MICHAEL JOSEPH BAMSHAD

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis
    Mary J Emond
    Department of Biostatistics, University of Washington, Seattle, Washington, USA
    Nat Genet 44:886-9. 2012
  2. ncbi The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions
    Michael J Bamshad
    Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Am J Med Genet A 158:1523-5. 2012
  3. ncbi Sheldon-Hall syndrome
    Reha M Toydemir
    Department of Human Genetics, Howard Hughes Medical Institute, University of Utah, Salt Lake City, UT, USA
    Orphanet J Rare Dis 4:11. 2009
  4. ncbi Genetic diversity in India and the inference of Eurasian population expansion
    Jinchuan Xing
    Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA
    Genome Biol 11:R113. 2010
  5. ncbi Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Genet 9:86. 2008
  6. ncbi Exome sequencing as a tool for Mendelian disease gene discovery
    Michael J Bamshad
    Department of Pediatrics, University of Washington, Health Sciences Building RR349, 1959 NE Pacific Street, Seattle, Washington 98195 6320, USA
    Nat Rev Genet 12:745-55. 2011
  7. ncbi Race, genetics and medicine: does the color of a leopard's spots matter?
    Michael Bamshad
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98195, USA
    Curr Opin Pediatr 19:613-8. 2007
  8. ncbi Lost in translation: meaningful policies for writing about genetics and race
    Michael Bamshad
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 143:971-2. 2007
  9. ncbi Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome
    Reha M Toydemir
    Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA
    Nat Genet 38:561-5. 2006
  10. ncbi Independent evolution of bitter-taste sensitivity in humans and chimpanzees
    Stephen Wooding
    Department of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, Utah 84112 5330, USA
    Nature 440:930-4. 2006

Research Grants

  1. Genetic and Molecular Basis of Congenital Contractures
    Michael Bamshad; Fiscal Year: 2009
  2. Genetic and Molecular Basis of Congenital Contractures
    MICHAEL JOSEPH BAMSHAD; Fiscal Year: 2010

Collaborators

Detail Information

Publications18

  1. ncbi Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis
    Mary J Emond
    Department of Biostatistics, University of Washington, Seattle, Washington, USA
    Nat Genet 44:886-9. 2012
    ..aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis...
  2. ncbi The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions
    Michael J Bamshad
    Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA
    Am J Med Genet A 158:1523-5. 2012
    ..Over the next few years and in collaboration with the global human genetics community, the CMGs hope to facilitate the identification of the genes underlying a very large fraction of all Mendelian disorders; see http://mendelian.org...
  3. ncbi Sheldon-Hall syndrome
    Reha M Toydemir
    Department of Human Genetics, Howard Hughes Medical Institute, University of Utah, Salt Lake City, UT, USA
    Orphanet J Rare Dis 4:11. 2009
    ..There is no specific therapy for SHS. However, patients benefit from early intervention with occupational and physical therapy, serial casting, and/or surgery. Life expectancy and cognitive abilities are normal...
  4. ncbi Genetic diversity in India and the inference of Eurasian population expansion
    Jinchuan Xing
    Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA
    Genome Biol 11:R113. 2010
    ..Despite recent large-scale efforts in discovering human genetic variation, India's vast reservoir of genetic diversity remains largely unexplored...
  5. ncbi Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms
    W S Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
    BMC Genet 9:86. 2008
    ..An understanding of these influences is increasingly important as gene mapping and case-control studies are initiated in South Indian populations...
  6. ncbi Exome sequencing as a tool for Mendelian disease gene discovery
    Michael J Bamshad
    Department of Pediatrics, University of Washington, Health Sciences Building RR349, 1959 NE Pacific Street, Seattle, Washington 98195 6320, USA
    Nat Rev Genet 12:745-55. 2011
    ..These advances also set the stage for applying exome and whole-genome sequencing to facilitate clinical diagnosis and personalized disease-risk profiling...
  7. ncbi Race, genetics and medicine: does the color of a leopard's spots matter?
    Michael Bamshad
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98195, USA
    Curr Opin Pediatr 19:613-8. 2007
    ..The extent to which race is useful for making such predictions depends on how well race corresponds with genetic inferences of ancestry and whether ancestry is predictive of genotypes associated with risk...
  8. ncbi Lost in translation: meaningful policies for writing about genetics and race
    Michael Bamshad
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Am J Med Genet A 143:971-2. 2007
  9. ncbi Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome
    Reha M Toydemir
    Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA
    Nat Genet 38:561-5. 2006
    ..Elucidation of the genetic basis of these syndromes redefines congenital contractures as unique defects of the sarcomere and provides insights about what has heretofore been a poorly understood group of disorders...
  10. ncbi Independent evolution of bitter-taste sensitivity in humans and chimpanzees
    Stephen Wooding
    Department of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, Utah 84112 5330, USA
    Nature 440:930-4. 2006
    ..Humans and chimpanzees share variable taste sensitivity to bitter compounds mediated by PTC receptor variants, but the molecular basis of this variation has arisen twice, independently, in the two species...
  11. ncbi Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation
    Mark D Shriver
    Penn State University, University Park, Pennsylvania, USA
    Hum Genomics 2:81-9. 2005
    ....
  12. ncbi The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility
    Enrique Gonzalez
    Veterans Administration Research Center for AIDS and HIV 1 Infection, South Texas Veterans Health Care System, and Department of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA
    Science 307:1434-40. 2005
    ....
  13. ncbi Familial aggregation of juvenile idiopathic arthritis
    Sampath Prahalad
    University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Arthritis Rheum 50:4022-7. 2004
    ..To estimate the degree of familial aggregation of juvenile idiopathic arthritis (JIA), determine whether the aggregation of JIA and the aggregation of type 1 diabetes mellitus (type 1 DM) overlap, and identify multiplex JIA pedigrees...
  14. ncbi Does race exist?
    Michael J Bamshad
    University of Utah School of Medicine, USA
    Sci Am 289:78-85. 2003
  15. ncbi Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms
    W Scott Watkins
    Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA
    Genome Res 13:1607-18. 2003
    ..These analyses also demonstrate that markers with higher F(ST) values have greater resolving power and produce more consistent genetic distance estimates...
  16. ncbi Expressivity of Holt-Oram syndrome is not predicted by TBX5 genotype
    Anna-Marie E Brassington
    Department of Human Genetics, University of Utah Health Sciences Center, 15 North 2030 East, Salt Lake City, UT 84112, USA
    Am J Hum Genet 73:74-85. 2003
    ..These results suggest that neither the type of mutation in TBX5 nor the location of a mutation in the T box is predictive of the expressivity of malformations in individuals with HOS...
  17. ncbi Human population genetic structure and inference of group membership
    Michael J Bamshad
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84112, USA
    Am J Hum Genet 72:578-89. 2003
    ..This suggests that a more flexible framework is needed for making inferences about population structure and the utility of proxies...
  18. ncbi HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels
    Enrique Gonzalez
    Veterans Administration Research Center for AIDS and HIV 1 Infection and University of Texas Health Science Center, San Antonio, TX 78229, USA
    Proc Natl Acad Sci U S A 99:13795-800. 2002
    ..In a broader context, the MCP-1 -2578G allele may serve as a genetic determinant of outcome of other disease states in which MP-mediated tissue injury is central to disease pathogenesis...

Research Grants7

  1. Genetic and Molecular Basis of Congenital Contractures
    Michael Bamshad; Fiscal Year: 2009
    ..abstract_text> ..
  2. Genetic and Molecular Basis of Congenital Contractures
    MICHAEL JOSEPH BAMSHAD; Fiscal Year: 2010
    ..abstract_text> ..