Research Topics
| ANN LINDA BALDWINSummaryAffiliation: University of Arizona Country: USA Publications
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Publications
Are investigators aware of environmental noise in animal facilities and that this noise may affect experimental data?Ann L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ, USA
J Am Assoc Lab Anim Sci 46:45-51. 2007..On the basis of the findings of this survey, we present recommendations for improving the environment, particularly for decreasing the noise level, in animal facilities...
Physiological changes in energy healers during self-practiceANN LINDA BALDWIN
Laboratory for the Advances in Consciousness and Health, Department of Psychology, University of Arizona, Tucson, AZ 85721 0068, USA
Complement Ther Med 20:299-305. 2012..This study assessed self practice-related changes in autonomic nervous system (ANS) activity in Reiki Masters and advanced Reconnective Healers...
The Touchstone Process: an ongoing critical evaluation of reiki in the scientific literatureAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
Holist Nurs Pract 24:260-76. 2010..Reiki is used by a growing number of people but little is known about the scientific basis for its use...
Reiki improves heart rate homeostasis in laboratory ratsANN LINDA BALDWIN
Laboratory for the Advances in Consciousness and Health, Department of Psychology, University of Arizona, Tucson, AZ 85721 0068, USA
J Altern Complement Med 14:417-22. 2008..To determine whether application of Reiki to noise-stressed rats can reduce their heart rates (HRs) and blood pressures...
Effect of noise on microvascular integrity in laboratory ratsAnn L Baldwin
Department of Physiology, University of Arizona, Tucson, AZ, USA
J Am Assoc Lab Anim Sci 46:58-65. 2007..Thus exposure of rats to excessive noise produces structural damage in the mesenteric microvasculature that is significantly reduced by dietary supplements...
Effect of noise on the morphology of the intestinal mucosa in laboratory ratsAnn L Baldwin
Department of Physiology, University of Arizona and Veterans Administration Medical Center, Tucson, AZ, USA
J Am Assoc Lab Anim Sci 45:74-82. 2006....
Personal interaction with a Reiki practitioner decreases noise-induced microvascular damage in an animal modelAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724 5051, USA
J Altern Complement Med 12:15-22. 2006..To determine whether Reiki, a process of transmission of healing energy, can significantly reduce microvascular leakage caused by exposure to excessive noise using an animal model...
Effects of phosphorothioate oligodeoxynucleotide on hemoglobin-induced damage to intestinal mucosaAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85724 5051, USA
Artif Cells Blood Substit Immobil Biotechnol 33:163-86. 2005..Thus, PS-ODN, although an iron chelator, can significantly enhance epithelial damage caused by DBBF-Hb in the rat intestinal mucosa near Peyer's patches, possibly by formation of the ferryl component of the hemoglobin...
Blood substitutes and redox responses in the microcirculationAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724 5051, USA
Antioxid Redox Signal 6:1019-30. 2004..Finally, several possible cell signaling pathways that are triggered in endothelial cells, in response to modified hemoglobins, are considered in terms of protecting microvascular function...
Modified hemoglobins produce venular interendothelial gaps and albumin leakage in the rat mesenteryA L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85724 5051, USA
Am J Physiol 277:H650-9. 1999..These Hbs appear to induce venular leakage in the mesentery by mechanisms similar to those previously observed after treatment with histamine or nitric oxide synthase inhibitors...
Introduction: a brief history of capillaries and some examples of their apparently strange behaviourA L Baldwin
Department of Physiology College of Medicine, University, of Arizona, Tucson, 85724 5051, USA
Clin Exp Pharmacol Physiol 27:821-5. 2000..3. The following papers will provide insight into the expanded appreciation of the varied nature of capillaries and how their functions are co-ordinated to achieve 'whole organ' exchange...
Comparison of effects of two hemoglobin-based O(2) carriers on intestinal integrity and microvascular leakageAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson 85724 5051, USA
Am J Physiol Heart Circ Physiol 283:H1292-301. 2002..These results indicate that intravascular PolyHbBv produces significantly less disruption of the intestinal exchange barrier than does DBBF-Hb, probably because the heme is not so easily oxidized...
Differential effects of sodium selenite in reducing tissue damage caused by three hemoglobin-based oxygen carriersAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85724 5051, USA
J Appl Physiol 96:893-903. 2004....
Sodium selenite reduces hemoglobin-induced venular leakage in the rat mesenteryAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson 85724 5051, USA
Am J Physiol Heart Circ Physiol 284:H81-91. 2003..In vitro, Na(2)SeO(3) reduced the oxidation rate of DBBF-Hb while in the presence of oxidants. These results suggest that Na(2)SeO(3) reduces DBBF-Hb-induced microvascular leakage partly by retarding the oxidation of its heme iron...
Effects of S-nitrosation on hemoglobin-induced microvascular damageTara K Burke
Program of Biomedical Engineering, University of Arizona, Tucson, 85724, USA
Antioxid Redox Signal 8:1093-101. 2006..005). In conclusion, NO, or a related vasodilator, when released from SNO-Hb, significantly reduces but does not eliminate microvascular damage. Further improvements may result by S-nitrosating a more stable form of modified hemoglobin...
Selenium reduces hemoglobin-induced epithelial damage to intestinal mucosaAnn L Baldwin
Department of Physiology, College of Medicine, University of Arizona, Tucson 85724-5051, USA
Artif Cells Blood Substit Immobil Biotechnol 30:1-22. 2002..27+/-2.40 and 1.48+/-1.70 for DBBF-Hb and HBS-BSA, respectively). Since mast cell mediators damage cells, Se must protect the mucosal epithelium in some way...
Disodium cromoglycate stabilizes mast cell degranulation while reducing the number of hemoglobin-induced microvascular leaks in rat mesenteryMaxwell I Ginsburg
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85724-5051, USA
Am J Physiol Heart Circ Physiol 286:H1750-6. 2004..These results suggest mast cell degranulation is not a major contributor to microvascular leakage induced by DBBF-Hb...
Role of the actin cytoskeleton in regulating endothelial permeability in venulesJ Edward Valeski
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724 5051, USA
Microcirculation 10:411-20. 2003..This study was performed to determine the effect of myosin light chain kinase (MLCK) inhibition on histamine- and thrombin-induced venular permeability in the rat mesentery, coincidental with actin cytoskeleton changes...
Are laboratory animals stressed by their housing environment and are investigators aware that this stress can affect physiological data?Meera Jain
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona 85724 5051, USA
Med Hypotheses 60:284-9. 2003....
Knockout mice: is it just genetics? Effect of enriched housing on fibulin-4(+/-) miceElizabeth Cudilo
Department of Physiology, College of Medicine, University of Arizona, Tucson, Arizona, United States of America
PLoS ONE 2:e229. 2007..After preliminary experiments were performed, a second purpose developed, which was to test the hypothesis that any observed pathologies would be ameliorated by housing the animals in enriched cages...
Mast cell activation by stressAnn L Baldwin
Department of Physiology, University of Arizona, Tucson, AZ, USA
Methods Mol Biol 315:349-60. 2006..This topic is addressed in this chapter. In addition, two histological techniques are described to visualize connective tissue and mucosal mast cells and to assess their degree of degranulation...
Effects of pulsation frequency and endothelial integrity on enhanced arterial transmural filtration produced by pulsatile pressureJonathan P Alberding
Biomedical Engineering Program, Arizona Health Sciences Center, Tucson, AZ, USA
Am J Physiol Heart Circ Physiol 289:H931-7. 2005..The observed responses of arteries to pulsatile pressure, with and without endothelium, or undergoing a frequency change, suggest a dynamic role for the endothelium in regulating transvascular transport in vivo...
Do audible and ultrasonic sounds of intensities common in animal facilities affect the autonomic nervous system of rodents?Anora K Burwell
Department of Physiology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
J Appl Anim Welf Sci 9:179-200. 2006..Because the cardiovascular, respiratory, renal, and gastrointestinal systems are under autonomic control, such noise could have wide-ranging effects on animal physiology...
