G L Bakris

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint Hypertension in 2011: New insights--from risk factors to treatment implications
    George L Bakris
    Hypertensive Diseases Unit, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago Pritzker School of Medicine, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA
    Nat Rev Cardiol 9:75-7. 2012
  2. doi request reprint Review of blood pressure control rates and outcomes
    George Bakris
    ASH Comprehensive Hypertension Center, The University of Chicago Medicine, Chicago, IL Electronic address
    J Am Soc Hypertens 8:127-41. 2014
  3. pmc Recognition, pathogenesis, and treatment of different stages of nephropathy in patients with type 2 diabetes mellitus
    George L Bakris
    University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Mayo Clin Proc 86:444-56. 2011
  4. ncbi request reprint Differences in glucose tolerance between fixed-dose antihypertensive drug combinations in people with metabolic syndrome
    George Bakris
    Department of Preventive Medicine, Rush University Hypertension Center, Chicago, IL 60612, USA
    Diabetes Care 29:2592-7. 2006
  5. doi request reprint Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy
    George Bakris
    Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
    Kidney Int 74:364-9. 2008
  6. doi request reprint Risk factor assessment for new onset diabetes: literature review
    George Bakris
    Hypertension Center, Section of Endocrinology, Diabetes, and Metabolism, University of Chicago, Pritzker School of Medicine, Chicago, IL 60612, USA
    Diabetes Obes Metab 11:177-87. 2009
  7. ncbi request reprint Beta blockers in the management of chronic kidney disease
    G L Bakris
    Department of Medicine, Hypertension Center, Endocrine Division, University of Chicago School of Medicine, Chicago, Illinois 60637, USA
    Kidney Int 70:1905-13. 2006
  8. doi request reprint Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study
    G L Bakris
    Hypertensive Diseases Unit, Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Kidney Int 73:1303-9. 2008
  9. ncbi request reprint Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial
    G L Bakris
    Department of Medicine, Hypertension Center, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637, USA
    Kidney Int 72:879-85. 2007
  10. ncbi request reprint Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy
    G L Bakris
    Rush University Hypertension Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Kidney Int 54:1283-9. 1998

Collaborators

Detail Information

Publications66

  1. doi request reprint Hypertension in 2011: New insights--from risk factors to treatment implications
    George L Bakris
    Hypertensive Diseases Unit, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Chicago Pritzker School of Medicine, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA
    Nat Rev Cardiol 9:75-7. 2012
    ....
  2. doi request reprint Review of blood pressure control rates and outcomes
    George Bakris
    ASH Comprehensive Hypertension Center, The University of Chicago Medicine, Chicago, IL Electronic address
    J Am Soc Hypertens 8:127-41. 2014
    ..Although many patients reach BP goal, combination antihypertensive therapy is often needed to reach BP goal. Effective BP lowering has been shown to result in improvements in CV outcomes. ..
  3. pmc Recognition, pathogenesis, and treatment of different stages of nephropathy in patients with type 2 diabetes mellitus
    George L Bakris
    University of Chicago Pritzker School of Medicine, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Mayo Clin Proc 86:444-56. 2011
    ..Regular and comprehensive follow-up assessments with appropriate adjustment of the therapeutic regimen to maintain risk factor control is a vital component of care, including referral to specialists, when required...
  4. ncbi request reprint Differences in glucose tolerance between fixed-dose antihypertensive drug combinations in people with metabolic syndrome
    George Bakris
    Department of Preventive Medicine, Rush University Hypertension Center, Chicago, IL 60612, USA
    Diabetes Care 29:2592-7. 2006
    ....
  5. doi request reprint Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy
    George Bakris
    Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
    Kidney Int 74:364-9. 2008
    ..We conclude that telmisartan is superior to losartan in reducing proteinuria in hypertensive patients with diabetic nephropathy, despite a similar reduction in blood pressure...
  6. doi request reprint Risk factor assessment for new onset diabetes: literature review
    George Bakris
    Hypertension Center, Section of Endocrinology, Diabetes, and Metabolism, University of Chicago, Pritzker School of Medicine, Chicago, IL 60612, USA
    Diabetes Obes Metab 11:177-87. 2009
    ..Patients with MS may be at lower risk of diabetes when using a FDC calcium channel blocker + angiotensin-converting enzyme inhibitor compared with an angiotensin receptor blocker + TD...
  7. ncbi request reprint Beta blockers in the management of chronic kidney disease
    G L Bakris
    Department of Medicine, Hypertension Center, Endocrine Division, University of Chicago School of Medicine, Chicago, Illinois 60637, USA
    Kidney Int 70:1905-13. 2006
    ..It is apparent that greater use of this drug class for blood pressure control would further enhance reduction of risk of heart failure, the most common cause of death in the first year of starting dialysis...
  8. doi request reprint Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study
    G L Bakris
    Hypertensive Diseases Unit, Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Kidney Int 73:1303-9. 2008
    ..The dissociation between reductions in blood pressure and albuminuria may be related to factors other than blood pressure...
  9. ncbi request reprint Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial
    G L Bakris
    Department of Medicine, Hypertension Center, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637, USA
    Kidney Int 72:879-85. 2007
    ..Our results suggest that patients with cardiovascular risk and relatively low albumin excretion rates in early-stage disease may only require monotherapy with renin-angiotensin-aldosterone blocking agents...
  10. ncbi request reprint Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy
    G L Bakris
    Rush University Hypertension Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Kidney Int 54:1283-9. 1998
    ..Both angiotensin converting enzyme (ACE) inhibitors and the nondihydropyridine calcium antagonists, (non-DHPCAs) reduce both arterial pressure and proteinuria in those with diabetic nephropathy...
  11. ncbi request reprint Rationale and design of a study comparing two fixed-dose combination regimens to reduce albuminuria in patients with type II diabetes and hypertension
    G L Bakris
    Department of Preventive and Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Hum Hypertens 19:139-44. 2005
    ..Other objectives include a comparison of the proportion of patients who progress to overt diabetic nephropathy and the safety of these two combination therapies in these high-risk patients...
  12. ncbi request reprint Benefits of combination angiotensin-converting enzyme inhibitor and calcium antagonist therapy for diabetic patients
    G R Sheinfeld
    Department of Medicine, University of Illinois at Chicago Medical Center, USA
    Am J Hypertens 12:80S-85S. 1999
    ..This paper reviews the importance of aggressive blood pressure control in diabetic patients and the clinical trials supporting the use of combination ACE inhibitor/calcium antagonist therapy in the diabetic patient population...
  13. ncbi request reprint Effect of calcium channel or beta-blockade on the progression of diabetic nephropathy in African Americans
    G L Bakris
    Department of Medicine, Ochsner Clinic, New Orleans, LA, USA
    Hypertension 29:744-50. 1997
    ....
  14. ncbi request reprint Angiotensin-converting enzyme inhibitor-associated elevations in serum creatinine: is this a cause for concern?
    G L Bakris
    Rush University Hypertension Clinical Research Center, Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Arch Intern Med 160:685-93. 2000
    ..However, many physicians fail to use ACEIs or angiotensin receptor blockers in patients with renal insufficiency for fear that either serum creatinine or potassium levels will rise...
  15. ncbi request reprint A practical approach to achieving recommended blood pressure goals in diabetic patients
    G L Bakris
    Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Rush University Hypertension Center, 1700 W Van Buren, Suite 470, Chicago, IL 60612, USA
    Arch Intern Med 161:2661-7. 2001
    ..A case study that applies these concepts in outpatient practice is included...
  16. ncbi request reprint Protection of the kidney by thiazolidinediones: an assessment from bench to bedside
    P A Sarafidis
    Department of Preventive Medicine, Hypertension Clinical Research Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Kidney Int 70:1223-33. 2006
    ..This paper summarizes all the data from clinical and experimental studies relevant to a possible renoprotective effect of TZDs and discusses actions of these compounds that may contribute toward this effect...
  17. ncbi request reprint Antihypertensive treatment with beta-blockers and the spectrum of glycaemic control
    P A Sarafidis
    Hypertension Clinical Research Center, Department of Preventive Medicine, Rush University Medical Center, 1700 West Van Buren, Suite 470, Chicago, IL 60612, USA
    QJM 99:431-6. 2006
    ....
  18. ncbi request reprint The role of combination antihypertensive therapy and the progression of renal disease hypertension: looking toward the next millennium
    G L Bakris
    Rush University Hypertension Center, Department of Preventive Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA
    Am J Hypertens 11:158S-162S. 1998
    ..Certain types of angiotensin-converting enzyme inhibitors, as well as calcium channel antagonist combinations, however, appear to have better overall effects than others do. These and related data are reviewed in this paper...
  19. ncbi request reprint Comparison of telmisartan vs. valsartan in the treatment of mild to moderate hypertension using ambulatory blood pressure monitoring
    George Bakris
    Department of Preventive Medicine and Internal Medicine, Rush Hypertension Clinical Research Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    J Clin Hypertens (Greenwich) 4:26-31. 2002
    ..These data suggest greater efficacy for telmisartan than valsartan in controlling blood pressure throughout the 24-hour dosing interval, including the last 6 hours before dosing, and the two agents were similarly well tolerated...
  20. ncbi request reprint beta-blocker use and diabetes symptom score: results from the GEMINI study
    J B McGill
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Diabetes Obes Metab 9:408-17. 2007
    ..In this paper, we report the results of a prespecified secondary analysis of GEMINI that sought to determine the effect of these two beta-blockers on commonly reported symptoms...
  21. ncbi request reprint ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group
    G L Bakris
    Hypertension Clinical Research Center, Rush University, Chicago, Illinois 60612, USA
    Kidney Int 58:2084-92. 2000
    ..No study has evaluated the comparative effects of an angiotensin-converting enzyme (ACE) inhibitor versus an angiotensin receptor blocker (ARB) on the changes in serum [K(+)] in people with renal insufficiency...
  22. ncbi request reprint Microalbuminuria: what is it? Why is it important? What should be done about it?
    G L Bakris
    Rush University Hypertension Center, Rush Presbyterian St Luke s Medical Center, 1700 West Van Buren Street, Chicago, IL 60612, USA
    J Clin Hypertens (Greenwich) 3:99-102. 2001
    ..c)2001 by Le Jacq Communications, Inc...
  23. ncbi request reprint Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study
    George Bakris
    University of Chicago Pritzker School of Medicine, Chicago, IL 60612, USA
    J Cardiometab Syndr 3:18-25. 2008
    ..0 vs 7.2+/-2.3; P<.001). This exploratory study suggests that the impairment in glycemic control seen with use of a thiazide diuretic combined with a RASI can be reversed by switching to a regimen that does not include a diuretic...
  24. ncbi request reprint A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes
    George Bakris
    Department of Preventive Medicine, Rush Hypertension Clinical Research Center, Chicago, Illinois, USA
    Am J Hypertens 15:53-7. 2002
    ....
  25. ncbi request reprint Angiotensin-converting enzyme inhibition to enhance vascular health--clinical and research models
    G L Bakris
    Department of Preventive Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA
    Am J Hypertens 14:264S-269S. 2001
    ..An issue to resolve is how much ACE inhibition is needed at the tissue level to reverse or prevent further vascular damage...
  26. doi request reprint Limitations of metformin use in patients with kidney disease: are they warranted?
    K P Vasisht
    Division of Adult Endocrinology, Diabetes and Metabolism, and Hypertensive Diseases Unit, University of Chicago Hospitals, Chicago, IL 60637, USA
    Diabetes Obes Metab 12:1079-83. 2010
    ..We evaluated metformin use in two cohorts, one from the University of Chicago Diabetes Center and the other from National Health and Nutrition Examination Survey (NHANES) 1999-2006...
  27. ncbi request reprint Calcium antagonism abolishes the antipressor action of vasopressin (V1) receptor antagonism
    G L Bakris
    Rush University Hypertension Center, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA
    Am J Hypertens 10:1153-8. 1997
    ..We conclude that calcium channel blockade abolishes the blood pressure lowering response of V1 receptor blockade in blacks...
  28. doi request reprint Management of hypertension in patients with diabetes: the place of angiotensin-II receptor blockers
    Rigas Kalaitzidis
    Hypertensive Diseases Unit, Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
    Diabetes Obes Metab 11:757-69. 2009
    ..Based on these findings, contemporary treatment guidelines recommend a target SBP/diastolic blood pressure of <130/80 mmHg for patients with diabetes...
  29. doi request reprint The diabetes subgroup baseline characteristics of the Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial
    George Bakris
    Hypertensive Diseases Unit, Department of Medicine, University of Chicago School of Medicine, Chicago, IL 60637, USA
    J Cardiometab Syndr 3:229-33. 2008
    ..8% of DM patients had blood pressure levels <130/80 mm Hg. ACCOMPLISH will provide valuable guidance on optimizing treatment strategies in hypertensive patients at high cardiovascular risk with and without DM...
  30. ncbi request reprint Blood pressure, antihypertensive therapy and risk for renal injury in African-Americans
    Nicholas Kaperonis
    Department of Preventive Medicine, Rush University Hypertension Clinical Research Center, Rush Medical College, Chicago, Illinois 60612, USA
    Curr Opin Nephrol Hypertens 12:79-84. 2003
    ....
  31. ncbi request reprint Non-esterified fatty acids and blood pressure elevation: a mechanism for hypertension in subjects with obesity/insulin resistance?
    P A Sarafidis
    Department of Preventive Medicine, Hypertension Clinical Research Center, Rush University Medical Center, Chicago, IL 60612, USA
    J Hum Hypertens 21:12-9. 2007
    ..The above data support a possible important role of NEFA in hypertension development in patients with obesity and the metabolic syndrome and raise hypotheses for future research...
  32. ncbi request reprint Salt intake and reductions in arterial pressure and proteinuria. Is there a direct link?
    G L Bakris
    Rush University Hypertension Center, Department of Preventive Medicine Rush Medical School, Chicago, Illinois 60612, USA
    Am J Hypertens 9:200S-206S. 1996
    ....
  33. doi request reprint Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program
    P A McCullough
    Department of Medicine, Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Intern Med J 40:833-41. 2010
    ..Coronary artery disease (CAD) identifies the need for intensive treatment of risk factors among individuals with chronic kidney disease (CKD), a high-risk, complex cardiovascular risk state...
  34. ncbi request reprint Rationale and design of a study to evaluate management of proteinuria in patients at high risk for vascular events: the IMPROVE trial
    G L Bakris
    Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    J Hum Hypertens 20:693-700. 2006
    ....
  35. doi request reprint Influence of microalbuminuria in achieving blood pressure goals
    Irena Duka
    Department of Medicine, Hypertensive Diseases Unit, Section of Endocrinology, Diabetes and Metabolism, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    Curr Opin Nephrol Hypertens 17:457-63. 2008
    ....
  36. ncbi request reprint Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial
    Jackson T Wright
    Case Western Reserve University, Department of Medicine, University Hospitals of Cleveland and the Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106 5014, USA
    JAMA 288:2421-31. 2002
    ..Hypertension is a leading cause of end-stage renal disease (ESRD) in the United States, with no known treatment to prevent progressive declines leading to ESRD...
  37. ncbi request reprint Renal hemodynamics in radiocontrast medium-induced renal dysfunction: A role for dopamine-1 receptors
    G L Bakris
    Rush University Hypertension Center, Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Kidney Int 56:206-10. 1999
    ..This lack of renoprotection may relate to nonspecific adrenergic stimulation by DA. The effect of select DA-1 receptor stimulation on renal hemodynamics following RCM administration has not been evaluated...
  38. doi request reprint Calcium antagonists: Do they equally protect against kidney injury?
    P Hart
    1Department of Medicine, Division of Nephrology and Hypertension, Cook County Hospital, Chicago, Illinois, USA
    Kidney Int 73:795-6. 2008
    ..These differences translate into different renal hemodynamic effects. This Commentary discusses the implications of these differences for surrogate markers of outcome...
  39. doi request reprint Are renin-angiotensin-aldosterone system blockers distinguishable based on cardiovascular and renal outcomes in nephropathy?
    Rigas Kalaitzidis
    Hypertensive Disease Unit, University of Chicago School of Medicine, Chicago, IL 60637, USA
    Postgrad Med 121:77-88. 2009
    ..Whether ARBs can reduce incident diabetes and related cardiovascular outcomes is awaited with the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial...
  40. doi request reprint Pathogenesis and treatment of microalbuminuria in patients with diabetes: the road ahead
    Rigas Kalaitzidis
    Department of Medicine, University of Chicago, IL 60637, USA
    J Clin Hypertens (Greenwich) 11:636-43. 2009
    ..It remains to be determined whether targeting the underlying inflammatory process can retard or prevent microalbuminuria progression or whether treatment of microalbuminuria can prevent end-stage renal disease or death...
  41. doi request reprint An in-depth analysis of vasodilation in the management of hypertension: focus on adrenergic blockade
    George Bakris
    Department of Medicine, Hypertensive Diseases Unit, University of Chicago Medical Center, Chicago, IL 60637, USA
    J Cardiovasc Pharmacol 53:379-87. 2009
    ....
  42. ncbi request reprint Orlistat improves blood pressure control in obese subjects with treated but inadequately controlled hypertension
    George Bakris
    Rush University Hypertension Clinical Research Center, Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    J Hypertens 20:2257-67. 2002
    ..DESIGN This was a 1-year, prospective, randomized, double-blind, placebo-controlled, multicenter trial of orlistat plus diet versus placebo plus diet in obese hypertensives...
  43. ncbi request reprint Effects of drospirenone/17-beta estradiol on blood pressure and potassium balance in hypertensive postmenopausal women
    Richard A Preston
    Division of Clinical Pharmacology and Pharmacokinetics Clinical Research Center, Department of Medicine, University of Miami School of Medicine, Miami, Florida, USA
    Am J Hypertens 18:797-804. 2005
    ..Because of a significant aldosterone antagonist activity, we studied the effects of DRSP/E2 on serum potassium (K) and blood pressure (BP) in hypertensive postmenopausal women with and without diabetes mellitus...
  44. ncbi request reprint Impact of an ACE inhibitor and calcium antagonist on microalbuminuria and lipid subfractions in type 2 diabetes: a randomised, multi-centre pilot study
    G L Bakris
    Department of Preventive Medicine, Rush Hypertension Clinical Research Center, Chicago, IL 60612, USA
    J Hum Hypertens 16:185-91. 2002
    ....
  45. ncbi request reprint Is ethnicity a factor in choice of antihypertensive drug?
    George Bakris
    Department of Preventive Medicine, Rush Hypertension Clinical Research Center, Rush University Medical Center, Chicago, USA
    Postgrad Med 117:40. 2005
  46. ncbi request reprint Lessons learned from recent hypertension trials about kidney disease
    Nitin Khosla
    Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Clin J Am Soc Nephrol 1:229-35. 2006
  47. doi request reprint Are there effects of renin-angiotensin system antagonists beyond blood pressure control?
    George Bakris
    Hypertensive Diseases Unit, Section of Endocrinology, Diabetes, and Metabolism, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    Am J Cardiol 105:21A-9A. 2010
    ..Therefore, although antihypertensive efficacy is of primary importance in choosing a treatment to provide cardiovascular and renal protection, consideration should be given to the effects of an agent that extend beyond blood pressure...
  48. ncbi request reprint When to refer patients to a nephrologist?
    George Bakris
    Departments of Preventive Medicine and Internal Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, USA
    Postgrad Med 113:11. 2003
  49. ncbi request reprint How to adjust ACE inhibitors and ARBs in diabetes?
    George Bakris
    Departments of Preventive Medicine and Internal Medicine, Rush Hypertension Center, Rush Presbyterian St Luke s Medical Center, Chicago, USA
    Postgrad Med 115:9-10. 2004
  50. pmc Sociodemographic factors contribute to the depressive affect among African Americans with chronic kidney disease
    Michael J Fischer
    Department of Medicine, Jesse Brown VA Medical Center and University of Illinois Medical Center, Chicago, Illinois, USA
    Kidney Int 77:1010-9. 2010
    ..Sociodemographic factors have especially strong associations with this increased depressive affect. Because this study was conducted in an African-American cohort, its findings may not be generalized to other ethnic groups...
  51. doi request reprint Cardiovascular protection for all individuals at high risk: evidence-based best practice
    George Bakris
    Department of Medicine, Hypertensive Diseases Unit, University of Chicago Pritzker School of Medicine, Chicago, IL, USA
    Clin Res Cardiol 97:713-25. 2008
    ....
  52. doi request reprint Hypertension and CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES), 1999-2004
    Madhav V Rao
    Department of Medicine, Section of Nephrology, University of Chicago, Pritzker School of Medicine, Chicago, IL 60637, USA
    Am J Kidney Dis 51:S30-7. 2008
    ..Early identification and achievement of blood pressure goals may improve chronic kidney disease outcomes...
  53. ncbi request reprint Blood pressure control and improved cardiovascular outcomes in the International Verapamil SR-Trandolapril Study
    Giuseppe Mancia
    Clinica Medica, Dipartimento di Medicina Clinica, Prevenzione, Universita Milano Bicocca, Milan, Italy
    Hypertension 50:299-305. 2007
    ..Consistency of BP control during treatment provides additional information on the protective effect of antihypertensive treatment. Physicians need to be concerned at each visit if BP is not controlled...
  54. ncbi request reprint The continuum of blood pressure risk: when is the best time to intervene?
    George Bakris
    Curr Hypertens Rep 8:395-7. 2006
  55. ncbi request reprint The rationale and design of the AASK cohort study
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, 21205, USA
    J Am Soc Nephrol 14:S166-72. 2003
    ..Such results might eventually lead to new strategies that delay or prevent ESRD...
  56. pmc Design and statistical aspects of the African American Study of Kidney Disease and Hypertension (AASK)
    Jennifer J Gassman
    Cleveland Clinic Department of Biostatistics, Ohio, 44195, USA
    J Am Soc Nephrol 14:S154-65. 2003
    ..The main secondary patient outcome is a composite including the following events: (1) reduction in GFR by 50%, (2) end-stage renal disease, or (3) death...
  57. pmc Race and sex differences in hypertension control in CKD: results from the Kidney Early Evaluation Program (KEEP)
    Obidiugwu Kenrik Duru
    Division of General Internal Medicine Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Am J Kidney Dis 51:192-8. 2008
    ..Uncontrolled hypertension worsens CKD, and disparities in hypertension control may contribute to disparities in CKD progression...
  58. pmc A propensity-matched study of hypertension and increased stroke-related hospitalization in chronic heart failure
    Gerasimos S Filippatos
    University of Athens, Athens, Greece
    Am J Cardiol 101:1772-6. 2008
    ..81; p=0.044). In conclusion, a history of hypertension was associated with increased risk of hospitalization for stroke among patients with heart failure who were balanced in all measured baseline covariates, including blood pressure...
  59. ncbi request reprint ImmunoDip: an improved screening method for microalbuminuria
    Mayer B Davidson
    Clinical Trials Unit, Charles R Drew University, Los Angeles, Calif 90059, USA
    Am J Nephrol 24:284-8. 2004
    ..Current screening methods are suboptimal. This study evaluates a new office screening test for microalbuminuria that utilizes a monoclonal antibody against human serum albumin (ImmunoDip)...
  60. doi request reprint Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial
    Steven E Nissen
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    JAMA 299:1561-73. 2008
    ..Commonly used oral glucose-lowering agents include sulfonylureas, which are insulin secretagogues, and thiazolidinediones, which are insulin sensitizers...
  61. doi request reprint Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004
    Adam T Whaley-Connell
    University of Missouri Columbia School of Medicine and Harry S Truman VA Medical Center, Columbia, MO 65212, USA
    Am J Kidney Dis 51:S21-9. 2008
    ..Early diabetes identification through targeted screening programs is important for the development of preventive strategies...
  62. doi request reprint Executive summary: Kidney Early Evaluation Program (KEEP) 2007 Annual Data Report
    George Bakris
    Department of Medicine, Section of Nephrology, University of Chicago, Pritzker School of Medicine, Chicago, IL, USA
    Am J Kidney Dis 51:S1-2. 2008
  63. ncbi request reprint Control of blood pressure and other cardiovascular risk factors at different practice settings: outcomes of care provided to diabetic women compared to men
    Samy I McFarlane
    SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 50, Brooklyn, NY 11203, USA
    J Clin Hypertens (Greenwich) 7:73-80. 2005
    ..These observations underscore the need for better strategies for control of CVD risk in the diabetic population in general, and women in particular...
  64. ncbi request reprint George Bakris, MD: researching ways to combat hypertension. Interview by Mike Mitka
    George Bakris
    JAMA 293:1439. 2005
  65. ncbi request reprint Proteinuria: a link to understanding changes in vascular compliance?
    George Bakris
    Hypertension 46:473-4. 2005
  66. ncbi request reprint The role of hyperglycaemia and the hypercoagulable state in the pathogenesis of cardiovascular events in diabetes mellitus: implications for hypertension management
    Hoong Sern Lim
    Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England
    Curr Pharm Des 12:1567-79. 2006
    ..In this review, we discuss the relationship between hyperglycaemia and a hypercoagulable state in diabetes and the implications of this relationship for the treatment of patients with diabetes, who also commonly have hypertension...