Research Topics
Species | Stephen T BallardSummaryAffiliation: University of South Alabama Country: USA Publications
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Publications
Liquid secretion properties of airway submucosal glandsStephen T Ballard
Department of Physiology, MSB 3074, University of South Alabama, Mobile, AL 36688, USA
J Physiol 556:1-10. 2004..The potential role of submucosal glands in cystic fibrosis lung disease is discussed...
Ionic mechanism of forskolin-induced liquid secretion by porcine bronchiStephen T Ballard
Department of Physiology, College of Medicne, University of South Alabama, Mobile, AL 36688, USA
Am J Physiol Lung Cell Mol Physiol 290:L97-104. 2006....
Restoration of mucociliary transport in the fluid-depleted trachea by surface-active instillatesStephen T Ballard
Department of Physiology, MSB 3074, University of South Alabama, Mobile, AL 36688, USA
Am J Respir Cell Mol Biol 34:500-4. 2006..We speculate that administration of surface-active substances, by aerosol or lavage, might help to restore MCT in the airways of patients with CF...
Fluid secretion by submucosal glands of the tracheobronchial airwaysStephen T Ballard
Department of Physiology, College of Medicine, University of South Alabama, Mobile, AL 36688, USA
Respir Physiol Neurobiol 159:271-7. 2007..Loss of CFTR function, which occurs in CF disease, reduces the capacity of glands to secrete fluid but not mucins. The possible links between the loss of fluid secretion capability and the complex airway pathology of CF are discussed...
Disruptive effects of anion secretion inhibitors on airway mucus morphology in isolated perfused pig lungLaura Trout
Department of Physiology, College of Medicine, University of South Alabama, Mobile AL 36688, USA
J Physiol 549:845-53. 2003....
Liquid secretion inhibitors reduce mucociliary transport in glandular airwaysStephen T Ballard
Department of Physiology, College of Medicine, University of South Alabama, Mobile, Alabama 36688, USA
Am J Physiol Lung Cell Mol Physiol 283:L329-35. 2002....
Mucociliary transport in porcine trachea: differential effects of inhibiting chloride and bicarbonate secretionJeffrey L Cooper
Department of Physiology, College of Medicine, University of South Alabama, Mobile, AL 36688, USA
Am J Physiol Lung Cell Mol Physiol 304:L184-90. 2013..4 ± 1.7 mm/min) and control group (19.5 ± 3.4 mm/min). These results indicate that ACh-stimulated MCT has greater dependence on HCO(3)(-) secretion, whereas the basal MCT rate has greater dependence on Cl(-) secretion...
Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchiChelsea J Martens
Department of Physiology, College of Medicine, University of South Alabama, Mobile, Alabama 36688, USA
Am J Physiol Lung Cell Mol Physiol 301:L236-46. 2011..0 μl·cm(-2)·h(-1)). However, CF bronchi produce mucus with twice the percent solids (~8%) of pig or non-CF human bronchi at liquid volume secretion rates ≥4.0 μl·cm(-2)·h(-1)...
Differential responses of pulmonary endothelial phenotypes to cyclical stretchJarrod B Adkison
Department of Physiology, MSB 3074, University of South Alabama, Mobile, 36688, USA
Microvasc Res 71:175-84. 2006..These data suggest that RPAEC more readily remodel cell-cell adhesions during cyclical stretch than RPMVEC and that a reduced intercellular adhesion adjacent to wounded cells could serve as transvascular leak sites in both phenotypes...
Effects of secretagogues on net and unidirectional liquid fluxes across porcine bronchial airwaysChelsea J Martens
Department of Physiology, College of Medicine, University of South Alabama, Mobile, Alabama, USA
Am J Physiol Lung Cell Mol Physiol 298:L270-6. 2010..06 +/- 0.07% and 2.15 +/- 0.07%, respectively). We conclude that this technique allows important quantitative distinctions to be made between liquid secretion and absorption in intact bronchial airways...
Naturally occurring mutations in the canine CFTR geneDomenico Spadafora
Department of Physiology, College of Medicine, University of South Alabama, Mobile, Alabama 36688, USA
Physiol Genomics 42:480-5. 2010..No substantive differences in mutation frequency were observed between the at-large, pancreatitis, and bronchiectasis dogs...
