Research Topics
| J M BalterSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Determination of ventilatory liver movement via radiographic evaluation of diaphragm positionJ M Balter
Department of Radiation Oncology, University of Michigan Health Systems, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 51:267-70. 2001..To determine the accuracy of estimation of liver movement inferred by observing diaphragm excursion on radiographic images...- Daily targeting of intrahepatic tumors for radiotherapyJames M Balter
Department of Radiation Oncology, University of Michigan Health Systems, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 52:266-71. 2002..This paper reports our initial experience treating 8 patients with focal liver tumors using this system... 
Quality assurance for kilo- and megavoltage in-room imaging and localization for off- and online setup error correctionJames M Balter
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 71:S48-52. 2008..The paradigms for quality assurance of radiograph-based positioning include imager performance, systems integration, infrastructure, procedure documentation and testing, and support for positioning strategy implementation...- Technical note: acquisition of CT models for radiotherapy applications with reduced tube heatingJ M Balter
Department of Radiation Oncology, University of Michigan Health Systems, Ann Arbor 48109, USA
Med Phys 28:590-2. 2001..The DRR generated via this technique is comparable to that generated with high current and 1 mm aperture, and higher resolution than from the 3 and 5 mm CT scans... - Accuracy of a wireless localization system for radiotherapyJames M Balter
Department of Radiation Oncology, University of Michigan Health System, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 61:933-7. 2005..A system has been developed for patient positioning based on real-time localization of implanted electromagnetic transponders (beacons). This study demonstrated the accuracy of the system before clinical trials... - Evaluating the influence of setup uncertainties on treatment planning for focal liver tumorsJames M Balter
Department of Radiation Oncology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 63:610-4. 2005..This study evaluates the influence of population as well as patient-specific setup distributions on treatment plans for focal liver tumors... 
Imaging opportunities in radiation oncologyJames M Balter
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 79:342-7. 2011..g., through the American College of Radiology Imaging Network (ACRIN)), and building ties through collaborative research as well as smaller joint workshops and symposia...- Advanced technologies in image-guided radiation therapyJames M Balter
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0030, USA
Semin Radiat Oncol 17:293-7. 2007..This review introduces these methods and explores their potential for initial use in guidance... - Imaging and alignment for image-guided radiation therapyJames M Balter
Department of Radiation Oncology, The University of Michigan, UH B2C432 Box 0010, 1500 East Medical Center Dr, Ann Arbor, MI 48109, USA
J Clin Oncol 25:931-7. 2007..This review explores the issues surrounding the use of imaging and image registration for treatment planning and verification, with emphasis on the underlying patient model and alignment algorithms... - Inclusion of organ deformation in dose calculationsK K Brock
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 30:290-5. 2003..8 to 7.3) Gy, respectively. The average change in the prescribed dose for the patient's actual tumor was 0.7 Gy (range 0.2 to 1.1 Gy). This patient sampling indicates the potential importance of including deformation in dose calculations... - A practical approach for quantitative estimates of voxel-by-voxel liver perfusion using DCE imaging and a compartmental modelYue Cao
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 33:3057-62. 2006..Compared to the nonlinear method, the new method can improve computational speed by a factor of approximately 400, which makes it practical for use in clinical trials... - A feasibility study of mutual information based setup error estimation for radiotherapyJ Kim
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor 48109 2122, USA
Med Phys 28:2507-17. 2001..8 degree for rotational parameters. The standard deviations of estimates from the proposed method due to detector noise were smaller than 0.3 mm and 0.07 degree for the translational parameters and rotational parameters, respectively... - Quantization of setup uncertainties in 3-D dose calculationsA E Lujan
Department of Radiation, Oncology, University of Michigan, Ann Arbor 48109, USA
Med Phys 26:2397-402. 1999..The standard deviation also yields confidence limits on the dose distribution, and these may be used to evaluate treatment plan stability... - Evaluation of multiple breathing states using a multiple instance geometry approximation (MIGA) in inverse-planned optimization for locoregional breast treatmentAlexander Lin
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 72:610-6. 2008..This study assessed whether optimization based on multiple instance geometry approximation (MIGA) could derive an IMRT plan that is less sensitive to known respiratory motions... - An application of Bayesian statistical methods to adaptive radiotherapyKwok L Lam
Department of Radiation Oncology, The University of Michigan, Ann Arbor, MI 48109, USA
Phys Med Biol 50:3849-58. 2005..We illustrate a simple procedure to apply the method in practice to adaptive radiotherapy, allowing for multiple adjustments of treatment parameters during the course of treatment... - A method for incorporating organ motion due to breathing into 3D dose calculations in the liver: sensitivity to variations in motionAnthony E Lujan
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 30:2643-9. 2003..The results point out where quality assurance efforts should be concentrated to help assure the validity of the assumptions used to correct the static dose distributions for patient breathing using the convolution method... - A method for incorporating organ motion due to breathing into 3D dose calculationsA E Lujan
Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor 48109, USA
Med Phys 26:715-20. 1999..Comparison of convolution-based calculations and direct simulation of various worst-case scenarios indicates that a single convolution-based calculation is sufficient to predict the dose distribution for the example treatment plan given... - A mathematical model for correcting patient setup errors using a tilt and roll deviceD W Litzenberg
Department of Radiation Oncology, University of Michigan, Ann Arbor 48109 0010, USA
Med Phys 26:2586-8. 1999..This design and algorithm allows complete translational and rotational corrections to be applied to the target volume position on a daily basis... - Real-time profiling of respiratory motion: baseline drift, frequency variation and fundamental pattern changeD Ruan
Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5304, USA
Phys Med Biol 54:4777-92. 2009..The proposed approach is fully unsupervised and data driven, making it ideal for applications requiring economy, efficiency and flexibility... - A comparison of ventilatory prostate movement in four treatment positionsL A Dawson
Department of Radiation Oncology University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 48:319-23. 2000..The purpose of this study is to report the influence of patient orientation and immobilization on prostate movement due to breathing... - A room-based diagnostic imaging system for measurement of patient setupJ E Schewe
Department of Radiation Oncology, University of Michigan, Ann Arbor 48109 0010, USA
Med Phys 25:2385-7. 1998..This could limit patient setup error to the uncertainty in the measurement and repositioning processes, a potentially significant improvement over the present standard... - Determination of rotations in three dimensions using two-dimensional portal image registrationA E Lujan
Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor 48109, USA
Med Phys 25:703-8. 1998..Tests using DRRs and films show that it is possible to select anatomic features in AP skull radiographs with position and orientation sensitive to out-of-plane rotation... - Inference of hysteretic respiratory tumor motion from external surrogates: a state augmentation approachD Ruan
Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI, USA
Phys Med Biol 53:2923-36. 2008..Optimization of the state augmentation is investigated. This method generalizes naturally to adaptive on-line algorithms... - Automated generation of a four-dimensional model of the liver using warping and mutual informationK M Brock
Department of Radiation Oncology, University of Michigan Health Systems, Ann Arbor, Michigan 48109, USA
Med Phys 30:1128-33. 2003.... - Intra and interfraction mediastinal nodal region motion: implications for internal target volume expansionsJonathan G Thomas
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Med Dosim 34:133-9. 2009..The degree of motion and deformation varies by station and by individual. This study indicates the potential advantage of characterizing individualized nodal region motion to safely maximize conformality of mediastinal nodal targets... - Technical note: creating a four-dimensional model of the liver using finite element analysisK K Brock
Department of Radiation Oncology, University of Michigan, Ann Arbor 48109, USA
Med Phys 29:1403-5. 2002..Intermediate states were then calculated and time weighted to determine a 4D model of the liver as it deforms during the breathing cycle. This model can be used to calculate a more accurate dose distribution during radiotherapy... - The prediction of radiation-induced liver dysfunction using a local dose and regional venous perfusion modelYue Cao
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 34:604-12. 2007..This is the first step toward developing a method to deliver higher and potentially more curative radiation doses to the patients who can safely receive these higher doses... - Short-term displacement and reproducibility of the breast and nodal targets under active breathing controlJean M Moran
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 68:541-6. 2007.... - Positional stability of electromagnetic transponders used for prostate localization and continuous, real-time trackingDale W Litzenberg
Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 68:1199-206. 2007..Ideally, the distances between transponders remains constant over the course of treatment. In this work, we evaluate the accuracy of these conditions... - A precision translation stage for reproducing measured target volume motionsDale W Litzenberg
Department of Radiation Oncology, University of Michigan Health System, Ann Arbor, Michigan, USA
J Appl Clin Med Phys 8:2221. 2007..2 mm or less, while the average typical maximum positional errors are typically 0.5 mm for an indefinite number of idealized breathing motion cycles and while reproducing measured target volume motions for several minutes... - Respiratory motion of the heart and positional reproducibility under active breathing controlReshma Jagsi
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 68:253-8. 2007..Information about cardiac motion with respiration and positional reproducibility under active breathing control (ABC) is necessary to evaluate these techniques... - Liver function after irradiation based on computed tomographic portal vein perfusion imagingYue Cao
Department of Radiation Oncology, University of Michigan, UH B2C432, Box 0010, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 70:154-60. 2008..To determine whether individual and regional liver sensitivity to radiation could be assessed by measuring liver perfusion during a course of treatment using dynamic contrast-enhanced computed tomography scanning... - Accuracy estimation for projection-to-volume targeting during rotational therapy: a feasibility studyYong Long
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109 2122, USA
Med Phys 37:2480-90. 2010..The purpose of this work is to investigate the influence of rotational arc length on maximum achievable accuracy of motion estimation... - Mean position tracking of respiratory motionDan Ruan
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 35:782-92. 2008..Estimation traces are compared with retrospectively generated moving average results to illustrate the performance of the proposed approach... - Iterative sorting for four-dimensional CT images based on internal anatomy motionRongping Zeng
Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, Michigan 48109 2122, USA
Med Phys 35:917-26. 2008..For the other two patient studies, where the external signals poorly reflected the internal motion, the proposed method significantly improved the sorted 4D CT volumes, albeit with greater computation time... - Analysis of couch position tolerance limits to detect mistakes in patient setupScott W Hadley
Department of Radiation Oncology Physics, The University of Michigan Medical School, Ann Arbor, MI, USA
J Appl Clin Med Phys 10:2864. 2009..Making better use of the software interlock on the couch positions could have a positive impact on patient safety and reduce mistakes in treatment delivery... - Influence of rotations on dose distributions in spinal stereotactic body radiotherapy (SBRT)Orit Gutfeld
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 5010, USA
Int J Radiat Oncol Biol Phys 73:1596-601. 2009..To evaluate the impact of rotational setup errors on dose distribution in spinal stereotactic body radiotherapy (SBRT)... - Objective assessment of deformable image registration in radiotherapy: a multi-institution studyRojano Kashani
Department of Radiation Oncology, University of Michigan, Ann Arbor Michigan 48109 0010, USA
Med Phys 35:5944-53. 2008..Although reasonable accuracy was achieved overall, the variation of error in different regions suggests caution in globally accepting the results from deformable alignment... - Accelerated partial breast irradiation: what is dosimetric effect of advanced technology approaches?Jean M Moran
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 75:294-301. 2009..g., free breathing [FB] and deep inspiration breath hold [DIBH])... - 3D forward and back-projection for X-ray CT using separable footprintsYong Long
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA
IEEE Trans Med Imaging 29:1839-50. 2010..The SF-TT projector is more accurate than the SF-TR projector for rays associated with large cone angles. The SF-TR projector has similar computation speed with the DD projector and the SF-TT projector is about two times slower... - Mutual information based CT registration of the lung at exhale and inhale breathing states using thin-plate splinesMartha M Coselmon
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 31:2942-8. 2004..This technique shows promise for the future development of dynamic models of the lung for use in four-dimensional (4-D) treatment planning... - Estimating 3-D respiratory motion from orbiting views by tomographic image registrationRongping Zeng
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor 48109, USA
IEEE Trans Med Imaging 26:153-63. 2007..We also present simulation and phantom results to illustrate the performance of this method... - Alterations in normal liver doses due to organ motionMihaela Rosu
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Int J Radiat Oncol Biol Phys 57:1472-9. 2003.... - A comparison of computer-controlled versus manual on-line patient setup adjustmentKristy K Brock
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0010, USA
J Appl Clin Med Phys 3:241-7. 2002..Computer controlled setup adjustment was determined to be faster (25.4 s versus 101.9 s) and slightly more accurate (1.8 mm versus 2.5 mm error in adjusted setup) than manual correction... - Evaluation of the influence of breathing on the movement and modeling of lung tumorsAaron M Allen
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Int J Radiat Oncol Biol Phys 58:1251-7. 2004..This study was designed to evaluate the influence of breathing movement on tumors and to assess the validity of the free-breathing CT scan for target delineation in the lung... - Accounting for center-of-mass target motion using convolution methods in Monte Carlo-based dose calculations of the lungIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 31:925-32. 2004..This increase is not unexpected considering that the target spends relatively more time at inhale as the asymmetry decreases (note that the treatment plans were generated using the exhale CT scans)... - Analysis of radiation-induced liver disease using the Lyman NTCP modelLaura A Dawson
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 53:810-21. 2002..To describe the dose-volume tolerance for radiation-induced liver disease (RILD) using the Lyman-Kutcher-Burman (LKB) normal tissue complication probability (NTCP) model... - Respiratory motion estimation from slowly rotating x-ray projections: theory and simulationRongping Zeng
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan 48109 2122, USA
Med Phys 32:984-91. 2005.... - Retrospective analysis of prostate cancer patients with implanted gold markers using off-line and adaptive therapy protocolsDale W Litzenberg
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 63:123-33. 2005.... - A fluence convolution method to account for respiratory motion in three-dimensional dose calculations of the liver: a Monte Carlo studyIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 30:1776-80. 2003.... - Dose reconstruction in deforming lung anatomy: dose grid size effects and clinical implicationsMihaela Rosu
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 32:2487-95. 2005.... - Influence of intrafraction motion on margins for prostate radiotherapyDale W Litzenberg
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 65:548-53. 2006..To assess the impact of intrafraction intervention on margins for prostate radiotherapy... - Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancerTwyla R Willoughby
Department of Radiation Oncology, M.D. Anderson Cancer Center Orlando, Orlando, FL 32806, USA
Int J Radiat Oncol Biol Phys 65:528-34. 2006..Clinical evaluation of this novel 4D nonionizing electromagnetic localization system with transponders indicates a comparable localization accuracy to isocenter, (within 2 mm) compared with X-ray localization... - Short-term and long-term reproducibility of lung tumor position using active breathing control (ABC)Rojano Kashani
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 65:1553-9. 2006..To evaluate the short-term and long-term reproducibility of lung tumor position for scans acquired using an active breathing control (ABC) device... - Daily prostate targeting using implanted radiopaque markersDale Litzenberg
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI 48103 0010, USA
Int J Radiat Oncol Biol Phys 52:699-703. 2002..A system has been implemented for daily localization of the prostate through radiographic localization of implanted markers. This report summarizes an initial trial to establish the accuracy of patient setup via this system... - Exploring breathing pattern irregularity with projection-based methodDan Ruan
Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor 48109, USA
Med Phys 33:2491-9. 2006..Compared to the modified cosine function, which was investigated previously for breathing pattern models, the proposed approach is more representative, flexible, and computationally efficient... - How extensive of a 4D dataset is needed to estimate cumulative dose distribution plan evaluation metrics in conformal lung therapy?Mihaela Rosu
The University of Michigan, Department of Radiation Oncology, Ann Arbor Michigan 48109 0010, USA
Med Phys 34:233-45. 2007.... - Synchronized dynamic dose reconstructionDale W Litzenberg
University of Michigan, Ann Arbor Michigan 48109, USA
Med Phys 34:91-102. 2007..These reconstructed dose fractions can then be combined to produce high-quality determinations of the dose distribution actually received to date, from which individualized adaptive treatment strategies can be determined... - The treatment planning of segmental, conformal stereotactic radiosurgery utilizing a standard multileaf collimatorP G Archer
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor 48109, USA
Med Dosim 24:13-9. 1999.... - Real-time prediction of respiratory motion based on local regression methodsD Ruan
Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI, USA
Phys Med Biol 52:7137-52. 2007..The proposed method reduced the prediction error for all imaging rates and latency lengths, particularly for long prediction lengths... - Characterization of pancreatic tumor motion using cine MRI: surrogates for tumor position should be used with cautionMary Feng
Department of Radiation Oncology, University of Michigan, USA
Int J Radiat Oncol Biol Phys 74:884-91. 2009..Our current understanding of intrafraction pancreatic tumor motion due to respiration is limited. In this study, we characterized pancreatic tumor motion and evaluated the application of several radiotherapy motion management strategies... - Effect of daily localization and correction on the setup uncertainty: dependences on the measurement uncertainty, re-positioning uncertainty and action levelKwok L Lam
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109, USA
Phys Med Biol 52:6575-87. 2007..In typical clinical situations, the distribution of the corrected setup variation can be closely approximated by a normal distribution... - Method for quantifying volumetric lesion change in interval liver CT examinationsChuck Meyer
IEEE Trans Med Imaging 22:776-81. 2003..We also quantify the accuracy of our CT liver registrations using microcoils implanted for chemotherapy. A probabilistic liver atlas is used to support automatic masking and liver-focused registration... - Interventions to reduce organ motion effects in radiation deliveryLaura A Dawson
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Ontario, Canada
Semin Radiat Oncol 14:76-80. 2004..Approaches to minimize nonrespiratory organ motion include maintaining the same preparative regimen before each treatment and ensuring comfortable immobilization and short overall treatment time... - The management of respiratory motion in radiation oncology report of AAPM Task Group 76Paul J Keall
Virginia Commonwealth University, USA
Med Phys 33:3874-900. 2006..Respiratory motion management is also appropriate when the procedure will increase normal tissue sparing. Respiratory motion management involves further resources, education and the development of and adherence to QA procedures... - ASTRO's 2007 core physics curriculum for radiation oncology residentsEric E Klein
Radiation Oncology, Washington University, St Louis, MO 63110 1093, USA
Int J Radiat Oncol Biol Phys 68:1276-88. 2007..To ensure continued commitment to a current and relevant curriculum, subject matter will be updated again in 2 years... - ASTRO's core physics curriculum for radiation oncology residentsEric E Klein
WUSM Radistion Oncology, Washington University, 4921 Parkview Place, St Louis, MO 63110 1093, USA
Int J Radiat Oncol Biol Phys 60:697-705. 2004..To ensure that the subject matter and emphasis remain current and relevant, the curriculum will be updated every 2 years...