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Species | B W BalleineSummaryAffiliation: University of California Country: USA Publications
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Publications
The role of the dorsal striatum in reward and decision-makingBernard W Balleine
Department of Psychology and the Brain Research Institute, University of California Los Angeles, Los Angeles, California 90095 1563, USA
J Neurosci 27:8161-5. 2007..We review key evidence from recent studies in rodent, nonhuman primate, and human subjects...- Parallel incentive processing: an integrated view of amygdala functionBernard W Balleine
Department of Psychology and the Brain Research Institute, University of California Los Angeles, Box 951563, Los Angeles, CA 90095 1563, USA
Trends Neurosci 29:272-9. 2006..Given that there is little if any direct behavioral evidence for the serial model, we suggest that more attention should be given to the claims of the parallel view... - The effect of lesions of the basolateral amygdala on instrumental conditioningBernard W Balleine
Department of Psychology and the Brain Research Institute, University of California Los Angeles, Los Angeles, California 90095 1563, USA
J Neurosci 23:666-75. 2003..Together these results suggest that in instrumental conditioning, the BLA mediates outcome encoding, specifically relating the sensory features of nutritive commodities to the emotional consequences induced by their consumption... - Perceptual learning enhances retrospective revaluation of conditioned flavor preferences in ratsBernard W Balleine
Department of Psychology, University of California, Los Angeles, 90095, USA
J Exp Psychol Anim Behav Process 31:341-50. 2005.... - Neural bases of food-seeking: affect, arousal and reward in corticostriatolimbic circuitsBernard W Balleine
Department of Psychology and the Brain Research Institute, University of California, Box 951563, Los Angeles, CA 90095 1563, United States
Physiol Behav 86:717-30. 2005.... - Still at the choice-point: action selection and initiation in instrumental conditioningBernard W Balleine
Department of Psychology, University of California, Los Angeles, CA, USA
Ann N Y Acad Sci 1104:147-71. 2007..We discuss a conceptual model that integrates these processes and its neural implementation... - Motivational control of blockingBernard W Balleine
Department of Psychology, University of California, Los Angeles, CA 90095 1563, USA
J Exp Psychol Anim Behav Process 32:33-43. 2006.... - The effect of lesions of the insular cortex on instrumental conditioning: evidence for a role in incentive memoryB W Balleine
Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095, USA
J Neurosci 20:8954-64. 2000.... 
The integrative function of the basal ganglia in instrumental conditioningBernard W Balleine
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, CA, United States
Behav Brain Res 199:43-52. 2009....- The role of the nucleus accumbens in instrumental conditioning: Evidence of a functional dissociation between accumbens core and shellL H Corbit
Department of Psychology, University of California Los Angeles, Los Angeles, California 90095, USA
J Neurosci 21:3251-60. 2001..This double dissociation suggests that nucleus accumbens core and shell differentially mediate the impact of instrumental and Pavlovian incentive processes, respectively, on instrumental performance... - The role of prelimbic cortex in instrumental conditioningLaura H Corbit
Department of Psychology and the Brain Research Institute, University of California, Box 951563, Los Angeles, CA 90095, USA
Behav Brain Res 146:145-57. 2003.... - Lesions of mediodorsal thalamus and anterior thalamic nuclei produce dissociable effects on instrumental conditioning in ratsLaura H Corbit
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, Los Angeles CA 90095, USA
Eur J Neurosci 18:1286-94. 2003..In contrast, far from producing a deficit, ANT lesioned rats were as sensitive to the effects of these behavioural manipulations as the sham lesioned controls... - Double dissociation of basolateral and central amygdala lesions on the general and outcome-specific forms of pavlovian-instrumental transferLaura H Corbit
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, Los Angeles, California 90095, USA
J Neurosci 25:962-70. 2005..Together, these results suggest that the BLA mediates outcome-specific incentive processes, whereas CN is involved in controlling the general motivational influence of reward-related events... - General and outcome-specific forms of Pavlovian-instrumental transfer: the effect of shifts in motivational state and inactivation of the ventral tegmental areaLaura H Corbit
Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, CA 94608, USA
Eur J Neurosci 26:3141-9. 2007.... 
Disruption of endogenous opioid activity during instrumental learning enhances habit acquisitionK M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA 90024, USA
Neuroscience 163:770-80. 2009..These data suggest that an intact endogenous opioid system is necessary for normal goal-directed learning and more importantly, reveal that a compromised endogenous opioid system during learning enhances the habitual control of actions...- The role of the hippocampus in instrumental conditioningL H Corbit
Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095, USA
J Neurosci 20:4233-9. 2000..These results suggest that, in instrumental conditioning, lesions of the dorsal hippocampus selectively impair the ability of rats to represent the causal relationship between an action and its consequences... - A specific role for posterior dorsolateral striatum in human habit learningElizabeth Tricomi
Department of Psychology, Rutgers University, Newark, NJ 07102, USA
Eur J Neurosci 29:2225-32. 2009.... - The role of the dorsomedial striatum in instrumental conditioningHenry H Yin
Department of Psychology and Brain Research Institute, University of California, Los Angeles, Box 951563, Los Angeles, CA 90095-1563, USA
Eur J Neurosci 22:513-23. 2005..Taken together, these results suggest that the posterior region of the DMS is a crucial neural substrate for the acquisition and expression of action-outcome associations in instrumental conditioning... - Blockade of NMDA receptors in the dorsomedial striatum prevents action-outcome learning in instrumental conditioningHenry H Yin
Department of Psychology and Brain Research Institute, University of California, Los Angeles, Box 951563, Los Angeles, CA 90095-1563, USA
Eur J Neurosci 22:505-12. 2005..These experiments provide the first direct evidence that, in instrumental conditioning, NMDARs in the dorsomedial striatum are involved in encoding action-outcome associations... - Distinct opioid circuits determine the palatability and the desirability of rewarding eventsK M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90024, USA
Proc Natl Acad Sci U S A 106:12512-7. 2009..Rather, changes in palatability and in the incentive value assigned to rewarding events seem to be mediated by distinct neural processes... - Consolidation and reconsolidation of incentive learning in the amygdalaSzu Han Wang
University of California, Los Angeles, USA
J Neurosci 25:830-5. 2005.... - Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6Mary Kay Lobo
Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, 695 Charles Young Drive South, Los Angeles, California 90095, USA
Nat Neurosci 10:1395-7. 2007..Thus, Gpr6 is the first striatopallidal neuron-specific genetic regulator of instrumental conditioning in a mammal... - The contribution of orbitofrontal cortex to action selectionSean B Ostlund
Department of Psychology, University of California at Los Angeles, Los Angeles, CA 90095 14563, USA
Ann N Y Acad Sci 1121:174-92. 2007..Rather than processing goal value, therefore, we hypothesize that the contribution of the OFC to goal-directed action is limited to encoding predictive stimulus-outcome relationships that can bias instrumental response selection... - Evidence of action sequence chunking in goal-directed instrumental conditioning and its dependence on the dorsomedial prefrontal cortexSean B Ostlund
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California 90095, USA
J Neurosci 29:8280-7. 2009..These findings demonstrate that rats can use sequence-level representations, or action chunks, to organize their behavior in a goal-directed manner and indicate that the dmPFC plays a critical role in this process... - Mediated conditioning versus retrospective revaluation in humans: the influence of physical and functional similarity of cuesMimi Liljeholm
Department of Psychology, UCLA, Los Angeles, CA 90095 1563, USA
Q J Exp Psychol (Hove) 62:470-82. 2009..The implications of these results for previously reported differences between humans and nonprimate animals are discussed... - Acquisition and performance of goal-directed instrumental actions depends on ERK signaling in distinct regions of dorsal striatum in ratsMichael W Shiflett
Department of Psychology, University of California, Los Angeles, Los Angeles, California 90095 1563, USA
J Neurosci 30:2951-9. 2010.... - Extracting functional equivalence from reversing contingenciesMimi Liljeholm
University of California, Los Angeles, CA 90095 1563, USA
J Exp Psychol Anim Behav Process 36:165-71. 2010..The results challenge simple associative, and attentional, accounts of acquired equivalence and favor the view that this effect is mediated by comparisons of the similarity of adjacent cue-outcome structures... - Differential involvement of the basolateral amygdala and mediodorsal thalamus in instrumental action selectionSean B Ostlund
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, Los Angeles, California 90095 1563, USA
J Neurosci 28:4398-405. 2008..These findings demonstrate that the BLA and MD make important yet distinct contributions to instrumental action selection... - Stimulus salience and retrospective revaluationMimi Liljeholm
Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
J Exp Psychol Anim Behav Process 32:481-7. 2006..In Experiment 2B, extinction of the more salient element was found to be more effective than its reinforcement in producing retrospective revaluation of the less salient element. The implications of these results are discussed... - Orbitofrontal cortex mediates outcome encoding in Pavlovian but not instrumental conditioningSean B Ostlund
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, California 90095 1563, USA
J Neurosci 27:4819-25. 2007..In contrast, OFC-lesioned rats stopped responding to both stimuli, regardless of their predictive status. Together, these findings suggest that the OFC supports outcome encoding in pavlovian, but not instrumental conditioning... - Sensitivity to instrumental contingency degradation is mediated by the entorhinal cortex and its efferents via the dorsal hippocampusLaura H Corbit
Department of Psychology University of California, Los Angeles, Los Angeles, California 90095, USA
J Neurosci 22:10976-84. 2002..The data from these tests suggest that the deficits observed previously after electrolytic hippocampal lesions were the result of damage to entorhinal efferents... - Helplessness and escape performance: glutamate-adenosine interactions in the frontal cortexAimee M Hunter
Department of Psychology, University of California, Los Angeles 90095 1563, USA
Behav Neurosci 117:123-35. 2003..These findings are consistent with the involvement of N-methyl-D-aspartate receptor activation in the frontal cortex in the helplessness effect... - Instrumental and Pavlovian incentive processes have dissociable effects on components of a heterogeneous instrumental chainLaura H Corbit
Department of Psychology, University of California, Los Angeles, Box 951563, Los Angeles, California 90095, USA
J Exp Psychol Anim Behav Process 29:99-106. 2003..Together these data suggest that Pavlovian and instrumental incentive manipulations have dissociable effects on instrumental performance... - Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learningHenry H Yin
Department of Psychology, and Brain Research Institute, University of California, Los Angeles, 1285 Franz Hall, Los Angeles, CA 90095 1563, USA
Eur J Neurosci 19:181-9. 2004..Furthermore, it suggests that, when the habit system is disrupted, control over instrumental performance reverts to the system controlling the performance of goal-directed instrumental actions... - Lesions of medial prefrontal cortex disrupt the acquisition but not the expression of goal-directed learningSean B Ostlund
Department of Psychology, The Brain Research Institute, University of California, Los Angeles, California 90095 1563, USA
J Neurosci 25:7763-70. 2005..These results indicate that the mPFC is selectively involved in the acquisition, but not the permanent storage or expression, of action-outcome associations in instrumental conditioning... - Motivational control of second-order conditioningNeil E Winterbauer
Department of Psychology, University of California, Los Angeles, 90095, USA
J Exp Psychol Anim Behav Process 31:334-40. 2005..Even when the US was irrelevant to the training motivational state, shifts in state revealed that it was encoded within the associative structure supporting 2nd-order responding... - Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioningSean B Ostlund
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California 90024, USA
J Neurosci 31:200-7. 2011..Together, the results indicate that tonic DA contributes to the control of instrumental performance by conveying information about the costs and benefits of responding to different striatal subregions... - Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food rewardKate M Wassum
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California 90024, USA
J Neurosci 31:1591-9. 2011.... - The role of Pavlovian cues in alcohol seeking in dependent and nondependent ratsSuzette V Glasner
Department of Psychiatry, Cedars Sinai Medical Center, Thalians E 142, 8730 Alden Drive, Los Angeles, California 90048, USA
J Stud Alcohol 66:53-61. 2005..The present study examined the impact of ethanol- (ETOH) associated cues on selective ETOH-seeking behavior, using a Pavlovian-instrumental transfer design in groups of alcohol-dependent and nondependent rats... - The influence of Pavlovian cues on instrumental performance is mediated by CaMKII activity in the striatumBrian J Wiltgen
Department of Psychology and the Brain Research Institute, University of California, Los Angeles, CA 90095, USA
Eur J Neurosci 25:2491-7. 2007..Therefore, the current experiments demonstrate that normal CaMKII activity in the striatum is essential for the motivational effects of reward cues on goal-directed actions... - An assessment of factors contributing to instrumental performance for sexual reward in the ratJames C Woodson
University of California Los Angeles, 90095-1563, USA
Q J Exp Psychol B 55:75-88. 2002..These data suggest that organizational steroid exposure perinatally affects the actual reward value assigned to oestrous females in adulthood, in combination with consummatory sexual experience... - Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout miceP W Frankland
Department of Neurobiology, UCLA, Los Angeles, CA 90095, USA
Mol Psychiatry 9:417-25. 2004..However, since these phenotypic changes are opposite in direction, they also suggest that murine compensatory mechanisms following loss of FMR1 function differ from those in humans... - Sexual experience interacts with steroid exposure to shape the partner preferences of ratsJames C Woodson
Department of Psychology, University of California, Los Angeles 90095 1653, USA
Horm Behav 42:148-57. 2002..These results suggest that sexual experience interacts with steroid exposure to shape partner preference... - The L-type calcium channel blocker nimodipine mitigates "learned helplessness" in ratsSamar Saade
Department of Psychology, University of California at Los Angeles, Los Angeles, CA 90095-1563, USA
Pharmacol Biochem Behav 74:269-78. 2003..Finally, administration of nimodipine at two of the three time points did improve escape responding, but only when injected immediately prior both to shock exposure and the shuttle escape test... - Calculating consequences: brain systems that encode the causal effects of actionsSaori C Tanaka
Division of the Humanities and Social Sciences and Computation and Neural Systems Program, California Institute of Technology, Pasadena, California 91125, USA
J Neurosci 28:6750-5. 2008..These results reveal the involvement of distinct brain regions in the computational processes that establish the causal efficacy of actions, providing insight into the neural mechanisms underlying the adaptive control of behavior... - Current trends in decision makingBernard W Balleine
Ann N Y Acad Sci 1104:xi-xv. 2007 - Inactivation of dorsolateral striatum enhances sensitivity to changes in the action-outcome contingency in instrumental conditioningHenry H Yin
Laboratory for Integrative Neuroscience, NIAAA NIH, 5625 Fishers Lane, Room TS 13, Rockville, MD 20852, USA
Behav Brain Res 166:189-96. 2006.... - Inhibitory sensory preconditioning detected with a sodium depletion procedureAlfredo Espinet
Facultad de Psicologia, Universidad de Malaga, Malaga, Spain
Q J Exp Psychol (Hove) 61:240-7. 2008..These results provide direct evidence of inhibition between two neutral stimuli and, therefore, of inhibitory sensory preconditioning... - Reward, motivation, and reinforcement learningPeter Dayan
Gatsby Computational Neuroscience Unit, University College London, 17 Queen Square, WC1N 3AR, London, United Kingdom
Neuron 36:285-98. 2002..We review the data and consider the involvement of a rich collection of different neural systems in various aspects of these forms of conditioning. Dopamine plays a pivotal, but complicated, role... - Instrumental learning in hyperdopaminergic miceHenry H Yin
Laboratory for Integrative Neuroscience, Section of Synaptic Pharmacology, NIAAA NIH, Bethesda, MD 20892, USA
Neurobiol Learn Mem 85:283-8. 2006..These results suggest that the elevated dopaminergic tone reduced the selectivity of stimulus control over conditioned behavior, but did not affect instrumental learning...