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Genomes and GenesSpecies | Thomas BalkanySummaryAffiliation: University of Miami Country: USA Publications
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Publications
Conservation of residual acoustic hearing after cochlear implantationThomas J Balkany
Department of Otolaryngology, University of Miami Ear Institute, Miller School of Medicine, Miami, Florida 33101, USA
Otol Neurotol 27:1083-8. 2006..Surgical strategies for hearing conservation during cochlear implantation are described...
Cochlear implants in children--a reviewThomas J Balkany
Department of Otolaryngology, University of Miami Ear Institute, Florida 33101, USA
Acta Otolaryngol 122:356-62. 2002..Hearing, language and social development outcomes have been positive. We review current issues in cochlear implantation, candidacy, evaluation, surgery, habilitation, ethics and outcomes...
Modiolar proximity of three perimodiolar cochlear implant electrodesThomas J Balkany
University of Miami Ear Institute, Florida 33136, USA
Acta Otolaryngol 122:363-9. 2002..All three devices were successful in terms of locating electrode contacts very close to the modiolar wall...
Nucleus Freedom North American clinical trialThomas Balkany
University of Miami Ear Institute, Miami, FL 33101, USA
Otolaryngol Head Neck Surg 136:757-62. 2007..To evaluate hearing outcomes and effects of stimulation rate on performance with the Nucleus Freedom cochlear implant (Cochlear Americas, Denver, CO)...
The temporalis pocket technique for cochlear implantation: an anatomic and clinical studyThomas J Balkany
University of Miami Ear Institute Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
Otol Neurotol 30:903-7. 2009..Newer R/S designs feature a low profile and larger, rigid flat bottoms in which drilling a seat may be less appropriate. We report a technique for securing the R/S without drilling bone...
Tympanomeatal flapsThomas J Balkany
Department of Otolaryngology, University of Miami Ear Institute, Box 016960 (D-48, Miami, FL 33101, USA
Laryngoscope 113:1266-8. 2003
Audiological features of GJB2 (connexin 26) deafnessXue Zhong Liu
Department of Otolaryngology, University of Miami, Miami, Florida 33136, USA
Ear Hear 26:361-9. 2005....
Coenzyme Q-10 treatment of patients with a 7445A--->G mitochondrial DNA mutation stops the progression of hearing lossSimon I Angeli
Department of Otolaryngology, University of Miami School of Medicine, Miami, FL 33101, USA
Acta Otolaryngol 125:510-2. 2005..One year after being diagnosed with mitochondrial hearing loss, the patient who refused CoQ10 treatment exhibited an 11-dB deterioration of his hearing thresholds. There were no side-effects related to treatment with CoQ10...
Cochlear implantation concurrent with translabyrinthine acoustic neuroma resectionSyed Ahsan
Department of Otolaryngology-Head and Neck Surgery, University of Miami, Miami, FL 33101, USA
Laryngoscope 113:472-4. 2003..CONCLUSIONS: To the best of our knowledge, this is the first case reported of simultaneous cochlear implant and translabyrinthine acoustic neuroma resection in the same ear of a patient with neurofibromatosis type 2...
Predicting behavior problems in deaf and hearing children: the influences of language, attention, and parent-child communicationDavid H Barker
Department of Psychology, University of Miami, 5665 Ponce de Leon Boulevard, Coral Gables, FL 33146 0751, USA
Dev Psychopathol 21:373-92. 2009..Language was associated with behavior problems both directly and indirectly through effects on attention. Amount of parent-child communication was not related to behavior problems...
Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient populationXiao Mei Ouyang
Department of Otolaryngology D 48, University of Miami, 1666 NW 12th Avenue, Miami, FL 33136, USA
Hum Genet 116:292-9. 2005..The present study suggests that mutations in MYO7A and CDH23 are the two major components of causes for USH1, while PCDH15, USH1C, and SANS are less frequent causes...
The prevalence of connexin 26 ( GJB2) mutations in the Chinese populationXue Zhong Liu
Department of Otolaryngology D 48, University of Miami, 1666 NW 12th Avenue, Miami, Florida 33136, USA
Hum Genet 111:394-7. 2002..The 235delC mutation, rather than 35delG, is the most common mutation found in the Chinese deaf population. Our data support the view that specific combinations of GJB2 mutation exist in different populations...
Spoken language development in children following cochlear implantationJohn K Niparko
Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
JAMA 303:1498-506. 2010..Cochlear implantation is a surgical alternative to traditional amplification (hearing aids) that can facilitate spoken language development in young children with severe to profound sensorineural hearing loss (SNHL)...
Performance after cochlear implantation in DFNB1 patientsSarah S Connell
University of Miami Ear Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Otolaryngol Head Neck Surg 137:596-602. 2007..To evaluate the speech perception and language development with cochlear implants (CI) of DFNB1 children in comparison with non-DFNB1 deaf children...
Induction of localized cochlear hypothermiaLee P Smith
Department of Otolaryngology, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
Acta Otolaryngol 127:228-33. 2007..Localized cochlear hypothermia was induced in a rat model, demonstrating the feasibility of modulating cochlear temperature without affecting core body temperature...
Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing lossAdrien A Eshraghi
Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine, University of Miami, Miami, FL, USA
Otol Neurotol 28:842-9. 2007..The progressive loss of hearing that develops after electrode insertion trauma (EIT) can be attenuated by local dexamethasone (DXM) therapy...
Benefits of bilateral cochlear implantation: a reviewKevin D Brown
Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida 33101, USA
Curr Opin Otolaryngol Head Neck Surg 15:315-8. 2007..This update reviews the basics of binaural listening and the advantages and disadvantages of binaural cochlear implantation...
Dexamethasone base conserves hearing from electrode trauma-induced hearing lossRichard J Vivero
Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136 1015, USA
Laryngoscope 118:2028-35. 2008..Local treatment of the cochlea after electrode insertion trauma with dexamethasone base conserves hearing against trauma-induced loss...
Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymphPhilip A Bird
Department of Otolaryngology, Head and Neck Surgery, Christchurch Hospital, New Zealand
Otol Neurotol 28:1124-30. 2007..To compare methylprednisolone concentrations in the perilymph of the human ear and in plasma after intratympanic (IT) or intravenous (IV) administration...
Electrode migration after cochlear implantationSarah S Connell
Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida, USA
Otol Neurotol 29:156-9. 2008..To review the occurrence of electrode migration after cochlear implantation...
Cochlear implantation in individuals with Usher type 1 syndromeXue Z Liu
Department of Otolaryngology, University of Miami, Miami, FL 33101, USA
Int J Pediatr Otorhinolaryngol 72:841-7. 2008..To analyze the occurrence of the Usher type 1 (USH1) gene mutations in cochlear implant recipients with deaf-blind Usher syndrome, and to assess the potential effect of these genes and other factors on the therapeutic outcome...
Cochlear implantation in organ transplantationD Michael Patterson
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33101, USA
Laryngoscope 118:116-9. 2008..This study was designed to retrospectively review the outcomes of cochlear implantation among organ transplant patients...
Caloric function after endolymphatic sac surgeryS Arif Ulubil
Department of Otolaryngology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
Laryngoscope 118:295-9. 2008..To evaluate the effect of endolymphatic sac surgery on vestibular functions using caloric testing on electronystagmography (ENG)...
Pattern of hearing loss in a rat model of cochlear implantation traumaAdrien A Eshraghi
Department of Otolaryngology, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA
Otol Neurotol 26:442-7; discussion 447. 2005..CONCLUSION: These results document a progressive loss of hearing acuity postimplantation and strongly suggest that electrode insertion trauma generated oxidative stress within injured cochlear tissues...
Evaluation of hearing and auditory nerve function by combining ABR, DPOAE and eABR tests into a single recording sessionMarek Polak
Department of Otolaryngology, Cochlear Implant Research Program, University of Miami Ear Institute, 1600 NW 10th Avenue, RMSB 3160, Miami, FL 33136, USA
J Neurosci Methods 134:141-9. 2004..All measurements were obtained from anesthetized laboratory rats during single recording sessions using hardware and software stimulation and analysis programs developed by Intelligent Hearing Systems, Miami, FL...
Further prospective findings with compound action potentials from Nucleus 24 cochlear implantsMarek Polak
University of Miami Ear Institute, Department of Otolaryngology, 1666 NW 10 th Ave, ACC East, Miami, FL 33131, USA
Hear Res 188:104-16. 2004....
Etiologic diagnosis of sensorineural hearing loss in adultsSimon I Angeli
Department of Otolaryngology, University of Miami School of Medicine, Florida 33101, USA
Otolaryngol Head Neck Surg 132:890-5. 2005..To determine the etiology of adult-onset sensorineural hearing loss...
Cochlear temperature correlates with both temporalis muscle and rectal temperatures. Application for testing the otoprotective effect of hypothermiaAdrien A Eshraghi
Department of Otolaryngology, University of Miami, Miami, Florida 33136, USA
Acta Otolaryngol 125:922-8. 2005..RESULTS: The strongest correlations with the internal temperature of the cochlea during the induction of mild-to-moderate hypothermia were obtained for the temperatures of the ipsilateral temporalis muscle and rectum...
Changes in programming over time in postmeningitis cochlear implant usersAdrien A Eshraghi
University of Miami School of Medicine, Department of Otolaryngology, University of Miami Eear Institute, Florida, USA
Otolaryngol Head Neck Surg 131:885-9. 2004..This study evaluated changes in programming for patients deafened by bacterial meningitis and stability of auditory performance over time...
Revision cochlear implantation for facial nerve stimulation in otosclerosisMarek Polak
University of Miami Ear Institute, Miami, FL, USA
Arch Otolaryngol Head Neck Surg 132:398-404. 2006....
D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation traumaAdrien A Eshraghi
Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida 33136-1015, USA
Otol Neurotol 27:504-11. 2006..CONCLUSION: Hearing loss caused by cochlear implant electrode insertion trauma in guinea pigs has both acute and delayed components. The delayed component can be prevented by treating the cochlea with D-JNKI-1...
Phase III clinical trial results with the Vibrant Soundbridge implantable middle ear hearing device: a prospective controlled multicenter studyCharles M Luetje
Otologic Center, Inc, Kansas City, MO 64111, USA
Otolaryngol Head Neck Surg 126:97-107. 2002..The goal of the study was to evaluate the performance of a semi-implantable middle ear hearing device (Vibrant Soundbridge System [VSB]; Symphonix Devices, Inc)...
Comparative study of cochlear damage with three perimodiolar electrode designsAdrien A Eshraghi
Department of Otolaryngology, Medical School, University of Miami Ear Institute, Miami, FL 33131, USA
Laryngoscope 113:415-9. 2003..To describe intracochlear insertion trauma caused by three perimodiolar cochlear implant electrodes...
Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantationUlysses Scarpidis
Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York, USA
Otol Neurotol 24:409-17. 2003..CONCLUSION: Blocking the JNK/c-Jun cell death pathway is a feasible approach to treating oxidative stress-induced apoptosis within the cochlea and may have application as an otoprotective strategy during cochlear implantation...
Pediatric tympanoplasty: effect of contralateral ear status on outcomesWilliam O Collins
Department of Otolaryngology, University of Miami School of Medicine, Miami, Fla, USA
Arch Otolaryngol Head Neck Surg 129:646-51. 2003....
Vestibular effects of cochlear implantationCraig A Buchman
Department of Otolaryngology, University of North Carolina at Chapel Hill, 27599 7600, USA
Laryngoscope 114:1-22. 2004..As candidate profiles continue to evolve and with the recent development of bilateral CI, understanding the significance of this risk takes on an increasing importance...
Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitroJose Guzman
University of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL 33136, USA
Acta Otolaryngol 126:685-90. 2006....
Facial nerve stimulation after cochlear implantationJennifer L Smullen
University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33101, USA
Laryngoscope 115:977-82. 2005..All devices had a similar incidence of FNS, but perimodiolar electrodes produced FNS only at significantly higher loudness levels than straight electrodes, making them preferable for patients at risk for FNS receiving Nucleus devices...
Mild hypothermia protects auditory function during cochlear implant surgeryThomas J Balkany
Department of Otolaryngology, University Ear Institute, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, USA
Laryngoscope 115:1543-7. 2005..However, the hypothermia group had significantly less functional loss in the immediate stage and no significant loss in the progressive stage. CONCLUSION: Mild hypothermia protects auditory function during CI electrode insertion...
Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicityAdrien A Eshraghi
Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, RMSB 3160, Miami, FL 33136 1015, USA
Hear Res 226:168-77. 2007..This unique therapeutic approach may have clinical application for preventing: (1) hearing loss caused by neomycin ototoxicity; and (2) the progressive component of electrode insertion trauma-induced hearing loss...
Vibrant soundbridge surgery: evaluation of transcanal surgical approachesEric Truy
Département d ORL, de Chirurgie Maxillo Cervico Faciale et d Audiophonologie, Hopital Edouard Herriot, Lyon, France
Otol Neurotol 27:887-95. 2006..e., facial palsy and/or taste disturbance. The purpose of this study is to develop and compare transcanal surgical approaches for leading the VSB into the middle ear...
Cochlear implantsSarah S Connell
Department of Otolaryngology, University of Miami Ear Institute, Miller School of Medicine, PO Box 016960, Miami, FL 33101, USA
Clin Geriatr Med 22:677-86. 2006..Cochlear implantation in the elderly is well tolerated and provides marked improvement in auditory performance and psychosocial functioning...
Giant mastoid osteoma with postoperative high-frequency sensorineural hearing lossRaymond E Lee
Department of Otolaryngology Head and Neck Surgery, University of Miami, FL 33136, USA
Ear Nose Throat J 87:23-5. 2008..This case study presents clinical, radiologic, intraoperative, pathologic, and audiometric findings of a mastoid osteoma and a review of the literature...
