Richard E Baker
Affiliation: University of Massachusetts Medical School
- Genetic and genomic analysis of the AT-rich centromere DNA element II of Saccharomyces cerevisiaeRichard E Baker
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Genetics 171:1463-75. 2005..Thus, the distinctive and nonrandom sequence organization of CDEII is important for centromere function and possesses informational content that could contribute to the determination of centromere identity...
- Phylogenetic analysis of fungal centromere H3 proteinsRichard E Baker
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Genetics 174:1481-92. 2006..Domain swapping between S. cerevisiae Cse4 and the noncomplementing Pichia angusta ortholog showed that species specificity could not be explained by the presence or absence of any recognized secondary structural element of the HFD...
- CENP-A targeting moves a step backRichard E Baker
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Mol Cell 33:411-3. 2009..In a recent issue of Molecular Cell, Pidoux et al. (2009) and Williams et al. (2009) identify S. pombe Scm3 as the proximate factor in the Cnp1/CENP-A deposition pathway, providing a direct connection to centromere-localized Mis16-Mis18...
- The histone fold domain of Cse4 is sufficient for CEN targeting and propagation of active centromeres in budding yeastLisa Morey
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, 55 Lake Ave. North, Worcester, MA 01655, USA
Eukaryot Cell 3:1533-43. 2004..cerevisiae, and no posttranslational modification or interaction of the NT with other kinetochore component(s) is essential for accurate chromosome segregation in budding yeast...
- Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localizationSam Stoler
Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA
Proc Natl Acad Sci U S A 104:10571-6. 2007..We suggest that S. cerevisiae Scm3 defines a previously undescribed family of fungal kinetochore proteins important for CenH3 localization...
- Assembling a Centric NucleosomeRichard Baker; Fiscal Year: 2004..Given the high conservation of centric histone H3 variants throughout evolution, the results will illuminate the problem of centromere formation and function in higher eukaryotes including humans. ..