristopher S Hall
Division of Infectious Diseases, San Francisco General Hospital, San Francisco, California, USA
J Gen Intern Med 19:357-65. 2004..Urban poor, nonwhite individuals are less likely to receive HCV testing and subspecialty referral than their white counterparts. Antibody-negative infection may complicate screening and diagnosis in HIV-infected persons. J.. - Impact of a formulary switch from ticarcillin-clavulanate to piperacillin-tazobactam on colonization with vancomycin-resistant enterococciLisa G Winston
Department of Medicine, Division of Infectious Diseases, University of California San Francisco and SF General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Am J Infect Control 32:462-9. 2004..The prevalence of vancomycin-resistant enterococci (VRE) is increasing, despite infection control measures. Limited data link ticarcillin-clavulanate to higher VRE prevalence... - Basic subsistence needs and overall health among human immunodeficiency virus-infected homeless and unstably housed womenElise D Riley
University of California at San Francisco, UCSF Box 0874, San Francisco, CA 94143 0874, USA
Am J Epidemiol 174:515-22. 2011.... - Food insecurity as a barrier to sustained antiretroviral therapy adherence in UgandaSheri D Weiser
Division of HIV AIDS, San Francisco General Hospital, San Francisco, California, United States of America
PLoS ONE 5:e10340. 2010.... - Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapyPeter W Hunt
Department of Medicine, University of California, San Francisco, USA
AIDS 25:2123-31. 2011..To assess whether T-cell activation independently predicts the extent of CD4(+) T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy (ART)... - Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV diseaseDavid M Naeger
Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e8886. 2010..The impact of untreated and treated HIV infection on the frequency of these cells remains undefined... - Gender-specific correlates of sex trade among homeless and marginally housed individuals in San FranciscoSheri D Weiser
Epidemiology and Prevention Interventions Center, San Francisco General Hospital, San Francisco, CA 94143 1372, USA
J Urban Health 83:736-40. 2006..Our findings highlight the critical need to develop long-term services to improve housing status for homeless women, mental health services for homeless men, and drug treatment services for homeless adults involved in sex work... - Occurrence and characteristics of chronic pain in a community-based cohort of indigent adults living with HIV infectionChristine Miaskowski
Department of Physiological Nursing, University of California, San Francisco, California, USA
J Pain 12:1004-16. 2011..Participants reported pain severity similar to those with metastatic cancer. Despite high rates of substance use disorders, approximately half received prescriptions for opioid analgesics, although few for long-acting agents... - Biomarker testing to estimate under-reported heavy alcohol consumption by persons with HIV initiating ART in UgandaJudith A Hahn
University of California, San Francisco, CA 94143 0811, USA
AIDS Behav 14:1265-8. 2010..These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes... - Psychiatric correlates of HAART utilization and viral load among HIV-positive impoverished personsAdam W Carrico
University of California, San Francisco Center for AIDS Prevention Studies, California, USA
AIDS 25:1113-8. 2011..This study administered a validated screener to examine psychiatric correlates of highly active antiretroviral therapy (HAART) utilization and viral load... - The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapyMichael Rosenblum
Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 4:e7196. 2009..We hypothesized that the percent adherence to antiretroviral therapy necessary to maintain HIV suppression would decrease with longer duration of viral suppression... - The association between food insecurity and mortality among HIV-infected individuals on HAARTSheri D Weiser
Department of Medicine, Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94143 1372, USA
J Acquir Immune Defic Syndr 52:342-9. 2009..We assessed associations between food insecurity and mortality among HIV-infected antiretroviral therapy-treated individuals in Vancouver, British Columbia, and whether body max index (BMI) modified associations... - Diminishing availability of publicly funded slots for antiretroviral initiation among HIV-infected ART-eligible patients in UgandaElvin H Geng
Division of HIV AIDS, Department of Medicine, San Francisco General Hospital, San Francisco, California, USA
PLoS ONE 5:e14098. 2010..The impact of flat-line funding in the global scale up of antiretroviral therapy (ART) for HIV-infected patients in Africa has not yet been well described... - BRIEF REPORT: the aging of the homeless population: fourteen-year trends in San FranciscoJudith A Hahn
Epi Center, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA 94143 1372, USA
J Gen Intern Med 21:775-8. 2006..Homelessness is associated with high rates of health and substance use problems... - Origins of community strains of methicillin-resistant Staphylococcus aureusEdwin D Charlebois
Department of Medicine, Division of Infectious Diseases, UCSF and Clinical Laboratory, San Francisco General Hospital, San Francisco, CA 94143, USA
Clin Infect Dis 39:47-54. 2004..In a nonoutbreak setting, the hospital was the main source of community MRSA; however, the presence of genetically distinct and diverse MRSA strains indicates MRSA strains now also originate from the community... - Factors associated with seronegative chronic hepatitis C virus infection in HIV infectionGabriel Chamie
Department of Medicine, University of California, San Francisco, CA, USA
Clin Infect Dis 44:577-83. 2007..However, associated factors are not well established because of the small number of reported cases... - Understanding reasons for and outcomes of patients lost to follow-up in antiretroviral therapy programs in Africa through a sampling-based approachElvin H Geng
Division of HIV AIDS at San Francisco General Hospital, 995 Potrero Avenue, Building 80, San Francisco, CA 94110, USA
J Acquir Immune Defic Syndr 53:405-11. 2010..We sought to characterize, through a sampling-based approach, reasons for and outcomes of patients who become lost to follow-up... - Depression and drug use impact health status among marginally housed HIV-infected individualsElise D Riley
University of California, San Francisco General Hospital, Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco, California 94110, USA
AIDS Patient Care STDS 17:401-6. 2003..It appeared that depression and drug-related variables were associated with multiple dimensions of health status in this population. Interventions to treat depression and addiction may improve the health status of HIV-infected HMH... - Sexual Relationship Power and Depression among HIV-Infected Women in Rural UgandaAbigail M Hatcher
Division of HIV AIDS, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America Wits Reproductive Health and HIV Institute, University of the Witswatersrand, Johannesburg, South Africa
PLoS ONE 7:e49821. 2012..Low sexual relationship power also contributes to HIV risk, but there is limited understanding of how it relates to mental health among HIV-infected women... - Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failureJonathan Z Li
Division of Infectious Diseases, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
AIDS 26:185-92. 2012..To evaluate the risk of virologic failure conferred by suboptimal adherence to nonnucleoside reverse transcriptase inhibitors (NNRTIs) and minority NNRTI resistance mutations... - The HIV epidemic among individuals with mental illness in the United StatesSheri D Weiser
Epidemiology and Prevention Interventions Center, San Francisco General Hospital, San Francisco, CA 94143, USA
Curr HIV/AIDS Rep 1:186-92. 2004..We need to improve our design of prevention, screening, and treatment programs to better reach individuals with comorbid HIV and mental illness... - Comparison of an interferon-gamma release assay with tuberculin skin testing in HIV-infected individualsAnnie F Luetkemeyer
HIV AIDS Division, San Francisco General Hospital, University of California at San Fracisco, San Francisco, Box 0874, Building 80, 995 Potrero Avenue, San Francisco, CA 94110, USA
Am J Respir Crit Care Med 175:737-42. 2007..Although interferon (IFN)-gamma release assays are approved for the diagnosis of latent tuberculosis infection (LTBI), limited data exist regarding their performance in HIV infection... - Phosphatidylethanol (PEth) as a biomarker of alcohol consumption in HIV-positive patients in sub-Saharan AfricaJudith A Hahn
Department of Medicine, University of California, San Francisco, 94143 0886, USA
Alcohol Clin Exp Res 36:854-62. 2012..Our goal was to examine the test characteristics of a direct metabolite of alcohol consumption, phosphatidylethanol (PEth)... - Seven steps to better adherence: a practical approach to promoting adherence to antiretroviral therapyEdward L Machtinger
Division of General Internal Medicine, University of California, San Francisco, USA
AIDS Read 17:43-51. 2007..These steps can serve as a starting point or review for care providers working to support HIV-positive patients to successfully adhere to antiretroviral therapy... - Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited settingJessica H Oyugi
Epidemiology and Prevention Interventions Center and San Francisco General Hospital AIDS Program, University of California at San Francisco, San Francisco, CA 94143, USA
J Acquir Immune Defic Syndr 36:1100-2. 2004..The relative ease of administration of the 30-day visual analog scale suggests that this may be the preferred method to assess adherence in resource-poor settings... - Population-based community prevalence of methicillin-resistant Staphylococcus aureus in the urban poor of San FranciscoEdwin D Charlebois
Department of Medicine, Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, San Francisco, CA 94110, USA
Clin Infect Dis 34:425-33. 2002..Only 2 individuals (0.24%) with MRSA had no known risk factors. A total of 22 of 23 community MRSA genotypically matched clinical MRSA isolates, with 15 of 23 isolates identical to MRSA clones endemic among hospitalized patients... - Epidemiology of vancomycin-resistant Enterococcus faecium under a selective isolation policy at an urban county hospitalLisa G Winston
University of California, San Francisco/San Francisco General Hospital, 94110, USA
Am J Infect Control 30:400-6. 2002..VREF persisted in individual patients up to 46 months. CONCLUSIONS: The number of VREF infections in this facility has been low, despite appreciable colonization, for an extended period during which selective isolation was used... - Regional anthropometry changes in antiretroviral-naïve persons initiating a Zidovudine-containing regimen in Mbarara, UgandaVanessa Thompson
Department of Medicine, University of California, San Francisco, 94121, USA
AIDS Res Hum Retroviruses 27:785-91. 2011..Gains in the tricep skinfold, a reliable marker of subcutaneous fat, appeared blunted, which could indicate an inhibitory effect of zidovudine on peripheral subcutaneous fat recovery... - Internet use among Ugandan adolescents: implications for HIV interventionMichele L Ybarra
Internet Solutions for Kids, Irvine, California, United States of America
PLoS Med 3:e433. 2006..To determine the utility of developing technology-based interventions in resource-limited settings, availability and patterns of usage of the Internet first need to be assessed... - Doubts about DOT: antiretroviral therapy for resource-poor countriesCheryl A Liechty
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, Kampala, Uganda
AIDS 17:1383-7. 2003.... - High levels of subgenomic HCV plasma RNA in immunosilent infectionsFlavien Bernardin
Blood Systems Research Institute, San Francisco, CA 94118, USA
Virology 365:446-56. 2007..The absence of immunological pressure and a high viral load may therefore promote the emergence of truncated HCV subgenomic replicons in vivo... - Interactive "Video Doctor" counseling reduces drug and sexual risk behaviors among HIV-positive patients in diverse outpatient settingsPaul Gilbert
Division of Behavioral Sciences, Professionalism, and Ethics, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 3:e1988. 2008..Positive Choice, an interactive, patient-tailored computer program, was developed in the United States to improve clinic-based assessment and counseling for risky behaviors... - Routine HIV testing in Botswana: a population-based study on attitudes, practices, and human rights concernsSheri D Weiser
Physicians for Human Rights, Cambridge, Massachusetts, United States of America
PLoS Med 3:e261. 2006..The Botswana government recently implemented a policy of routine or "opt-out" HIV testing in response to the high prevalence of HIV infection, estimated at 37% of adults... - Food insufficiency is associated with high-risk sexual behavior among women in Botswana and SwazilandSheri D Weiser
Physicians for Human Rights, Cambridge, Massachusetts, USA
PLoS Med 4:1589-97; discussion 1598. 2007..We tested the hypothesis that food insufficiency is associated with HIV transmission behavior... - A population-based study on alcohol and high-risk sexual behaviors in BotswanaSheri D Weiser
Physicians for Human Rights, Cambridge, Massachusetts, United States of America
PLoS Med 3:e392. 2006..While alcohol use is strongly associated with HIV infection in Africa, few population-based studies have characterized the association of alcohol use with specific high-risk sexual behaviors... - Hepatotoxicity during nevirapine-based fixed-dose combination antiretroviral therapy in kampala, UgandaJudith A Hahn
Epidemiology and Preventions Center, Department of Medicine, San Francisco General Hospital, University of California, San Francisco
J Int Assoc Physicians AIDS Care (Chic) 6:83-6. 2007..Monitoring for NVP-related severe hepatic toxicity should be part of expanding antiretroviral treatment programs in resource-limited settings... - TGF-beta and IL-10 production by HIV-specific CD8+ T cells is regulated by CTLA-4 signaling on CD4+ T cellsMohamed Elrefaei
California Department of Public Health, Richmond, California, USA
PLoS ONE 4:e8194. 2009..Our study suggests that CTLA-4 Signaling on CD4+ T cells regulates the inhibitory functions of the HIV-specific suppressor CD8+ T cells... - Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infectionBenigno Rodriguez
Center for AIDS Research, Case Western Reserve University, Cleveland, Ohio, USA
JAMA 296:1498-506. 2006..Plasma human immunodeficiency virus (HIV) RNA level predicts HIV disease progression, but the extent to which it explains the variability in rate of CD4 cell depletion is poorly characterized... - Expanding access to HIV antiretroviral therapy among marginalized populations in the developed worldEvan Wood
AIDS 17:2419-27. 2003 - The effect of adherence on the association between depressive symptoms and mortality among HIV-infected individuals first initiating HAARTViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia, Canada
AIDS 21:1175-83. 2007..To determine the impact of depressive symptoms on mortality among HIV/AIDS patients first initiating HAART and the potential role of patient adherence as a confounder and effect modifier in this association... - Gender and the use of antiretroviral treatment in resource-constrained settings: findings from a multicenter collaborationPaula Braitstein
Department of Medicine, Indiana University, Indianapolis, Indiana, USA
J Womens Health (Larchmt) 17:47-55. 2008.... - Alcohol use, depressive symptoms and the receipt of antiretroviral therapy in southwest UgandaPriscilla Martinez
Section for International Health, Department of General Practice and Community Medicine, University of Oslo, Oslo 0407, Norway
AIDS Behav 12:605-12. 2008..Among 421 HIV-infected patients, factors associated with the receipt of ART were having at least primary education, having an opportunistic infection in the last 3 months, and not drinking within the last year... - Tuberculosis after initiation of antiretroviral therapy in low-income and high-income countriesMartin W G Brinkhof
Institute of Social and Preventive Medicine ISPM, University of Berne, Finkenhubelweg 11, CH 3012 Bern, Switzerland
Clin Infect Dis 45:1518-21. 2007..48 (95% confidence interval, 0.36-0.64) in low-income countries and 0.36 (95% confidence interval, 0.26-0.50) in high-income countries. A low CD4 cell count at the start of therapy was the most important risk factor in both settings... - Adherence is not a barrier to successful antiretroviral therapy in South AfricaCatherine Orrell
Diana, Princess of Wales HIV Research Unit, Somerset Hospital, University of Cape Town, South Africa
AIDS 17:1369-75. 2003..Speaking the same language as site staff and simplified dosing frequency were beneficial. Socio-economic status had no impact on adherence and should not be used as a limitation to ART access... - Pillbox organizers are associated with improved adherence to HIV antiretroviral therapy and viral suppression: a marginal structural model analysisMaya L Petersen
Division of Biostatistics, University of California at Berkeley School of Public Health, University of California at Berkeley, USA
Clin Infect Dis 45:908-15. 2007..Pillbox organizers are inexpensive and easily used; however, their effect on adherence to antiretroviral medications is unknown... - Profile of immunologic recovery in HIV-infected Ugandan adults after antiretroviral therapyChris A R Baker
California Department of Health Services, Richmond, California 94804, USA
AIDS Res Hum Retroviruses 23:900-5. 2007..We conclude that ART in a cohort of therapy-naive Ugandans with AIDS partially restores but does not fully reverse the immune dysfunction observed in chronic HIV infection... - Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scaleThomas P Giordano
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
HIV Clin Trials 5:74-9. 2004..Given its simplicity, the visual analogue scale adherence instrument will be useful in research and may be useful in routine patient care... - Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, UgandaJessica H Oyugi
Infectious Diseases Institute, Kampala, Uganda
AIDS 21:965-71. 2007..To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy... - 100% adherence study: educational workshops vs. video sessions to improve adherence among ART-naïve patients in Salvador, BrazilMarcia Sampaio-Sa
Federal University of Bahia, Salvador, Bahia, Brazil
AIDS Behav 12:S54-62. 2008..8% and 61.8% using ITT, respectively. No differences were found in self-reported adherence, viral load or pharmacy records between groups. We found that the educational workshop intervention does not increase adherence to ART... - Emergence of drug resistance is associated with an increased risk of death among patients first starting HAARTRobert S Hogg
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
PLoS Med 3:e356. 2006..The objective of this study was to determine the impact of the emergence of drug-resistance mutations on survival among persons initiating HAART... - How to Take HIV antiretroviral medications on time without a watch in rural UgandaMarissa Maier
PLoS Med 3:e161. 2006 - Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countriesPaula Braitstein
Lancet 367:817-24. 2006..Timely diagnosis and assessment of treatment eligibility, coupled with free provision of HAART, might reduce this excess mortality... - Examining theoretic models of adherence for validity in resource-limited settings. A heuristic approachNorma C Ware
Department of Social Medicine, Harvard University Medical School, Boston, Massachusetts 02115, USA
J Acquir Immune Defic Syndr 43:S18-22. 2006..Examples for the illustrative exercise come from preliminary qualitative research in HIV/AIDS treatment settings in Mbarara, Uganda and Jos, Nigeria... - Hepatitis C coinfection is independently associated with decreased adherence to antiretroviral therapy in a population-based HIV cohortPaula Braitstein
British Columbia Center for Excellence in HIV AIDS, University of British Columbia, Vancouver, Canada
AIDS 20:323-31. 2006..To characterize the impact of hepatitis C (HCV) serostatus on adherence to antiretroviral treatment (ART) among HIV-infected adults initiating ART... - HIV counseling and testing practices at an urban hospital in Kampala, UgandaRhoda Wanyenze
Makerere University Institute of Public Health, Kampala, Uganda
AIDS Behav 10:361-7. 2006..The findings indicate that hospitals are important venues for HIV counseling and testing... - Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countriesMartin W G Brinkhof
Institute of Social and Preventive Medicine, Bern, Switzerland
Bull World Health Organ 86:559-67. 2008..To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings... - Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levelsJean Jacques Parienti
Clinical Research and Biostatistics Department, Cote de Nacre University Hospital, Caen, France
PLoS ONE 3:e2783. 2008..We examined medication event monitoring system (MEMS) defined adherence patterns and their relation to subsequent virologic rebound... - Belief in divine healing can be a barrier to antiretroviral therapy adherence in UgandaJane Wanyama
Infectious Disease Institute, Kampala, Uganda
AIDS 21:1486-7. 2007....
Research Grants
- HIV Outcomes Research and Training in UgandaDavid Bangsberg; Fiscal Year: 2007..abstract_text> ..
- Antiretviral therapy adherence in resource poor settingDavid Bangsberg; Fiscal Year: 2003..This will be a first and necessary step to identifying the distribution and predictors of adherence to HIV antiretroviral therapy in a resource poor setting. ..
- Alcohol use and ARV treatment outcomes in UgandaDavid Bangsberg; Fiscal Year: 2004..This research will be an essential first step to determine the impact of alcohol on treatment outcomes to expanding antiretroviral therapy in sub-Saharan Africa. ..
- A RCT of HIV Adherence Case Management and Modified DOTMargot Kushel; Fiscal Year: 2007..Outcomes will be assessed quarterly during the 6-month intervention and during a 6 month post-intervention period to examine the durability of the intervention effect. ..