S P Balashov


Affiliation: University of California
Country: USA


  1. Siletsky S, Mamedov M, Lukashev E, Balashov S, Dolgikh D, Rubin A, et al. Elimination of proton donor strongly affects directionality and efficiency of proton transport in ESR, a light-driven proton pump from Exiguobacterium sibiricum. Biochim Biophys Acta Bioenerg. 2019;1860:1-11 pubmed publisher
    ..This indicates that overall proton transport results from competition of forward and reverse reactions, and emphasizes the importance of internal donor for high efficiency and directionality of H+ transfer. ..
  2. Siletsky S, Mamedov M, Lukashev E, Balashov S, Dolgikh D, Rubin A, et al. Electrogenic steps of light-driven proton transport in ESR, a retinal protein from Exiguobacterium sibiricum. Biochim Biophys Acta. 2016;1857:1741-1750 pubmed publisher
    ..The features of the photoelectric potential generation correlate with the ESR structure and proposed mechanism of proton transfer. ..
  3. Balashov S, Imasheva E, Boichenko V, Antón J, Wang J, Lanyi J. Xanthorhodopsin: a proton pump with a light-harvesting carotenoid antenna. Science. 2005;309:2061-4 pubmed
    ..The antenna carotenoid extends the wavelength range of the collection of light for uphill transmembrane proton transport. ..
  4. Balashov S, Imasheva E, Lanyi J. Induced chirality of the light-harvesting carotenoid salinixanthin and its interaction with the retinal of xanthorhodopsin. Biochemistry. 2006;45:10998-1004 pubmed
    ..The observed spectral features suggest that binding of salinixanthin in xanthorhodopsin involves the cyclohexenone ring of the carotenoid and its conformational heterogeneity is restricted. ..
  5. request reprint
    Balashov S, Lanyi J. Xanthorhodopsin: Proton pump with a carotenoid antenna. Cell Mol Life Sci. 2007;64:2323-8 pubmed
    ..Antenna addition to a retinal protein has not been observed among the archaea and emerged in bacteria apparently in response to environmental conditions where light-harvesting becomes a limiting factor in retinal protein functioning. ..
  6. Balashov S, Imasheva E, Wang J, Lanyi J. Excitation energy-transfer and the relative orientation of retinal and carotenoid in xanthorhodopsin. Biophys J. 2008;95:2402-14 pubmed publisher
    ..The results establish xanthorhodopsin as the simplest biological excited-state donor-acceptor system for collecting light...
  7. Balashov S, Imasheva E, Choi A, Jung K, Liaaen Jensen S, Lanyi J. Reconstitution of gloeobacter rhodopsin with echinenone: role of the 4-keto group. Biochemistry. 2010;49:9792-9 pubmed publisher
    ..We suggest that the 4-keto group in salinixanthin and echinenone allows for the twisted conformation of the ring around the C6-C7 bond and probably is engaged in an interaction that locks the carotenoid in the binding site. ..